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401
QTL mapping and transcriptome analysis of sugar content during fruit ripening of Pyrus pyrifolia
Published 2023-03-01“…In this study, we performed quantitative trait locus (QTL) mapping of sugar content. Two QTLs (qSugar-LG6-Chr7 and qSugar-LG12-Chr3) were identified based on their total sugar contents. …”
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402
Studies on the Molecular Basis of Heterosis in <i>Arabidopsis thaliana</i> and Vegetable Crops
Published 2023-03-01“…Analysis of noncoding RNAs has suggested their involvement in regulating the heterosis of vegetative and fruit tissues. Quantitative trait locus (QTL) analysis has revealed the association of heterozygosity of a specific locus or multiple loci with heterosis of vegetative and fruit tissues. …”
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403
Human rs75776403 polymorphism links differential phenotypic and clinical outcomes to a CLEC18A p.T151M-driven multiomics
Published 2022-06-01“…Results We identified a missense cis-acting expression quantitative trait locus in CLEC18A (rs75776403) in which the altered residue (T151→M151) disrupts the lipid-binding ability of the protein domain. …”
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404
Association of a single nucleotide polymorphism in <it>titin </it>gene with marbling in Japanese Black beef cattle
Published 2009-05-01“…As well as <it>EDG1</it>, the <it>titin </it>(<it>TTN</it>) gene, involved in myofibrillogenesis, has been previously shown to possess expression difference in <it>musculus longissimus </it>muscle between low-marbled and high-marbled steer groups, and to be located within genomic region of a quantitative trait locus for marbling. Thus <it>TTN </it>was considered as a positional functional candidate for the gene responsible for marbling. …”
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405
Deletion of the <i>Spata3</i> Gene Induces Sperm Alterations and In Vitro Hypofertility in Mice
Published 2021-02-01“…Thanks to the analysis of an Interspecific Recombinant Congenic Strain (IRCS), we previously defined the <i>Mafq1</i> quantitative trait locus as an interval on mouse Chromosome 1 associated with male hypofertility and ultrastructural abnormalities. …”
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406
Gains in QTL detection using an ultra-high density SNP map based on population sequencing relative to traditional RFLP/SSR markers.
Published 2011-01-01“…Huge efforts have been invested in the last two decades to dissect the genetic bases of complex traits including yields of many crop plants, through quantitative trait locus (QTL) analyses. However, almost all the studies were based on linkage maps constructed using low-throughput molecular markers, e.g. restriction fragment length polymorphisms (RFLPs) and simple sequence repeats (SSRs), thus are mostly of low density and not able to provide precise and complete information about the numbers and locations of the genes or QTLs controlling the traits. …”
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407
Bulk segregant analysis coupled with transcriptomics and metabolomics revealed key regulators of bacterial leaf blight resistance in rice
Published 2023-06-01“…Results The differential subtraction method in BSA identified a quantitative trait locus (QTL) on chromosome 11 spanning a 27-27.45 Mb region with 33 genes and 4 differentially expressed genes (DEGs). …”
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408
Genetics of the Inverse Relationship between Grain Yield and Grain Protein Content in Common Wheat
Published 2022-08-01“…To fill this gap, we performed quantitative trait locus (QTL) analysis for GY, GPC, and four derived GY-GPC indices using an eight-way multiparent advanced generation intercross population comprising 394 lines. …”
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409
The ecology and quantitative genetics of seed and seedling traits in upland and lowland ecotypes of a perennial grass
Published 2022-12-01“…Finally, we evaluate the genetic architecture of ecotypic divergence for these traits with quantitative trait locus (QTL) mapping. Field experiments reveal little plasticity but support a hypothesis of adaptation divergence among ecotypes based on recruitment. …”
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410
Fine-Mapping Analysis of the Genes Associated with Pre-Harvest Sprouting Tolerance in Rice (<i>Oryza sativa</i> L.)
Published 2023-03-01“…Fine mapping was carried out to identify genes associated with PHS; the detected quantitative trait locus (QTL) was narrowed down to 50 Kbp using F<sub>3:4</sub> populations, four polymorphic insertion and deletion (InDel) markers, and two cleaved amplified polymorphic sequence (CAPS) markers. …”
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411
Advances in Mushroom Research in the Last Decade
Published 2006-01-01“…The complex traits such as yield, resistance to disease and quality characteristics, and quantitative traits more than one quantitative trait locus (QTL) are found and used in practice. …”
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412
Network analysis of aging acceleration reveals systematic properties of 11 types of cancers
Published 2019-07-01“…In addition, we constructed bipartite networks of mutations and expression, and the differential expression modules related to aging‐associated mutations were selected in 11 types of cancers using the expression quantitative trait locus method. The results of enrichment analyses also identified common functions across cancers and cancer‐specific characteristics of aging acceleration. …”
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413
Identification of Candidate Gene for Internode Length in Rice to Enhance Resistance to Lodging Using QTL Analysis
Published 2021-07-01“…Traits related to the length of the panicle (LP), uppermost internode (LUI), second internode (LSI), third internode (LTI), fourth internode (LFI), lowest internode (LLI) as well as stem diameter at the uppermost internode (SDUI), second internode (SDSI), third internode (SDTI), fourth internode (SDFI), and lowest internode (SDLI) in 120 Cheongcheong/Nagdong doubled haploid population were investigated using a quantitative trait locus (QTL) analysis. Thirty-four QTL regions affected LP and the length of each internode. …”
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414
Sex chromosome turnover contributes to genomic divergence between incipient stickleback species.
Published 2014-03-01“…Furthermore, previous quantitative trait locus (QTL) mapping demonstrated that the Japan Sea neo-X chromosome contributes to phenotypic divergence and reproductive isolation between these sympatric species. …”
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415
Improved detection of gene-microbe interactions in the mouse skin microbiota using high-resolution QTL mapping of 16S rRNA transcripts
Published 2017-06-01“…Abstract Background Recent studies highlight the utility of quantitative trait locus (QTL) mapping for determining the contribution of host genetics to interindividual variation in the microbiota. …”
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416
Evolutionarily genetic dissection of flowering behavior in Asian wild and cultivated rice
Published 2022-01-01“…Flowering asynchrony in a plant (FA) was defined as the equation, FA = DTF – DFF. Quantitative‐trait locus (QTL) analyses were performed on DFF, DTF, and FA in each of two‐density conditions in a paddy field by using 35 recombinant‐inbred lines derived from an interspecific cross between domesticated rice (Oryza sativa L.) and an annual form of its wild relatives (O. rufipogon Griff.). …”
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417
QTL mapping for seed morphology using the instance segmentation neural network in Lactuca spp
Published 2022-10-01“…In this study, we built and applied an instance segmentation-based seed morphology quantification pipeline to measure traits in seeds generated from a cross between the domesticated oilseed type cultivar ‘Oilseed’ and the wild species ‘UenoyamaMaruba’ in an automated manner. Quantitative trait locus (QTL) mapping following ddRAD-seq revealed 11 QTLs linked to 7 seed traits (area, width, length, length-to-width ratio, eccentricity, perimeter length, and circularity). …”
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418
Pleiotropy Structures Plant Height and Seed Weight Scaling in Barley despite Long History of Domestication and Breeding Selection
Published 2023-01-01“…We discovered seventeen novel SNPs (quantitative trait locus) conferring pleiotropic effect on plant height and seed weight, involving genes with function in diverse traits related to plant growth and development. …”
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419
Different genetic mechanisms mediate spontaneous versus UVR-induced malignant melanoma
Published 2019-01-01“…We mapped a strong quantitative trait locus for rapid onset spontaneous melanoma onset to Prkdc, a gene involved in detection and repair of DNA damage. …”
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420
Bayesian test for colocalisation between pairs of genetic association studies using summary statistics.
Published 2014-05-01“…An application is the integration of disease scans with expression quantitative trait locus (eQTL) studies, but any pair of GWAS datasets can be integrated in this framework. …”
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