PIP2-Effector Protein MPRIP Regulates RNA Polymerase II Condensation and Transcription by Can Balaban, Martin Sztacho, Ludovica Antiga, Ana Miladinović, Masahiko Harata, Pavel Hozák

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Lack of the delta subunit of RNA polymerase increases virulence related traits of Streptococcus mutans. by Xiaoli Xue, Helena Sztajer, Nora Buddruhs, Jörn Petersen, Manfred Rohde, Susanne R Talay, Irene Wagner-Döbler

“…The delta subunit of the RNA polymerase, RpoE, maintains the transcriptional specificity in gram-positive bacteria. …”
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RNA polymerase III transcription and cancer: A tale of two RPC7 subunits by Ruiying Cheng, Kevin Van Bortle, Kevin Van Bortle

“…RNA polymerase III composition is shaped by the mutually exclusive incorporation of two paralogous subunits, RPC7α and RPC7β, encoded by genes POLR3G and POLR3GL in vertebrates. …”
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Viroid-like RNA-dependent RNA polymerase-encoding ambiviruses are abundant in complex fungi by Li Chuin Chong, Chris Lauber

“…Ambiviruses are hybrid infectious elements encoding the hallmark gene of RNA viruses, the RNA-dependent RNA polymerase, and self-cleaving RNA ribozymes found in many viroids. …”
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Selective Occupation by E2F and RB of Loci Expressed by RNA Polymerase III by Rebecca E. Sizer, Sienna P. Butterfield, Lucy A. Hancocks, Leonor Gato De Sousa, Robert J. White

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Characterizing intergenic transcription at RNA polymerase II binding sites in normal and cancer tissues by Pierre de Langen, Fayrouz Hammal, Elise Guéret, Jean-Christophe Mouren, Lionel Spinelli, Benoit Ballester

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Biochemistry of the Respiratory Syncytial Virus L Protein Embedding RNA Polymerase and Capping Activities by Priscila Sutto-Ortiz, Jean-François Eléouët, François Ferron, Etienne Decroly

“…The replication/transcription is orchestrated by the L protein, which contains three conserved enzymatic domains: the RNA-dependent RNA polymerase (RdRp), the polyribonucleotidyl transferase (PRNTase or capping), and the methyltransferase (MTase) domain. …”
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Nucleotide Context Can Modulate Promoter Strength in Genes Transcribed by RNA Polymerase III by Danil V. Stasenko, Karina A. Tatosyan, Olga R. Borodulina, Dmitri A. Kramerov

Subjects: “…RNA polymerase III…”
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Effects of the RNA-Polymerase Inhibitors Remdesivir and Favipiravir on the Structure of Lipid Bilayers—An MD Study by Mauro Bringas, Meike Luck, Peter Müller, Holger A. Scheidt, Santiago Di Lella

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Feasibility of Known RNA Polymerase Inhibitors as Anti-SARS-CoV-2 Drugs by Ujjwal Neogi, Kyle J. Hill, Anoop T Ambikan, Xiao Heng, Thomas P. Quinn, Siddappa N. Byrareddy, Anders Sönnerborg, Stefan G. Sarafianos, Kamal Singh

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Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus by Qingxing Wang, Qilin Xin, Weijuan Shang, Weiwei Wan, Gengfu Xiao, Lei-Ke Zhang

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Deep mutational scanning reveals the molecular determinants of RNA polymerase-mediated adaptation and tradeoffs by Alaksh Choudhury, Benoit Gachet, Zoya Dixit, Roland Faure, Ryan T. Gill, Olivier Tenaillon

“…Abstract RNA polymerase (RNAP) is emblematic of complex biological systems that control multiple traits involving trade-offs such as growth versus maintenance. …”
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Driving forces behind phase separation of the carboxy-terminal domain of RNA polymerase II by David Flores-Solis, Irina P. Lushpinskaia, Anton A. Polyansky, Arya Changiarath, Marc Boehning, Milana Mirkovic, James Walshe, Lisa M. Pietrek, Patrick Cramer, Lukas S. Stelzl, Bojan Zagrovic, Markus Zweckstetter

“…Abstract Eukaryotic gene regulation and pre-mRNA transcription depend on the carboxy-terminal domain (CTD) of RNA polymerase (Pol) II. Due to its highly repetitive, intrinsically disordered sequence, the CTD enables clustering and phase separation of Pol II. …”
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Baicalein and Baicalin Inhibit SARS-CoV-2 RNA-Dependent-RNA Polymerase by Keivan Zandi, Katie Musall, Adrian Oo, Dongdong Cao, Bo Liang, Pouya Hassandarvish, Shuiyun Lan, Ryan L. Slack, Karen A. Kirby, Leda Bassit, Franck Amblard, Baek Kim, Sazaly AbuBakar, Stefan G. Sarafianos, Raymond F. Schinazi

“…Our data through cell-based and biochemical studies showed that both compounds act as SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) inhibitors directly and inhibit the activity of the SARS-CoV-2 RdRp, but baicalein was more potent. …”
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Structural and Functional Basis of the Fidelity of Nucleotide Selection by Flavivirus RNA-Dependent RNA Polymerases by Barbara Selisko, Nicolas Papageorgiou, François Ferron, Bruno Canard

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A remodeled RNA polymerase II complex catalyzing viroid RNA-templated transcription. by Shachinthaka D Dissanayaka Mudiyanselage, Junfei Ma, Tibor Pechan, Olga Pechanova, Bin Liu, Ying Wang

“…It is well-known that nuclear-replicating viroids exploit host DNA-dependent RNA polymerase II (Pol II) activity for transcription from circular RNA genome to minus-strand intermediates, a classic example illustrating the intrinsic RNA-dependent RNA polymerase activity of Pol II. …”
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Structural basis of the mycobacterial stress-response RNA polymerase auto-inhibition via oligomerization by Zakia Morichaud, Stefano Trapani, Rishi K. Vishwakarma, Laurent Chaloin, Corinne Lionne, Joséphine Lai-Kee-Him, Patrick Bron, Konstantin Brodolin

“…Here, authors reported high-order structure of RNA polymerase and its role in regulation of gene expression in pathogenic bacterium.…”
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Revisiting Viral RNA-Dependent RNA Polymerases: Insights from Recent Structural Studies by Kavitha Ramaswamy, Mariya Rashid, Selvarajan Ramasamy, Tamilselvan Jayavelu, Sangita Venkataraman

“…RNA-dependent RNA polymerases (RdRPs) represent a distinctive yet versatile class of nucleic acid polymerases encoded by RNA viruses for the replication and transcription of their genome. …”
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Common changes in global gene expression induced by RNA polymerase inhibitors in Shigella flexneri. by Hua Fu, Liguo Liu, Xiaobing Zhang, Yafang Zhu, Lina Zhao, Junping Peng, Hongxuan He, Qi Jin

“…Here, the common response of Shigella flexneri to two inhibitors of RNA polymerase was examined using gene expression profiling. …”
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RNA Polymerase II cluster dynamics predict mRNA output in living cells by English, Brian P, Grimm, Jonathan B, Lavis, Luke D, Lionnet, Timothée, Cho, Won-ki, Jayanth, Namrata, Andrews, James Owen, Conway, William E., Spille, Jan Hendrik, Cisse, Ibrahim I, Inoue, Takuma

“…We developed a live-cell super-resolution approach to uncover the correlation between mRNA synthesis and the dynamics of RNA Polymerase II (Pol II) clusters at a gene locus. For endogenous β-actin genes in mouse embryonic fibroblasts, we observe that short-lived (~8 s) Pol II clusters correlate with basal mRNA output. …”
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