How to Shut Down Transcription in Archaea during Virus Infection by Simona Pilotto, Finn Werner

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The impact of drug resistance on Mycobacterium tuberculosis physiology: what can we learn from rifampicin? by Anastasia Koch, Valerie Mizrahi, Digby F Warner

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Rolling circle transcription of ribozymes from promoterless single-stranded DNA nanocircles in mammalian cells [Ribozimlerin, promotorsuz tek-iplikli DNA çemberlerinin rolling circ... by Attila A. Seyhan

Subjects: “…T7 RNA polymerase…”
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Venezuelan Equine Encephalitis Virus V3526 Vaccine RNA-Dependent RNA Polymerase Mutants Increase Vaccine Safety Through Restricted Tissue Tropism in a Mouse Model by Clint A. Haines, Rafael K. Campos, Sasha R. Azar, K. Lane Warmbrod, Tiffany F. Kautz, Naomi L. Forrester, Shannan L. Rossi

“…A previous attempt to improve the TC-83 vaccine focused on further attenuating the vaccine by adding mutations that alter the error-incorporation rate of the RNA-dependent RNA polymerase (RdRp). The research herein examined the effects of these RdRp mutations in V3526 by cloning the 3X and 4X strains, assessing vaccine efficacy against challenge in adult female CD-1 mice, examining neutralizing-antibody titers, investigating vaccine tissue tropism, and testing the stability of the mutant strains. …”
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Discovery of SARS-CoV-2 RNA-dependent-RNA-polymerase (RdRp) Inhibitor from Sambiloto (Andrographis paniculata) Based on Molecular Docking and ADMET Prediction Approach by Dina Ahsana, Rizki Rahmadi Pratama, Alfisyahriatunnida Meily, Andika

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Favipiravir Analogues as Inhibitors of SARS-CoV-2 RNA-Dependent RNA Polymerase, Combined Quantum Chemical Modeling, Quantitative Structure–Property Relationship, and Molecular Docking Study by Magdalena Latosińska, Jolanta Natalia Latosińska

“…We hypothesized that analogues of favipiravir (FVP), an inhibitor of RNA-dependent RNA polymerase (RdRp), could provide more effective nucleic acid recognition and binding processes while reducing side effects such as cardiotoxicity, hepatotoxicity, teratogenicity, and embryotoxicity. …”
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Antiviral activities of olive oil apigenin and taxifolin against SARS-CoV-2 RNA-dependent RNA polymerase (RdRP): In silico, pharmacokinetic, ADMET, and in-vitro approaches by Samy Selim, Mha Albqmi, Awadh Alanazi, Yasir Alruwaili, Mohammad M. Al-Sanea, Taghreed S. Alnusaire, Mohammed S. Almuhayawi, Soad K. Al Jaouni, Shaimaa Hussein, Mona Warrad, Hamada AbdElgawad, Naglaa Elshafey, Mohamed E. Elnosary

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Critical Role for the Human Cytomegalovirus Major Immediate Early Proteins in Recruitment of RNA Polymerase II and H3K27Ac To an Enhancer-Like Element in OriLyt by Eleonora Forte, Ming Li, Fatma Ayaloglu Butun, Qiaolin Hu, Eva Maria Borst, Matthew J. Schipma, Andrea Piunti, Ali Shilatifard, Scott S. Terhune, Michael Abecassis, Jeffery L. Meier, Mary Hummel

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Modulation of Expression of PVY^NTN RNA-Dependent RNA Polymerase (NIb) and Heat Shock Cognate Host Protein HSC70 in Susceptible and Hypersensitive Potato Cultivars by Edmund Kozieł, Przemysław Surowiecki, Agnieszka Przewodowska, Józef J. Bujarski, Katarzyna Otulak-Kozieł

“…Its RNA-dependent RNA polymerase (RdRp) is known as nuclear inclusion protein b (NIb). …”
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Molecular and Structural Analysis of Specific Mutations from Saudi Isolates of SARS-CoV-2 RNA-Dependent RNA Polymerase and their Implications on Protein Structure and Drug–Protein Binding by Mubarak A. Alamri, Muhammad Tahir ul Qamar, Alhumaidi B. Alabbas, Safar M. Alqahtani, Manal A. Alossaimi, Sikandar Azam, Muhammad Harris Hashmi, Muhammad Shahid Riaz Rajoka

“…This study focuses on SARS-CoV2 RNA-dependent RNA polymerase (RdRp) mutations collected from Saudi Arabia and their impact on protein structure and function. …”
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The Association of Rpb4 with RNA Polymerase II Depends on CTD Ser5P Phosphatase Rtr1 and Influences mRNA Decay in <i>Saccharomyces cerevisiae</i> by Ana I. Garrido-Godino, Abel Cuevas-Bermúdez, Francisco Gutiérrez-Santiago, Maria del Carmen Mota-Trujillo, Francisco Navarro

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Discovering new potential inhibitors to SARS-CoV-2 RNA dependent RNA polymerase (RdRp) using high throughput virtual screening and molecular dynamics simulations by Dylan Brunt, Phillip M. Lakernick, Chun Wu

“…Abstract RNA dependent RNA polymerase (RdRp), is an essential in the RNA replication within the life cycle of the severely acute respiratory coronavirus-2 (SARS-CoV-2), causing the deadly respiratory induced sickness COVID-19. …”
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Ssn6 Interacts with Polar Tube Protein 2 and Transcriptional Repressor for RNA Polymerase II: Insight into Its Involvement in the Biological Process of Microsporidium <i>Nosema bombycis</i> by Runpeng Wang, Yong Chen, Sheng Xu, Erjun Wei, Ping He, Qiang Wang, Yiling Zhang, Xudong Tang, Zhongyuan Shen

Subjects: “…transcriptional repressor for RNA polymerase II…”
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(F)uridylylated Peptides Linked to VPg1 of Foot-and- Mouth Disease Virus (FMDV): Design, Synthesis and X-Ray Crystallography of the Complexes with FMDV RNA-Dependent RNA Polymerase by Sonia de Castro, Cristina Ferrer-Orta, Alberto Mills, Gloria Fernández-Cureses, Federico Gago, Nuria Verdaguer, María-José Camarasa

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Retraction: Wolbachia Transcription Elongation Factor "Wol GreA" Interacts with α2ββ'σ Subunits of RNA Polymerase through Its Dimeric C-Terminal Domain. by PLOS Neglected Tropical Diseases Editors

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Herpes Simplex Virus 1 (HSV-1) ICP22 protein directly interacts with cyclin-dependent kinase (CDK)9 to inhibit RNA polymerase II transcription elongation. by Zaborowska, J, Baumli, S, Laitem, C, O'Reilly, D, Thomas, P, O'Hare, P, Murphy, S

“…ICP22 is known to reduce the global level of serine (Ser)2 phosphorylation of the Tyr1Ser2Pro3Thr4Ser5Pro6Ser7 heptapeptide repeats comprising the carboxy-terminal domain (CTD) of the large subunit of RNA polymerase (pol) II. Accordingly, ICP22 is thought to associate with and inhibit the activity of the positive-transcription elongation factor b (P-TEFb) pol II CTD Ser2 kinase. …”

The cryo-EM structure of a 12-subunit variant of RNA polymerase I reveals dissociation of the A49-A34.5 heterodimer and rearrangement of subunit A12.2 by Lucas Tafur, Yashar Sadian, Jonas Hanske, Rene Wetzel, Felix Weis, Christoph W Müller

Subjects: “…RNA polymerase I…”
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The Catalytic Subunit of <i>Schizosaccharomyces pombe</i> CK2 (Cka1) Negatively Regulates RNA Polymerase II Transcription through Phosphorylation of Positive Cofactor 4 (PC4) by Diego A. Rojas, Fabiola Urbina, Aldo Solari, Edio Maldonado

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Genomic-Scale Interaction Involving Complementary Sequences in the Hepatitis C Virus 5′UTR Domain IIa and the RNA-Dependent RNA Polymerase Coding Region Promotes Efficient Virus Replication by Elodie Rance, Jerome E. Tanner, Caroline Alfieri

“…The data revealed that 5&prime;UTR nucleotides (nt) 95&ndash;110 in the internal ribosome entry site (IRES) domain IIa and matching nt sequence 8528&ndash;8543 located in the RNA-dependent RNA polymerase coding region NS5B, form a high-affinity RNA-RNA complex in vitro. …”
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Remdesivir MD Simulations Suggest a More Favourable Binding to SARS-CoV-2 RNA Dependent RNA Polymerase Mutant P323L Than Wild-Type by Anwar Mohammad, Fahd Al-Mulla, Dong-Qing Wei, Jehad Abubaker

Subjects: “…RNA dependent RNA polymerase…”
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