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Downregulation of Protein Tyrosine Phosphatase Receptor Type R Accounts for the Progression of Hirschsprung Disease
Published 2019-04-01Subjects: Get full text
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62
Social Memory and Social Patterns Alterations in the Absence of STriatal-Enriched Protein Tyrosine Phosphatase
Published 2019-01-01“…STriatal-Enriched protein tyrosine Phosphatase (STEP) is a neural-specific protein that opposes the development of synaptic strengthening and whose levels are altered in several neurodegenerative and psychiatric disorders. …”
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63
Receptor protein tyrosine phosphatase delta is not essential for synapse maintenance or transmission at hippocampal synapses
Published 2020-06-01“…Abstract Members of the leukocyte common antigen-related receptor protein tyrosine phosphatase (LAR-RPTP) family, comprising PTPσ, PTPδ and LAR, are key hubs for presynaptic assembly and differentiation in vertebrate neurons. …”
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64
Role of protein tyrosine phosphatase receptor type M in epithelial ovarian cancer progression
Published 2023-07-01Subjects: “…Receptor-like protein tyrosine phosphatases…”
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65
Use of an Anaerobic Chamber Environment for the Assay of Endogenous Cellular Protein-Tyrosine Phosphatase Activities
Published 2002-01-01Subjects: Get full text
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66
Phloridzin Acts as an Inhibitor of Protein-Tyrosine Phosphatase MEG2 Relevant to Insulin Resistance
Published 2021-03-01Subjects: “…protein tyrosine phosphatases (PTPs)…”
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67
Stearic Acid Serves as a Potent Inhibitor of Protein Tyrosine Phosphatase 1B
Published 2013-11-01Subjects: Get full text
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68
Pan-cancer analyses of classical protein tyrosine phosphatases and phosphatase-targeted therapy in cancer
Published 2022-10-01“…Protein tyrosine phosphatases function in dephosphorylating target proteins to regulate signaling pathways that control a broad spectrum of fundamental physiological and pathological processes. …”
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Evaluation of the Hypoglycemic Activity of Morchella conica by Targeting Protein Tyrosine Phosphatase 1B
Published 2021-05-01Subjects: “…protein tyrosine phosphatase 1B activity…”
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71
High expression of protein tyrosine phosphatase receptor S (PTPRS) is an independent prognostic marker for cholangiocarcinoma
Published 2022-08-01“…The proteome results showed that protein tyrosine phosphatase receptor S (PTPRS) had the highest potential candidate. …”
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72
The crystal structure of human receptor protein tyrosine phosphatase kappa phosphatase domain 1.
Published 2006“…The receptor-type protein tyrosine phosphatases (RPTPs) are integral membrane proteins composed of extracellular adhesion molecule-like domains, a single transmembrane domain, and a cytoplasmic domain. …”
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73
Methyl Syringate Stimulates Glucose Uptake by Inhibiting Protein Tyrosine Phosphatases Relevant to Insulin Resistance
Published 2023-06-01Subjects: “…protein tyrosine phosphatases (PTPs)…”
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74
Analysis of Receptor-Type Protein Tyrosine Phosphatase Extracellular Regions with Insights from AlphaFold
Published 2024-01-01Subjects: “…receptor-type protein tyrosine phosphatases (RPTPs)…”
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75
Structural stability of human protein tyrosine phosphatase ρ catalytic domain: effect of point mutations.
Published 2012-01-01“…Protein tyrosine phosphatase ρ (PTPρ) belongs to the classical receptor type IIB family of protein tyrosine phosphatase, the most frequently mutated tyrosine phosphatase in human cancer. …”
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Dual role of protein tyrosine phosphatase 1B in the progression and reversion of non-alcoholic steatohepatitis
Published 2018-01-01“…Objectives: Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in Western countries. Protein tyrosine phosphatase 1B (PTP1B), a negative modulator of insulin and cytokine signaling, is a therapeutic target for type 2 diabetes and obesity. …”
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Src-homology protein tyrosine phosphatase-1 agonist, SC-43, reduces liver fibrosis
Published 2017-05-01“…Abstract This study aimed to investigate the role of src-homology protein tyrosine phosphatase-1 (SHP-1)–signal transducer and activator of transcription 3 (STAT3) pathway in liver fibrogenesis and the anti-fibrotic effect of SHP-1 agonist. …”
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79
Novel Mixed-Type Inhibitors of Protein Tyrosine Phosphatase 1B. Kinetic and Computational Studies
Published 2017-12-01Subjects: “…protein tyrosine phosphatase 1B…”
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80
Targeting Receptor-Type Protein Tyrosine Phosphatases with Biotherapeutics: Is Outside-in Better than Inside-Out?
Published 2018-03-01“…Protein tyrosine phosphatases (PTPs), of the receptor and non-receptor classes, are key signaling molecules that play critical roles in cellular regulation underlying diverse physiological events. …”
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Article