Mapping of Genetic Loci Conferring Resistance to Leaf Rust From Three Globally Resistant Durum Wheat Sources by Dhouha Kthiri, Alexander Loladze, Amidou N’Diaye, Kirby T. Nilsen, Sean Walkowiak, Susanne Dreisigacker, Karim Ammar, Curtis J. Pozniak

“…The QTL identified in this study and their closely linked markers are useful resources for gene pyramiding and breeding for durable leaf rust resistance in durum wheat.…”
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Application of Genomics Tools in Wheat Breeding to Attain Durable Rust Resistance by Prashanth Babu, Deepak Kumar Baranwal, Harikrishna, Dharam Pal, Hemlata Bharti, Priyanka Joshi, Brindha Thiyagarajan, Kiran B. Gaikwad, Subhash Chander Bhardwaj, Gyanendra Pratap Singh, Anupam Singh

“…Application of breeder’s friendly KASP assays in the wheat breeding program has expedited the identification and pyramiding of rust resistance alleles/genes in elite lines. …”
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Clinical and molecular characterization of 1q43q44 deletion and corpus callosum malformations: 2 new cases and literature review by Bochra Khadija, Khouloud Rjiba, Sarra Dimassi, Wafa Dahleb, Molka Kammoun, Hanen Hannechi, Najoua Miladi, Neziha Gouider-khouja, Ali Saad, Soumaya Mougou-Zerelli

“…He presented a facial dysmorphia, a psychomotor retardation, an axial hypotonia, a quadri pyramidal syndrome, a micropenis, and HCC associated with decreased volume of the periventricular white matter. …”
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Susceptibility of Fall Armyworm Field Populations to Vip3Aa/Cry Bt Maize in a Tropical Agricultural Region by Alisson Franco T. Silva, Luciana B. Silva, José B. Malaquias, Angélica S. Salustino, Domingos Francisco Correia Neto, Daniel M. Pacheco, Daniel B. Fragoso, Eliseu J. G. Pereira

“…In large portions of the Americas, its populations are managed using transgenic maize or cotton varieties producing insecticidal proteins from <i>Bacillus thuringiensis</i> (Bt), primarily Vip3Aa pyramided with Cry Bt proteins. We determined the susceptibility of FAW field populations from locations pressured with such maize hybrids for over five years. …”
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Shiga toxin 2 from enterohemorrhagic Escherichia coli induces reactive glial cells and neurovascular disarrangements including edema and lipid peroxidation in the murine brain hipp... by Clara Berdasco, Alipio Pinto, Valeria Calabró, David Arenas, Adriana Cangelosi, Patricia Geoghegan, Pablo Evelson, Jorge Goldstein

“…Results Systemic sublethal administration of Shiga toxin 2 increased the expressions of astrocytic GFAP and microglial Iba1, and decreased the expressions of endothelial glycocalyx, NeuN neurons from CA1 pyramidal layer and oligodendrocytic MBP myelin sheath from the fimbria of the hippocampus. …”
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Cytoarchitectonic Characterization and Functional Decoding of Four New Areas in the Human Lateral Orbitofrontal Cortex by Magdalena Wojtasik, Sebastian Bludau, Simon B. Eickhoff, Simon B. Eickhoff, Hartmut Mohlberg, Fatma Gerboga, Svenja Caspers, Svenja Caspers, Katrin Amunts, Katrin Amunts

“…Areas differed in cortical thickness, abundance and size of pyramidal cells in layer III and degree of granularity in layer IV. …”
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Combining yield, earliness and plant height in a single genotype: a proposal for breeding in grain sorghum (Sorghum bicolor L.) by Larissa Pereira Ribeiro, Flávio Dessaune Tardin, Cícero Beserra de Menezes, Aisy Botega Baldoni, Paulo Eduardo Teodoro, Leonardo Lopes Bhering

“…Favorable alleles for each trait are contained in different parents, which makes gene pyramiding a necessary strategy to simultaneously gathering earliness, plant height suitable for harvesting, and high yield in a single hybrid. …”
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Increased acetyl and total histone levels in post-mortem Alzheimer's disease brain by Pritika J. Narayan, Claire Lill, Richard Faull, Maurice A. Curtis, Mike Dragunow

“…The increase in acetyl histone H3 and H4 was observed in Neuronal N immunopositive pyramidal neurons in Alzheimer's disease brain. Using immunolabelling, histone markers correlated significantly with the level of glial fibrillary acidic protein and HLA-DP, -DQ and -DR immunopositive cells and with the pathological hallmarks of Alzheimer's disease (hyperphosphorylated tau load and β-amyloid plaques). …”
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Hippocampal network hyperexcitability in young transgenic mice expressing human mutant alpha-synuclein by Clare Tweedy, Nathan Kindred, Joshua Curry, Christopher Williams, John-Paul Taylor, Peter Atkinson, Fiona Randall, Daniel Erskine, Christopheer M. Morris, Amy K. Reeve, Gavin J. Clowry, Fiona E.N. LeBeau

“…Intracellular recordings from CA3 pyramidal cells showed a more depolarised resting membrane potential in hA30P mice. …”
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Modified age-dependent expression of NaV1.6 in an ALS model correlates with motor cortex excitability alterations by Luana Saba, Maria Teresa Viscomi, Alessandro Martini, Silvia Caioli, Nicola Biagio Mercuri, Ezia Guatteo, Cristina Zona

“…Recently, we have demonstrated that layer V pyramidal neurons (PNs) in the primary motor cortex (M1) of one-month old (P30) G93A ALS mice display an early hyperexcitability status compared to Control mice. …”
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Different Types of White Matter Hyperintensities in CADASIL by Edouard Duchesnay, Fouad Hadj Selem, François De Guio, Mathieu Dubois, Jean-François Mangin, Marco Duering, Stefan Ropele, Reinhold Schmidt, Martin Dichgans, Hugues Chabriat, Hugues Chabriat, Hugues Chabriat, Eric Jouvent, Eric Jouvent, Eric Jouvent

“…For instance, in multivariate analyses, larger extents of WMH in anterior temporal poles and superior frontal gyri were associated with better outcomes, while larger extents of WMH in pyramidal tracts were associated with worse outcomes, which could not be explained if WMH in these different areas shared the same mechanisms.Conclusion: The results of the present study support the hypothesis that the whole extent of WMH results from a combination of different regional populations of WMH, some of which are associated, for yet undetermined reasons, with milder forms of the disease.…”
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The GB4.0 Platform, an All-In-One Tool for CRISPR/Cas-Based Multiplex Genome Engineering in Plants by Marta Vazquez-Vilar, Víctor Garcia-Carpintero, Sara Selma, Joan M. Bernabé-Orts, Javier Sanchez-Vicente, Blanca Salazar-Sarasua, Arianna Ressa, Carmine de Paola, María Ajenjo, Jose Carlos Quintela, Asun Fernández-del-Carmen, Antonio Granell, Diego Orzáez

“…Multiplexing not only accelerates trait pyramiding but also can unveil traits hidden by functional redundancy. …”
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Influence of chemical substitution on broadband dielectric response of barium-lead M-type hexaferrite by Liudmila N Alyabyeva, Victor I Torgashev, Elena S Zhukova, Denis A Vinnik, Anatoliy S Prokhorov, Svetlana A Gudkova, David Rivas Góngora, Tomislav Ivek, Silvia Tomić, Nikolina Novosel, Damir Starešinić, Damir Dominko, Zvonko Jagličić, Martin Dressel, Dmitry A Zherebtsov, Boris P Gorshunov

“…Our results indicate a critical temperature range, 50 K <  T  < 70 K, where significant changes of the electrodynamic response occur that are interpreted as freezing of dynamical oscillations of bi-pyramidal Fe(2b) ions. In the range 5–300 K, the heat capacity shows no sign of any phase transition and is solely determined by electron and phonon contributions. …”
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Adhesion molecule L1 binds to amyloid beta and reduces Alzheimer's disease pathology in mice by Nevena Djogo, Igor Jakovcevski, Christian Müller, Hyun Joon Lee, Jin-Chong Xu, Mira Jakovcevski, Sebastian Kügler, Gabriele Loers, Melitta Schachner

“…AAV-L1 injected mice also had increased densities of inhibitory synaptic terminals on pyramidal cells in the hippocampus when compared with AAV-GFP controls. …”
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Genome-Wide Meta-Analysis of QTLs Associated with Root Traits and Implications for Maize Breeding by Krishna Sai Karnatam, Gautam Chhabra, Dinesh Kumar Saini, Rajveer Singh, Gurwinder Kaur, Umesh Preethi Praba, Pankaj Kumar, Simran Goyal, Priti Sharma, Rumesh Ranjan, Surinder K. Sandhu, Ramesh Kumar, Yogesh Vikal

“…These results could aid in QTL cloning and pyramiding in developing new maize varieties with specific root architecture for proper plant growth and development under optimum and abiotic stress conditions.…”
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Dissection of Pleiotropic QTL Regions Controlling Wheat Spike Characteristics Under Different Nitrogen Treatments Using Traditional and Conditional QTL Mapping by Xiaoli Fan, Fa Cui, Jun Ji, Jun Ji, Wei Zhang, Xueqiang Zhao, JiaJia Liu, Deyuan Meng, Yiping Tong, Tao Wang, Tao Wang, Junming Li, Junming Li, Junming Li

“…A total of 157 traditional QTLand 54 conditional loci were detected by inclusive composite interval mapping, among which three completely low N-stress induced QTL for SN and FSN (qSn-1A.1, qFsn-1B, and qFsn-7D) were found to maintain the desired spikelet fertility and kernel numbers even under N deficiency through pyramiding elite alleles. Twenty-eight stable QTL showing significant differencet in QTL detection model were found and seven genomic regions (R2D, R4A, R4B, R5A, R7A, R7B, and R7D) clustered by these stable QTL were highlighted. …”
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Ligand Modulation on the Various Structures of Three Zinc(II)-Based Coordination Polymers for Antibiotics Degradation by Min Xiong, Ying-Gui Xia, Lu Lu, Jun Wang, A. Mohanty, Yu Wu, Hiroshi Sakiyama, Mohd. Muddassir, Ying Pan

“…The structural studies demonstrated that in <b>2</b>, there are four Zn(II) centers and both centers are in different coordination environments (Zn2 has distorted tetrahedral geometry, whereas Zn1, Zn3, and Zn4 have square pyramidal geometry). Hirshfeld surfaces analysis revealed that different types of intermolecular interactions (C⋯C, H⋯C, H⋯H, O⋯C, N⋯H, and O⋯H) are present in the synthesized CPs. …”
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Probiotics and Prebiotics as a Therapeutic Strategy to Improve Memory in a Model of Middle-Aged Rats by Alejandra Romo-Araiza, Gabriela Gutiérrez-Salmeán, Emilio J. Galván, Melissa Hernández-Frausto, Gabriel Herrera-López, Hector Romo-Parra, Valentina García-Contreras, Ana María Fernández-Presas, Ricardo Jasso-Chávez, Cesar V. Borlongan, Antonio Ibarra

“…Passive properties of CA1 pyramidal cells (PCs) exhibited changes in response to the symbiotic treatment. …”
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New Cu⁺² Complexes with N-Sulfonamide Ligands: Potential Antitumor, Antibacterial, and Antioxidant Agents by Adriana Corina Hangan, Alexandru Turza, Roxana Liana Lucaciu, Bogdan Sevastre, Emőke Páll, Luminița Simona Oprean, Gheorghe Borodi

“…The complexes have a distorted square pyramidal square-planar geometry. The compounds were characterized by FT-IR, electronic EPR spectroscopy, and magnetic methods. …”
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Prior Attention Enhanced Convolutional Neural Network Based Automatic Segmentation of Organs at Risk for Head and Neck Cancer Radiotherapy by Haibin Chen, Dongyun Huang, Li Lin, Zhenyu Qi, Peiliang Xie, Jun Wei, Lin Chang, Ying Sun, Dongmei Wu, Yao Lu

“…The SRSF is built with a multiscale segmentation concept, in which OARs are segmented from coarse to fine. PANet is a pyramidal architecture with elements of inception block and prior attention. …”
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