Showing 1 - 20 results of 1,173 for search '"Protein tyrosine phosphatase"', query time: 0.69s Refine Results
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    The Roles of Protein Tyrosine Phosphatases in Hepatocellular Carcinoma by Yide Huang, Yafei Zhang, Lilin Ge, Yao Lin, Hang Fai Kwok

    Published 2018-03-01
    Subjects: “…protein-tyrosine phosphatase inhibitors…”
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    Article
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    Protein tyrosine phosphatases in skeletal development and diseases by Huiliang Yang, Lijun Wang, Christian Shigley, Wentian Yang

    Published 2022-01-01
    “…Under physiological conditions, PYP is balanced by the coordinated action of PTKs and protein tyrosine phosphatases (PTPs). Dysregulation of PYP can cause genetic, metabolic, developmental, and oncogenic skeletal diseases. …”
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    Article
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    Protein tyrosine phosphatases: structure-function relationships. by Tabernero, L, Aricescu, A, Jones, E, Szedlacsek, SE

    Published 2008
    “…Structural analysis of protein tyrosine phosphatases (PTPs) has expanded considerably in the last several years, producing more than 200 structures in this class of enzymes (from 35 different proteins and their complexes with ligands). …”
    Journal article
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    Targeting Protein Tyrosine Phosphatases to Improve Cancer Immunotherapies by Robert J. Salmond

    Published 2024-01-01
    Subjects: “…protein tyrosine phosphatase (non-receptor type)…”
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    Article
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    The role of receptor‐type protein tyrosine phosphatases in cancer by Zhengyuan Lv, Tianming Wang, Xin Cao, Mengting Sun, Yuan Qu

    Published 2023-03-01
    “…Abstract Receptor‐type protein tyrosine phosphatases (RPTPs), Class I protein tyrosine phosphatases, are involved in human tumor cell proliferation, apoptosis, migration, and invasion through reversible phosphorylation of tyrosine residues. …”
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    Article
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    Large-scale structural analysis of protein tyrosine phosphatases by Barr, A, Knapp, S

    Published 2010
    “…Protein tyrosine phosphatases (PTPs) are essential regulators of signal transduction pathways, and control, together with protein tyrosine kinases (PTKs), the reversible phosphorylation of tyrosine residues. …”
    Journal article
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    Modulation of catalytic activity in multi-domain protein tyrosine phosphatases. by Lalima L Madan, S Veeranna, Khader Shameer, Chilamakuri C S Reddy, R Sowdhamini, B Gopal

    Published 2011-01-01
    “…Signaling mechanisms involving protein tyrosine phosphatases govern several cellular and developmental processes. …”
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    Article
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    The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis by Hideaki Tomita, Francisca Cornejo, Begoña Aranda-Pino, Cameron L. Woodard, Constanza C. Rioseco, Benjamin G. Neel, Alejandra R. Alvarez, David R. Kaplan, Freda D. Miller, Gonzalo I. Cancino

    Published 2020-01-01
    “…Summary: PTPRD is a receptor protein tyrosine phosphatase that is genetically associated with neurodevelopmental disorders. …”
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    Dimerization of Receptor Protein-Tyrosine Phosphatase alpha in living cells by Gadella Theodorus WJ, Overvoorde John, Jiang Guoqiang, Blanchetot Christophe, Tertoolen Leon GJ, Hunter Tony, Hertog Jeroen den

    Published 2001-06-01
    “…Structural, functional and biochemical studies suggested that the enzymatic counterparts of RPTKs, the receptor protein-tyrosine phosphatases (RPTPs), are inhibited by dimerization, but whether RPTPs actually dimerize in living cells remained to be determined.…”
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    The mechanism of allosteric inhibition of protein tyrosine phosphatase 1B. by Shuai Li, Jingmiao Zhang, Shaoyong Lu, Wenkang Huang, Lv Geng, Qiancheng Shen, Jian Zhang

    Published 2014-01-01
    “…As the prototypical member of the PTP family, protein tyrosine phosphatase 1B (PTP1B) is an attractive target for therapeutic interventions in type 2 diabetes. …”
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