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Modeling protein target search in human chromosomes
Published 2021-01-01“…We use chromatin-chromatin contact data from Hi-C experiments to map the protein target-search onto a network problem. The nodes represent DNA segments and the weight of the links are proportional to measured contact probabilities. …”
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Fidelity of Cotranslational Protein Targeting to the Endoplasmic Reticulum
Published 2021-12-01Subjects: “…protein targeting…”
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Protein targets of oxidized phospholipids in endothelial cellss⃞
Published 2008-03-01Get full text
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Aberrant protein targeting activates quality control on the ribosome
Published 2023-06-01Subjects: Get full text
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Protein Targeting Into the Thylakoid Membrane Through Different Pathways
Published 2022-01-01“…Much progress has been made in identification and functional characterization of new factors involved in protein targeting into the thylakoids, and new insights into this process have been gained. …”
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Biomarkers for ragwort poisoning in horses: identification of protein targets
Published 2008-08-01Get full text
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Binding of omeprazole to protein targets identified by monoclonal antibodies
Published 2020-01-01“…We developed and used monoclonal antibodies to characterize the protein target range of omeprazole, stability of omeprazole-bound proteins, and the involvement of cysteines in binding of omeprazole to targets. …”
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Identification of proteins targeted by the thioredoxin superfamily in Plasmodium falciparum.
Published 2009-04-01Get full text
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Binding of omeprazole to protein targets identified by monoclonal antibodies.
Published 2020-01-01“…We developed and used monoclonal antibodies to characterize the protein target range of omeprazole, stability of omeprazole-bound proteins, and the involvement of cysteines in binding of omeprazole to targets. …”
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Protein-Targeted Degradation Agents Based on Natural Products
Published 2022-12-01“…It is noteworthy that natural products and their derivatives, as important components of PROTACs and molecular glues, play an important role in the development of protein-targeting drugs. Hence, this review summarized the protein-targeted degradation agents based on natural products, such as PROTACs and molecular glues. …”
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Design of Protein Segments and Peptides for Binding to Protein Targets
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High-throughput structural characterisation of therapeutic protein targets.
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High-throughput structural characterisation of therapeutic protein targets
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Electrophilic affibodies forming covalent bonds to protein targets.
Published 2009“…Here, we investigate the effect on recognition of protein targets of placing an unnatural electrophile adjacent to the target binding site. …”
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Global analysis of small molecule binding to related protein targets.
Published 2012-01-01Get full text
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