Metabolite and Proteomic Profiling of Serum Reveals the Differences in Molecular Immunity between Min and Large White Pig Breeds by Liyu Yang, Xin Liu, Xiaoyu Huang, Longchao Zhang, Hua Yan, Xinhua Hou, Lixian Wang, Ligang Wang

“…Correlation network analysis showed that 15 proteins were significantly correlated with the expression of both cytokines and unsaturated fatty acid metabolites. Quantitative trait locus (QTL) co-location analysis results showed that 13 of 15 proteins co-localized with immune or polyunsaturated fatty acid (PUFA)-related QTL. …”
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Single Nucleotide Polymorphism Detection for Peach Gummosis Disease Resistance by Genome-Wide Association Study by Xiongwei Li, Jiabo Wang, Mingshen Su, Jingyi Zhou, Minghao Zhang, Jihong Du, Huijuan Zhou, Kexin Gan, Jing Jin, Xianan Zhang, Ke Cao, Weichao Fang, Lirong Wang, Huijuan Jia, Zhongshan Gao, Zhengwen Ye

“…Although a locus has been identified based on bi-parental quantitative trait locus (QTL) mapping, selection of gummosis-resistant cultivars remains challenging due to the lack of resistant parents and of the complexity of an inducing factor. …”
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Quantitative trait loci on chromosomes 9 and 19 modulate AII amacrine cell number in the mouse retina by Bridget Kulesh, Bridget Kulesh, Rachel Bozadjian, Ryan J. Parisi, Ryan J. Parisi, Stephanie A. Leong, Stephanie A. Leong, Amanda G. Kautzman, Amanda G. Kautzman, Benjamin E. Reese, Benjamin E. Reese, Patrick W. Keeley

“…Large variation in cell number is present across the RI strains, from a low of ∼57,000 cells to a high of ∼87,000 cells. Quantitative trait locus (QTL) analysis revealed three prospective controlling genomic loci, on Chromosomes (Chrs) 9, 11, and 19, each contributing additive effects that together approach the range of variation observed. …”
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Transcriptome-wide association study reveals cholesterol metabolism gene Lpl is a key regulator of cognitive dysfunction by Wei Hu, Wei Hu, Jian Liu, Jian Liu, Yaorui Hu, Qingling Xu, Tingzhi Deng, Mengna Wei, Lu Lu, Jia Mi, Jonas Bergquist, Jonas Bergquist, Fuyi Xu, Geng Tian

“…By performing expression quantitative trait locus mapping, we demonstrate that Lpl is strongly cis-regulated in the BXD hippocampus. …”
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Consensus Genetic Linkage Map Construction Based on One Common Parental Line for QTL Mapping in Wheat by Xin Hu, Yingquan Zhang, Jingjuan Zhang, Shahidul Islam, Maoyun She, Yun Zhao, Guixiang Tang, Yanjie Jiang, Junkang Rong, Wujun Ma

“…The consensus map is used for the verification of marker order, quantitative trait locus (QTL) mapping and molecular marker-assisted selection (MAS) in wheat breeding. …”
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Research Advances in Genetic Mechanisms of Major Cucumber Diseases Resistance by Yujin He, Mingming Wei, Yanyan Yan, Chao Yu, Siqi Cheng, Yihan Sun, Xiangtao Zhu, Lingling Wei, Huasen Wang, Huasen Wang, Li Miao

“…In this review, we summarize recent findings on the inheritance, molecular markers, and quantitative trait locus mapping of cucumber PM, DM, and FM resistance. …”
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Genetic Mapping, Identification, and Characterization of a Candidate Susceptibility Gene for Powdery Mildew in Cannabis sativa by George M. Stack, Ali R. Cala, Michael A. Quade, Jacob A. Toth, Luis A. Monserrate, Dustin G. Wilkerson, Craig H. Carlson, Allen Mamerto, Todd P. Michael, Seth Crawford, Christine D. Smart, Lawrence B. Smart

“…A major effect quantitative trait locus on C. sativa chromosome 1 (Chr01) and other smaller-effect quantitative trait loci (QTL) on four other chromosomes were identified. …”
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Improved Genetic Map Identified Major QTLs for Drought Tolerance- and Iron Deficiency Tolerance-Related Traits in Groundnut by Manish K. Pandey, Sunil S. Gangurde, Vinay Sharma, Santosh K. Pattanashetti, Gopalakrishna K. Naidu, Issa Faye, Falalou Hamidou, Haile Desmae, Ndjido Ardo Kane, Mei Yuan, Vincent Vadez, Shyam N. Nigam, Rajeev K. Varshney

“…In this context, an improved genetic map with 1205 loci was developed spanning 2598.3 cM with an average 2.2 cM distance between loci in the recombinant inbred line (TAG 24 × ICGV 86031) population using high-density 58K single nucleotide polymorphism (SNP) “Axiom_<i>Arachis</i>” array. Quantitative trait locus (QTL) analysis was performed using extensive phenotyping data generated for 20 drought tolerance- and two iron deficiency tolerance-related traits from eight seasons (2004–2015) at two locations in India, one in Niger, and one in Senegal. …”
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Single-step genome-wide association for selected milk fatty acids in Dual-Purpose Belgian Blue cows by H. Atashi, Y. Chen, H. Wilmot, S. Vanderick, X. Hubin, H. Soyeurt, N. Gengler

“…Although these differences in genomic regions detected may be due to the power of quantitative trait locus detection, it also suggests that candidate genes underlie the phenotypic expression of the studied traits may vary between parities and lactation stages. …”
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Development of early maturing salt-tolerant rice variety KKL(R) 3 using a combination of conventional and molecular breeding approaches by Thirumeni Saminadane, Sathyadevi Geddam, Paramasivam Krishnaswamy, Karthick Jothiganapathy, Anandhan Tamilselvan, Anandhan Tamilselvan, Bharathi Raja Ramadoss, Patil Sri Hari Reddy, Uma Shankar Singh, Rakesh Kumar Singh, John Damien Platten, Glenn B. Gregorio, Nagendra Kumar Singh, Deepak Singh Bisht, Suneetha Kota, Senguttuvel Ponnuvel, Padmavathi Guntupalli

“…This study focuses on developing an early maturing seedling stage salinity tolerant rice variety by integrating conventional breeding methods with marker assisted breeding (MAB) approaches.Methods: Seedling-stage salinity tolerance Quantitative Trait Locus (QTL) “Saltol” from the salt-tolerant parent FL478 was introduced into the high-yielding but salt-sensitive rice variety ADT 45. …”
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Genome-Wide Pleiotropy Study Identifies Association of <i>PDGFB</i> with Age-Related Macular Degeneration and COVID-19 Infection Outcomes by Jaeyoon Chung, Viha Vig, Xinyu Sun, Xudong Han, George T. O’Connor, Xuejing Chen, Margaret M. DeAngelis, Lindsay A. Farrer, Manju L. Subramanian

“…We evaluated the genetic architecture shared between AMD and COVID-19 (critical illness, hospitalization, and infections) using analyses of genetic correlations and pleiotropy (i.e., cross-phenotype meta-analysis) of AMD (<i>n</i> = 33,976) and COVID-19 (<i>n</i> ≥ 1,388,342) and subsequent analyses including expression quantitative trait locus (eQTL), differential gene expression, and Mendelian randomization (MR). …”
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A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study by Burtt Nöel P, Gianniny Lauren, Guiducci Candace, Surti Aarti, D'Agostino Ralph B, Demissie Serkalem, Manning Alisa K, Kathiresan Sekar, Melander Olle, Orho-Melander Marju, Arnett Donna K, Peloso Gina M, Ordovas Jose M, Cupples L Adrienne

“…Lack of replication may be due to inadequate statistical power to detect modest quantitative trait locus effects (i.e., <1% of trait variance explained) or reduced genomic coverage of the 100K array. …”

Genome sequencing of the staple food crop white Guinea yam enables the development of a molecular marker for sex determination by Muluneh Tamiru, Satoshi Natsume, Hiroki Takagi, Benjamen White, Hiroki Yaegashi, Motoki Shimizu, Kentaro Yoshida, Aiko Uemura, Kaori Oikawa, Akira Abe, Naoya Urasaki, Hideo Matsumura, Pachakkil Babil, Shinsuke Yamanaka, Ryo Matsumoto, Satoru Muranaka, Gezahegn Girma, Antonio Lopez-Montes, Melaku Gedil, Ranjana Bhattacharjee, Michael Abberton, P. Lava Kumar, Ismail Rabbi, Mai Tsujimura, Toru Terachi, Wilfried Haerty, Manuel Corpas, Sophien Kamoun, Günter Kahl, Hiroko Takagi, Robert Asiedu, Ryohei Terauchi

“…To infer the genetics of sex determination, we performed whole-genome resequencing of bulked segregants (quantitative trait locus sequencing [QTL-seq]) in F1 progeny segregating for male and female plants and identified a genomic region associated with female heterogametic (male = ZZ, female = ZW) sex determination. …”
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The QTL and Candidate Genes Regulating the Early Tillering Vigor Traits of Late-Season Rice in Double-Cropping Systems by Wei Wu, Tian-Tian Zhang, Li-Li You, Zi-Yi Wang, Si-Qi Du, Hai-Yan Song, Zao-Hai Wang, Ying-Jin Huang, Jiang-Lin Liao

“…In this study, the candidate genes in regulating ETV traits have been sought by quantitative trait locus (QTL) mapping and bulk-segregation analysis by resequencing method (BSA-seq) conjoint analysis using rice backcross inbred line (BIL) populations, which were cultivated as late-season rice of double-cropping rice systems. …”
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Morphological Analyses and QTL Mapping of Mottled Leaf in Zucchini (<i>Cucurbita pepo</i> L.) by Kexin Wang, Xinyu Wang, Lijing Zhang, Yichen Chi, Yusong Luo, Wenlong Xu, Yunli Wang, Shuping Qu

“…Based on the strategy of quantitative trait locus sequencing (QTL-seq), two QTLs were identified on chromosomes 1 and 17, named <i>CpML1.1</i> and <i>CpML17.1</i>, respectively. …”
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QTL analysis of early flowering of female flowers in zucchini (Cucurbita pepo L.) by Shu-ping QU, Dan YANG, Hai-yang YU, Fang-yuan CHEN, Ke-xin WANG, Wen-qi DING, Wen-long XU, Yun-li WANG

“…Based on the strategy of quantitative trait locus (QTL) sequencing (QTL-seq) combined with linkage analysis, three QTLs for DFF were identified on chromosomes 4, 11, and 20. …”
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Linkage Analysis and Multi-Locus Genome-Wide Association Studies Identify QTNs Controlling Soybean Plant Height by Yanlong Fang, Shulin Liu, Quanzhong Dong, Kaixin Zhang, Zhixi Tian, Xiyu Li, Wenbin Li, Zhongying Qi, Yue Wang, Xiaocui Tian, Jie Song, Jiajing Wang, Chang Yang, Sitong Jiang, Wen-Xia Li, Hailong Ning

“…We performed quantitative trait locus (QTL) analysis by applying pre-built simple-sequence repeat maps. …”
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Isolation of a Novel QTL, <i>qSCM4,</i> Associated with Strong Culm Affects Lodging Resistance and Panicle Branch Number in Rice by Xianli Yang, Yongcai Lai, Lizhi Wang, Minghui Zhao, Jiayu Wang, Mingxian Li, Liyong Chi, Guoyi Lv, Youhong Liu, Zhibo Cui, Rui Li, Liren Wu, Bing Sun, Xijuan Zhang, Shukun Jiang

“…We identified a major quantitative trait locus (QTL), <i>qSCM4,</i> for resistance to lodging by using an F₂ segregant population and a recombinant self-incompatible line population from the cross between Shennong265 (SN265) and Lijiangxintuanheigu (LTH) after multiple years and multiple environments. …”
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Evaluation of Short-Season Soybean Genotypes for Resistance and Partial Resistance to <i>Phytophthora sojae</i> by Shengfu He, Xiran Wang, Xiaohui Sun, Yuxin Zhao, Simei Chen, Ming Zhao, Junjiang Wu, Xiaoyu Chen, Chuanzhong Zhang, Xin Fang, Yan Sun, Bo Song, Shanshan Liu, Yaguang Liu, Pengfei Xu, Shuzhen Zhang

“…Losses caused by <i>P. sojae</i> can be controlled by both major genes and quantitative trait locus. Here, we tested 112 short-season soybean cultivars from Northeast China for resistance to <i>P. sojae</i>. …”
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QTL Analysis of Yield and End-Use Quality Traits in Texas Hard Red Winter Wheat by Mehmet Dogan, Zhen Wang, Mustafa Cerit, Jorge L. Valenzuela-Antelo, Smit Dhakal, Chenggen Chu, Qingwu Xue, Amir M. H. Ibrahim, Jackie C. Rudd, Amy Bernardo, Paul St. Amand, Guihua Bai, Hongbin Zhang, Shuyu Liu

“…Genetic dissection of complex traits by quantitative trait locus (QTL) analysis permits the understanding of the genotypic effects of QTL, interactions between QTLs, and QTL-by-environment interactions in wheat. …”
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