Distinctive interactomes of RNA polymerase II phosphorylation during different stages of transcription by Rosamaria Y. Moreno, Kyle J. Juetten, Svetlana B. Panina, Jamie P. Butalewicz, Brendan M. Floyd, Mukesh Kumar Venkat Ramani, Edward M. Marcotte, Jennifer S. Brodbelt, Y. Jessie Zhang

“…Summary: During eukaryotic transcription, RNA polymerase II undergoes dynamic post-translational modifications on the C-terminal domain (CTD) of the largest subunit, generating an information-rich PTM landscape that transcriptional regulators bind. …”
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Correction: High-Resolution Phenotypic Landscape of the RNA Polymerase II Trigger Loop. by Chenxi Qiu, Olivia C Erinne, Jui M Dave, Ping Cui, Huiyan Jin, Nandhini Muthukrishnan, Leung K Tang, Sabareesh Ganesh Babu, Kenny C Lam, Paul J Vandeventer, Ralf Strohner, Jan Van den Brulle, Sing-Hoi Sze, Craig D Kaplan

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Extragenic accumulation of RNA polymerase II enhances transcription by RNA polymerase III. by Imke Listerman, Anita S Bledau, Inna Grishina, Karla M Neugebauer

“…Recent genomic data indicate that RNA polymerase II (Pol II) function extends beyond conventional transcription of primarily protein-coding genes. …”
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Structural heterogeneity in the intrinsically disordered RNA polymerase II C-terminal domain by Bede Portz, Feiyue Lu, Eric B. Gibbs, Joshua E. Mayfield, M. Rachel Mehaffey, Yan Jessie Zhang, Jennifer S. Brodbelt, Scott A. Showalter, David S. Gilmour

“…The C-terminal domain (CTD) of RNA polymerase II is composed of a series of heptad repeats that exhibit some degree of sequence variation and that are subject to extensive phosphorylation. …”
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The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. by Yehuda Brody, Noa Neufeld, Nicole Bieberstein, Sebastien Z Causse, Eva-Maria Böhnlein, Karla M Neugebauer, Xavier Darzacq, Yaron Shav-Tal

“…Most of these processes occur co-transcriptionally while the RNA polymerase II (Pol II) enzyme is engaged in transcriptional elongation. …”
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Nucleotide Loading Modes of Human RNA Polymerase II as Deciphered by Molecular Simulations by Nicolas E. J. Génin, Robert O. J. Weinzierl

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Inhibition of RNA polymerase II allows controlled mobilisation of retrotransposons for plant breeding by Michael Thieme, Sophie Lanciano, Sandrine Balzergue, Nicolas Daccord, Marie Mirouze, Etienne Bucher

“…Even though retrotransposons fully depend on transcriptional activity of the host RNA polymerase II (Pol II) for their mobility, it was so far unclear whether Pol II is directly involved in repressing their activity. …”
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RNA polymerase II clusters form in line with surface condensation on regulatory chromatin by Agnieszka Pancholi, Tim Klingberg, Weichun Zhang, Roshan Prizak, Irina Mamontova, Amra Noa, Marcel Sobucki, Andrei Yu Kobitski, Gerd Ulrich Nienhaus, Vasily Zaburdaev, Lennart Hilbert

“…In eukaryotes, two major control points are recruitment of RNA polymerase II (Pol II) into a paused state, and subsequent pause release toward transcription. …”
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RNA Polymerase II transcription independent of TBP in murine embryonic stem cells by James ZJ Kwan, Thomas F Nguyen, Anuli C Uzozie, Marek A Budzynski, Jieying Cui, Joseph MC Lee, Filip Van Petegem, Philipp F Lange, Sheila S Teves

“…Transcription by RNA Polymerase II (Pol II) is initiated by the hierarchical assembly of the pre-initiation complex onto promoter DNA. …”
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Definition of RNA Polymerase II CoTC Terminator Elements in the Human Genome by Takayuki Nojima, Martin Dienstbier, Shona Murphy, Nicholas J. Proudfoot, Michael J. Dye

“…Mammalian RNA polymerase II (Pol II) transcription termination is an essential step in protein-coding gene expression that is mediated by pre-mRNA processing activities and DNA-encoded terminator elements. …”
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Argonaute-Bound Small RNAs from Promoter-Proximal RNA Polymerase II by Zamudio, Jesse Ray, Kelly, Timothy James, Sharp, Phillip A.

“…A subset of promoter-proximal RNA polymerase II (RNAPII) complexes produces hairpin RNAs that are processed in a DiGeorge syndrome critical region gene 8 (Dgcr8)/Drosha-independent but Dicer-dependent manner. …”
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Functional Association of Gdown1 with RNA Polymerase II Poised on Human Genes by Cheng, Bo, Li, Tiandao, Rahl, Peter B., Adamson, Todd E., Loudas, Nicholas B., Guo, Jiannan, Varzavand, Katayoun, Cooper, Jeffrey J., Hu, Xiaopeng, Gnatt, Averell, Price, David H., Young, Richard A.

“…Most human genes are loaded with promoter-proximally paused RNA polymerase II (Pol II) molecules that are poised for release into productive elongation by P-TEFb. …”
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CTD kinase associated with yeast RNA polymerase II initiation factor b. by Feaver, W, Gileadi, O, Li, Y, Kornberg, R

“…A kinase activity specific for the C-terminal repeat domain (CTD) of RNA polymerase II is associated with nearly homogeneous yeast general initiation factor b by three criteria: cofractionation on the basis of size and charge and coinactivation by mild heat treatment. …”

CHARACTERIZATION OF YEAST RNA POLYMERASE-II TRANSCRIPTION FACTOR-B AND CTD KINASE by Feaver, W, Gileadi, O, Kornberg, R

Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase II. by Dye, M, Proudfoot, N

“…The requirement of poly(A) signals to elicit transcription termination of RNA polymerase II (pol II) is firmly established. However, little else is known about the actual process of pol II transcription termination. …”

RNA polymerase II activity is located on the surface of protein-rich transcription factories. by Eskiw, C, Rapp, A, Carter, DR, Cook, P

Regulation of expression of human RNA polymerase II-transcribed snRNA genes by Guiro, J, Murphy, S

“…In addition to protein-coding genes, RNA polymerase II (pol II) transcribes numerous genes for non-coding RNAs, including the small-nuclear (sn)RNA genes. snRNAs are an important class of non-coding RNAs, several of which are involved in pre-mRNA splicing. …”

Regulation of expression of RNA polymerase II-transcribed human snRNA genes by da Rocha, J

“…Transcription initiation of snRNA genes is mediated by transcription factors like Oct-1, which recognize the DSE element, and by PTF, which recognizes the PSE and nucleates a pre-initiation complex (PIC) comprising general transcription factors TFIIA, B, C, E, F and H, TBP and some TBPassociated factors, and Mediator. RNA polymerase II (pol II) is then recruited with the carboxylterminal domain (CTD) of the large subunit in a hypophosphorylated form. …”

Interplay between influenza virus and the host RNA polymerase II transcriptional machinery by Walker, A, Fodor, E

“…Cap snatching requires an intimate association between influenza RdRP and cellular RNA polymerase II (Pol II), which is the source of nascent capped host RNAs targeted by influenza virus. …”

Role of R-loops in pause-dependent transcriptional termination of RNA polymerase II by Skourti-Stathaki, K

“…Transcription termination of RNA polymerase II (Pol II) in mammals requires a functional poly(A) signal and either downstream pause sites or co-transcriptional cleavage (CoTC) sequences together with 3’transcript degradation by the nuclear 5’-3’ exonuclease Xrn2. …”