The effect of smartphone-based monitoring and treatment including clinical feedback versus smartphone-based monitoring without clinical feedback in bipolar disorder: the SmartBipol... by Maria Faurholt-Jepsen, Natacha Blauenfeldt Kyster, Malene Schwarz Dyreholt, Ellen Margrethe Christensen, Pernille Bondo-Kozuch, Anna Skovgaard Lerche, Birte Smidt, Ulla Knorr, Kim Brøndmark, Anne-Marie Bangsgaard Cardoso, Anja Mathiesen, Rene Sjælland, Henrik Nørbak-Emig, Lotte Linnemann Sponsor, Darius Mardosas, Ida Palmblad Sarauw-Nielsen, Jens Drachmann Bukh, Trine Vøgg Heller, Mads Frost, Nanna Iversen, Jakob Eyvind Bardram, Jonas Busk, Maj Vinberg, Lars Vedel Kessing

“…The outcomes are (1) mood instability (primary), (2) quality of life, self-rated depressive symptoms, self-rated manic symptoms, perceived stress, satisfaction with care, cumulated number and duration of psychiatric hospitalizations, and medication (secondary), and (3) smartphone-based measures per month of stress, anxiety, irritability, activity, and sleep as well as the percentage of days with presence of mixed mood, days with adherence to medication and adherence to smartphone-based self-monitoring. …”
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Vox clamantis in deserto: a survey among Italian psychiatrists on defensive medicine and professional liability by Pasquale Scognamiglio, Donato Morena, Nicola Di Fazio, Giuseppe Delogu, Valeria Iniziato, Silvestro La Pia, Pasquale Saviano, Paola Frati, Vittorio Fineschi

“…Specifically, overwhelming pressure on psychiatrists’ duties has been brought by regulatory developments, such as the closure of forensic psychiatric hospitals, with the consequent return of offenders to community-based care, and the mental health consequences of the pandemic. …”
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Preliminary findings on diagnostic validity of the ICD-11 personality disorder scales among Croatian psychiatric patients by N. Jaksic, I. Simunovic Filipcic, M. Sagud, B. Vuksan Cusa, M. Skocic Hanzek, Z. Madzarac, V. Bilic, J. Grubisin, I. Filipcic, M. Copo, Z. Vuksan Cusa, E. Podolski, D. Marcinko

“…Results Statistical comparison of the two clinical groups revealed that the ‘’PD group” was significantly younger, had relatively more female patients and showed a trend towards higher number of psychiatric hospitalizations, whereas there were no group difference in terms of education level, relationship status and treatment length. …”
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Cerebrospinal fluid biomarkers in psychiatric autoimmune encephalitis: a retrospective cohort study by Niels Hansen, Aaron Levin Juhl, Insa Maria Grenzer, Bianca Teegen, Jens Wiltfang, Jens Wiltfang, Jens Wiltfang, Dirk Fitzner

“…BackgroundPsychiatric autoimmune encephalitis (pAE) is a growing field of interest in diagnosis and therapy in psychiatric hospitals and institutions. This study investigates the relevant extent to which there are potential biomarkers in cerebrospinal fluid (CSF) that can differentiate against a cohort with neurodegenerative disease.MethodsWe included in this study a total of 27 patients with possible and definite psychiatric autoimmune encephalitis and compared with a cohort with CSF-based AD (n = 27) different biomarkers in CSF such as lactate, cell count, % lymphocytes, % monocytes, total protein content, albumin, immunoglobulins G (IgG), M (IgM) and A (IgA), CSF/serum albumin ratio, CSF/serum IgG ratio, CSF/serum IgA ratio, intrathecal IgG synthesis, blood–brain barrier disruption, specific antibody synthesis for measles, rubella, herpes simplex virus, varicella zoster virus, Ebstein-Barr virus and cytomegalovirus, total tau protein (t-tau), phosphorylated tau protein 181 (p-tau181), amyloid beta 42 (Aß42), amyloid beta 40 (Aß40) and the amyloid beta 42/ amyloid beta 40 (Aß42/40) ratio.ResultsThe p-tau 181 was elevated above cut-off values in both possible pAE and AD. …”
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Elevated versus irritable mood: is illness severity any different? by J. T. Coelho, A. S. Machado, F. Andrade, A. Vieira, S. Timóteo, A. Silva

“…When compared with those with irritable mood, euphoric patients had 2.765 more odds of having previous psychiatric hospitalizations (x2(1, N = 143) = 4.93; p = 0.026). …”
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Positive and Negative Syndrome Scale (PANSS) predictors of hospitalization during home treatment on 1045 patients with schizophrenia in acute crisis by R. Talisa, A. Sabaté, D. Córcoles, J. Leon, A. Malagón, A. M. González, M. Bellsolà, P. Samos, M. Á. Jerónimo, L. M. Martín, V. Pérez

“… Introduction Several factors related to the risk of requiring psychiatric hospitalization have been described in patients diagnosed with schizophrenia treated with methods other than home treatment. …”
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The quality of mental health care delivered to patients with schizophrenic disorder in the Italian mental health system. The QUADIM project A multi-regional Italian investigation b... by M. Monzio Compagnoni, G. Corrao, L. Allevi, A. Barbato, B. D’Avanzo, F. Carle, A. Saponaro, A. Gaddini, S. Scondotto, L. Ferrara, V. D. Tozzi, T. Di Fiandra, A. Lora

“… Introduction The 1978 Italian reform of psychiatric services initiated the closure of psychiatric hospitals encouraging the development of community mental health. …”
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Key influences in the design and implementation of mental health information systems in Ghana and South Africa by S. Ahuja, T. Mirzoev, C. Lund, A. Ofori-Atta, S. Skeen, A. Kufuor

“…Results Key components of the MHIS intervention involved the introduction of a redesigned patient registration form, entry into computers for analysis every 2 months by clinical managerial staff, and utilization of data in hospital management meetings in three psychiatric hospitals in Ghana; and the introduction of a new set of mental health indicators and related forms and tally sheets at primary care clinics and district hospitals in five districts in the KwaZulu-Natal and Northern Cape provinces in South Africa. …”
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Controversies regarding lithium-associated weight gain: case–control study of real-world drug safety data by Waldemar Greil, Mateo de Bardeci, Bruno Müller-Oerlinghausen, Nadja Nievergelt, Hans Stassen, Gregor Hasler, Andreas Erfurth, Katja Cattapan, Eckart Rüther, Johanna Seifert, Sermin Toto, Stefan Bleich, Georgios Schoretsanitis

“…Methods We conducted a case/non-case pharmacovigilance study using data from the AMSP project (German: “Arzneimittelsicherheit in der Psychiatrie”; i.e., Drug Safety in Psychiatry), which collects data on ADRs from patients treated in psychiatric hospitals in Germany, Austria, and Switzerland. …”
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Long-Term Treatment with Trazodone Once-A-Day (TzOAD) in Patients with MDD: An Observational, Prospective Study by Shrashimirova M, Tyanev I, Cubała WJ, Wichniak A, Vodickova-Borzova C, Ruggieri A, Bonelli A, Lipone P, Comandini A, Cattaneo A

“…Milena Shrashimirova,1,* Ivan Tyanev,2,* Wiesław J Cubała,3,* Adam Wichniak,4,* Claudia Vodickova-Borzova,5,* Alessandro Ruggieri,6,* Annalisa Bonelli,6,* Paola Lipone,6,* Alessandro Comandini,6,* Agnese Cattaneo6,* 1Diagnostic Consultative Center 14, Hospital VITA, Sofia, Bulgaria; 2Multiprofile Hospital for Active Treatment, Medical Clinic, Targovishte, Bulgaria; 3Department of Psychiatry, Medical University of Gdańsk, Gdańsk, Poland; 4Third Department of Psychiatry and Sleep Disorders Center, Institute of Psychiatry and Neurology, Warsaw, Poland; 5Psychiatry and Neurology, Brain-Soultherapy.s.r.o, Kladno, Czech Republic; 6Global Medical Department, Angelini Pharma S.p.A, Rome, Italy*These authors contributed equally to this workCorrespondence: Alessandro Ruggieri, Global Medical Department, Angelini Pharma S.p.A, Viale Amelia 70, Rome, 00181, Italy, Tel +390691045309, Email alessandro.ruggieri@angelinipharma.comPurpose: This was an observational, prospective, single-group, multicentre, international study aimed to describe the clinical response, functional impairment, and quality of life (QoL) of patients suffering from major depressive disorder (MDD) and in treatment with Trazodone Once-A-Day (TzOAD) monotherapy, over a 24-week period.Patients and Methods: A total of 200 patients with a diagnosis of MDD who had been treated with TzOAD monotherapy were enrolled from 26 sites across 3 European countries (Bulgaria, Czech Republic, and Poland), including psychiatric private practices, and outpatient departments from general and psychiatric hospitals. Study assessments were completed by physicians and patients during routine visits within the normal practice of care.Results: Clinical response was assessed by Clinical Global Impressions – Improvement (CGI-I) responders’ percentage at 24 (± 4) weeks. …”
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Effectiveness and Quality of Life with Paliperidone Palmitate 3-Monthly in Comparison with Other Long-Acting Drugs by Di Lorenzo R, Iorio A, Pinelli M, Magarini F, Marchi M, Sacchetti A, Calogero C, Galeazzi GM, Ferri P, Rovesti S, Minarini A

“…At 1-year treatment, we evaluated relapses (psychiatric hospitalizations and urgent consultations), side effects and drop-outs.Results: We did not highlight any statistically significant difference among the three treatments in relapses and scale scores. …”
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Agreement between self-reports and statutory health insurance claims data on healthcare utilization in patients with mental disorders by Tarcyane Barata Garcia, Roman Kliemt, Franziska Claus, Anne Neumann, Bettina Soltmann, Fabian Baum, Julian Schwarz, Enno Swart, Jochen Schmitt, Andrea Pfennig, Dennis Häckl, Ines Weinhold

“…Methods Claims data from six German SHI and self-reports were obtained along with a cost-effectiveness analysis performed as a part of a controlled prospective multicenter cohort study conducted in 18 psychiatric hospitals in Germany (PsychCare), including patients with pre-defined psychiatric disorders. …”
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Does risperidone seem safe in patients with antipsychotic-induced leukoneutropenia? Case report by W. Abid, F. Chérif, H. Trigui, S. Hentati, I. Feki, R. Sallemi, J. Masmoudi

“…This patient had only one psychiatric hospitalization in 2021 where he developed persistent leuko-neutropenia. …”
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Sustainability in Dutch and Flemish mental healthcare: A descriptive and comparative study by K. Van Den Broeck, K. Catthoor, J. Luykx, M. De Hert, P. Niemegeers, H. Peeters, W. Krudop, J. Detraux

“…Objectives To evaluate the state of sustainability in Dutch and Flemish mental health institutions (including psychiatric hospitals, rehabilitation centers, and community mental health centers) and assess whether certain differences can be found in the climate policies of these institutions between both regions. …”
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Factors associated with prolonged on-scene time in ambulance transportation among patients with minor diseases or injuries in Japan: a population-based observational study by Keiko Ueno, Chie Teramoto, Daisuke Nishioka, Shiho Kino, Hiroyuki Sawatari, Kazuaki Tanabe

“…To improve community EMS, we should reconsider how to intervene with potentially modifiable factors, such as EMS personnel performance, the impact of the presence of allied services, hospital patient acceptance systems, and cooperation between general emergency and psychiatric hospitals.…”
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Chronic kidney disease incidences in Thai outpatients diagnosed with psychiatric illnesses receiving lithium maintenance therapy: a university hospital-based study by Jarurin Pitanupong, Chavisa Jittpratoom, Kanthee Anantapong

“…When comparing outpatients who had received lithium maintenance therapy and developed chronic kidney disease with those who did not develop chronic kidney disease, this study identified that most of the group with chronic kidney disease had a lithium maintenance therapy for more than ten years, had an older age onset of lithium therapy, reported history of psychiatric hospitalization and lithium intoxication, and presented with physical illness. …”
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Telehealth-Based Psychoeducation for Caregivers: The Family Intervention in Recent-Onset Schizophrenia Treatment Study by Kim T Mueser, Eric D Achtyes, Jagadish Gogate, Branislav Mancevski, Edward Kim, H Lynn Starr

“…The major TF events (ie, psychiatric hospitalization or intervention, arrest or incarceration, and suicide attempts) were assessed at 3, 6, and 12 months after baseline. …”
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Treatment Interruptions and Telemedicine Utilization in Serious Mental Illness: Retrospective Longitudinal Claims Analysis by Marcy Ainslie, Mary F Brunette, Michelle Capozzoli

“… BackgroundAvoiding interruptions and dropout in outpatient care can prevent mental illness symptom exacerbation and costly crisis services, such as emergency room visits and inpatient psychiatric hospitalization. During the COVID-19 pandemic, to attempt to maintain care continuity, telemedicine services were increasingly utilized, despite the lack of data on efficacy in patients with serious mental illness. …”
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Drugs and high hospitalization rate: are they related? by I. M. Figueiredo, I. Cargaleiro, M. Nascimento

“…Objectives Our goal was to analyze if substance use is associated with higher psychiatric hospitalization rates. Methods An independent-samples t-test was run to determine if there were more hospitalizations among patients with substance use. …”
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Prescribing Trends for the Same Patients with Schizophrenia Over 20 Years by Yasui-Furukori N, Kawamata Y, Sasaki T, Yokoyama S, Okayasu H, Shinozaki M, Takeuchi Y, Sato A, Ishikawa T, Komahashi-Sasaki H, Miyazaki K, Fukasawa T, Furukori H, Sugawara N, Shimoda K

“…Therefore, in this study, we retrospectively evaluated schizophrenia patients with available data for 20 years to determine whether the drug treatments in the same patients have changed in the past 20 years.Methods: The study began in April 2021 and was conducted in 15 psychiatric hospitals in Japan. Schizophrenia patients treated in the same hospital for 20 years were retrospectively examined for all prescriptions in 2016, 2011, 2006, and 2001 (ie, every 5 years).Results: The mean age of the 716 patients surveyed in 2021 was 61.7 years, with 49.0% being female. …”
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