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181
PIP2-Effector Protein MPRIP Regulates RNA Polymerase II Condensation and Transcription
Published 2023-02-01Subjects: Get full text
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182
Lack of the delta subunit of RNA polymerase increases virulence related traits of Streptococcus mutans.
Published 2011-01-01“…The delta subunit of the RNA polymerase, RpoE, maintains the transcriptional specificity in gram-positive bacteria. …”
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183
RNA polymerase III transcription and cancer: A tale of two RPC7 subunits
Published 2023-01-01“…RNA polymerase III composition is shaped by the mutually exclusive incorporation of two paralogous subunits, RPC7α and RPC7β, encoded by genes POLR3G and POLR3GL in vertebrates. …”
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184
Viroid-like RNA-dependent RNA polymerase-encoding ambiviruses are abundant in complex fungi
Published 2023-05-01“…Ambiviruses are hybrid infectious elements encoding the hallmark gene of RNA viruses, the RNA-dependent RNA polymerase, and self-cleaving RNA ribozymes found in many viroids. …”
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185
Selective Occupation by E2F and RB of Loci Expressed by RNA Polymerase III
Published 2024-01-01Subjects: Get full text
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186
Characterizing intergenic transcription at RNA polymerase II binding sites in normal and cancer tissues
Published 2023-10-01Subjects: Get full text
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187
Biochemistry of the Respiratory Syncytial Virus L Protein Embedding RNA Polymerase and Capping Activities
Published 2023-01-01“…The replication/transcription is orchestrated by the L protein, which contains three conserved enzymatic domains: the RNA-dependent RNA polymerase (RdRp), the polyribonucleotidyl transferase (PRNTase or capping), and the methyltransferase (MTase) domain. …”
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188
Nucleotide Context Can Modulate Promoter Strength in Genes Transcribed by RNA Polymerase III
Published 2023-03-01Subjects: “…RNA polymerase III…”
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189
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190
Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 Drugs
Published 2020-04-01Subjects: Get full text
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191
Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus
Published 2021-05-01Subjects: Get full text
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192
Deep mutational scanning reveals the molecular determinants of RNA polymerase-mediated adaptation and tradeoffs
Published 2023-10-01“…Abstract RNA polymerase (RNAP) is emblematic of complex biological systems that control multiple traits involving trade-offs such as growth versus maintenance. …”
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193
Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II
Published 2023-09-01“…Abstract Eukaryotic gene regulation and pre-mRNA transcription depend on the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II. Due to its highly repetitive, intrinsically disordered sequence, the CTD enables clustering and phase separation of Pol II. …”
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194
Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase
Published 2021-04-01“…Our data through cell-based and biochemical studies showed that both compounds act as SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitors directly and inhibit the activity of the SARS-CoV-2 RdRp, but baicalein was more potent. …”
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195
Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases
Published 2018-01-01Subjects: Get full text
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196
A remodeled RNA polymerase II complex catalyzing viroid RNA-templated transcription.
Published 2022-09-01“…It is well-known that nuclear-replicating viroids exploit host DNA-dependent RNA polymerase II (Pol II) activity for transcription from circular RNA genome to minus-strand intermediates, a classic example illustrating the intrinsic RNA-dependent RNA polymerase activity of Pol II. …”
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197
Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization
Published 2023-01-01“…Here, authors reported high-order structure of RNA polymerase and its role in regulation of gene expression in pathogenic bacterium.…”
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198
Revisiting Viral RNA-Dependent RNA Polymerases: Insights from Recent Structural Studies
Published 2022-10-01“…RNA-dependent RNA polymerases (RdRPs) represent a distinctive yet versatile class of nucleic acid polymerases encoded by RNA viruses for the replication and transcription of their genome. …”
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199
Common changes in global gene expression induced by RNA polymerase inhibitors in Shigella flexneri.
Published 2012-01-01“…Here, the common response of Shigella flexneri to two inhibitors of RNA polymerase was examined using gene expression profiling. …”
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200
RNA Polymerase II cluster dynamics predict mRNA output in living cells
Published 2017“…We developed a live-cell super-resolution approach to uncover the correlation between mRNA synthesis and the dynamics of RNA Polymerase II (Pol II) clusters at a gene locus. For endogenous β-actin genes in mouse embryonic fibroblasts, we observe that short-lived (~8 s) Pol II clusters correlate with basal mRNA output. …”
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