Roles of the PTP61F Gene in Regulating Energy Metabolism of Tribolium castaneum (Coleoptera: Tenebrionidae) by Kang-Kang Xu, Bi-Ying Pan, Yuan-Yuan Wang, Qian-Qian Ren, Can Li

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LAR Receptor Tyrosine Phosphatase Family in Healthy and Diseased Brain by Francisca Cornejo, Bastián I. Cortés, Greg M. Findlay, Gonzalo I. Cancino, Gonzalo I. Cancino

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The Role of Inflammation in Diabetic Retinopathy by John V. Forrester, Lucia Kuffova, Lucia Kuffova, Mirela Delibegovic

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Artificial Intelligence-Based Computational Screening and Functional Assays Identify Candidate Small Molecule Antagonists of PTPmu-Dependent Adhesion by Kathleen Molyneaux, Christian Laggner, Susann M. Brady-Kalnay

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Insulin regulates POMC neuronal plasticity to control glucose metabolism by Garron T Dodd, Natalie J Michael, Robert S Lee-Young, Salvatore P Mangiafico, Jack T Pryor, Astrid C Munder, Stephanie E Simonds, Jens Claus Brüning, Zhong-Yin Zhang, Michael A Cowley, Sofianos Andrikopoulos, Tamas L Horvath, David Spanswick, Tony Tiganis

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PTPRZ1 regulates calmodulin phosphorylation and tumor progression in small-cell lung carcinoma by Makinoshima Hideki, Ishii Genichiro, Kojima Motohiro, Fujii Satoshi, Higuchi Youichi, Kuwata Takeshi, Ochiai Atsushi

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Evidence of Insulin-Sensitizing and Mimetic Activity of the Sesquiterpene Quinone Avarone, a Protein Tyrosine Phosphatase 1B and Aldose Reductase Dual Targeting Agent from the Marine Sponge <i>Dysidea avara</i> by Marcello Casertano, Massimo Genovese, Alice Santi, Erica Pranzini, Francesco Balestri, Lucia Piazza, Antonella Del Corso, Sibel Avunduk, Concetta Imperatore, Marialuisa Menna, Paolo Paoli

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Myeloid protein tyrosine phosphatase 1B (PTP1B) deficiency protects against atherosclerotic plaque formation in the ApoE−/− mouse model of atherosclerosis with alterations in IL10/AMPKα pathway by D. Thompson, N. Morrice, L. Grant, S. Le Sommer, K. Ziegler, P. Whitfield, N. Mody, H.M. Wilson, M. Delibegović

“…We hypothesized that inhibiting the activity of protein tyrosine phosphatase 1B (PTP1B), the major negative regulator of the IR, specifically in macrophages, would have beneficial anti-inflammatory effects and lead to protection against atherosclerosis and CVD. …”
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Inhibition of Protein-Tyrosine Phosphatase PTP1B and LMPTP Promotes Palmitate/Oleate-Challenged HepG2 Cell Survival by Reducing Lipoapoptosis, Improving Mitochondrial Dynamics and Mitigating Oxidative and Endoplasmic Reticulum Stress by Lynda Bourebaba, Jacek Łyczko, Michalina Alicka, Nabila Bourebaba, Antoni Szumny, Andrzej M. Fal, Krzysztof Marycz

“…The severity of NAFLD correlates with the degree of hepatocyte lipoapoptosis. Protein–tyrosine phosphatases (PTP) including PTP1B and Low molecular weight PTP (LMPTP), are negative regulators of the insulin signaling pathway and are considered a promising therapeutic target in the treatment of diabetes. …”
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Expression and Clinical Significance of SHP2 in the Tumor Tissues of Smokers with Lung Cancer by Xuemei ZHAN, Hongyan DONG, Chongwei SUN, Lili LIU, Dan WANG, Zhiyong WEI

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Differential contribution of canonical and noncanonical NLGN3 pathways to early social development and memory performance by Lin-Yu Li, Ayako Imai, Hironori Izumi, Ran Inoue, Yumie Koshidaka, Keizo Takao, Hisashi Mori, Tomoyuki Yoshida

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Final Exon Frameshift Biallelic <i>PTPN23</i> Variants Are Associated with Microcephalic Complex Hereditary Spastic Paraplegia by Reham Khalaf-Nazzal, James Fasham, Nishanka Ubeyratna, David J. Evans, Joseph S. Leslie, Thomas T. Warner, Fida’ Al-Hijawi, Shurouq Alshaer, Wisam Baker, Peter D. Turnpenny, Emma L. Baple, Andrew H. Crosby

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Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP) by Lester J Lambert, Stefan Grotegut, Maria Celeridad, Palak Gosalia, Laurent JS De Backer, Andrey A Bobkov, Sumeet Salaniwal, Thomas DY Chung, Fu-Yue Zeng, Ian Pass, Paul J Lombroso, Nicholas DP Cosford, Lutz Tautz

Subjects: “…protein tyrosine phosphatase…”
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Cytoneme-like protrusion formation induced by LAR is promoted by receptor dimerization by Mai Quynh Nguyen, Manabu Taniguchi, Misato Yasumura, Tokuichi Iguchi, Makoto Sato

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Potential of Myrtus communis Linn. as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS and NMR for identification of a... by Chao Liang, Dan Staerk, Kenneth T. Kongstad

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Discovery of a SHP2 Degrader with In Vivo Anti-Tumor Activity by Jinmin Miao, Yunpeng Bai, Yiming Miao, Zihan Qu, Jiajun Dong, Ruo-Yu Zhang, Devesh Aggarwal, Brenson A. Jassim, Quyen Nguyen, Zhong-Yin Zhang

Subjects: “…protein tyrosine phosphatase…”
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Brazilian insulin plant as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antidiabetic... by Rita de Cássia Lemos Lima, Lucília Kato, Kenneth Thermann Kongstad, Dan Staerk

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Can Allostery Be a Key Strategy for Targeting PTP1B in Drug Discovery? A Lesson from Trodusquemine by Rosanna Maccari, Rosaria Ottanà

Subjects: “…protein tyrosine phosphatase 1B…”
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Papaverinol-<i>N</i>-Oxide: A Microbial Biotransformation Product of Papaverine with Potential Antidiabetic and Antiobesity Activity Unveiled with In Silico Screening by Duaa Eliwa, Amal Kabbash, Mona El-Aasr, Haytham O. Tawfik, Gaber El-Saber Batiha, Mohamed H. Mahmoud, Michel De Waard, Wagdy M. Eldehna, Abdel-Rahim S. Ibrahim

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Glucose Uptake Activities of Bis (2, 3-Dibromo-4, 5-Dihydroxybenzyl) Ether, a Novel Marine Natural Product from Red Alga Odonthaliacorymbifera with Protein Tyrosine Phosphatase 1B Inhibition, In Vitro and In Vivo. by Feng Xu, Fang Wang, Zhenhong Wang, Wenshan Lv, Wei Wang, Yangang Wang

“…BACKGROUND AND AIMS:Protein tyrosine phosphatase 1B (PTP1B) is a novel therapeutic target for type-2 diabetes, which negatively regulates the insulin signaling transduction. …”
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