Hop Polyphenols in Relation to Verticillium Wilt Resistance and Their Antifungal Activity by Sabina Berne, Nataša Kovačević, Damijana Kastelec, Branka Javornik, Sebastjan Radišek

“…As suggested by quantitative trait locus (QTL) mapping and RNA-Seq analyses, the underlying molecular mechanisms of resistance in hop are complex, consisting of preformed and induced defense responses, including the synthesis of various phenolic compounds. (2) Methods: We determined the total polyphenolic content at two phenological stages in roots and stems of 14 hop varieties differing in VW resistance, examined the changes in the total polyphenols of VW resistant variety Wye Target (WT) and susceptible Celeia (CE) on infection with <i>V. nonalfalfae</i>, and assessed the antifungal activity of six commercial phenolic compounds and total polyphenolic extracts from roots and stems of VW resistant WT and susceptible CE on the growth of two different <i>V. nonalfalfae</i> hop pathotypes. (3) Results: Generally, total polyphenols were higher in roots than stems and increased with maturation of the hop. …”
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Genetic Diversity and Breeding Signatures for Regional Indica Rice Improvement in Guangdong of Southern China by Yu Hang, Liu Yue, Sun Bingrui, Liu Qing, Mao Xingxue, Jiang Liqun, Lyu Shuwei, Zhang Jing, Chen Pingli, Pan Dajian, Chen Wenfeng, Fan Zhilan, Li Chen

“…The selected regions spanning multiple yield related QTLs (quantitative trait locus) which identified by GWAS (genome-wide association studies) of the same population, and specific variations that fixed in modern cultivars of Ind II were characterized. …”
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Genetic control of thermomorphogenesis in tomato inflorescences by Shuai Sun, Zhiqiang Liu, Xiaotian Wang, Jia Song, Siyu Fang, Jisheng Kong, Ren Li, Huanzhong Wang, Xia Cui

“…Here, we identify the quantitative trait locus qMULTIPLE INFLORESCENCE BRANCH 2 (qMIB2), which modulates inflorescence branching in response to high ambient temperature in tomato (Solanum lycopersicum). …”
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APOA2: New Target for Molecular Hydrogen Therapy in Sepsis-Related Lung Injury Based on Proteomic and Genomic Analysis by Yuanlin Wang, Yan Fan, Yi Jiang, Enquan Wang, Yu Song, Hongguang Chen, Feier Xu, Keliang Xie, Yonghao Yu

“…Through analyzing expression quantitative trait locus (eQTL) and genome-wide association studies (GWAS), colocalization analysis on Apoa2 and sepsis phenotype was conducted by summary-data-based Mendelian randomization (SMR). …”
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Mapping genomic regulation of kidney disease and traits through high-resolution and interpretable eQTLs by Seong Kyu Han, Michelle T. McNulty, Christopher J. Benway, Pei Wen, Anya Greenberg, Ana C. Onuchic-Whitford, Nephrotic Syndrome Study Network (NEPTUNE), Dongkeun Jang, Jason Flannick, Noël P. Burtt, Parker C. Wilson, Benjamin D. Humphreys, Xiaoquan Wen, Zhe Han, Dongwon Lee, Matthew G. Sampson

“…Abstract Expression quantitative trait locus (eQTL) studies illuminate genomic variants that regulate specific genes and contribute to fine-mapped loci discovered via genome-wide association studies (GWAS). …”
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New Sources of Resistance and Identification of DNA Marker Loci for Sheath Blight Disease Caused by Rhizoctonia solani Kuhn, in Rice by Pachai Poonguzhali, Ashish Chauhan, Abinash Kar, Shivaji Lavale, Spurthi N. Nayak, S. K. Prashanthi

“…The putative candidate genes or quantitative trait locus harbouring at the marker interval of RM5556 and RM6208 can be further used to develop ShB resistant varieties using molecular breeding approaches.…”
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A common regulatory haplotype doubles lactoferrin concentration in milk by Thomas J. Lopdell, Alexander J. Trevarton, Janelle Moody, Claire Prowse-Wilkins, Sarah Knowles, Kathryn Tiplady, Amanda J. Chamberlain, Michael E. Goddard, Richard J. Spelman, Klaus Lehnert, Russell G. Snell, Stephen R. Davis, Mathew D. Littlejohn

“…Results We identified a highly-significant lactoferrin protein quantitative trait locus (pQTL), as well as a cis lactotransferrin (LTF) expression QTL (cis-eQTL) mapping to the LTF locus. …”
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Genetic Characterization of the Partial Disease Resistance of Rice to Bacterial Panicle Blight and Sheath Blight by Combined QTL Linkage and QTL-seq Analyses by John Christian Ontoy, Bishnu Shrestha, Hari Sharan Karki, Inderjit Barphagha, Brijesh Angira, Adam Famoso, Jong Hyun Ham

“…Genotyping was performed using Kompetitive Allele Specific PCR (KASP) assays and whole-genome sequence (WGS) analyses. Quantitative trait locus (QTL) mapping and bulk segregant analysis using a set of WGS data (QTL-seq) detected a major QTL on the upper arm of chromosome 3 for BPB, SB, and DTH traits within the 1.0–1.9 Mb position. …”
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In the name of the rose: a roadmap for rose research in the genome era by Marinus J. M. Smulders, Paul Arens, Peter M. Bourke, Thomas Debener, Marcus Linde, Jan De Riek, Leen Leus, Tom Ruttink, Sylvie Baudino, Laurence Hibrant Saint-Oyant, Jeremy Clotault, Fabrice Foucher

“…Next to a high-quality genome sequence other genomic tools have also become available for rose, including transcriptomics data, a high-density single-nucleotide polymorphism array and software to perform linkage and quantitative trait locus mapping in polyploids. Rose cultivars are highly heterogeneous and diverse. …”
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Computational Assessment of the Expression-modulating Potential for Non-coding Variants by Fang-Yuan Shi, Yu Wang, Dong Huang, Yu Liang, Nan Liang, Xiao-Wei Chen, Ge Gao

“…Large-scale genome-wide association studies (GWAS) and expression quantitative trait locus (eQTL) studies have identified multiple non-coding variants associated with genetic diseases by affecting gene expression. …”
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QTL analysis on rice genotypes adapted to acid sulfate soils in the Mekong river delta, Vietnam by Chi Buu Bui, Thi Lang Nguyen

“…RM232 was considered as a good marker linked to the target quantitative trait locus (QTL) on chromosome 3, then SR28 and OSR29 on chromosome 9 were also used. …”
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Allograft inflammatory factor-1-like is a situational regulator of leptin levels, hyperphagia, and obesity by Dippal Parikh, Smitha Jayakumar, Gustavo H. Oliveira-Paula, Vanessa Almonte, Dario F. Riascos-Bernal, Nicholas E.S. Sibinga

“…Here, we identify reductions in leptin levels, food intake, and obesity due to high-fat diet, accompanied by increased leptin sensitivity, in mice that harbor the E2a-Cre transgene within Obrq2, an obesity quantitative trait locus (QTL) that includes the leptin gene. …”
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Characterization of the <i>Ghd8</i> Flowering Time Gene in a Mini-Core Collection of <i>Miscanthus sinensis</i> by Zhihui Guo, Meilan Xu, Hironori Nagano, Lindsay V. Clark, Erik J. Sacks, Toshihiko Yamada

“…Here, we report on the sequence characterization and gene expression of <i>Miscanthus sinensis</i><i>Ghd8</i>, a transcription factor encoding a HAP3/NF-YB DNA-binding domain, which has been identified as a major quantitative trait locus in rice, with pleiotropic effects on grain yield, heading date and plant height. …”
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Genetic dissection of quantitative trait Loci for hemostasis and thrombosis on mouse chromosomes 11 and 5 using congenic and subcongenic strains. by Jane Hoover-Plow, Qila Sa, Menggui Huang, Jessica Grondolsky

“…The objective of this study was to narrow the quantitative trait locus (QTL) intervals previously identified for hemostasis and thrombosis on mouse distal chromosome 11 (Hmtb6) and on chromosome 5 (Hmtb4 and Hmtb5). …”
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Genome-wide association studies reveal novel QTLs, QTL-by-environment interactions and their candidate genes for tocopherol content in soybean seed by Kuanwei Yu, Huanran Miao, Hongliang Liu, Jinghang Zhou, Meinan Sui, Yuhang Zhan, Ning Xia, Xue Zhao, Yingpeng Han

“…Genome-wide association studies (GWAS) is an efficient method to detect quantitative trait locus (QTL), and has dissected many complex traits in soybean [Glycine max (L.) …”
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Splicing annotation of endometrial cancer GWAS risk loci reveals potentially causal variants and supports a role for NF1 and SKAP1 as susceptibility genes by Daffodil M. Canson, Tracy A. O’Mara, Amanda B. Spurdle, Dylan M. Glubb

“…To systematically assess GWAS variants for splicing effects, we developed a prioritization workflow using a combination of splicing prediction tools, alternative transcript isoforms, and splicing quantitative trait locus (sQTL) annotations. Application of this workflow to candidate causal variants from 16 endometrial cancer GWAS risk loci highlighted single-nucleotide polymorphisms (SNPs) that were predicted to upregulate alternative transcripts. …”
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Identification of QTLs for Reduced Susceptibility to Rose Rosette Disease in Diploid Roses by Ellen L. Young, Jeekin Lau, Nolan B. Bentley, Zena Rawandoozi, Sara Collins, Mark T. Windham, Patricia E. Klein, David H. Byrne, Oscar Riera-Lizarazu

“…Therefore, we performed a quantitative trait locus (QTL) analysis on a set of inter-related diploid rose populations phenotyped for RRD resistance and identified four QTLs. …”
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Construction of Three High-Density Genetic Linkage Maps and Dynamic QTL Mapping of Growth Traits in Yellow River Carp (<i>Cyprinus carpio haematopterus</i>) by Lei Wang, Songpeng Jia, Yuxuan Zhang, Shuhong Jiang, Yuhan Chen, Junping Chen, Miao Yu, Lan Zhang, Zhigang Qiao, Xuejun Li

“…To provide the theoretical basis for researching growth, development, and molecular marker-assisted breeding of the economically important Yellow River carp (<i>Cyprinus carpio haematopterus</i>) using dynamic quantitative trait locus (QTL) mapping, we constructed three genetic linkage maps from 207 progeny using a new modified genotyping-by-sequencing method. …”
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RNA-seq transcriptome analysis of the immature seeds of two Brassica napus lines with extremely different thousand-seed weight to identify the candidate genes related to seed weigh... by Xinxin Geng, Na Dong, Yuquan Wang, Gan Li, Lijun Wang, Xuejiao Guo, Jiabing Li, Zhaopu Wen, Wenhui Wei

“…A DEG (GSBRNA2T00037121001) identified by the transcriptome analysis was also previously identified in a quantitative trait locus (QTL) region for seed weight via SLAF-seq (Specific Locus Amplified Fragment sequencing). …”
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Genetic Mapping and QTL Analysis of Fruit Traits in Melon (<i>Cucumis melo</i> L.) by Haiyong Zhao, Taifeng Zhang, Xiaobing Meng, Jiayan Song, Chen Zhang, Peng Gao

“…In this study, a quantitative trait locus (QTL) mapping strategy was used to identify the potential genetic loci controlling quality traits of melons (i.e., exocarp and pericarp firmness and soluble solid content) based on newly derived whole-genome single nucleotide polymorphism-based cleaved amplified polymorphic sequence (SNP-CAPS) markers. …”
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