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Alternative RNA Splicing—The Trojan Horse of Cancer Cells in Chemotherapy
Published 2021-07-01“…Almost all transcribed human genes undergo alternative RNA splicing, which increases the diversity of the coding and non-coding cellular landscape. …”
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The problem of selection bias in studies of pre-mRNA splicing
Published 2023-04-01Get full text
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23
Alternative mRNA splicing events and regulators in epidermal differentiation
Published 2024-03-01Get full text
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24
Re-evaluating the impact of alternative RNA splicing on proteomic diversity
Published 2023-02-01Get full text
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25
Epigenetic Regulation of Alternative mRNA Splicing in Dilated Cardiomyopathy
Published 2020-05-01“…In summary, this study highlights for the first time the close interrelationship between genetic imprinting by DNA methylation and the transport of this epigenetic information towards the dynamic mRNA splicing landscape. This expands our knowledge of the genome–environment interaction in DCM besides simple gene expression regulation.…”
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26
Maize PPR278 Functions in Mitochondrial RNA Splicing and Editing
Published 2022-03-01Get full text
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27
The role of alternative pre-mRNA splicing in cancer progression
Published 2023-10-01Subjects: “…Alternative pre-mRNA splicing…”
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28
Recent Insights Into the Structure, Function, and Evolution of the RNA-Splicing Endonucleases
Published 2019-02-01Subjects: “…RNA-splicing endonuclease…”
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SRSF2 is required for mRNA splicing during spermatogenesis
Published 2023-10-01“…Abstract Background RNA splicing plays significant roles in fundamental biological activities. …”
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Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing.
Published 2019-10-01Get full text
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Alternative pre-mRNA splicing in mammalian nervous system
Published 2014“…Alternative pre-mRNA splicing provides a potent post-transcriptional mechanism for diversifying the transcriptome and regulating gene expression levels. …”
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33
Combinatorial RNA splicing alters the surface charge on the NMDA receptor.
Published 1992“…Transcripts encoding four NMDA receptor subunits, generated from the NMDAR1 gene by alternative RNA splicing, have been demonstrated in adult rat brain. …”
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Engineering ER-stress dependent non-conventional mRNA splicing
Published 2018-07-01Subjects: Get full text
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Therapeutic Targeting of Alternative RNA Splicing in Gastrointestinal Malignancies and Other Cancers
Published 2021-10-01“…Our goal is to highlight key alternative RNA splicing and processing mechanisms and their roles in cancer pathophysiology as well as emerging therapeutic alternative splicing targets in cancer, particularly in gastrointestinal (GI) malignancies.…”
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Identification of potential proteins translated from circular RNA splice variants
Published 2023-03-01“…However, some multi-exonic circRNAs exist in different isoforms sharing identical backsplice junction sequences and are termed circRNA splice variants. Here, we analyzed the previously published HeLa cell RNA-seq datasets to identify circRNA splice variants using the de novo module of the CIRCexplorer2 circRNA annotation pipeline. …”
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Role of RNA Splicing Mutations in Diffuse Large B Cell Lymphoma
Published 2023-06-01Subjects: “…rna-splicing…”
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Distinct regulatory functions and biological roles of lncRNA splice variants
Published 2023-06-01“…Emerging evidence suggests significant roles for these lncRNA splice variants in many aspects of cell biology. …”
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Viral Oncogenes, Noncoding RNAs, and RNA Splicing in Human Tumor Viruses
Published 2010-01-01“…Expression of the viral E6 and E7 oncogenes in papillomavirus, E1A and E1B oncogenes in adenovirus, large T and small t antigen in polyomavirus, and Tax oncogene in HTLV-1 are regulated by alternative RNA splicing. However, this regulation is only partially understood. …”
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Analysis of Alternative mRNA Splicing in Vemurafenib-Resistant Melanoma Cells
Published 2022-07-01“…Alternative mRNA splicing is common in cancers. In BRAF V600E-mutated malignant melanoma, a frequent mechanism of acquired resistance to BRAF inhibitors involves alternative splicing (AS) of BRAF. …”
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