The Mouse Cytomegalovirus Gene m42 Targets Surface Expression of the Protein Tyrosine Phosphatase CD45 in Infected Macrophages. by Nadine Thiel, Kirsten A Keyser, Niels A W Lemmermann, Jennifer D Oduro, Karen Wagner, Carina Elsner, Anne Halenius, Tihana Lenac Roviš, Melanie M Brinkmann, Stipan Jonjić, Luka Cicin-Sain, Martin Messerle

“…The receptor-like protein tyrosine phosphatase CD45 is expressed on the surface of cells of hematopoietic origin and has a pivotal role for the function of these cells in the immune response. …”
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Protein tyrosine phosphatase nonreceptor 13 (PTPN13) is targeted by human papillomavirus 16 E6 in cervical epithelium by Bossler A, Strand G, Haugen T, Turek L, Lace M, Goodheart M, De Geest K, Hoover A, Nowicki P, Klingelhutz A, Lee J

Identification of protein tyrosine phosphatase receptor gamma extracellular domain (sPTPRG) as a natural soluble protein in plasma. by Elisabetta Moratti, Marzia Vezzalini, Luisa Tomasello, Davide Giavarina, Claudio Sorio

“…PTPRG is a widely expressed protein tyrosine phosphatase present in various isoforms. Peptides from its extracellular domain have been detected in plasma by proteomic techniques. …”
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Virtual Screening and Biological Evaluation of Novel Low Molecular Weight Protein Tyrosine Phosphatase Inhibitor for the Treatment of Insulin Resistance by Feng B, Dong X, Liu Z, Zhang J, Liu H, Xu Y

Subjects: “…low molecular weight protein tyrosine phosphatase…”
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Protein tyrosine phosphatase-induced hyperactivity is a conserved strategy of a subset of baculoviruses to manipulate lepidopteran host behavior. by Stineke van Houte, Vera I D Ros, Tom G Mastenbroek, Nadia J Vendrig, Kelli Hoover, Jeroen Spitzen, Monique M van Oers

“…Furthermore, we identify the viral protein tyrosine phosphatase (ptp) gene as a key player in the induction of hyperactivity in larvae, and show that mutating the catalytic site of the encoded phosphatase enzyme prevents this induced behavior. …”
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Regulation of Phosphoinositide Levels in the Retina by Protein Tyrosine Phosphatase 1B and Growth Factor Receptor-Bound Protein 14 by Raju V. S. Rajala, Austin McCauley, Rahul Rajala, Kenneth Teel, Ammaji Rajala

“…The length of a cellular response depends on the interplay between activating protein kinases and deactivating protein phosphatases. Protein tyrosine phosphatase 1B (PTP1B) and growth factor receptor-bound protein 14 (Grb14) are negative regulators of receptor tyrosine kinases. …”
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Neural conditional ablation of the protein tyrosine phosphatase receptor Delta PTPRD impairs gliogenesis in the developing mouse brain cortex by Francisca Cornejo, Nayhara Franchini, Bastián I. Cortés, Bastián I. Cortés, Daniela Elgueta, Gonzalo I. Cancino

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Expression of oxidized protein tyrosine phosphatase and γH2AX predicts poor survival of gastric carcinoma patients by Usama Khamis Hussein, Ho Sung Park, Jun Sang Bae, Kyoung Min Kim, Yun Jo Chong, Chan Young Kim, Keun Sang Kwon, Myoung Ja Chung, Ho Lee, Myoung Jae Kang, Woo Sung Moon, Kyu Yun Jang

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Role of receptor protein tyrosine phosphatase alpha (RPTPalpha) and tyrosine phosphorylation in the serotonergic inhibition of voltage-dependent potassium channels. by Imbrici, P, Tucker, S, D'Adamo, M, Pessia, M

“…Furthermore, we demonstrate that receptor protein tyrosine phosphatase alpha (RPTPalpha), a receptor protein tyrosine phosphatase, co-ordinates the inhibition process mediated via 5-HT2C receptors. …”

Protein tyrosine phosphatase 1B deficiency ameliorates murine experimental colitis via the expansion of myeloid-derived suppressor cells. by Jing Zhang, Bing Wang, Wen Zhang, Yao Wei, Zhen Bian, Chen-Yu Zhang, Limin Li, Ke Zen

“…Protein tyrosine phosphatase 1B (PTP1B) is a key molecule in modulating low-degree inflammatory conditions such as diabetes. …”
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α-Glucosidase and Protein Tyrosine Phosphatase 1B Inhibitory Activity of Plastoquinones from Marine Brown Alga Sargassum serratifolium by Md. Yousof Ali, Da Hye Kim, Su Hui Seong, Hyeung-Rak Kim, Hyun Ah Jung, Jae Sue Choi

“…This study aims to investigate the anti-diabetic activity of S. serratifolium and its major constituents through inhibition of protein tyrosine phosphatase 1B (PTP1B), α-glucosidase, and ONOO−-mediated albumin nitration. …”
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Role of protein tyrosine phosphatase non-receptor type 7 in the regulation of TNF-α production in RAW 264.7 macrophages. by Huiyun Seo, In-Seon Lee, Jae Eun Park, Sung Goo Park, Do Hee Lee, Byoung Chul Park, Sayeon Cho

“…Protein tyrosine phosphatases play key roles in a diverse range of cellular processes such as differentiation, cell proliferation, apoptosis, immunological signaling, and cytoskeletal function. …”
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Isoquinoline Alkaloids as Protein Tyrosine Phosphatase Inhibitors from a Deep-Sea-Derived Fungus <em>Aspergillus puniceus</em> by Cheng-Mei Liu, Fei-Hua Yao, Xin-Hua Lu, Xue-Xia Zhang, Lian-Xiang Luo, Xiao Liang, Shu-Hua Qi

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Clinical Characteristics and Prognosis of Acute Myeloid Leukemia Patients with Protein Tyrosine Phosphatase Non-Receptor Type 11 Gene Mutation by Huang R, Zhang YT, Lin Y, Pang RL, Yang Z, Zhao WH

“…Rui Huang,&ast; Yi-Ting Zhang,&ast; Yu Lin, Ru-Li Pang, Zhi Yang, Wei-Hua Zhao Department of Hematology, the First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi Zhuang Autonomous Region, 530021, People’s Republic of China&ast;These authors contributed equally to this workCorrespondence: Wei-Hua Zhao, Department of Hematology, the First Affiliated Hospital of Guangxi Medical University, Shuang-Yong Road 6, Nanning, Guangxi Zhuang Autonomous Region, People’s Republic of China, Tel +86-771-5356746, Fax +86-771-5352681, Email zhaowh21@163.comObjective: The purpose of our study was to investigate the clinical characteristics, molecular biological characteristics and prognosis of acute myeloid leukemia (AML) patients with protein tyrosine phosphatase non-receptor type 11 (PTPN11) gene mutation.Methods: The clinical data of 30 newly diagnosed adult AML patients with PTPN11 gene mutation were analyzed retrospectively. …”
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Assessment of protein tyrosine phosphatases number 22 polymorphism prevalence among rheumatoid arthritis patients: A study on Iranian patients by Mansour Salesi, Golshan Taghipour Boroujeni, Mansoor Salehi, Hadi Karimzadeh

“…Background: It has been proposed that Trp (620) allotype of protein tyrosine phosphatases number 22 (PTPN22) gene can intensify the susceptibility to rheumatoid arthritis (RA) and other autoimmune diseases. …”
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The translation attenuating arginine-rich sequence in the extended signal peptide of the protein-tyrosine phosphatase PTPRJ/DEP1 is conserved in mammals. by Luchezar Karagyozov, Petar N Grozdanov, Frank-D Böhmer

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Terminalin from African Mango (<i>Irvingia gabonensis</i>) Stimulates Glucose Uptake through Inhibition of Protein Tyrosine Phosphatases by Sun-Young Yoon, Jinsoo Kim, Bum Soo Lee, Su Cheol Baek, Sang J. Chung, Ki Hyun Kim

Subjects: “…protein tyrosine phosphatases (PTPs)…”
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Tumor derived mutations of protein tyrosine phosphatase receptor type k affect its function and alter sensitivity to chemotherapeutics in glioma. by Supreet Agarwal, Maha S Al-Keilani, Mohammad A Y Alqudah, Zita A Sibenaller, Timothy C Ryken, Mahfoud Assem

“…Using mapping arrays to screen for genomic alterations in gliomas, we recently identified alterations of the protein tyrosine phosphatase receptor type kappa gene (PTPRK) that correlate to patient outcomes. …”
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In silico extension on the antidiabetic potential of Euonymus laxiflorus natural compounds onto the inhibitability against protein tyrosine phosphatase 1B by Thanh Q. Bui, Vinh Phu Nguyen, Thi Thanh Hai Nguyen, Tu Quy Phan, Nguyen Thi Ai Nhung

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1H-2,3-Dihydroperimidine Derivatives: A New Class of Potent Protein Tyrosine Phosphatase 1B Inhibitors by Wen-Long Wang, Dong-Lin Yang, Li-Xin Gao, Chun-Lan Tang, Wei-Ping Ma, Hui-Hua Ye, Si-Qi Zhang, Ya-Nan Zhao, Hao-Jie Xu, Zhao Hu, Xia Chen, Wen-Hua Fan, Hai-Jun Chen, Jing-Ya Li, Fa-Jun Nan, Jia Li, Bainian Feng

“…A series of 1H-2,3-dihydroperimidine derivatives was designed, synthesized, and evaluated as a new class of inhibitors of protein tyrosine phosphatase 1B (PTP1B) with IC50 values in the micromolar range. …”
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