Promoter-Bound Full-Length Intronic Circular RNAs-RNA Polymerase II Complexes Regulate Gene Expression in the Human Parasite <i>Entamoeba histolytica</i> by Jesús Alberto García-Lerena, Gretter González-Blanco, Odila Saucedo-Cárdenas, Jesús Valdés

“…Here, we provide novel evidence of the role of flicRNAs in gene expression regulation in cis, apparently in a widespread fashion, as an element bound to the RNA polymerase II transcription initiation complex, in <i>E. histolytica</i>.…”
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RNA sensor response in HeLa cells for transfected mRNAs prepared in vitro by SP6 and HiT7 RNA polymerases: A comparative study by Siranjeevi Nagaraj, Anna Stankiewicz-Drogon, Edward Darzynkiewicz, Edward Darzynkiewicz, Renata Grzela, Renata Grzela

Subjects: “…RNA polymerase…”
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A viral RNA-dependent RNA polymerase inhibitor VV116 broadly inhibits human coronaviruses and has synergistic potency with 3CLpro inhibitor nirmatrelvir by Yumin Zhang, Yuan Sun, Yuanchao Xie, Weijuan Shang, Zhen Wang, Hualiang Jiang, Jingshan Shen, Gengfu Xiao, Leike Zhang

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Flavonoid glycosides and their putative human metabolites as potential inhibitors of the SARS-CoV-2 main protease (Mpro) and RNA-dependent RNA polymerase (RdRp) by Felipe Moura A da Silva, Katia Pacheco A da Silva, Luiz Paulo M de Oliveira, Emmanoel V Costa, Hector HF Koolen, Maria Lúcia B Pinheiro, Antonia Queiroz L de Souza, Afonso Duarte L de Souza

“…Among these proteins, 3-chymotrypsin-like cysteine protease (3CLpro), also named main protease, and the RNA-dependent RNA polymerase (RdRp), have been identified as fundamental targets due to its importance in the viral replication stages. …”
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Investigating non-nucleoside inhibitors targeting the Zika virus non-structural protein 5 (NS5) RNA-dependent RNA polymerase (RdRp) domain by Zhang, Denzel Xugeng

“…Here, the RNA dependent RNA Polymerase (RdRP) of Zika Virus was purified based on previously established protocols. …”
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Solid phase synthesis of 5'-diphosphorylated oligoribonucleotides and their conversion to capped m7Gppp-oligoribonucleotides for use as primers for influenza A virus RNA polymerase in vitro. by Brownlee, G, Fodor, E, Pritlove, D, Gould, K, Dalluge, J

“…Radiolabelled capped oligoribonucleotides acted as primers for the influenza A virus RNA polymerase in vitro. The solid phase method described here should also allow the addition of 5'-diphosphates to synthetic oligodeoxyribonucleotides and be capable automation.…”

The N-terminal region of the PA subunit of the RNA polymerase of influenza A/HongKong/156/97 (H5N1) influences promoter binding. by Kashiwagi, T, Leung, B, Deng, T, Chen, H, Brownlee, G

“… BACKGROUND: The RNA polymerase of influenza virus is a heterotrimeric complex of PB1, PB2 and PA subunits which cooperate in the transcription and replication of the viral genome. …”

Different de novo initiation strategies are used by influenza virus RNA polymerase on its cRNA and viral RNA promoters during viral RNA replication. by Deng, T, Vreede, F, Brownlee, G

“…Thus, influenza virus RNA polymerase uses different initiation strategies on its cRNA and vRNA promoters. …”

A cluster of conserved basic amino acids near the C-terminus of the PB1 subunit of the influenza virus RNA polymerase is involved in the regulation of viral transcription. by Kerry, P, Willsher, N, Fodor, E

“…Synthesis of influenza virus mRNA by the viral RNA polymerase complex is primed by capped RNA fragments generated by endonuclease cleavage of host pre-mRNA by the polymerase subunit PB1. …”

Dominant CD4-dependent RNA-dependent RNA polymerase-specific T-cell responses in children acutely infected with human enterovirus 71 and healthy adult controls. by Dang, S, Gao, N, Li, Y, Li, M, Wang, X, Jia, X, Zhai, S, Zhang, X, Liu, J, Deng, H, Dong, T

“…In this study, we performed a comprehensive ex vivo interferon-γ ELISPOT analysis in 31 children infected with EV71 as well as in 40 healthy adult controls of the CD4(+) and CD8(+) T-cell responses to overlapping peptides spanning the VP1 structural protein and RNA-dependent RNA polymerase (RdRp) non-structural protein. EV71-specific CD4 T-cell responses were detected in most of the acute patients and were mostly CD4-dependent RdRp-specific responses. …”

Development of a T7-Independent MARV Minigenome System by Bert Vanmechelen, Joren Stroobants, Kurt Vermeire, Piet Maes

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Investigating the role of RNA structures in transcriptional pausing using in vitro assays and in silico analyses by Simon Jeanneau, Pierre-Étienne Jacques, Daniel A. Lafontaine

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Independent Inhibition of the Polymerase and Deubiquitinase Activities of the Crimean–Congo Hemorrhagic Fever Virus Full-Length L-Protein by Egor P. Tchesnokov, Ben A. Bailey-Elkin, Brian L. Mark, Matthias Götte

Subjects: “…RNA-dependent RNA polymerase…”
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Identification of SL addition trans-splicing acceptor sites in the internal transcribed spacer I region of pre-rRNA in Leishmania (Leishmania) amazonensis by Mario Gustavo Mayer, Lucile Maria Floeter-Winter

Subjects: “…RNA polymerase I…”
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Small Molecule RBI2 Disrupts Ribosome Biogenesis through Pre-rRNA Depletion by Catherine E. Scull, Guy Twa, Yinfeng Zhang, Naiheng J. Yang, Robert N. Hunter, Corinne E. Augelli-Szafran, David A. Schneider

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Genome-wide mapping of the distribution of CarD, RNAP σA, and RNAP β on the Mycobacterium smegmatis chromosome using chromatin immunoprecipitation sequencing by Robert Landick, Azra Krek, Michael S. Glickman, Nicholas D. Socci, Christina L. Stallings

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RNA Pol II Assembly Affects ncRNA Expression by Ana I. Garrido-Godino, Ishaan Gupta, Vicent Pelechano, Francisco Navarro

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Promoting the production of challenging proteins via induced expression in CHO cells and modified cell-free lysates harboring T7 RNA polymerase and mutant eIF2α by Jeffrey L. Schloßhauer, Lena Tholen, Alexander Körner, Stefan Kubick, Sofia Chatzopoulou, Anja Hönow, Anne Zemella

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Correction: The RNA Polymerase PB2 Subunit of Influenza A/HongKong/156/1997 (H5N1) Restrict the Replication of Reassortant Ribonucleoprotein Complexes

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Structural Motifs and Spatial Structures of Helicase (NS3) and RNA-dependent RNA-polymerase (NS5) of a Flavi-like Kindia tick virus (unclassified Flaviviridae) by A. A. Gladysheva, A. V. Gladysheva, V. A. Ternovoi, V. B. Loktev

“…The methyltransferase and RNA-dependent RNA-polymerase domains were found in the NS5 KITV. The latter was represented by fingers, palm and thumb subdomains, and motifs A-F. …”
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