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481
QTL mapping of seedling and field resistance to stem rust in DAKIYE/Reichenbachii durum wheat population
Published 2022-01-01“…A total of 843 single nucleotide polymorphism markers for 175 lines were used for quantitative trait locus (QTL) analyses. Composite interval mapping (CIM) identified three QTL on chromosomes 3B, 4B and 7B contributed by the resistant parent. …”
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482
Control of false discoveries in grouped hypothesis testing for eQTL data
Published 2024-04-01“…Abstract Background Expression quantitative trait locus (eQTL) analysis aims to detect the genetic variants that influence the expression of one or more genes. …”
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483
Flying Together: <i>Drosophila</i> as a Tool to Understand the Genetics of Human Alcoholism
Published 2020-09-01“…These advancements occur via approaches that essentially fall into one of two categories: (1) discovering candidate genes via human genome-wide association studies (GWAS), transcriptomics on post-mortem tissue from AUD patients, or relevant physiological connections, then using reverse genetics in flies to validate candidate genes’ roles and investigate their molecular function in the context of alcohol. (2) Utilizing flies to discover candidate genes through unbiased screens, GWAS, quantitative trait locus analyses, transcriptomics, or single-gene studies, then validating their translational role in human genetic surveys. …”
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484
Harnessing the potential of bulk segregant analysis sequencing and its related approaches in crop breeding
Published 2022-08-01“…In this regard, the bulk segregant analysis sequencing (BSA-seq) and its related approaches, viz., quantitative trait locus (QTL)-seq, bulk segregant RNA-Seq (BSR)-seq, and MutMap, have emerged as efficient methods to identify the genomic loci/QTLs controlling specific traits at high resolution, accuracy, reduced time span, and in a high-throughput manner. …”
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485
Incorporating genetic similarity of auxiliary samples into eGene identification under the transfer learning framework
Published 2024-03-01“…Abstract Background The term eGene has been applied to define a gene whose expression level is affected by at least one independent expression quantitative trait locus (eQTL). It is both theoretically and empirically important to identify eQTLs and eGenes in genomic studies. …”
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486
Extensive Homeostatic T Cell Phenotypic Variation within the Collaborative Cross
Published 2017-11-01“…This approach is based on quantitative trait locus mapping: identifying genetically variant genome regions associated with phenotypic variance in traits of interest. …”
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487
Fine Mapping and Functional Analysis of Major Regulatory Genes of Soluble Solids Content in Wax Gourd (<i>Benincasa hispida</i>)
Published 2022-06-01“…In this study, the SSC regulatory gene <i>BhSSC2.1</i> in wax gourd was mined via quantitative trait locus (QTL) mapping based on high-density genetic mapping containing 12 linkage groups (LG) and bulked segregant analysis (BSA)-seq. …”
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488
Combined genome scans for body stature in 6,602 European twins: evidence for common Caucasian loci.
Published 2007-06-01“…We performed quantitative trait locus (QTL) analysis of one of the most heritable human complex traits, adult stature (body height) using genome-wide scans performed for 3,817 families (8,450 individuals) derived from twin cohorts from Australia, Denmark, Finland, Netherlands, Sweden, and United Kingdom with an approximate ten-centimorgan microsatellite marker map. …”
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489
Natural variation reveals that intracellular distribution of ELF3 protein is associated with function in the circadian clock
Published 2014-05-01“…Extensive variation led us to identify EARLY FLOWERING3 (ELF3) as a major quantitative trait locus (QTL). The causal nucleotide polymorphism caused a short-period phenotype under light and severely dampened rhythm generation in darkness, and entrainment alterations resulted. …”
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490
A MAPKKK gene from rice, RBG1res, confers resistance to Burkholderia glumae through negative regulation of ABA
Published 2023-03-01“…When previously screening for resistance against B. glumae in the resistant cultivar Nona Bokra (NB) versus the susceptible cultivar Koshihikari (KO), we detected a gene, Resistance to Burkholderia glumae 1 (RBG1), at a quantitative trait locus (QTL). Here, we found that RBG1 encodes a MAPKKK gene whose product phosphorylates OsMKK3. …”
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491
Assessing the power of tag SNPs in the mapping of quantitative trait loci (QTL) with extremal and random samples
Published 2005-10-01“…These tag SNPs can be extremely useful for testing the association of a marker locus with a qualitative or quantitative trait locus in that it may not be necessary to genotype all the SNPs. …”
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492
Genetic influences on human blood metabolites in the Japanese population
Published 2023-01-01“…In this study, we conducted a quantitative trait locus (QTL) analysis of 121 metabolites measured using gas chromatography-mass spectrometry with plasma samples from 4,888 Japanese individuals. …”
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493
Identification of candidate genes for aphid resistance in upland cotton by QTL mapping and expression analysis
Published 2023-10-01“…This study reported a lignin biosynthesis-related gene identified in the F2 population derived from the cross between cotton cultivars Xinluzao 61 (resistant to aphid) and Xinluzao 50 (susceptible to aphid). A quantitative trait locus was mapped on chromosome D04 with a logarithm of odds (LOD) score of 5.99 and phenotypic effect of 27%. …”
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494
Identification of Novel Quantitative Trait Loci for Culm Thickness of Rice Derived from Strong-Culm Landrace in Japan, Omachi
Published 2023-01-01“…In this study, we performed quantitative trait locus (QTL) analysis to identify the genetic factors of culm strength of Omachi using recombinant inbred lines (RILs) derived from a cross between Omachi and Koshihikari, a standard variety in Japan. …”
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495
CRISPR/Cas9-Mediated Disruption of Xylanase inhibitor protein (XIP) Gene Improved the Dough Quality of Common Wheat
Published 2022-04-01“…Using a unigene map of the recombinant inbred lines (RILs) for “TN 18 × LM 6,” we mapped a quantitative trait locus (QTL) for dough stability time (ST) and SDS-sedimentation values (SV) on chromosome 6A (QSt/Sv-6A-2851). …”
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496
Exploring the Influence of Growth-Associated Host Genetics on the Initial Gut Microbiota in Horses
Published 2023-06-01“…We identified 31 host–microbiome associations by utilizing 47,668 single nucleotide polymorphisms (SNPs) and 734 taxa with quantitative trait locus (QTL) information related to horse growth. …”
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497
Identification of QTL controlling the ratio of linalool to linalyl acetate in the flowers of Lavandula angustifolia Mill var. Hemus
Published 2023-11-01“…Hemus resulted in the identification of a single quantitative trait locus controlling the L/LA ratio (L/LA-QTL) and located on chromosome 8 of the lavender reference genome. …”
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498
Population size in QTL detection using quantile regression in genome-wide association studies
Published 2023-06-01“…Abstract The aim of this study was to evaluate the performance of Quantile Regression (QR) in Genome-Wide Association Studies (GWAS) regarding the ability to detect QTLs (Quantitative Trait Locus) associated with phenotypic traits of interest, considering different population sizes. …”
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499
QTL mapping of seedling and field resistance to stem rust in DAKIYE/Reichenbachii durum wheat population.
Published 2022-01-01“…A total of 843 single nucleotide polymorphism markers for 175 lines were used for quantitative trait locus (QTL) analyses. Composite interval mapping (CIM) identified three QTL on chromosomes 3B, 4B and 7B contributed by the resistant parent. …”
Get full text
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500
QTL identified that influence tuber length–width ratio, degree of flatness, tuber size, and specific gravity in a russet-skinned, tetraploid mapping population
Published 2024-03-01“…Therefore, identifying genetic regions associated with the three traits through quantitative trait locus/loci (QTL) analysis is a crucial process in the subsequent development of marker-assisted selection for use in potato breeding programs. …”
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