Cerebral Oxygenation and Autoregulation in Very Preterm Infants Developing IVH During the Transitional Period: A Pilot Study by Anna Giulia Cimatti, Silvia Martini, Silvia Martini, Silvia Galletti, Silvia Galletti, Francesca Vitali, Arianna Aceti, Arianna Aceti, Giulia Frabboni, Giacomo Faldella, Giacomo Faldella, Luigi Corvaglia, Luigi Corvaglia

“…Background: The transitional period, defined as the first 72 h after preterm birth, is often characterized by a significant hemodynamic instability, which represents an important risk factor for such neurological complications of prematurity as intraventricular hemorrhage (IVH). …”
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Adverse perinatal outcomes in pregnancies affected by severe COVID-19 infectionAJOG Global Reports at a Glance by Odessa P. Hamidi, MD, Virginia Lijewski, MPH, Jeanelle Sheeder, PhD, Kristin Powell, MD, Erica Dolph, BS, Delisa Quayson, MD, Shane Reeves, MD

“…Primary outcomes included hypertensive disorders of pregnancy, cesarean delivery, fetal growth restriction, preterm birth, and neonatal intensive care unit admission. …”
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Elevated expression of Toll-like receptor 4 and cytokines in both serum and myometrium at term may serve as promising biomarkers for uterine activation preceding labor by Zixi Chen, Jinpeng Li, Wenjuan Xu, Xiaomei Wu, Fenfen Xiang, Xiaoxiao Li, Mengzhe Zhang, Jin Zheng, Xiangdong Kang, Rong Wu

“…ObjectiveIncreased inflammation and cytokine levels are considered risk factors and promoters of preterm birth (PTB). However, the regulatory mechanism of pregnancy-related inflammation remains unclear. …”
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Clinical risk factors of adverse outcomes among women with COVID-19 in the pregnancy and postpartum period: a sequential, prospective meta-analysis by Smith, ER, Oakley, E, Grandner, GW, Rukundo, G, Farooq, F, Ferguson, K, Baumann, S, Waldorf, KA, Afshar, Y, Ahlberg, M, Ahmadzia, H, Akelo, V, Aldrovandi, G, Bevilacqua, E, Bracero, N, Brandt, JS, Broutet, N, Carrillo, J, Conry, J, Cosmi, E, Crispi, F, Crovetto, F, Gil, MDM, Delgado-López, C, Divakar, H, Driscoll, AJ, Favre, G, Buhigas, IF, Flaherman, V, Gale, C, Godwin, CL, Gottlieb, S, Gratacós, E, He, S, Hernandez, O, Jones, S, Joshi, S, Kalafat, E, Khagayi, S, Knight, M, Kotloff, K, Lanzone, A, Longo, VL, Le Doare, K, Lees, C, Litman, E, Lokken, EM, Madhi, SA, Magee, LA, Martinez-Portilla, RJ

“…We found that women with comorbidities (pre-existing diabetes, hypertension, cardiovascular disease) versus those without were at higher risk for COVID-19 severity and pregnancy health outcomes (fetal death, preterm birth, low birthweight). Participants with COVID-19 and HIV were 1.74 times (95% CI: 1.12, 2.71) more likely to be admitted to the ICU. …”

Adverse perinatal outcomes associated with protease inhibitor-based antiretroviral therapy in pregnant women living with HIV: A systematic review and meta-analysis by Cowdell, I, Beck, K, Portwood, C, Sexton, H, Kumarendran, M, Brandon, Z, Kirtley, S, Hemelaar, J

“…US, European, and UK guidelines include PI-based ART as first-line regimens, but advise against the use of lopinavir/ritonavir (LPV/r)-based ART, citing an increased risk of preterm birth (PTB). We aimed to assess the risk of adverse perinatal outcomes in WLHIV receiving PI-ART and the comparative risks associated with different PI-ART regimens. …”

Epidemiology of endometriosis in women of Arab ancestry by Mousa, M

“…Women with endometriosis had a higher frequency of miscarriages, ectopic pregnancy, preterm birth, and emergency caesarean section. (2) The average diagnostic delay was 11.61 years, with single women experiencing 15.81 years of diagnosis delay. …”

International gestational age-specific centiles for umbilical artery Doppler indices: A longitudinal prospective cohort study of the INTERGROWTH-21st Project by Drukker, L, Staines-Urias, E, Villar, J, Barros, FC, Carvalho, M, Munim, S, McGready, R, Nosten, F, Berkley, JA, Norris, SA, Uauy, R, Kennedy, SH, Papageorghiou, AT

“…The healthy low-risk status of the population was confirmed by the low rates of preterm birth (4.9%) and preeclampsia (0.7%). There were no neonatal deaths and satisfactory growth, health, and motor development of the infants at 1 and 2 years of age were documented. …”

Influenza A/H1N1v in pregnancy: an investigation of the characteristics and management of affected women and the relationship to pregnancy outcomes for mother and infant. by Yates, L, Pierce, M, Stephens, S, Mill, A, Spark, P, Kurinczuk, J, Valappil, M, Brocklehurst, P, Thomas, S, Knight, M

“…Outcomes examined in hospitalised women included maternal death, admission to an intensive care unit, perinatal mortality and preterm birth. Risk factors for hospital and intensive care unit admission were examined in a full regression model. …”

Identification of risk factors, pathological changes and protein biomarkers of spontaneous preterm labour with intact membranes of Malay patients by Tan, Niu Jin

“…Spontaneous preterm labour with intact membranes (sPTL-IM) is one of the most common types of preterm birth (PTB). To date, the reliability of all available prediction tools to predict pregnant women at risk of sPTL-IM is low. …”
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Acupuncture for low back and/or pelvic pain during pregnancy: a systematic review and meta-analysis of randomised controlled trials by Tao Wang, Yi Wang, Ying Lin, Wei Dong, Zhen Shen, Jiaman Yang, Jianmei Xu, Zhiwen Ou, Ting Yue, Zhitao Mao

“…However, there was no significant difference for analgesic consumption during the study period (OR=2.49, 95% CI: (0.08 to 80.25), p=0.61, I2=61%) and Apgar scores of newborns (OR=1.02, 95% CI: (0.37 to 2.83), p=0.97, I2 = 0%). Preterm birth from acupuncture during he study period was reported in two studies. …”
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Causal associations between Helicobacter pylori infection and pregnancy and neonatal outcomes: a two-sample Mendelian randomization study by Jialyu Huang, Yuxin Liu, Dingfei Xu, Mengyi Chen, Qiqi Xie, Jia Chen, Leizhen Xia, Lamei Yu, Qiongfang Wu, Zengming Li, Jiawei Wang, Lifeng Tian

“…Outcome data for pregnancy (miscarriage, preeclampsia-eclampsia, gestational diabetes mellitus, placental abruption, premature rupture of membranes, postpartum hemorrhage) and neonates (birthweight, gestational age, and preterm birth) were sourced from genome-wide association meta-analysis as well as the FinnGen and Early Growth Genetics Consortium. …”
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Maternal iodine status, intrauterine growth, birth outcomes and congenital anomalies in a UK birth cohort by Charles Jonathan Peter Snart, Diane Erin Threapleton, Claire Keeble, Elizabeth Taylor, Dagmar Waiblinger, Stephen Reid, Nisreen A. Alwan, Dan Mason, Rafaq Azad, Janet Elizabeth Cade, Nigel A. B. Simpson, Sarah Meadows, Amanda McKillion, Gillian Santorelli, Amanda H. Waterman, Michael Zimmermann, Paul M. Stewart, John Wright, Mark Mon-Williams, Darren Charles Greenwood, Laura J. Hardie

“…There was no evidence of associations using UIC or other birth outcomes, including stillbirth, preterm birth, ultrasound growth measures or congenital anomalies. …”
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Maternal and Neonatal Complications in Patients With Diminished Ovarian Reserve in In-Vitro Fertilization/Intracytoplasmic Sperm Injection Cycles by Shuang Han, Shuang Han, Shuang Han, Shuang Han, Shuang Han, Yiwei Zhai, Yiwei Zhai, Yiwei Zhai, Yiwei Zhai, Yiwei Zhai, Qingqing Guo, Qingqing Guo, Qingqing Guo, Qingqing Guo, Qingqing Guo, Yiming Qin, Peihao Liu, Peihao Liu, Peihao Liu, Peihao Liu, Peihao Liu

“…DOR patients also presented slightly higher incidences of preterm birth (10.9% vs. 7.5%, P = 0.174) and low birthweight (6.2% vs. 5.4%, P = 0.704) yet without statistical significances. …”
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Strengthening Health Systems in Humanitarian Settings: Multi-Stakeholder Insights on Contraception and Postabortion Care Programs in the Democratic Republic of Congo and Somalia by Nguyen Toan Tran, Nguyen Toan Tran, Janet Meyers, Bibiche Malilo, Julien Chabo, Jean-Baptiste Muselemu, Bienvenu Riziki, Patrick Libonga, Abdikani Shire, Hussein Had, Mohamed Ali, Mohamed Abdi Arab, Jama Mohamed Da'ar, Mohamed Hussein Kahow, Joseph Ege Adive, Binyam Gebru, Emily Monaghan, Catherine N. Morris, Meghan Gallagher, Virginie Jouanicot, Natacha Pougnier, Ribka Amsalu, Ribka Amsalu

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Deciphering a critical role of uterine epithelial SHP2 in parturition initiation at single cell resolution by Meng Liu, Mengjun Ji, Jianghong Cheng, Yingzhe Li, Yingpu Tian, Hui Zhao, Yang Wang, Sijing Zhu, Leilei Zhang, Xinmei Xu, Gen-Sheng Feng, Xiaohuan Liang, Haili Bao, Yedong Tang, Shuangbo Kong, Jinhua Lu, Haibin Wang, Zhongxian Lu, Wenbo Deng

“…In brief, this study provides a previously unappreciated role of the epithelium in parturition preparation and sheds lights on the prevention of preterm birth.…”
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Interpregnancy interval and adverse pregnancy outcomes among pregnancies following miscarriages or induced abortions in Norway (2008-2016): A cohort study. by Gizachew A Tessema, Siri E Håberg, Gavin Pereira, Annette K Regan, Jennifer Dunne, Maria C Magnus

“…We aimed to investigate the risk of adverse pregnancy outcomes-preterm birth (PTB), spontaneous PTB, small for gestational age (SGA) birth, large for gestational age (LGA) birth, preeclampsia, and gestational diabetes mellitus (GDM)-by interpregnancy interval (IPI) for births following a previous miscarriage or induced abortion.…”
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Obstetric and perinatal outcomes of singleton pregnancies conceived via assisted reproductive technology complicated by gestational diabetes mellitus: a prospective cohort study by Azam Kouhkan, Mohammad E. Khamseh, Reihaneh Pirjani, Ashraf Moini, Arezoo Arabipoor, Saman Maroufizadeh, Roya Hosseini, Hamid Reza Baradaran

“…Women were followed for pregnancy outcomes including pregnancy-induced hypertension (PIH), preeclampsia, antepartum hemorrhage (APH), cesarean section (CS), preterm birth (PTB), intrauterine growth restriction (IUGR), being small or large for gestational age (SGA or LGA), macrosomia, low birth weight (LBW), respiratory distress, neonatal hypoglycemia, NICU admission and perinatal mortality from antenatal visits to delivery. …”
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Impact of ambient temperature on adverse pregnancy outcomes: a birth cohort study in Fuzhou, China by Jinfeng Lin, Yan Yang, Ayinasaer Nuermaimaiti, Tingting Ye, Jingwen Liu, Zitong Zhang, Yifeng Chen, Qingyu Li, Chuancheng Wu, Baoying Liu, Rongxian Xu, Yong Xia, Jianjun Xiang, Jianjun Xiang

“…Most of them focus on preterm birth, low birth weight, and stillbirth. Other possible adverse outcomes were under-researched. …”
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Forward Genetic Dissection of Biofilm Development by <named-content content-type="genus-species">Fusobacterium nucleatum</named-content>: Novel Functions of Cell Division Proteins... by Chenggang Wu, Abu Amar Mohamed Al Mamun, Truc Thanh Luong, Bo Hu, Jianhua Gu, Ju Huck Lee, Melissa D’Amore, Asis Das, Hung Ton-That

“…It is also implicated in preterm birth and colorectal cancer. To facilitate basic studies of fusobacterial virulence, we describe here a versatile transposon mutagenesis procedure and a pilot screen for mutants defective in biofilm formation. …”
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How many low birthweight babies in low- and middle-income countries are preterm? Cuantos de los recién nacidos de bajo peso de países emergentes son pre-término? Quantos dos recém-... by Fernando C Barros, Aluísio J D Barros, José Villar, Alicia Matijasevich, Marlos R Domingues, Cesar G Victora

“…OBJECTIVE: To assess the prevalence of preterm birth among low birthweight babies in low and middle-income countries. …”
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