TGFα Promotes Chemoresistance of Malignant Pleural Mesothelioma by Bernard Staumont, Majeed Jamakhani, Chrisostome Costa, Fabian Vandermeers, Sathya Neelature Sriramareddy, Gaëlle Redouté, Céline Mascaux, Philippe Delvenne, Pascale Hubert, Roghaiyeh Safari, Luc Willems

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The association of body mass index with safety and effectiveness of first-line carboplatin-based chemotherapy in patients with metastatic non-small cell lung cancer by M.P. Kicken, H.D. Kilinc, C.M. Cramer-van der Welle, S. Houterman, B.E.E.M. van den Borne, A.A.J. Smit, E.M.W. van de Garde, M.J. Deenen

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Unmet needs in EGFR exon 20 insertion mutations in Central and Eastern Europe: reimbursement, diagnostic procedures, and treatment availability by Maximilian J. Hochmair, Mojca Unk, Jelena Spasic, Timur Cerić, Assia Konsoulova, Mircea Dediu, Krisztina Bogos, Alinta Hegmane, Kersti Oselin, Marko Stojiljkovic, Tina Roblek, Marko Jakopovic

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Prevalence of Acute Kidney Injury in Covid-19 Patients- Retrospective Single-Center Study by Bashir AM, Mukhtar MS, Mohamed YG, Cetinkaya O, Fiidow OA

“…Ahmed Muhammad Bashir,1 Mahad Sadik Mukhtar,2 Yahye Garad Mohamed,3 Osman Cetinkaya,4 Osman Abubakar Fiidow5 1Department of Internal Medicine, Mogadishu Somali Turkey, Recep Tayyip Erdogan, Training and Research Hospital, Mogadishu, Somalia; 2Department of Pulmonology, Mogadishu Somali Turkey, Recep Tayyip Erdogan, Training and Research Hospital, Mogadishu, Somalia; 3Department of Radiology, Mogadishu Somali Turkey, Recep Tayyip Erdogan, Training and Research Hospital, Mogadishu, Somalia; 4Department of Emergency Medicine, Mogadishu Somali Turkey, Recep Tayyip Erdogan, Training and Research Hospital, Mogadishu, Somalia; 5School of Public Health and Research, Somali National University, Mogadishu, SomaliaCorrespondence: Ahmed Muhammad Bashir, Department of Internal Medicine, Mogadishu Somali Turkey, Recep Tayyip Erdogan, Training and Research Hospital, Mogadishu, Somalia, Tel +252612527061, Email ambashir@hotmail.comIntroduction: In December 2019, a coronavirus disease 2019 (COVID-19) disease outbreak started in Wuhan, Hubei Province, China, and spread rapidly to other regions of the world. …”
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The Risk of Sudden Death Associated with Symptomatic and Asymptomatic Ventricular Pre-excitation in Athletes by Negru Alina Gabriela, Vintilă Ana-Maria, Crișan Simina, Ana Luca Silvia, Ivănică Adrian Emil, Mihăicuță Ștefan, Cismaru Gabriel, Popescu Florina, Iovanovici Diana-Carina, Luca Constantin Tudor

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Admissions to a large tertiary care hospital and Omicron BA.1 and BA.2 SARS-CoV-2 polymerase chain reaction positivity: primary, contributing, or incidental COVID-19 by Anne F. Voor in ’t holt, Cynthia P. Haanappel, Janette Rahamat–Langendoen, Richard Molenkamp, Els van Nood, Leon M. van den Toorn, Robin P. Peeters, Annemarie M.C. van Rossum, Juliëtte A. Severin

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Multifactorial White Matter Damage in the Acute Phase and Pre-Existing Conditions May Drive Cognitive Dysfunction after SARS-CoV-2 Infection: Neuropathology-Based Evidence by Ellen Gelpi, Sigrid Klotz, Miriam Beyerle, Sven Wischnewski, Verena Harter, Harald Kirschner, Katharina Stolz, Christoph Reisinger, Elisabeth Lindeck-Pozza, Alexander Zoufaly, Marlene Leoni, Gregor Gorkiewicz, Martin Zacharias, Christine Haberler, Johannes Hainfellner, Adelheid Woehrer, Simon Hametner, Thomas Roetzer, Till Voigtländer, Gerda Ricken, Verena Endmayr, Carmen Haider, Judith Ludwig, Andrea Polt, Gloria Wilk, Susanne Schmid, Irene Erben, Anita Nguyen, Susanna Lang, Ingrid Simonitsch-Klupp, Christoph Kornauth, Maja Nackenhorst, Johannes Kläger, Renate Kain, Andreas Chott, Richard Wasicky, Robert Krause, Günter Weiss, Judith Löffler-Rag, Thomas Berger, Patrizia Moser, Afshin Soleiman, Martin Asslaber, Roland Sedivy, Nikolaus Klupp, Martin Klimpfinger, Daniele Risser, Herbert Budka, Lucas Schirmer, Anne-Katrin Pröbstel, Romana Höftberger

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Long-term effects of lumacaftor/ivacaftor on paranasal sinus abnormalities in children with cystic fibrosis detected with magnetic resonance imaging by Lena Wucherpfennig, Lena Wucherpfennig, Lena Wucherpfennig, Felix Wuennemann, Felix Wuennemann, Felix Wuennemann, Felix Wuennemann, Monika Eichinger, Monika Eichinger, Monika Eichinger, Angelika Seitz, Ingo Baumann, Mirjam Stahl, Mirjam Stahl, Mirjam Stahl, Simon Y. Graeber, Simon Y. Graeber, Simon Y. Graeber, Shengkai Zhao, Shengkai Zhao, Jaehi Chung, Jaehi Chung, Jens-Peter Schenk, Abdulsattar Alrajab, Hans-Ulrich Kauczor, Hans-Ulrich Kauczor, Hans-Ulrich Kauczor, Marcus A. Mall, Marcus A. Mall, Marcus A. Mall, Olaf Sommerburg, Olaf Sommerburg, Mark O. Wielpütz, Mark O. Wielpütz, Mark O. Wielpütz

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The Challenges of Vaccine Trial Participation among Underserved and Hard-to-Reach Communities: An Internal Expert Consultation of the VACCELERATE Consortium by Dimitrios Poulimeneas, Markela Koniordou, Dimitra Kousi, Christina Merakou, Ioannis Kopsidas, Grammatiki Christina Tsopela, Christos D. Argyropoulos, Sophia C. Themistocleous, George Shiamakkides, Marinos Constantinou, Alexandra Alexandrou, Evgenia Noula, Andria Nearchou, Jon Salmanton-García, Fiona A. Stewart, Sarah Heringer, Kerstin Albus, Elena Álvarez-Barco, Alan Macken, Romina Di Marzo, Catarina Luis, Paula Valle-Simón, Helena H. Askling, Margot Hellemans, Orly Spivak, Ruth Joanna Davis, Anna Maria Azzini, Imre Barta, Lenka Součková, Ligita Jancoriene, Murat Akova, Patrick W. G. Mallon, Ole F. Olesen, Jesus Frias-Iniesta, Pierre van Damme, Krisztina Tóth, Miriam Cohen-Kandli, Rebecca Jane Cox, Petr Husa, Pontus Nauclér, Laura Marques, Jordi Ochando, Evelina Tacconelli, Markus Zeitlinger, Oliver A. Cornely, Zoi Dorothea Pana, Theoklis E. Zaoutis

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Characterization of Patients in the International Severe Asthma Registry with High Steroid Exposure Who Did or Did Not Initiate Biologic Therapy by Chen W, Sadatsafavi M, Tran TN, Murray RB, Wong CBN, Ali N, Ariti C, Garcia Gil E, Newell A, Alacqua M, Al-Ahmad M, Altraja A, Al-Lehebi R, Bhutani M, Bjermer L, Bjerrum AS, Bourdin A, Bulathsinhala L, von Bülow A, Busby J, Canonica GW, Carter V, Christoff GC, Cosio BG, Costello RW, FitzGerald JM, Fonseca JA, Yoo KH, Heaney LG, Heffler E, Hew M, Hilberg O, Hoyte F, Iwanaga T, Jackson DJ, Jones RC, Koh MS, Kuna P, Larenas-Linnemann D, Lehmann S, Lehtimäki LA, Lyu J, Mahboub B, Maspero J, Menzies-Gow AN, Sirena C, Papadopoulos N, Papaioannou AI, Pérez de Llano L, Perng DW, Peters M, Pfeffer PE, Porsbjerg CM, Popov TA, Rhee CK, Salvi S, Taillé C, Taube C, Torres-Duque CA, Ulrik CS, Ra SW, Wang E, Wechsler ME, Price DB

“…Mary’s Hospital, College of Medicine, the Catholic University of Korea, Seoul, South Korea; 62Pulmocare Research and Education Foundation, Pune, India; 63Department of Respiratory Diseases, Bichat Hospital, AP-HP Nord-Université de Paris, Paris, France; 64Department of Pulmonary Medicine, University Medical Center Essen-Ruhrlandklinik, Essen, Germany; 65CINEUMO, Respiratory Research Center, Fundación Neumológica Colombiana, Bogotá, Colombia; 66Department of Respiratory Medicine, Copenhagen University Hospital-Hvidovre, Hvidovre, Denmark; 67Department of Internal Medicine, Division of Pulmonology, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, South Korea; 68Department of Medicine, NJH Cohen Family Asthma Institute, National Jewish Health, Denver, CO, USA; 69Centre of Academic Primary Care, Division of Applied Health Sciences, University of Aberdeen, Aberdeen, UKCorrespondence: David B Price, Observational and Pragmatic Research Institute, 22 Sin Ming Lane, #06 Midview City, Singapore, Singapore, 573969, Tel +65 3105 1489, Email dprice@opri.sgBackground: Many severe asthma patients with high oral corticosteroid exposure (HOCS) often do not initiate biologics despite being eligible. …”
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Lysophosphatidylserine induces necrosis in pressure overloaded male mouse hearts via G protein coupled receptor 34 by Ryuta Sugihara, Manabu Taneike, Tomokazu Murakawa, Takahito Tamai, Hiromichi Ueda, Rika Kitazume-Taneike, Takafumi Oka, Yasuhiro Akazawa, Hiroki Nishida, Kentaro Mine, Ayana Hioki, Jumpei Omi, Shigemiki Omiya, Junken Aoki, Kazutaka Ikeda, Kazuhiko Nishida, Makoto Arita, Osamu Yamaguchi, Yasushi Sakata, Kinya Otsu

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Three-Month Variability of Commonly Evaluated Biomarkers in Clinically Stable COPD by Park SC, Saiphoklang N, Phillips J, Wilgus ML, Buhr RG, Tashkin DP, Cooper CB, Barjaktarevic I

“…Seon Cheol Park,1,2 Narongkorn Saiphoklang,1,3 Jonathan Phillips,4 May-Lin Wilgus,1 Russell G Buhr,1 Donald P Tashkin,1 Christopher B Cooper,1,5 Igor Barjaktarevic1 1Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA; 2Division of Pulmonology, Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Republic of Korea; 3Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Thammasat University, Pathum Thani, Thailand; 4Inflammation Discovery Research, Amgen, Thousand Oaks, CA, USA; 5Exercise Physiology Research Laboratory, Department of Physiology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USACorrespondence: Igor Barjaktarevic, Division of Pulmonary and Critical Care Medicine, Department of Medicine, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA, Email IBarjaktarevic@mednet.ucla.eduIntroduction: Clinical decisions in chronic obstructive pulmonary disease (COPD) treatment often utilize serially assessed physiologic parameters and biomarkers. …”
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Chronic rhinosinusitis with nasal polyps and allergic rhinitis as different multimorbid treatable traits in asthma by José Antonio Castillo, MD, PhD, Vicente Plaza, MD, PhD, Gustavo Rodrigo, MD, PhD, Berta Juliá, MD, PhD, César Picado, MD, PhD, Cristina Fernández, MD, PhD, Joaquim Mullol, MD, PhD, FAAAAI

“…Method: Patients with asthma were prospectively recruited from 23 pulmonology and ear, nose, and throat clinics. Asthma severity and control, as well as upper airway comorbidities (AR and non-AR [NAR], CRSwNP, and CRS without nasal polyps [CRSsNP]) were assessed according to international consensus guidelines definitions. …”
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Statement on imaging and pulmonary hypertension from the Pulmonary Vascular Research Institute (PVRI) by David G. Kiely, David L. Levin, Paul M. Hassoun, Dunbar Ivy, Pei-Ni Jone, Jumaa Bwika, Steven M. Kawut, Jim Lordan, Angela Lungu, Jeremy A. Mazurek, Shahin Moledina, Horst Olschewski, Andrew J. Peacock, G.D. Puri, Farbod N. Rahaghi, Michal Schafer, Mark Schiebler, Nicholas Screaton, Merryn Tawhai, Edwin J.R. van Beek, Anton Vonk-Noordegraaf, Rebecca Vandepool, Stephen J. Wort, Lan Zhao, Jim M. Wild, Jens Vogel-Claussen, Andrew J. Swift

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Expression Profiles of AQP3 and AQP4 in Lung Adenocarcinoma Samples Generated via Bronchoscopic Biopsies by Lukasz Jaskiewicz, Karolina Hejne, Blazej Szostak, Karolina Osowiecka, Mariusz T. Skowronski, Ewa Lepiarczyk, Anna Doboszynska, Marta Majewska, Pawel Kordowitzki, Agnieszka Skowronska

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Real-world clinical practice and outcomes in treating stage III non-small cell lung cancer: KINDLE-Asia subset by Kumar Prabhash, Daniel Shao Weng Tan, Ross A. Soo, Piyada Sitthideatphaiboon, Yuh Min Chen, Pei Jye Voon, Elisna Syahruddin, Sojung Chu, Reto Huggenberger, Byoung-Chul Cho

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Robotic versus Electromagnetic bronchoscopy for pulmonary LesIon AssessmeNT: the RELIANT pragmatic randomized trial by Rafael Paez, Robert J. Lentz, Cristina Salmon, Justin K. Siemann, See-Wei Low, Jonathan D. Casey, Heidi Chen, Sheau-Chiann Chen, Sameer Avasarala, Samira Shojaee, Otis B. Rickman, Christopher J. Lindsell, Cheryl L. Gatto, Todd W. Rice, Fabien Maldonado, for the Vanderbilt Learning Healthcare System Platform Investigators

“…This will be the first known cluster randomized pragmatic trial in the interventional pulmonology field and the first randomized controlled trial of robotic-assisted bronchoscopy. …”
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A comparative analysis of the COVID-19 pandemic response: The case of Turkey by Engin Ersin Şimşek, Abdullah Emre Güner, Seval Kul, Zuhal Karakurt, Kemal Tekeşin, Suayip Birinci

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Associations between Exposure to Industrial Air Pollution and Prevalence of Asthma and Atopic Diseases in Haifa Bay Area by Raanan Raz, Yuval, Ruth Lev Bar-Or, Jeremy D. Kark, Ronit Sinnreich, David M. Broday, Ruthie Harari-Kremer, Lea Bentur, Alex Gileles-Hillel, Lital Keinan-Boker, Andrey Lyubarsky, Dorit Tsur, Arnon Afek, Noam Levin, Estela Derazne, Gilad Twig

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A Heart Rate Step Function Response Method for the Evaluation of Pulse Wave Velocity as a Predictor of Major Adverse Cardio-Vascular Events by Ioana Marin, Florina Georgeta Popescu, Elena-Ana Pauncu, Adrian Apostol, Viviana Mihaela Ivan, Catalin Nicolae Marin, Ovidiu Fira-Mladinescu, Sorin Ursoniu

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