Longitudinal IgA and IgG Response, and ACE2 Binding Blockade, to Full-Length SARS-CoV-2 Spike Protein Variants in a Population of Black PLWH Vaccinated with ChAdOx1 nCoV-19 by Muneerah Smith, Gaurav Kwatra, Alane Izu, Andrew Nel, Clare Cutland, Khatja Ahmed, Vicky Baillie, Shaun Barnabas, Qasim Bhorat, Carmen Briner, Erica Lazarus, Keertan Dheda, Lee Fairlie, Anthonet Koen, Shabir Madhi, Jonathan M. Blackburn

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Comparative Effectiveness of Umeclidinium/Vilanterol versus Inhaled Corticosteroid/Long-Acting β2-Agonist in Patients with Chronic Obstructive Pulmonary Disease in a Primary C... by Czira A, Requena G, Banks V, Wood R, Tritton T, Castillo CM, Yeap J, Wild R, Compton C, Rothnie KJ, Herth F, Quint JK, Ismaila AS

“…Alexandrosz Czira,1 Gema Requena,1 Victoria Banks,2 Robert Wood,2 Theo Tritton,2 Catherine M Castillo,2 Jie Yeap,2 Rosie Wild,2 Chris Compton,1 Kieran J Rothnie,1 Felix Herth,3,4 Jennifer K Quint,5 Afisi S Ismaila6,7 1R&D Global Medical, GSK, Brentford, Middlesex, UK; 2Real-World Evidence, Adelphi Real World, Bollington, Cheshire, UK; 3Department of Pulmonology and Respiratory Care Medicine, Thoraxklinik at the University of Heidelberg, Heidelberg, Germany; 4Translational Lung Research Center Heidelberg, Member of the German Center for Lung Research DZL, Heidelberg, Germany; 5National Heart and Lung Institute, Imperial College London, London, UK; 6Value Evidence and Outcomes, GSK, Collegeville, PA, USA; 7Department of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, CanadaCorrespondence: Alexandrosz Czira, Value Evidence and Outcomes, R&D Global Medical, GSK, Brentford, Middlesex, UK, Tel +44 7788 351610, Email alexandrosz.x.czira@gsk.comPurpose: To compare adherence to once-daily umeclidinium/vilanterol (UMEC/VI), a long-acting muscarinic antagonist/long-acting β2-agonist (LAMA/LABA), and twice-daily inhaled corticosteroids (ICS)/LABA single-inhaler dual therapy in patients with chronic obstructive pulmonary disease (COPD) in a primary care cohort in England.Patients and Methods: Active comparator, new-user, retrospective cohort study using CPRD-Aurum primary care data and linked Hospital Episode Statistics secondary care administrative data. …”
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Growth pattern in children with X-linked hypophosphatemia treated with burosumab and growth hormone by Diana-Alexandra Ertl, Justin Le Lorier, Andreas Gleiss, Séverine Trabado, Candace Bensignor, Christelle Audrain, Volha Zhukouskaya, Régis Coutant, Jugurtha Berkenou, Anya Rothenbuhler, Gabriele Haeusler, Agnès Linglart

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Angiopoietin-2 is associated with capillary leak and predicts complications after cardiac surgery by Jakob Wollborn, Zilu Zhang, Julie Gaa, Moritz Gentner, Christian Hausmann, Felix Saenger, Karina Weise, Samuel Justice, Jean-Luca Funk, Hans Felix Staehle, Marie Thomas, Raphael R. Bruno, Babak Saravi, Jan O. Friess, Markus Marx, Hartmut Buerkle, Georg Trummer, Jochen D. Muehlschlegel, Daniel Reker, Ulrich Goebel, Felix Ulbrich

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The ARISCAT Risk Index as a Predictor of Pulmonary Complications After Thoracic Surgeries, Almoosa Specialist Hospital, Saudi Arabia by Eldaabossi S, Al-Ghoneimy Y, Ghoneim A, Awad A, Mahdi W, Farouk A, Soliman H, Kanany H, Antar A, Gaber Y, Shaarawy A, Nabawy O, Atef M, Nour SO, Kabil A

“…Safwat Eldaabossi,1,2 Yasser Al-Ghoneimy,3 Ayman Ghoneim,3,4 Amgad Awad,5,6 Waheed Mahdi,2– 7 Abdallah Farouk,8,9 Hesham Soliman,10 Hatem Kanany,11 Ahmad Antar,12 Yasser Gaber,13,14 Ahmed Shaarawy,1 Osama Nabawy,1 Moaz Atef,1 Sameh O Nour,1 Ahmed Kabil1 1Department of Chest Diseases, Al-Azhar University, Cairo, Egypt; 2Pulmonology Department, Almoosa Specialist Hospital, Al Ahsa, Saudi Arabia; 3Cardiothoracic Surgery Department, Almoosa Specialist Hospital, Al Ahsa, Saudi Arabia; 4Department of Cardiothoracic Surgery, Al-Azhar University, Cairo, Egypt; 5Nephrology Department, Almoosa Specialist Hospital, Al Ahsa, Saudi Arabia; 6Department of Internal Medicine, Al-Azhar University, Cairo, Egypt; 7Department of Chest Diseases, Banha Faculty of Medicine, Banha, Egypt; 8Critical Care Consultant, Almoosa Specialist Hospital, Al Ahsa, Saudi Arabia; 9Department of Critical Care, Alexandria Faculty of Medicine, Alexandria, Egypt; 10Consultant and Chief of Anesthesia, Almoosa Specialist Hospital, Al Ahsa, Saudi Arabia; 11Department of Critical Care and Anesthesia, Al-Azhar University, Cairo, Egypt; 12Department of Internal Medicine, Hematology-Oncology Section, Almoosa Specialist Hospital, Al Ahsa, Saudi Arabia; 13Radiology Department, Almoosa Specialist Hospital, Al Ahsa, Saudi Arabia; 14Department of Radiology, Al-Azhar University, Cairo, EgyptCorrespondence: Ahmed Kabil, Department of Chest Diseases, Al-Azhar University, Cairo, Egypt, Tel +201006396601, Email a_ka_81@hotmail.comBackground: Pulmonary complications after thoracic surgery are common and are associated with prolonged hospital stay, higher costs, and increased mortality. …”
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X chromosome associations with chronic obstructive pulmonary disease and related phenotypes: an X chromosome-wide association study by Lystra P. Hayden, Brian D. Hobbs, Robert Busch, Michael H. Cho, Ming Liu, Camila M. Lopes-Ramos, David A. Lomas, Per Bakke, Amund Gulsvik, Edwin K. Silverman, James D. Crapo, Terri H. Beaty, Nan M. Laird, Christoph Lange, Dawn L. DeMeo

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Predictors of long-term employment among patients with cystic fibrosis undergoing lung transplantation by Thomas Radtke, André Königs, Xijin Chen, Julia Braun, Holger Dressel, Christian Benden

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Post-Severe-COVID-19 Cardiopulmonary Rehabilitation: A Comprehensive Study on Patient Features and Recovery Dynamics in Correlation with Workout Intensity by Andreea Dumitrescu, Gabriela Doros, Voichita Elena Lazureanu, Susa Septimiu-Radu, Felix Bratosin, Ovidiu Rosca, Harshkumar Patel, Tamara Mirela Porosnicu, Gabriela Mut Vitcu, Andrei Mirea, Cristian Oancea, Stefan Mihaicuta, Emil Robert Stoicescu, Paula Irina Barata

“…Conducted between September 2021 and September 2022, this prospective study included patients who had been diagnosed with severe COVID-19 and admitted at the “Victor Babes” Infectious Diseases and Pulmonology Hospital, Timisoara, Romania. The patients were stratified into low- and high-intensity rehabilitation groups. …”
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Consensus goals and standards for specialist cough clinics: the NEUROCOUGH international Delphi study by Woo-Jung Song, Lieven Dupont, Surinder S. Birring, Kian Fan Chung, Marta Dąbrowska, Peter Dicpinigaitis, Christian Domingo Ribas, Giovanni Fontana, Peter G. Gibson, Laurent Guilleminault, James H. Hull, Marco Idzko, Peter Kardos, Hyun Jung Kim, Kefang Lai, Federico Lavorini, Eva Millqvist, Alyn H. Morice, Akio Niimi, Sean M. Parker, Imran Satia, Jaclyn A. Smith, Jan Willem van den Berg, Lorcan P. McGarvey

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Randomised controlled trial of first-line tyrosine-kinase inhibitor (TKI) versus intercalated TKI with chemotherapy for EGFR-mutated nonsmall cell lung cancer by Rolof G.P. Gijtenbeek, Vincent van der Noort, Joachim G.J.V. Aerts, Jeske A. Staal-van den Brekel, Egbert F. Smit, Frans H. Krouwels, Frank A. Wilschut, T. Jeroen N. Hiltermann, Wim Timens, Ed Schuuring, Joost D.J. Janssen, Martijn Goosens, Paul M. van den Berg, A. Joop de Langen, Jos A. Stigt, Ben E.E.M. van den Borne, Harry J.M. Groen, Wouter H. van Geffen, Anthonie J. van der Wekken

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Favorable Prognosis in Patients with Recovered Pulmonary Hypertension after TAVI: An Analysis of the LAPLACE-TAVI Registry by Takuma Koike, Hiroshi Iwata, Yuichi Chikata, Shinichiro Doi, Ryo Naito, Hidetoshi Yasuda, Takehiro Funamizu, Hirohisa Endo, Sakiko Miyazaki, Shinya Okazaki, Ryosuke Higuchi, Itaru Takamisawa, Kei Sato, Harutoshi Tamura, Hiroaki Yokoyama, Tetsuya Tobaru, Shuichiro Takanashi, Minoru Tabata, Tohru Minamino

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Fathers’ preconception smoking and offspring DNA methylation by Negusse Tadesse Kitaba, Gerd Toril Mørkve Knudsen, Ane Johannessen, Faisal I. Rezwan, Andrei Malinovschi, Anna Oudin, Bryndis Benediktsdottir, David Martino, Francisco Javier Callejas González, Leopoldo Palacios Gómez, Mathias Holm, Nils Oskar Jõgi, Shyamali C. Dharmage, Svein Magne Skulstad, Sarah H. Watkins, Matthew Suderman, Francisco Gómez-Real, Vivi Schlünssen, Cecilie Svanes, John W. Holloway

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Preclinical Aortic Atherosclerosis in Adolescents With Chronic Disease by Francesca A. Ververs, Anouk L. M. Eikendal, Daniel Kofink, Roos Nuboer, Jos J. M. Westenberg, Gijs T. Hovenkamp, Jitske J.A. Kemps, Iris C. J. Coenen, Joëlle J. N. Daems, Laura R. Claus, Yillie Ju, Nico M. Wulffraat, Cornelis K. van der Ent, Claudia Monaco, Marianne Boes, Tim Leiner, Heynric B. Grotenhuis, Henk S. Schipper

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Bacterial and Fungal Superinfections in COVID-19 Patients Hospitalized in an Intensive Care Unit from Timișoara, Romania by Novacescu AN, Buzzi B, Bedreag O, Papurica M, Rogobete AF, Sandesc D, Sorescu T, Baditoiu L, Musuroi C, Vlad D, Licker M

“…Victor Babes’ Infectious Diseases and Pulmonology Clinical Hospital, Timisoara, Romania; 3Clinic of Anesthesia and Intensive Care, ‘Pius Brînzeu’ Emergency Clinical County Hospital, Timisoara, Romania; 4Department of Anaesthesia and Intensive Care, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania; 5Department of Diabetes, Nutrition and Metabolic Diseases, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania; 6Clinic of Diabetes, Nutrition and Metabolic Diseases, ‘Pius Brînzeu’ Emergency Clinical County Hospital, Timisoara, Romania; 7Department of Epidemiology, “Victor Babes” University of Medicine and Pharmacy, Timisoara, Romania; 8Multidisciplinary Research Center on Antimicrobial Resistance, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania; 9Department of Microbiology, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania; 10Clinical Laboratory, ‘Pius Brînzeu’ Emergency Clinical County Hospital, Timisoara, Romania; 11Department of Pharmacology, ‘Victor Babes’ University of Medicine and Pharmacy, Timisoara, Romania*These authors contributed equally to this workCorrespondence: Teodora Sorescu, Department of Diabetes, Nutrition and Metabolic Diseases, ‘Victor Babes’ University of Medicine and Pharmacy, 2 Eftimie Murgu Square, Timisoara, Romania, Tel +40724515424, Email sorescu.teodora@umft.roPurpose: Critically ill patients hospitalized in the intensive care unit (ICU) have an increased infection risk. …”
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Role of Non-Invasive Respiratory Supports in COVID-19 Acute Respiratory Failure Patients with Do Not Intubate Orders by Clément Medrinal, Alexis Gillet, Fairuz Boujibar, Jonathan Dugernier, Marcel Zwahlen, Bouchra Lamia, Christophe Girault, Jacques Creteur, Jean-Marc Fellrath, Laurence Haesler, Laurie Lagache, Laure Goubert, Elise Artaud Macari, Olivier Taton, Philippe Gouin, Dimitri Leduc, Olivier Van Hove, Michelle Norrenberg, Guillaume Prieur, Yann Combret, Nils Correvon, Roger Hilfiker, Olivier Contal

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Association of Clonal Hematopoiesis of Indeterminate Potential with Inflammatory Gene Expression in Patients with COPD by Stefan Kuhnert, Siavash Mansouri, Michael A. Rieger, Rajkumar Savai, Edibe Avci, Gabriela Díaz-Piña, Manju Padmasekar, Mario Looso, Stefan Hadzic, Till Acker, Stephan Klatt, Jochen Wilhelm, Ingrid Fleming, Natascha Sommer, Norbert Weissmann, Claus Vogelmeier, Robert Bals, Andreas Zeiher, Stefanie Dimmeler, Werner Seeger, Soni S. Pullamsetti

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Magnetic resonance imaging detects onset and association with lung disease severity of bronchial artery dilatation in cystic fibrosis by Patricia Leutz-Schmidt, Daiva-Elzbieta Optazaite, Olaf Sommerburg, Monika Eichinger, Sabine Wege, Eva Steinke, Simon Y. Graeber, Michael U. Puderbach, Jens-Peter Schenk, Abdulsattar Alrajab, Simon M.F. Triphan, Hans-Ulrich Kauczor, Mirjam Stahl, Marcus A. Mall, Mark O. Wielpütz

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Invasive fungal disease in COVID-19 patients: a single-center prospective observational study by Tatjana Adzic-Vukicevic, Tatjana Adzic-Vukicevic, Tatjana Adzic-Vukicevic, Milos Mladenovic, Snezana Jovanovic, Snezana Jovanovic, Ivan Soldatović, Aleksandra Radovanovic-Spurnic, Aleksandra Radovanovic-Spurnic, Aleksandra Radovanovic-Spurnic

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Bronchial Microbiota and the Stress Associated with Invasive Diagnostic Tests in Lung Cancer vs. Benign Pulmonary Diseases: A Cross-Sectional Study by Patricia Hogea, Emanuela Tudorache, Ovidiu Fira-Mladinescu, Camelia Pescaru, Diana Manolescu, Felix Bratosin, Ovidiu Rosca, Manaswini Kakarla, Florin George Horhat, Cristian Oancea

“…A cross-sectional study was conducted at the “Victor Babes” Hospital for Infectious Diseases and Pulmonology in Timisoara, Romania. A total of 33 patients with histologically diagnosed bronchopulmonary cancer and 33 control patients with benign lung pathologies underwent bronchoscopy. …”
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A Comparison of Clinical and Radiographic Signs of Nontuberculous Mycobacterial Pulmonary Disease, Destructive Drug-Resistant Pulmonary Tuberculosis and a Combination of Nontubercu... by Dmitrii Giller, Galina Scherbakova, Inga Enilenis, Ivan Martel, Oleg Kesaev, Vadim Koroev, Anna Popova, Alexandr Ilyukhin, Valeria Basangova, Sergey Smerdin, Shokirjon Mayusupov, Sergey Saenko, Olga Frolova, Veronika Vinarskaya, Lyudmila Severova

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