Transcriptome sequencing and expression analysis in peanut reveal the potential mechanism response to Ralstonia solanacearum infection by Xiao Wang, Feiyan Qi, Ziqi Sun, Hongfei Liu, Yue Wu, Xiaohui Wu, Jing Xu, Hua Liu, Li Qin, Zhenyu Wang, Suling Sang, Wenzhao Dong, Bingyan Huang, Zheng Zheng, Xinyou Zhang

“…Based on our previous quantitative trait locus (QTL) mapping results, the genes arahy.V6I7WA and arahy.MXY2PU, which encode nucleotide-binding site-leucine-rich repeat receptor proteins, were indicated to be associated with resistance to bacterial wilt. …”
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Unraveling the causal genes and transcriptomic determinants of human telomere length by Ying Chang, Yao Zhou, Junrui Zhou, Wen Li, Jiasong Cao, Yaqing Jing, Shan Zhang, Yongmei Shen, Qimei Lin, Xutong Fan, Hongxi Yang, Xiaobao Dong, Shijie Zhang, Xianfu Yi, Ling Shuai, Lei Shi, Zhe Liu, Jie Yang, Xin Ma, Jihui Hao, Kexin Chen, Mulin Jun Li, Feng Wang, Dandan Huang

“…Next, we integrate the powerful TL GWAS with placental expression quantitative trait locus (eQTL) mapping to prioritize 23 likely causal genes, among which 4 are functionally validated, including MMUT, RRM1, KIAA1429, and YWHAZ. …”
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A toxin-antidote system contributes to interspecific reproductive isolation in rice by Shimin You, Zhigang Zhao, Xiaowen Yu, Shanshan Zhu, Jian Wang, Dekun Lei, Jiawu Zhou, Jing Li, Haiyuan Chen, Yanjia Xiao, Weiwei Chen, Qiming Wang, Jiayu Lu, Keyi Chen, Chunlei Zhou, Xin Zhang, Zhijun Cheng, Xiuping Guo, Yulong Ren, Xiaoming Zheng, Shijia Liu, Xi Liu, Yunlu Tian, Ling Jiang, Dayun Tao, Chuanyin Wu, Jianmin Wan

“…Here, we report the cloning of qHMS1, a quantitative trait locus controlling hybrid male sterility between these two species. …”
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Genome-wide association study of cooking-caused grain expansion in rice (Oryza sativa L.) by Yan Zheng, Yan Zheng, Yan Zheng, Khin Mar Thi, Khin Mar Thi, Lihui Lin, Lihui Lin, Xiaofang Xie, Xiaofang Xie, Xiaofang Xie, Ei Ei Khine, Ei Ei Khine, Ei Ei Nyein, Ei Ei Nyein, Min Htay Wai Lin, Win Win New, San San Aye, Weiren Wu, Weiren Wu

“…Cooking-caused rice grain expansion (CCRGE) is a critical trait for evaluating the cooking quality of rice. Previous quantitative trait locus (QTL) mapping studies on CCRGE have been limited to bi-parental populations, which restrict the exploration of natural variation and mapping resolution. …”
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Comparative genomic analyses reveal the genetic basis of the yellow-seed trait in Brassica napus by Cunmin Qu, Meichen Zhu, Ran Hu, Yongchao Niu, Si Chen, Huiyan Zhao, Chengxiang Li, Zhen Wang, Nengwen Yin, Fujun Sun, Zhiyou Chen, Shulin Shen, Guoxia Shang, Yan Zhou, Xingying Yan, Lijuan Wei, Liezhao Liu, Bin Yi, Jinmin Lian, Jiang Li, Zhanglin Tang, Ying Liang, Xinfu Xu, Rui Wang, Jiaming Yin, Huafang Wan, Hai Du, Wei Qian, Yourong Chai, Qingyuan Zhou, Yajun He, Silin Zhong, Xiao Qiu, Hao Yu, Hon-Ming Lam, Kun Lu, Fuyou Fu, Jiana Li

“…Combining in-depth fine mapping of a quantitative trait locus (QTL) for seed color with other omics data reveal BnA09MYB47a, encoding an R2R3-MYB-type transcription factor, as the causal gene of a major QTL controlling the yellow-seed trait. …”
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Performance Comparison of Computational Methods for the Prediction of the Function and Pathogenicity of Non-coding Variants by Zheng Wang, Guihu Zhao, Bin Li, Zhenghuan Fang, Qian Chen, Xiaomeng Wang, Tengfei Luo, Yijing Wang, Qiao Zhou, Kuokuo Li, Lu Xia, Yi Zhang, Xun Zhou, Hongxu Pan, Yuwen Zhao, Yige Wang, Lin Wang, Jifeng Guo, Beisha Tang, Kun Xia, Jinchen Li

“…To solve this issue, we assessed 12 performance metrics of 24 methods on four independent non-coding variant benchmark datasets: (1) rare germline variants from clinical relevant sequence variants (ClinVar), (2) rare somatic variants from Catalogue Of Somatic Mutations In Cancer (COSMIC), (3) common regulatory variants from curated expression quantitative trait locus (eQTL) data, and (4) disease-associated common variants from curated genome-wide association studies (GWAS). …”
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Regulation of Fn14 Receptor and NF-κB Underlies Inflammation in Meniere’s Disease by Lidia Frejo, Teresa Requena, Satoshi Okawa, Alvaro Gallego-Martinez, Manuel Martinez-Bueno, Ismael Aran, Angel Batuecas-Caletrio, Jesus Benitez-Rosario, Juan M. Espinosa-Sanchez, Juan M. Espinosa-Sanchez, Jesus José Fraile-Rodrigo, Ana María García-Arumi, Rocío González-Aguado, Pedro Marques, Eduardo Martin-Sanz, Nicolas Perez-Fernandez, Paz Pérez-Vázquez, Herminio Perez-Garrigues, Sofía Santos-Perez, Andres Soto-Varela, Maria C. Tapia, Gabriel Trinidad-Ruiz, Antonio del Sol, Marta E. Alarcon Riquelme, Marta E. Alarcon Riquelme, Jose A. Lopez-Escamez, Jose A. Lopez-Escamez, Jose A. Lopez-Escamez

“…Gene expression profiles of homozygous genotype-selected peripheral blood mononuclear cells (PBMCs) demonstrated that this region is a trans-expression quantitative trait locus (eQTL) in PBMCs. Signaling analysis predicted several tumor necrosis factor-related pathways, the TWEAK/Fn14 pathway being the top candidate (p = 2.42 × 10−11). …”
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Identification of Novel Genomic Regions for Bacterial Leaf Pustule (BLP) Resistance in Soybean (<i>Glycine max</i> L.) via Integrating Linkage Mapping and Association Analysis by Fangzhou Zhao, Wei Cheng, Yanan Wang, Xuewen Gao, Debao Huang, Jiejie Kong, Augustine Antwi-Boasiako, Lingyi Zheng, Wenliang Yan, Fangguo Chang, Keke Kong, Ying-Yu Liao, Alejandra I. Huerta, Wusheng Liu, Mengchen Zhang, Tuanjie Zhao

“…Using a linkage mapping in a recombinant inbred line (RIL) population against the Xag strain Chinese C5, we identified that quantitative trait locus (QTL) <i>qrxp–17–2</i> accounted for 74.33% of the total phenotypic variations. …”
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Identification of genetic loci for grain yield-related traits in the wheat population Zhongmai 578/Jimai 22 by Dan LIU, De-hui ZHAO, Jian-qi ZENG, Rabiu Sani SHAWAI, Jing-yang TONG, Ming LI, Fa-ji LI, Shuo ZHOU, Wen-li HU, Xian-chun XIA, Yu-bing TIAN, Qian ZHU, Chun-ping WANG, De-sen WANG, Zhong-hu HE, Jin-dong LIU, Yong ZHANG

“…The identification of stable quantitative trait locus (QTL) for yield-related traits and tightly linked molecular markers is important for improving wheat grain yield. …”
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Identification and Pyramiding Major QTL Loci for Simultaneously Enhancing Aflatoxin Resistance and Yield Components in Peanut by Gaorui Jin, Nian Liu, Bolun Yu, Yifei Jiang, Huaiyong Luo, Li Huang, Xiaojing Zhou, Liying Yan, Yanping Kang, Dongxin Huai, Yinbing Ding, Yuning Chen, Xin Wang, Huifang Jiang, Yong Lei, Jinxiong Shen, Boshou Liao

“…In this study, an RIL population derived from a cross between Zhonghua 16 with high yield and J 11 with resistance to infection of <i>A. flavus</i> and aflatoxin production, was used to identify quantitative trait locus (QTL) for aflatoxin production (AP) resistance and hundred-seed weight (HSW). …”
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BrMYB108 confers resistance to Verticillium wilt by activating ROS generation in Brassica rapa by Tongbing Su, Weihong Wang, Zheng Wang, Peirong Li, Xiaoyun Xin, Yangjun Yu, Deshuang Zhang, Xiuyun Zhao, Jiao Wang, Liling Sun, Guihua Jin, Fenglan Zhang, Shuancang Yu

“…We combine a genome-wide association study in a natural population and quantitative trait locus mapping in an F2 population and identify that the MYB transcription factor BrMYB108 regulates plant resistance to VW. …”
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Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants by Kristin L. Young, Virginia Fisher, Xuan Deng, Jennifer A. Brody, Misa Graff, Elise Lim, Bridget M. Lin, Hanfei Xu, Najaf Amin, Ping An, Stella Aslibekyan, Alison E. Fohner, Bertha Hidalgo, Petra Lenzini, Robert Kraaij, Carolina Medina-Gomez, Ivana Prokić, Fernando Rivadeneira, Colleen Sitlani, Ran Tao, Jeroen van Rooij, Di Zhang, Jai G. Broome, Erin J. Buth, Benjamin D. Heavner, Deepti Jain, Albert V. Smith, Kathleen Barnes, Meher Preethi Boorgula, Sameer Chavan, Dawood Darbar, Mariza De Andrade, Xiuqing Guo, Jeffrey Haessler, Marguerite R. Irvin, Rita R. Kalyani, Sharon L.R. Kardia, Charles Kooperberg, Wonji Kim, Rasika A. Mathias, Merry-Lynn McDonald, Braxton D. Mitchell, Patricia A. Peyser, Elizabeth A. Regan, Susan Redline, Alexander P. Reiner, Stephen S. Rich, Jerome I. Rotter, Jennifer A. Smith, Scott Weiss, Kerri L. Wiggins, Lisa R. Yanek, Donna Arnett, Nancy L. Heard-Costa, Suzanne Leal, Danyu Lin, Barbara McKnight, Michael Province, Cornelia M. van Duijn, Kari E. North, L. Adrienne Cupples, Ching-Ti Liu

“…Our expression quantitative trait locus (eQTL) analysis within previously reported GWAS loci implicated CEP63 and RFT1 as potential functional genes for known height loci. …”
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Glossaire général by P. MULSANT

“…QTL : abréviation de locus à effets quantitatifs (de l’anglais Quantitative Trait Locus). Récessivité : qualificatif de l’effet d'un allèle, où l'homozygotie* est nécessaire pour l'expression du phénotype* approprié. opposé de : dominance*. …”
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Dissecting the genetic heterogeneity of gastric cancerResearch in context by Timo Hess, Carlo Maj, Jan Gehlen, Oleg Borisov, Stephan L. Haas, Ines Gockel, Michael Vieth, Guillaume Piessen, Hakan Alakus, Yogesh Vashist, Carina Pereira, Michael Knapp, Vitalia Schüller, Alexander Quaas, Heike I. Grabsch, Jessica Trautmann, Ewa Malecka-Wojciesko, Anna Mokrowiecka, Jan Speller, Andreas Mayr, Julia Schröder, Axel M. Hillmer, Dominik Heider, Florian Lordick, Ángeles Pérez-Aísa, Rafael Campo, Jesús Espinel, Fernando Geijo, Concha Thomson, Luis Bujanda, Federico Sopeña, Ángel Lanas, María Pellisé, Claudia Pauligk, Thorsten Oliver Goetze, Carolin Zelck, Julian Reingruber, Emadeldin Hassanin, Peter Elbe, Sandra Alsabeah, Mats Lindblad, Magnus Nilsson, Nicole Kreuser, René Thieme, Francesca Tavano, Roberta Pastorino, Dario Arzani, Roberto Persiani, Jin-On Jung, Henrik Nienhüser, Katja Ott, Ralf R. Schumann, Oliver Kumpf, Susen Burock, Volker Arndt, Anna Jakubowska, Małgorzta Ławniczak, Victor Moreno, Vicente Martín, Manolis Kogevinas, Marina Pollán, Justyna Dąbrowska, Antonio Salas, Olivier Cussenot, Anne Boland-Auge, Delphine Daian, Jean-Francois Deleuze, Erika Salvi, Maris Teder-Laving, Gianluca Tomasello, Margherita Ratti, Chiara Senti, Valli De Re, Agostino Steffan, Arnulf H. Hölscher, Katharina Messerle, Christiane Josephine Bruns, Armands Sīviņš, Inga Bogdanova, Jurgita Skieceviciene, Justina Arstikyte, Markus Moehler, Hauke Lang, Peter P. Grimminger, Martin Kruschewski, Nikolaos Vassos, Claus Schildberg, Philipp Lingohr, Karsten Ridwelski, Hans Lippert, Nadine Fricker, Peter Krawitz, Per Hoffmann, Markus M. Nöthen, Lothar Veits, Jakob R. Izbicki, Adrianna Mostowska, Federico Martinón-Torres, Daniele Cusi, Rolf Adolfsson, Geraldine Cancel-Tassin, Aksana Höblinger, Ernst Rodermann, Monika Ludwig, Gisela Keller, Andres Metspalu, Hermann Brenner, Joerg Heller, Markus Neef, Michael Schepke, Franz Ludwig Dumoulin, Lutz Hamann, Renato Cannizzaro, Michele Ghidini, Dominik Plaßmann, Michael Geppert, Peter Malfertheiner, Olivier Gehlen, Tomasz Skoczylas, Marek Majewski, Jan Lubiński, Orazio Palmieri, Stefania Boccia, Anna Latiano, Nuria Aragones, Thomas Schmidt, Mário Dinis-Ribeiro, Rui Medeiros, Salah-Eddin Al-Batran, Mārcis Leja, Juozas Kupcinskas, María A. García-González, Marino Venerito, Johannes Schumacher

“…For the identification of risk genes among GWAS loci we did a transcriptome-wide association study (TWAS) and expression quantitative trait locus (eQTL) study from gastric corpus and antrum mucosa. …”
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GWAS-Based Identification of New Loci for Milk Yield, Fat, and Protein in Holstein Cattle by Liyuan Liu, Jinghang Zhou, Chunpeng James Chen, Juan Zhang, Wan Wen, Jia Tian, Zhiwu Zhang, Yaling Gu

“…A total of ten single-nucleotide polymorphisms (SNPs) were detected above the genome-wide significant threshold (<i>p</i> < 4.0 × 10⁻⁷), including six located in previously reported quantitative traits locus (QTL) regions. We found eight candidate genes within distances of 120 kb upstream or downstream to the associated SNPs. …”
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The qTSN positive effect on panicle and flag leaf size of rice is associated with an early down-regulation of tillering by Dewi Erika eAdriani, Dewi Erika eAdriani, Tanguy eLafarge, Audrey eDardou, Aubrey eFabro, Anne eClement-Vidal, Sudirman eYahya, Michael eDingkuhn, Michael eDingkuhn, Delphine eLuquet

“…The qTSN4 was identified as rice QTL (Quantitative Traits Locus) increasing total spikelet number per panicle and flag leaf area but potentially reducing panicle number depending on the environment. …”
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