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821
Transcriptome sequencing and expression analysis in peanut reveal the potential mechanism response to Ralstonia solanacearum infection
Published 2024-03-01“…Based on our previous quantitative trait locus (QTL) mapping results, the genes arahy.V6I7WA and arahy.MXY2PU, which encode nucleotide-binding site-leucine-rich repeat receptor proteins, were indicated to be associated with resistance to bacterial wilt. …”
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822
Unraveling the causal genes and transcriptomic determinants of human telomere length
Published 2023-12-01“…Next, we integrate the powerful TL GWAS with placental expression quantitative trait locus (eQTL) mapping to prioritize 23 likely causal genes, among which 4 are functionally validated, including MMUT, RRM1, KIAA1429, and YWHAZ. …”
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823
A toxin-antidote system contributes to interspecific reproductive isolation in rice
Published 2023-11-01“…Here, we report the cloning of qHMS1, a quantitative trait locus controlling hybrid male sterility between these two species. …”
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824
Genome-wide association study of cooking-caused grain expansion in rice (Oryza sativa L.)
Published 2023-08-01“…Cooking-caused rice grain expansion (CCRGE) is a critical trait for evaluating the cooking quality of rice. Previous quantitative trait locus (QTL) mapping studies on CCRGE have been limited to bi-parental populations, which restrict the exploration of natural variation and mapping resolution. …”
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825
Comparative genomic analyses reveal the genetic basis of the yellow-seed trait in Brassica napus
Published 2023-08-01“…Combining in-depth fine mapping of a quantitative trait locus (QTL) for seed color with other omics data reveal BnA09MYB47a, encoding an R2R3-MYB-type transcription factor, as the causal gene of a major QTL controlling the yellow-seed trait. …”
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826
Performance Comparison of Computational Methods for the Prediction of the Function and Pathogenicity of Non-coding Variants
Published 2023-06-01“…To solve this issue, we assessed 12 performance metrics of 24 methods on four independent non-coding variant benchmark datasets: (1) rare germline variants from clinical relevant sequence variants (ClinVar), (2) rare somatic variants from Catalogue Of Somatic Mutations In Cancer (COSMIC), (3) common regulatory variants from curated expression quantitative trait locus (eQTL) data, and (4) disease-associated common variants from curated genome-wide association studies (GWAS). …”
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827
Regulation of Fn14 Receptor and NF-κB Underlies Inflammation in Meniere’s Disease
Published 2017-12-01“…Gene expression profiles of homozygous genotype-selected peripheral blood mononuclear cells (PBMCs) demonstrated that this region is a trans-expression quantitative trait locus (eQTL) in PBMCs. Signaling analysis predicted several tumor necrosis factor-related pathways, the TWEAK/Fn14 pathway being the top candidate (p = 2.42 × 10−11). …”
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828
Identification of Novel Genomic Regions for Bacterial Leaf Pustule (BLP) Resistance in Soybean (<i>Glycine max</i> L.) via Integrating Linkage Mapping and Association Analysis
Published 2022-02-01“…Using a linkage mapping in a recombinant inbred line (RIL) population against the Xag strain Chinese C5, we identified that quantitative trait locus (QTL) <i>qrxp–17–2</i> accounted for 74.33% of the total phenotypic variations. …”
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829
Identification of genetic loci for grain yield-related traits in the wheat population Zhongmai 578/Jimai 22
Published 2023-07-01“…The identification of stable quantitative trait locus (QTL) for yield-related traits and tightly linked molecular markers is important for improving wheat grain yield. …”
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830
Identification and Pyramiding Major QTL Loci for Simultaneously Enhancing Aflatoxin Resistance and Yield Components in Peanut
Published 2023-03-01“…In this study, an RIL population derived from a cross between Zhonghua 16 with high yield and J 11 with resistance to infection of <i>A. flavus</i> and aflatoxin production, was used to identify quantitative trait locus (QTL) for aflatoxin production (AP) resistance and hundred-seed weight (HSW). …”
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831
BrMYB108 confers resistance to Verticillium wilt by activating ROS generation in Brassica rapa
Published 2023-08-01“…We combine a genome-wide association study in a natural population and quantitative trait locus mapping in an F2 population and identify that the MYB transcription factor BrMYB108 regulates plant resistance to VW. …”
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832
Whole-exome sequence analysis of anthropometric traits illustrates challenges in identifying effects of rare genetic variants
Published 2023-01-01“…Our expression quantitative trait locus (eQTL) analysis within previously reported GWAS loci implicated CEP63 and RFT1 as potential functional genes for known height loci. …”
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833
Glossaire général
Published 2011-09-01“…QTL : abréviation de locus à effets quantitatifs (de l’anglais Quantitative Trait Locus). Récessivité : qualificatif de l’effet d'un allèle, où l'homozygotie* est nécessaire pour l'expression du phénotype* approprié. opposé de : dominance*. …”
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834
Dissecting the genetic heterogeneity of gastric cancerResearch in context
Published 2023-06-01“…For the identification of risk genes among GWAS loci we did a transcriptome-wide association study (TWAS) and expression quantitative trait locus (eQTL) study from gastric corpus and antrum mucosa. …”
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835
GWAS-Based Identification of New Loci for Milk Yield, Fat, and Protein in Holstein Cattle
Published 2020-11-01“…A total of ten single-nucleotide polymorphisms (SNPs) were detected above the genome-wide significant threshold (<i>p</i> < 4.0 × 10<sup>−7</sup>), including six located in previously reported quantitative traits locus (QTL) regions. We found eight candidate genes within distances of 120 kb upstream or downstream to the associated SNPs. …”
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836
The qTSN positive effect on panicle and flag leaf size of rice is associated with an early down-regulation of tillering
Published 2016-01-01“…The qTSN4 was identified as rice QTL (Quantitative Traits Locus) increasing total spikelet number per panicle and flag leaf area but potentially reducing panicle number depending on the environment. …”
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