The POLR3G Subunit of Human RNA Polymerase III Regulates Tumorigenesis and Metastasis in Triple-Negative Breast Cancer by Wiebke Lautré, Elodie Richard, Jean-Paul Feugeas, Hélène Dumay-Odelot, Martin Teichmann

Subjects: “…RNA polymerase III…”
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Predictive Potential of RNA Polymerase B (II) Subunit 1 (RPB1) Cytoplasmic Aggregation for Neoadjuvant Chemotherapy Failure by Bence Nagy-Mikó, Orsolya Németh-Szatmári, Réka Faragó-Mészáros, Aliz Csókási, Bence Bognár, Nóra Ördög, Barbara N. Borsos, Hajnalka Majoros, Zsuzsanna Ujfaludi, Orsolya Oláh-Németh, Aliz Nikolényi, Ágnes Dobi, Renáta Kószó, Dóra Sántha, György Lázár, Zsolt Simonka, Attila Paszt, Katalin Ormándi, Tibor Pankotai, Imre M. Boros, Zoltán Villányi, András Vörös

“…As an indicator for such an event, we followed the cytoplasmic aggregation of RPB1, the aggregation-prone largest subunit of RNA polymerase II, in biopsy samples taken from patients with invasive carcinoma of no special type. …”
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The effects of SN Ps in the regions of positioning RNA polymerase II on the TBP/promoter affinity in the genes of human circadian clock by O. A. Podkolodnaya, D. A. Rasskazov, N. L. Podkolodnyy, N. N. Podkolodnaya, V. V. Suslov, L. K. Savinkova, P. M. Ponomarenko, M. P. Ponomarenko

“…The SNP_TATA_Comparator web service was used for prediction of the effect of SNPs in the regions of positioning of RNA polymerase II on the dissociation constant for TBP / promoter. …”
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TOX4 facilitates promoter-proximal pausing and C-terminal domain dephosphorylation of RNA polymerase II in human cells by Ziling Liu, Aiwei Wu, Zhen Wu, Talang Wang, Yixuan Pan, Bing Li, Xumin Zhang, Ming Yu

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Lsh mediated RNA polymerase II stalling at HoxC6 and HoxC8 involves DNA methylation. by Yongguang Tao, Sichuan Xi, Victorino Briones, Kathrin Muegge

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RNA polymerase I promoter and splice acceptor site recognition affect gene expression in non-pathogenic Leishmania species by Tereza Cristina Orlando, Mário Gustavo Mayer, David A Campbell, Nancy R Sturm, Lucile Maria Floeter-Winter

“…We have evaluated heterologous expression systems using vectors with two different polypyrimidine tracts in the splice acceptor site by measuring a reporter gene transcribed from L. tarentolae RNA polymerase I promoter. Our data indicate that the efficiency of chloramphenicol acetyl transferase expression changed drastically with homologous or heterologous sequences, depending on the polypyrimidine tract used in the construct and differences in size and/or distance from the AG dinucleotide. …”
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Identification of novel mutations in RNA-dependent RNA polymerases of SARS-CoV-2 and their implications on its protein structure by Gyanendra Bahadur Chand, Atanu Banerjee, Gajendra Kumar Azad

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Genetic and structural study of DNA-directed RNA polymerase II of Trypanosoma brucei, towards the designing of novel antiparasitic agents by Louis Papageorgiou, Vasileios Megalooikonomou, Dimitrios Vlachakis

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Correction: Ago1 Interacts with RNA Polymerase II and Binds to the Promoters of Actively Transcribed Genes in Human Cancer Cells

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Oral GS-441524 derivatives: Next-generation inhibitors of SARS‐CoV‐2 RNA‐dependent RNA polymerase by Zhonglei Wang, Zhonglei Wang, Liyan Yang, Xian-qing Song

“…GS-441524, an RNA‐dependent RNA polymerase (RdRp) inhibitor, is a 1′-CN-substituted adenine C-nucleoside analog with broad-spectrum antiviral activity. …”
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CaRDR1, an RNA-Dependent RNA Polymerase Plays a Positive Role in Pepper Resistance against TMV by Lei Qin, Ning Mo, Yang Zhang, Tayeb Muhammad, Guiye Zhao, Yan Zhang, Yan Liang

“…RNA silencing functions as a major natural antiviral defense mechanism in plants. RNA-dependent RNA polymerases (RDRs) that catalyze the synthesis of double-stranded RNAs, are considered as a fundamental element in RNA silencing pathways. …”
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G-Quadruplex in Gene Encoding Large Subunit of Plant RNA Polymerase II: A Billion-Year-Old Story by Adriana Volná, Martin Bartas, Václav Karlický, Jakub Nezval, Kristýna Kundrátová, Petr Pečinka, Vladimír Špunda, Jiří Červeň

“…Here, we conducted a bioinformatic study and performed a complex circular dichroism measurement to identify a stable G-quadruplex in the gene <i>RPB1</i>, coding for the RNA polymerase II large subunit. We found that this G-quadruplex-forming locus is highly evolutionarily conserved amongst plants sensu lato (Archaeplastida) that share a common ancestor more than one billion years old. …”
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A dual role for H2A.Z.1 in modulating the dynamics of RNA polymerase II initiation and elongation by Mylonas, Constantine, Lee, Choongman, Auld, Alexander L, Cisse, Ibrahim I, Boyer, Laurie A

“…RNA polymerase II (RNAPII) pausing immediately downstream of the transcription start site is a critical rate-limiting step for the expression of most metazoan genes. …”
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High-resolution RNA allelotyping along the inactive X chromosome: evidence of RNA polymerase III in regulating chromatin configuration by Hong, Ru, Lin, Bingqing, Lu, Xinyi, Lai, Lan-Tian, Chen, Xin, Sanyal, Amartya, Ng, Huck-Hui, Zhang, Kun, Zhang, Li-Feng

“…SINE is a class of retrotransposon transcribed by RNA polymerase III (Pol III). Intriguingly, a significant fraction of Pol III transcription from non-coding regions is not subjected to Xist-mediated transcriptional silencing. …”
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Polymorphism in Tmem132d regulates expression and anxiety-related behavior through binding of RNA polymerase II complex by Naik, Roshan R., Sotnikov, Sergey V., Diepold, Rebekka P., Iurato, Stella, Markt, Patrick O., Bultmann, Andrea, Brehm, Nadine, Mattheus, Tobias, Lutz, Beat, Erhardt, Angelika, Binder, Elisabeth B., Schmidt, Ulrike, Holsboer, Florian, Landgraf, Rainer, Czibere, Ludwig

“…Furthermore, we found significantly higher binding of RNA polymerase II (POLR2A) to the proximal HAB-specific SNP (rs233264624) than the corresponding LAB locus in an oligonucleotide pull-down assay, suggesting increased transcription. …”
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HSV-1 ICP22 is a selective viral repressor of cellular RNA polymerase II-mediated transcription elongation by Isa, NF, Bensaude, O, Aziz, NC, Murphy, S

“…ICP22 inhibits phosphorylation of Ser2 of the RNA polymerase II (pol II) carboxyl-terminal domain (CTD) and productive elongation of pol II. …”

The PA subunit is required for efficient nuclear accumulation of the PB1 subunit of the influenza A virus RNA polymerase complex. by Fodor, E, Smith, M

“…The RNA genome of influenza virus is transcribed and replicated by the viral RNA polymerase complex in the cell nucleus. We have generated green fluorescent protein (GFP)-tagged polymerase subunits to study the assembly of the polymerase complex. …”

The RNA polymerase clamp interconverts dynamically among three states and is stabilized in a partly closed state by ppGpp by Duchi, D, Mazumder, A, Malinen, A, Ebright, R, Kapanidis, A

“… <p style="text-align:justify;"> RNA polymerase (RNAP) contains a mobile structural module, the ‘clamp,’ that forms one wall of the RNAP active-center cleft and that has been linked to crucial aspects of the transcription cycle, including promoter melting, transcription elongation complex stability, transcription pausing, and transcription termination. …”

Translocation of sigma(70) with RNA polymerase during transcription: fluorescence resonance energy transfer assay for movement relative to DNA. by Mukhopadhyay, J, Kapanidis, A, Mekler, V, Kortkhonjia, E, Ebright, Y, Ebright, R

“…Using fluorescence resonance energy transfer, we show that, in the majority of transcription complexes, sigma(70) is not released from RNA polymerase upon transition from initiation to elongation, but, instead, remains associated with RNA polymerase and translocates with RNA polymerase. …”

The C-terminal priming domain is strongly associated with the main body of bacteriophage φ6 RNA-dependent RNA polymerase by Sarin, L, Wright, S, Chen, Q, Degerth, L, Stuart, D, Grimes, J, Bamford, D, Poranen, M

“…Double-stranded RNA viruses encode a single protein species containing RNA-dependent RNA polymerase (RdRP) motifs. This protein is responsible for RNA transcription and replication. …”