A single amino acid mutation in the PA subunit of the influenza virus RNA polymerase promotes the generation of defective interfering RNAs. by Fodor, E, Mingay, L, Crow, M, Deng, T, Brownlee, G

“…An R638A mutation of the polymerase acidic protein (PA) subunit of the RNA polymerase of influenza A/WSN/33 virus results in severe attenuation of viral growth in cell culture by promoting the synthesis of defective interfering RNAs. …”

A mutation in the largest (catalytic) subunit of RNA polymerase II and its relation to the arrest of the cell cycle in G(1) phase. by Sugaya, K, Sasanuma, S, Cook, P, Mita, K

“…Transcriptional activity of RNA polymerase II is modulated during the cell cycle. …”

New core promoter element in RNA polymerase II-dependent transcription: sequence-specific DNA binding by transcription factor IIB. by Lagrange, T, Kapanidis, A, Tang, H, Reinberg, D, Ebright, R

Development of a T7 RNA polymerase expressing cell line using lentivirus vectors for the recovery of recombinant Newcastle disease virus by Yeong, Ming Yue, Cheow, Pheik Sheen, Abdullah, Syahril, Song, Adelene Ai Lian, Lei, Janet Rossmann, Tan, Tiong Kit, Yusoff, Khatijah, Chia, Suet Lin

“…The development of a T7 RNA polymerase (T7 RNAP) expressing cell line i.e. BSR T7/5 cells marks an improvement of reverse genetics for the recovery of recombinant Newcastle disease virus (rNDV). …”
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The elemental mechanism of transcriptional pausing by Jason Saba, Xien Yu Chua, Tatiana V Mishanina, Dhananjaya Nayak, Tricia A Windgassen, Rachel Anne Mooney, Robert Landick

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Witnessing the structural evolution of an RNA enzyme by Xavier Portillo, Yu-Ting Huang, Ronald R Breaker, David P Horning, Gerald F Joyce

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NeoRdRp2 with improved seed data, annotations, and scoring by Shoichi Sakaguchi, Takashi Nakano, So Nakagawa, So Nakagawa, So Nakagawa

Subjects: “…RNA-dependent RNA polymerase…”
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Subtle structural differences of nucleotide analogs may impact SARS-CoV-2 RNA-dependent RNA polymerase and exoribonuclease activity by Abraham Madariaga-Mazón, José J. Naveja, Arturo Becerra, José Alberto Campillo-Balderas, Ricardo Hernández-Morales, Rodrigo Jácome, Antonio Lazcano, Karina Martinez-Mayorga

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Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle by Gabriele Büchel, Anne Carstensen, Ka-Yan Mak, Isabelle Roeschert, Eoin Leen, Olga Sumara, Julia Hofstetter, Steffi Herold, Jacqueline Kalb, Apoorva Baluapuri, Evon Poon, Colin Kwok, Louis Chesler, Hans Michael Maric, David S. Rickman, Elmar Wolf, Richard Bayliss, Susanne Walz, Martin Eilers

“…Summary: MYC proteins bind globally to active promoters and promote transcriptional elongation by RNA polymerase II (Pol II). To identify effector proteins that mediate this function, we performed mass spectrometry on N-MYC complexes in neuroblastoma cells. …”
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Covalent Inhibitors from Saudi Medicinal Plants Target RNA-Dependent RNA Polymerase (RdRp) of SARS-CoV-2 by Ahmed H. Bakheit, Quaiser Saquib, Sarfaraz Ahmed, Sabiha M. Ansari, Abdullah M. Al-Salem, Abdulaziz A. Al-Khedhairy

“…We computationally evaluated the inhibition of RNA-dependent RNA polymerase (RdRp) by compounds <b>1</b>–<b>10</b>. …”
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Correction: Rad26, the Transcription-Coupled Repair Factor in Yeast, Is Required for Removal of Stalled RNA Polymerase-II following UV Irradiation

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Molecular and Structural Aspects of Clinically Relevant Mutations of SARS-CoV-2 RNA-Dependent RNA Polymerase in Remdesivir-Treated Patients by Carmen Gratteri, Francesca Alessandra Ambrosio, Antonio Lupia, Federica Moraca, Bruno Catalanotti, Giosuè Costa, Maria Bellocchi, Luca Carioti, Romina Salpini, Francesca Ceccherini-Silberstein, Simone La Frazia, Vincenzo Malagnino, Loredana Sarmati, Valentina Svicher, Sharon Bryant, Anna Artese, Stefano Alcaro

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Correction: Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD

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SETD5 regulates the OGT-catalyzed O-GlcNAcylation of RNA polymerase II, which is involved in the stemness of colorectal cancer cells by Hye In Cho, Sora Jo, Min Seong Kim, Han Byeol Kim, Xingzhe Liu, Yanhua Xuan, Jin Won Cho, Yeun Kyu Jang

“…Abstract The dosage-dependent recruitment of RNA polymerase II (Pol II) at the promoters of genes related to neurodevelopment and stem cell maintenance is required for transcription by the fine-tuned expression of SET-domain-containing protein 5 (SETD5). …”
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Evidence Supporting That RNA Polymerase II Catalyzes De Novo Transcription Using Potato Spindle Tuber Viroid Circular RNA Templates by Shachinthaka D. Dissanayaka Mudiyanselage, Ying Wang

Subjects: “…RNA Polymerase II…”
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Fludarabine, a Potential DNA-Dependent RNA Polymerase Inhibitor, as a Prospective Drug against Monkeypox Virus: A Computational Approach by Hisham N. Altayb

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SEQUENCE ANALYSIS OF HOT SPOT REGIONS OF SPIKE AND RNA‑DEPENDENT‑RNA POLYMERASE (RDRP) GENES OF SARS-COV-2 IN KERMAN, IRAN by Nasir, Ramin, Amin, Jamal

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Pharmacological Therapeutics Targeting RNA-Dependent RNA Polymerase, Proteinase and Spike Protein: From Mechanistic Studies to Clinical Trials for COVID-19 by Jiansheng Huang, Wenliang Song, Hui Huang, Quancai Sun

Subjects: “…RNA-dependent RNA polymerase…”
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The Functional Implications of Broad Spectrum Bioactive Compounds Targeting RNA-Dependent RNA Polymerase (RdRp) in the Context of the COVID-19 Pandemic by Brittany A. Comunale, Robin J. Larson, Erin Jackson-Ward, Aditi Singh, Frances L. Koback, Lilly D. Engineer

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N-Terminal Tails of Histones H2A and H2B Differentially Affect Transcription by RNA Polymerase II In Vitro by Han-Wen Chang, Alexey V. Feofanov, Alexander V. Lyubitelev, Grigory A. Armeev, Elena Y. Kotova, Fu-Kai Hsieh, Mikhail P. Kirpichnikov, Alexey K. Shaytan, Vasily M. Studitsky

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