-
1
-
2
RNA splicing: disease and therapy.
Published 2011“…The majority of human genes that encode proteins undergo alternative pre-mRNA splicing and mutations that affect splicing are more prevalent than previously thought. …”
Journal article -
3
Therapeutic Targeting of RNA Splicing in Cancer
Published 2023-06-01“…RNA splicing is a key regulatory step in the proper control of gene expression. …”
Get full text
Article -
4
RNA Splicing in Cancer and Targeted Therapies
Published 2023-10-01“…Since the discovery of RNA splicing as a fundamental step to remove introns from pre-mRNA to produce mature mRNAs, substantial research in the past decades has highlighted RNA splicing as a critical mediator of gene expression and proteome diversity, also being important in many developmental and biological processes [...]…”
Get full text
Article -
5
-
6
Phosphorylation mediated regulation of RNA splicing in plants
Published 2023-09-01Subjects: Get full text
Article -
7
Oncogenes and RNA splicing of human tumor viruses
Published 2014-01-01“…Infection with a tumor virus affects the expression of host genes, including host RNA splicing factors, which play a key role in regulating viral RNA splicing of oncogene transcripts. …”
Get full text
Article -
8
Aberrant RNA Splicing in Cancer and Drug Resistance
Published 2018-11-01“…More than 95% of the 20,000 to 25,000 transcribed human genes undergo alternative RNA splicing, which increases the diversity of the proteome. …”
Get full text
Article -
9
Learning alternative RNA splicing with applications to mutagenesis
Published 2022“…Alternative RNA splicing is the process by which a single gene generates a large diversity of transcripts, but how the DNA sequence results in particular transcript abundances remains incompletely known. …”
Thesis -
10
-
11
Alternative mRNA Splicing and Promising Therapies in Cancer
Published 2023-03-01Subjects: “…alternative mRNA splicing…”
Get full text
Article -
12
-
13
RNA splicing alterations in lung cancer pathogenesis and therapy
Published 2023-10-01Subjects: “…RNA splicing…”
Get full text
Article -
14
Genetic regulation of RNA splicing in human pancreatic islets
Published 2022-09-01Subjects: “…RNA splicing…”
Get full text
Article -
15
Prediction of alternative pre-mRNA splicing outcomes
Published 2023-11-01“…Abstract To understand the biological impact of alternative pre-mRNA splicing, it is vital to know which exons are involved, what protein domains they encode, and how the translated isoforms differ. …”
Get full text
Article -
16
-
17
Pre-mRNA splicing-associated diseases and therapies
Published 2023-12-01“…Precursor mRNA (pre-mRNA) splicing is an essential step in human gene expression and is carried out by a large macromolecular machine called the spliceosome. …”
Get full text
Article -
18
miRNA-Based Regulation of Alternative RNA Splicing in Metazoans
Published 2021-10-01“…Alternative RNA splicing is an important regulatory process used by genes to increase their diversity. …”
Get full text
Article -
19
Changes in RNA Splicing in Developing Soybean (Glycine max) Embryos
Published 2013-11-01Get full text
Article -
20
New insights into pathogen-mediated modulation of host RNA splicing
Published 2022-08-01Subjects: “…pre-mRNA splicing…”
Get full text
Article