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781
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782
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783
Structural and mechanistic studies of herpes virus proteins
出版 2015“...The overall fold of protein suggests it to be novel compared to protein structures available in the Protein Data Bank. We present data that confirm ICP27 exists as dimer in solution, using biophysical assays. ...”
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Thesis -
784
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785
Human ACE2 receptor polymorphisms and altered susceptibility to SARS-CoV-2
出版 2022獲取全文
Journal Article -
786
Flexible estimation of temporal point processes and graphs
出版 2023“...In the recent years, there has been an increasing need of methodological and theoretical work to analyse non-standard data types, for instance, data collected on protein structures, genes interactions, social networks or physical sensors. ...”
Thesis -
787
My small world in biomedical research
出版 2011“...There were destruction of the cytoskeletal protein, structural and ultrastructural changes, as well as molecular changes of the oncogenes which enlightened the important biological discoveries of apoptosis in the cancer cells, however, not in the normal cells.The oncolytic effect of Newcastle Disease Virus AF2240 on Allografted 4T1 Breast Cancer Cells In Balb/c mice was well demonstrated and NDV-AF2240 was detected via In situ reverse transcriptase polymerase chain reaction (in situ RT-PCR), polyclonal chicken antibody and goat anti-chicken antibody conjugated with fluorescein isothiocynate (FITC) using confocal laser scanning microscopy (CLSM) and negative staining transmission electron microscopy (NSTEM). ...”
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Inaugural Lecture -
788
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789
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790
Determining structure and atomic properties of materials using resonant x-ray diffraction
出版 2015“...Traditionally these have been reserved for non-centrosymmetric protein structures, however with the trend of synthesising larger and larger small molecules, problems encountered in macromolecular crystallography leading to low resolution datasets are becoming increasingly common. ...”
Thesis -
791
Biocatalytic metal nanoparticle synthesis & investigation of catalytic properties of metal nanoparticle-enzyme hybrids
出版 2024“...Already demonstrated are examples where metal NPs can provide the electron source, by supply of a specific reduced “cofactor” molecule or by generating H<sub>2</sub>O<sub>2</sub>, required by the enzyme to carry out its selective transformation on an organic molecule. Combining protein structures and metals has also been carried out by either inserting artificial metal centres into proteins or by attaching metal NPs and enzymes together, often in the presence of a non-reactive support material, to make chemo-bio hybrids....”
Thesis -
792
Characterization of physicochemical environments of proteins
出版 2017“...I hope that the work presented here would facilitate future research into protein structures and their functions....”
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Thesis -
793
Deep learning neural network approaches for one-dimensional structure prediction from protein sequences
出版 2018“...However, because it is difficult and resource intensive to obtain the structures of proteins experimentally, it is desirable to predict protein structures directly from sequence. Machine learning methods in the past few decades, have been increasingly used as a complement to experimental approaches to predict structures from protein sequences. ...”
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Thesis -
794
Multiple crystallographic dataset analysis to explore crystallographic occupancy and the conformational states of proteins
出版 2019“...</p> <p>In chapter 2, a recently developed modelling strategy for protein structures was used to determine conformational differences between datasets. ...”
Thesis -
795
Structural elucidation of GDSL esterase of Photobacterium sp. J15
出版 2017“...Besides, the structure may contribute hugely in the field of structural biology where it may serve as a template in solving the phase problem of proteins with decent amino acid sequence identity to it via molecular replacement, where they are remain unsolvable due to low identity to the current available protein structures....”
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Thesis -
796
Structural elucidation of thermostable L2 lipase based on ground and microgravity grown crystals
出版 2012“...Evaluations of the crystal structures by using Errat and Verify 3-D showed that both crystal structures gave values that were in the acceptable range of good protein structures. From this study, it can be concluded that there was a polymorphism in L2 lipase crystals that resulted in production of two different shapes of protein crystals; Shape 1 and Shape 2. ...”
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Thesis