-
201
Decreasing mitochondrial RNA polymerase activity reverses biased inheritance of hypersuppressive mtDNA
Published 2021“…This suppression required <jats:italic>PET127</jats:italic> binding to the mitochondrial RNA polymerase <jats:italic>RPO41</jats:italic> but not <jats:italic>PET127</jats:italic> exonuclease activity. …”
Get full text
Article -
202
-
203
A 'resource allocator' for transcription based on a highly fragmented T7 RNA polymerase
Published 2014“…Synthetic genetic systems share resources with the host, including machinery for transcription and translation. Phage RNA polymerases (RNAPs) decouple transcription from the host and generate high expression. …”
Get full text
Get full text
Get full text
Article -
204
Mapping inhibitory sites on the RNA polymerase of the 1918 pandemic influenza virus using nanobodies
Published 2022“…Central to the replication cycle of influenza viruses is the viral RNA-dependent RNA polymerase which transcribes and replicates the viral RNA genome. …”
Journal article -
205
Connections between RNA Polymerase II transcriptional regulation, nucleosome arrangement and DNA damage
Published 2017Subjects:Thesis -
206
Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I.
Published 2010“…Transcription termination by RNA polymerase I in Saccharomyces cerevisiae is mediated by a 'torpedo' mechanism: co-transcriptional RNA cleavage by Rnt1 at the ribosomal DNA 3'-region generates a 5'-end that is recognized by the 5'-3' exonuclease Rat1; this degrades the downstream transcript and eventually causes termination. …”
Journal article -
207
Messenger RNAs that are not synthesized by RNA polymerase II can be 3' end cleaved and polyadenylated.
Published 2000“…The poly(A) tail of influenza virus mRNAs is synthesized by the viral RNA polymerase by reiterative copying of a U5-7 sequence near the 5' end of the viral RNA (vRNA) template. …”
Journal article -
208
The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Published 2004“…The RNA-dependent RNA polymerase of bacteriophage phi6 transcribes mRNA from the three segments of the dsRNA viral genome. …”
Journal article -
209
Transcriptional termination by RNA polymerase I requires the small subunit Rpa12p.
Published 2004“…We identify Rpa12p of RNA polymerase I (Pol I) as a termination factor. Combined analyses using transcription run-on, electron microscopy-visualized chromatin spreading and RT-PCR have been applied to the rRNA-encoding genes of Saccharomyces cerevisiae. …”
Journal article -
210
Characterizing Influenza a RNA Polymerase - Promoter Interaction using Ensemble Fluorescence Spectroscopy
Published 2013Conference item -
211
RNA Polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation
Published 2023“…The controlled release of promoter-proximal paused RNA polymerase II (Pol II) into productive elongation is a major step in gene regulation. …”
Internet publication -
212
Association of the influenza virus RNA polymerase subunit PB2 with the host chaperonin CCT.
Published 2010“…The RNA polymerase of influenza A virus is a host range determinant and virulence factor. …”
Journal article -
213
The RNA polymerase of influenza a virus is stabilized by interaction with its viral RNA promoter.
Published 2002“…The RNA polymerase of the influenza virus is responsible for the transcription and replication of the segmented RNA viral genome during infection of host cells. …”
Journal article -
214
Differential effects of pre-mRNA splicing inhibitors on RNA polymerase II transcription
Published 2023“…The production of eukaryotic mRNA requires transcription by RNA polymerase (pol) II and co-transcriptional processing, including capping, splicing, and cleavage and polyadenylation (CPA). …”
Internet publication -
215
BRCA1 cooperates with NUFIP and P-TEFb to activate transcription by RNA polymerase II.
Published 2004“…The tumor suppressor gene product BRCA1 is a component of the RNA polymerase II (pol II) holoenzyme that is involved, through binding to various regulatory proteins, in either activation or repression of transcription. …”
Journal article -
216
The PB2 subunit of the influenza A virus RNA polymerase is imported into the mitochondrial matrix
Published 2016“…The PB2 subunit of the RNA polymerase complex of seasonal human influenza A viruses has been shown to localise to the mitochondria. …”
Journal article -
217
RNA polymerase II pausing temporally coordinates cell cycle progression and erythroid differentiation.
Published 2023“…Controlled release of promoter-proximal paused RNA polymerase II (RNA Pol II) is crucial for gene regulation. …”
Journal article -
218
Establishment of a fluorescent reporter of RNA-polymerase II activity to identify dormant cells
Published 2021“…Here, we develop a live cell ratiometric fluorescent Optical Stem Cell Activity Reporter (OSCAR) based on the observation that phosphorylation of RNA Polymerase II (RNApII), a hallmark of active mRNA transcription elongation, is largely absent in dormant stem cells from multiple lineages. …”
Journal article -
219
Horizontally acquired AT-rich genes in Escherichia coli cause toxicity by sequestering RNA polymerase
Published 2017“…Left unchecked, this causes titration of RNA polymerase and a global downshift in host gene expression. …”
Journal article -
220
Photobleaching reveals complex effects of inhibitors on transcribing RNA polymerase II in living cells.
Published 2007“…RNA polymerase II transcribes most eukaryotic genes. Photobleaching studies have revealed that living Chinese hamster ovary cells expressing the catalytic subunit of the polymerase tagged with the green fluorescent protein contain a large rapidly exchanging pool of enzyme, plus a smaller engaged fraction; genetic complementation shows this tagged polymerase to be fully functional. …”
Journal article