Showing 261 - 280 results of 1,970 for search '"RNA polymerase II"', query time: 0.42s Refine Results
  1. 261
  2. 262

    Numerous Post-translational Modifications of RNA Polymerase II Subunit Rpb4/7 Link Transcription to Post-transcriptional Mechanisms by Stephen Richard, Lital Gross, Jonathan Fischer, Keren Bendalak, Tamar Ziv, Shira Urim, Mordechai Choder

    Published 2021-01-01
    “…Summary: Rpb4/7 binds RNA polymerase II (RNA Pol II) transcripts co-transcriptionally and accompanies them throughout their lives. …”
    Get full text
    Article
  3. 263
  4. 264

    Mitotically heritable, RNA polymerase II-independent H3K4 dimethylation stimulates INO1 transcriptional memory by Bethany Sump, Donna G Brickner, Agustina D'Urso, Seo Hyun Kim, Jason H Brickner

    Published 2022-05-01
    “…This phenomenon, called epigenetic transcriptional memory, accelerates reactivation, and requires both changes in chromatin structure and recruitment of poised RNA polymerase II (RNAPII) to the promoter. Memory of inositol starvation in budding yeast involves a positive feedback loop between transcription factor-dependent interaction with the nuclear pore complex and histone H3 lysine 4 dimethylation (H3K4me2). …”
    Get full text
    Article
  5. 265

    The exosome component Rrp6 is required for RNA polymerase II termination at specific targets of the Nrd1-Nab3 pathway. by Melanie J Fox, Hongyu Gao, Whitney R Smith-Kinnaman, Yunlong Liu, Amber L Mosley

    Published 2015-01-01
    “…To determine the role of Rrp6 in NNS termination globally, we performed RNA sequencing (RNA-Seq) on total RNA and perform ChIP-exo analysis of RNA Polymerase II (RNAPII) localization. Deletion of RRP6 promotes hyper-elongation of multiple NNS-dependent transcripts resulting from both improperly processed 3' RNA ends and faulty transcript termination at specific target genes. …”
    Get full text
    Article
  6. 266

    A <it>Poisson </it>mixture model to identify changes in RNA polymerase II binding quantity using high-throughput sequencing technology by Liu Yunlong, Feng Weixing, Wu Jiejun, Nephew Kenneth P, Huang Tim HM, Li Lang

    Published 2008-09-01
    “…<p>Abstract</p> <p>We present a mixture model-based analysis for identifying differences in the distribution of RNA polymerase II (Pol II) in transcribed regions, measured using ChIP-seq (chromatin immunoprecipitation following massively parallel sequencing technology). …”
    Article
  7. 267

    Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD. by Tim Krischuns, Catherine Isel, Petra Drncova, Maria Lukarska, Alexander Pflug, Sylvain Paisant, Vincent Navratil, Stephen Cusack, Nadia Naffakh

    Published 2022-05-01
    “…Initiation of viral mRNA synthesis requires a direct association of FluPol with the host RNA polymerase II (RNAP II), in particular the repetitive C-terminal domain (CTD) of the major RNAP II subunit, to enable "cap-snatching" whereby 5'-capped oligomers derived from nascent RNAP II transcripts are pirated to prime viral transcription. …”
    Get full text
    Article
  8. 268

    Paired Box 9 (PAX9), the RNA polymerase II transcription factor, regulates human ribosome biogenesis and craniofacial development. by Katherine I Farley-Barnes, Engin Deniz, Maya M Overton, Mustafa K Khokha, Susan J Baserga

    Published 2020-08-01
    “…PAX9 functions as an RNA Polymerase II transcription factor to regulate the expression of proteins required for craniofacial and tooth development in humans. …”
    Get full text
    Article
  9. 269
  10. 270

    The transcription factor TFIIS zinc ribbon dipeptide Asp-Glu is critical for stimulation of elongation and RNA cleavage by RNA polymerase II by Jeon, Choon Ju, Yoon, Ho Sup, Agarwal, Kan

    Published 2012
    “…The eukaryotic transcription factor TFIIS enhances elongation and nascent transcript cleavage activities of RNA polymerase II in a stalled elongation complex. By site-directed mutagenesis, we have demonstrated that invariant residues Asp-261 and Glu-262 of the nucleic acid-binding TFIIS Zn ribbon are critical for stimulation of both elongation and RNA cleavage activities of RNA polymerase II. …”
    Get full text
    Get full text
    Conference Paper
  11. 271

    Binding to DNA of the RNA-polymerase II C-terminal domain allows discrimination between Cdk7 and Cdk9 phosphorylation by Lolli, G

    Published 2009
    “…The C-terminal domain (CTD) of RNA polymerase II regulates transcription through spatially and temporally coordinated events. …”
    Journal article
  12. 272

    A mutation in the largest (catalytic) subunit of RNA polymerase II and its relation to the arrest of the cell cycle in G(1) phase. by Sugaya, K, Sasanuma, S, Cook, P, Mita, K

    Published 2001
    “…Transcriptional activity of RNA polymerase II is modulated during the cell cycle. We previously identified a temperature-sensitive mutation in the largest (catalytic) subunit of RNA polymerase II (RPB1) that causes cell cycle arrest and genome instability. …”
    Journal article
  13. 273
  14. 274
  15. 275

    Association with Aurora-A Controls N-MYC-Dependent Promoter Escape and Pause Release of RNA Polymerase II during the Cell Cycle by Gabriele Büchel, Anne Carstensen, Ka-Yan Mak, Isabelle Roeschert, Eoin Leen, Olga Sumara, Julia Hofstetter, Steffi Herold, Jacqueline Kalb, Apoorva Baluapuri, Evon Poon, Colin Kwok, Louis Chesler, Hans Michael Maric, David S. Rickman, Elmar Wolf, Richard Bayliss, Susanne Walz, Martin Eilers

    Published 2017-12-01
    “…Summary: MYC proteins bind globally to active promoters and promote transcriptional elongation by RNA polymerase II (Pol II). To identify effector proteins that mediate this function, we performed mass spectrometry on N-MYC complexes in neuroblastoma cells. …”
    Get full text
    Article
  16. 276
  17. 277
  18. 278

    SETD5 regulates the OGT-catalyzed O-GlcNAcylation of RNA polymerase II, which is involved in the stemness of colorectal cancer cells by Hye In Cho, Sora Jo, Min Seong Kim, Han Byeol Kim, Xingzhe Liu, Yanhua Xuan, Jin Won Cho, Yeun Kyu Jang

    Published 2023-11-01
    “…Abstract The dosage-dependent recruitment of RNA polymerase II (Pol II) at the promoters of genes related to neurodevelopment and stem cell maintenance is required for transcription by the fine-tuned expression of SET-domain-containing protein 5 (SETD5). …”
    Get full text
    Article
  19. 279
  20. 280