Showing 1 - 20 results of 2,158 for search '"RNA splicing"', query time: 0.22s Refine Results
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    Dysregulation of RNA Splicing in Tauopathies by Daniel J. Apicco, Cheng Zhang, Brandon Maziuk, Lulu Jiang, Heather I. Ballance, Samantha Boudeau, Choong Ung, Hu Li, Benjamin Wolozin

    Published 2019-12-01
    “…Summary: Pathological aggregation of RNA binding proteins (RBPs) is associated with dysregulation of RNA splicing in PS19 P301S tau transgenic mice and in Alzheimer’s disease brain tissues. …”
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    Article
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    RNA splicing: disease and therapy. by Douglas, A, Wood, M

    Published 2011
    “…The majority of human genes that encode proteins undergo alternative pre-mRNA splicing and mutations that affect splicing are more prevalent than previously thought. …”
    Journal article
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    Therapeutic Targeting of RNA Splicing in Cancer by Elizabeth A. Bonner, Stanley C. Lee

    Published 2023-06-01
    “…RNA splicing is a key regulatory step in the proper control of gene expression. …”
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    Article
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    RNA Splicing in Cancer and Targeted Therapies by Md Rafikul Islam, Preeti Nagar, Shegufta Tasneem Neetole, Ledong Wan, Mohammad Alinoor Rahman

    Published 2023-10-01
    “…Since the discovery of RNA splicing as a fundamental step to remove introns from pre-mRNA to produce mature mRNAs, substantial research in the past decades has highlighted RNA splicing as a critical mediator of gene expression and proteome diversity, also being important in many developmental and biological processes [...]…”
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    Article
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    RNA splicing is responsive to MBNL1 dose. by Sonali P Jog, Sharan Paul, Warunee Dansithong, Stephanie Tring, Lucio Comai, Sita Reddy

    Published 2012-01-01
    “…In DM1 expanded CUG repeat RNAs form hairpin secondary structures that bind and aberrantly sequester the RNA splice regulator, MBNL1. RNA splice defects resulting as a consequence of MBNL1 depletion have been shown to play a key role in the development of DM1 pathology. …”
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    Article
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    Oncogenes and RNA splicing of human tumor viruses by Masahiko Ajiro, Zhi-Ming Zheng

    Published 2014-01-01
    “…Infection with a tumor virus affects the expression of host genes, including host RNA splicing factors, which play a key role in regulating viral RNA splicing of oncogene transcripts. …”
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    Article
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    Aberrant RNA Splicing in Cancer and Drug Resistance by Bi-Dar Wang, Norman H. Lee

    Published 2018-11-01
    “…More than 95% of the 20,000 to 25,000 transcribed human genes undergo alternative RNA splicing, which increases the diversity of the proteome. …”
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    Article
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    Learning alternative RNA splicing with applications to mutagenesis by Sanders, E

    Published 2022
    “…Alternative RNA splicing is the process by which a single gene generates a large diversity of transcripts, but how the DNA sequence results in particular transcript abundances remains incompletely known. …”
    Thesis
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    Alternative mRNA Splicing and Promising Therapies in Cancer by James D. Fackenthal

    Published 2023-03-01
    Subjects: “…alternative mRNA splicing…”
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    Article
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