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Transcription termination by RNA Polymerase II
Published 2012“…<p>RNA Polymerase II (Pol II) is responsible for the transcription of all protein-encoding genes. …”
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Exon tethering in transcription by RNA polymerase II.
Published 2006“…There is an emerging consensus that RNA polymerase II (RNA Pol II) transcription and pre-mRNA processing are tightly coupled events. …”
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Cracking the RNA polymerase II CTD code.
Published 2008“…The carboxyl-terminal domain (CTD) of the largest subunit of RNA polymerase II comprises multiple tandem conserved heptapeptide repeats, unique to this eukaryotic RNA polymerase. …”
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Genetic dissection of the RNA polymerase II transcription cycle
Published 2022-07-01Subjects: “…RNA polymerase II…”
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RNA polymerase II pausing in development: orchestrating transcription
Published 2022-01-01“…The coordinated regulation of transcriptional networks underpins cellular identity and developmental progression. RNA polymerase II promoter-proximal pausing (Pol II pausing) is a prevalent mechanism by which cells can control and synchronize transcription. …”
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Assembly of RNA polymerase II transcription initiation complexes
Published 2023“…The first step of eukaryotic gene expression is the assembly of RNA polymerase II and general transcription factors on promoter DNA. …”
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Influenza virus inhibits RNA polymerase II elongation.
Published 2006“…The influenza virus RNA-dependent RNA polymerase interacts with the serine-5 phosphorylated carboxy-terminal domain (CTD) of the large subunit of RNA polymerase II (Pol II). It was proposed that this interaction allows the viral RNA polymerase to gain access to host mRNA-derived capped RNA fragments required as primers for the initiation of viral mRNA synthesis. …”
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The transcription cycle of RNA polymerase II in living cells
Published 2002“…RNA polymerase II transcribes most eukaryotic genes. Its catalytic subunit was tagged with green fluorescent protein and expressed in Chinese hamster cells bearing a mutation in the same subunit; it complemented the defect and so was functional. …”
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The transcription cycle of RNA polymerase II in living cells.
Published 2002“…RNA polymerase II transcribes most eukaryotic genes. Its catalytic subunit was tagged with green fluorescent protein and expressed in Chinese hamster cells bearing a mutation in the same subunit; it complemented the defect and so was functional. …”
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Regulation of human RNA polymerase II CTD modifications
Published 2015“…<p>Transcription of human protein-coding genes and most small nuclear RNA genes is mediated by RNA Polymerase II (Pol II). During a cycle of transcription, Pol II recruits a variety of factors that facilitate transcription elongation, RNA processing and termination, through its long, unstructured C-terminal domain (CTD). …”
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Ups and Downs of Poised RNA Polymerase II in B-Cells.
Published 2016-04-01“…Recent genome-wide analyses have uncovered a high accumulation of RNA polymerase II (Pol II) at the 5' end of genes. This elevated Pol II presence at promoters, referred to here as Poll II poising, is mainly (but not exclusively) attributed to temporal pausing of transcription during early elongation which, in turn, has been proposed to be a regulatory step for processes that need to be activated "on demand". …”
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Regulation of aging by NELF-A and RNA polymerase II elongation
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Functional Consequences of Subunit Diversity in RNA Polymerases II and V
Published 2012-03-01“…Collectively, our results reveal a role for the ninth subunit in RNA silencing and demonstrate that subunit diversity generates functionally distinct subtypes of RNA polymerases II and V.…”
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Genome-wide mapping of yeast RNA polymerase II termination.
Published 2014-10-01“…Yeast RNA polymerase II (Pol II) terminates transcription of coding transcripts through the polyadenylation (pA) pathway and non-coding transcripts through the non-polyadenylation (non-pA) pathway. …”
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Repression of RNA polymerase II transcription by a Drosophila oligopeptide.
Published 2008-01-01“…This occurs through the transient repression in primordial germ cells of RNA polymerase II, specifically by disrupting Ser2 phosphorylation on its C-terminal domain. …”
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Genome-wide control of RNA polymerase II activity by cohesin.
Published 2013-03-01“…To clarify cohesin's roles in transcription, we measured how cohesin controls RNA polymerase II (Pol II) activity by genome-wide chromatin immunoprecipitation and precision global run-on sequencing. …”
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