Biological insights from 108 schizophrenia-associated genetic loci. by Schizophrenia Working Group of the Psychiatric Genomics Consortium

Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson's disease. by Bryois, J, Skene, NG, Hansen, TF, Kogelman, LJA, Watson, HJ, Liu, Z, Eating Disorders Working Group of the Psychiatric Genomics Consortium, International Headache Genetics Consortium, 23andMe Research Team, Brueggeman, L, Breen, G, Bulik, CM, Arenas, E, Hjerling-Leffler, J, Sullivan, PF

Polygenic transmission disequilibrium confirms that common and rare variation act additively to create risk for autism spectrum disorders. by Walters, RK, Kosmicki, JA, Grove, J, Samocha, KE, Goldstein, JI, Okbay, A, Bybjerg-Grauholm, J, Werge, T, Hougaard, DM, Taylor, J, iPSYCH-Broad Autism Group, Psychiatric Genomics Consortium Autism Group, Skuse, D, Devlin, B, Anney, R, Sanders, SJ, Bishop, S, Mortensen, PB, Børglum, AD, Smith, GD, Daly, MJ, Robinson, EB

Evidence for genetic overlap between schizophrenia and age at first birth in women by Tropf, F, Mills, M, Barban, N, Mehta, D, Gratten, J, Bakshi, A, Zhu, Z, Bacanu, S, Hermani, G, Magnusson, P, Esko, T, Metspalu, A, Snieder, H, Mowry, B, Kendler, K, Yang, J, Visscher, P, McGrath, J, Wray, N, Lee, S, Schizophrenia Working Group of the Psychiatric Genomics Consortium, LifeLines Cohort Study, TwinsUK

Hair cortisol in twins: Heritability and genetic overlap with psychological variables and stress-system genes by Rietschel, L, Streit, F, Zhu, G, McAloney, K, Frank, J, Couvy-Duchesne, B, Witt, SH, Binz, TM, McGrath, J, Hickie, IB, Hansell, NK, Wright, MJ, Gillespie, NA, Forstner, AJ, Schulze, TG, Wüst, S, Nöthen, MM, Baumgartner, MR, Walker, BR, Crawford, AA, Colodro-Conde, L, Medland, SE, Martin, NG, Rietschel, M, Mahajan, A, Lindgren, C, Morris, AP, CORtisolNETwork (CORNET) Consortium, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium (PGC)

Analysis of Genetically Regulated Gene Expression Identifies a Prefrontal PTSD Gene, SNRNP35, Specific to Military Cohorts by Huckins, Laura M., Chatzinakos, Chris, Breen, Michael S., Hartmann, Jakob, Klengel, Torsten, da Silva Almeida, Ana C., Dobbyn, Amanda, Girdhar, Kiran, Hoffman, Gabriel E., Klengel, Claudia, Logue, Mark W., Lori, Adriana, Maihofer, Adam X., Morrison, Filomene G., Nguyen, Hoang T., Park, YongJin, Ruderfer, Douglas, Sloofman, Laura G., van Rooij, Sanne J.H., Baker, Dewleen G., Chen, Chia-Yen, Cox, Nancy, Duncan, Laramie E., Geyer, Mark A., Glatt, Stephen J., Im, Hae Kyung, Risbrough, Victoria B., Smoller, Jordan W., Stein, Dan J., Yehuda, Rachel, Liberzon, Israel, Koenen, Karestan C., Jovanovic, Tanja, Kellis, Manolis, Miller, Mark W., Bacanu, Silviu-Alin, Nievergelt, Caroline M., Buxbaum, Joseph D., Sklar, Pamela, Ressler, Kerry J., Stahl, Eli A., Daskalakis, Nikolaos P., PTSD Working Group of Psychiatric Genomics Consortium

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Use of schizophrenia and bipolar disorder polygenic risk scores to identify psychotic disorders by Calafato, MS, Thygesen, JH, Ranlund, S, Zartaloudi, E, Cahn, W, Crespo-Facorro, B, Díez-Revuelta, Á, Di Forti, M, Genetic Risk And Outcome Of Psychosis (Group) Consortium, Hall, M-H, Iyegbe, C, Jablensky, A, Kahn, R, Kalaydjieva, L, Kravariti, E, Lin, K, McDonald, C, McIntosh, AM, McQuillin, A, Psychosis Endophenotypes International Consortium (PEIC), Picchioni, M, Rujescu, D, Shaikh, M, Toulopoulou, T, Os, JV, Vassos, E, Walshe, M, Powell, J, Lewis, CM, Murray, RM, Bramon, E, Wellcome Trust Case Control Consortium 2 (WTCCC2)

“…<strong>Method</strong> Using the latest Psychiatric Genomics Consortium data, we calculated schizophrenia and bipolar disorder polygenic risk scores for 1168 people with psychosis, 552 unaffected relatives and 1472 controls. …”

Are genetic risk factors for psychosis also associated with dimension-specific psychotic experiences in adolescence? by Sieradzka, D, Power, R, Freeman, D, Cardno, A, McGuire, P, Plomin, R, Meaburn, E, Dudbridge, F, Ronald, A

“…Polygenic risk scores were calculated using estimates of the log of odds ratios from the Psychiatric Genomics Consortium GWAS stage-1 mega-analysis of schizophrenia and bipolar disorder. …”

Investigating causal relationships between genetically determined increased risk of attention-deficit/hyperactivity disorder (ADHD) and atopic dermatitis (AD): A Mendelian randomiz... by Ng, W, Loh, Marie, Yew, Yik Weng

“…Two-sample bi-directional MR was conducted to elucidate potential causal relationships between genetically increased risk of AD and ADHD, using the largest and most recent genome-wide association study datasets for AD and ADHD-EArly Genetics & Lifecourse Epidemiology AD consortium (21 399 cases and 95 464 controls) and Psychiatric Genomics Consortium (20 183 cases and 35 191 controls). …”
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The genetic architecture of depression in individuals of East Asian ancestry: a genome-wide association study by Giannakopoulou, O, Lin, K, Meng, X, Millwood, I, Chen, Y, Chen, Z, Walters, RG

Meta-analysis of GWAS of over 16,000 individuals with autism spectrum disorder highlights a novel locus at 10q24.32 and a significant overlap with schizophrenia by Anney, RJL, Ripke, S, Anttila, V, Grove, J, Holmans, P, Huang, H, Klei, L, Lee, PH, Medland, SE, Neale, B, Robinson, E, Weiss, LA, Zwaigenbaum, L, Yu, TW, Wittemeyer, K, Willsey, AJ, Wijsman, EM, Werge, T, Wassink, TH, Waltes, R, Walsh, CA, Wallace, S, Vorstman, JAS, Vieland, VJ, Vicente, AM, vanEngeland, H, Tsang, K, Thompson, AP, Szatmari, P, Svantesson, O, Steinberg, S, Stefansson, K, Stefansson, H, State, MW, Soorya, L, Silagadze, T, Scherer, SW, Schellenberg, GD, Sandin, S, Sanders, SJ, Saemundsen, E, Rouleau, GA, Roge, B, Roeder, K, Roberts, W, Reichert, J, Reichenberg, A, Rehnstrom, K, Regan, R, Poustka, F, Poultney, CS, Piven, J, Pinto, D, Pericak-Vance, MA, Pejovic-Milovancevic, M, Pedersen, MG, Pedersen, CB, Paterson, AD, Parr, JR, Pagnamenta, AT, Oliveira, G, Nurnberger, JI, Nordentoft, M, Murtha, MT, Mouga, S, Mortensen, PB, Mors, O, Morrow, EM, Moreno-De-Luca, D, Monaco, AP, Minshew, N, Merikangas, A, McMahon, WM, McGrew, SG, Mattheisen, M, Martsenkovsky, I, Martin, DM, Mane, SM, Magnusson, P, Magalhaes, T, Maestrini, E, Lowe, JK, Lord, C, Levitt, P, LeseMartin, C, Ledbetter, DH, Leboyer, M, LeCouteur, AS, Ladd-Acosta, C, Kolevzon, A, Klauck, SM, Jacob, S, Iliadou, B, Hultman, CM, Hougaard, DM, Hertz-Picciotto, I, Hendren, R, Hansen, CS, Haines, JL, Guter, SJ, Grice, DE, Green, JM, Green, A, Goldberg, AP, Gillberg, C, Gilbert, J, Gallagher, L, Freitag, CM, Fombonne, E, Folstein, SE, Fernandez, B, Fallin, MD, Ercan-Sencicek, AG, Ennis, S, Duque, F, Duketis, E, Delorme, R, DeRubeis, S, DeJonge, MV, Dawson, G, Cuccaro, ML, Correia, CT, Conroy, J, Conceicao, IC, Chiocchetti, AG, Celestino-Soper, PBS, Casey, J, Cantor, RM, Cafe, C, Bybjerg-Grauholm, J, Brennan, S, Bourgeron, T, Bolton, PF, Boelte, S, Bolshakova, N, Betancur, C, Bernier, R, Beaudet, AL, Battaglia, A, Bal, VH, Baird, G, Bailey, AJ, Baekvad-Hansen, M, Bader, JS, Bacchelli, E, Anagnostou, E, Amaral, D, Almeida, J, Borglum, AD, Buxbaum, JD, Chakravarti, A, Cook, EH, Coon, H, Geschwind, DH, Gill, M, Hakonarson, H, Hallmayer, J, Palotie, A, Santangelo, S, Sutcliffe, JS, Arking, DE, Devlin, B, Daly, MJ

“…We further combined these Psychiatric Genomics Consortium (PGC) ASD GWAS data with the recent PGC schizophrenia GWAS to identify additional regions which may be important in a common neurodevelopmental phenotype and identified 12 novel GWS loci. …”