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301
How Single-Molecule Localization Microscopy Expanded Our Mechanistic Understanding of RNA Polymerase II Transcription
Published 2021-06-01“…Although the spatial organization and dynamics of RNA polymerase II (RNAPII) transcription machinery have fundamental functional consequences for gene expression, its detailed studies have been abrogated by the limits of classical light microscopy for a long time. …”
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302
Conserved Curvature of RNA Polymerase I Core Promoter Beyond rRNA Genes: The Case of the Tritryps
Published 2015-12-01Subjects: Get full text
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303
Genome‐wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling
Published 2013-01-01“…Correlative analysis of FOXO3 and RNA polymerase II ChIP‐seq profiles demonstrates FOXO3 to act as a transcriptional activator. …”
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304
Reporter-ChIP-nexus reveals strong contribution of the Drosophila initiator sequence to RNA polymerase pausing
Published 2019-04-01Subjects: “…RNA polymerase II pausing…”
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305
Current understanding of nucleoside analogs inhibiting the SARS-CoV-2 RNA-dependent RNA polymerase
Published 2023-01-01Subjects: Get full text
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306
RNA polymerase II stalling at pre-mRNA splice sites is enforced by ubiquitination of the catalytic subunit
Published 2017-10-01Subjects: Get full text
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307
Bridged filaments of histone-like nucleoid structuring protein pause RNA polymerase and aid termination in bacteria
Published 2015-01-01“…In this study, we report that bridged H-NS filaments strongly increase pausing by E. coli RNA polymerase at a subset of pause sites with high potential for backtracking. …”
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308
Targeting RNA Polymerase I Transcription Activity in Osteosarcoma: Pre-Clinical Molecular and Animal Treatment Studies
Published 2023-04-01Subjects: Get full text
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309
In silico screening of drug inhibitors of SARS-CoV-2 RNA-dependent RNA polymerase target
Published 2022-03-01Subjects: Get full text
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310
Characterization of RNA polymerase II trigger loop mutations using molecular dynamics simulations and machine learning.
Published 2023-03-01“…Catalysis and fidelity of multisubunit RNA polymerases rely on a highly conserved active site domain called the trigger loop (TL), which achieves roles in transcription through conformational changes and interaction with NTP substrates. …”
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311
Hmo1 Promotes Efficient Transcription Elongation by RNA Polymerase I in <i>Saccharomyces cerevisiae</i>
Published 2024-02-01Subjects: “…RNA polymerase I…”
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312
What is the role of motif D in the nucleotide incorporation catalyzed by the RNA-dependent RNA polymerase from poliovirus?
Published 2012-01-01“…Poliovirus (PV) is a well-characterized RNA virus, and the RNA-dependent RNA polymerase (RdRp) from PV (3D(pol)) has been widely employed as an important model for understanding the structure-function relationships of RNA and DNA polymerases. …”
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313
Fibrillarin methylates H2A in RNA polymerase I trans-active promoters in Brassica oleracea
Published 2015-11-01Subjects: Get full text
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314
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HIV Tat controls RNA Polymerase II and the epigenetic landscape to transcriptionally reprogram target immune cells
Published 2015-10-01Subjects: Get full text
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316
Transcription by the Three RNA Polymerases under the Control of the TOR Signaling Pathway in <i>Saccharomyces cerevisiae</i>
Published 2023-04-01Subjects: Get full text
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317
Identification of a New Drug Binding Site in the RNA-Dependent-RNA-Polymerase (RdRp) Domain
Published 2023-10-01Subjects: “…RNA-dependent-RNA-polymerase (RdRp)…”
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318
RNA Polymerase II “Pause” Prepares Promoters for Upcoming Transcription during <i>Drosophila</i> Development
Published 2022-09-01Subjects: Get full text
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319
Polyphenols as Potential Inhibitors of SARS-CoV-2 RNA Dependent RNA Polymerase (RdRp)
Published 2021-12-01“…Here we applied computational approaches to examine if some polyphenols can also inhibit RNA polymerase (RdRp) in SARS-CoV-2, and we identified some better candidates than remdesivir, the FDA-approved drug against RdRp, in terms of estimated binding affinities. …”
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320
Defining the Influence of the A12.2 Subunit on Transcription Elongation and Termination by RNA Polymerase I In Vivo
Published 2021-11-01Subjects: “…RNA polymerase I…”
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