Systematic review: hereditary thrombophilia associated to pediatric strokes and cerebral palsy by Vinicius M. Torres, Vera A. Saddi

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Metabolomic and Physiological Changes in <i>Fagus sylvatica</i> Seedlings Infected with <i>Phytophthora plurivora</i> and the A1 and A2 Mating Types of <i>P. ×cambivora</i> by Tamara Corcobado, Ivan Milenković, Iñigo Saiz-Fernández, Tomáš Kudláček, Roman Plichta, Tomáš Májek, Aneta Bačová, Henrieta Ďatková, László Benedek Dálya, Miloš Trifković, Davide Mureddu, Vladimír Račko, Monika Kardošová, Jaroslav Ďurkovič, Roman Rattunde, Thomas Jung

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Spontaneous metastasis xenograft models link CD44 isoform 4 to angiogenesis, hypoxia, EMT and mitochondria‐related pathways in colorectal cancer by Arun Everest‐Dass, Stepan Nersisyan, Hanna Maar, Victor Novosad, Jennifer Schröder‐Schwarz, Vera Freytag, Johanna L. Stuke, Mia C. Beine, Alina Schiecke, Marie‐Therese Haider, Malte Kriegs, Omar Elakad, Hanibal Bohnenberger, Lena‐Christin Conradi, Maria Raygorodskaya, Linda Krause, Mark vonItzstein, Alexander Tonevitsky, Udo Schumacher, Diana Maltseva, Daniel Wicklein, Tobias Lange

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An In Vitro and In Vivo Assessment of Antitumor Activity of Extracts Derived from Three Well-Known Plant Species by Octavia Gligor, Simona Clichici, Remus Moldovan, Nicoleta Decea, Ana-Maria Vlase, Ionel Fizeșan, Anca Pop, Piroska Virag, Gabriela Adriana Filip, Laurian Vlase, Gianina Crișan

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An Implantable Magneto-Responsive Poly(aspartamide) Based Electrospun Scaffold for Hyperthermia Treatment by Tamás Veres, Constantinos Voniatis, Kristóf Molnár, Dániel Nesztor, Daniella Fehér, Andrea Ferencz, Iván Gresits, György Thuróczy, Bence Gábor Márkus, Ferenc Simon, Norbert Marcell Nemes, Mar García-Hernández, Lilla Reiniger, Ildikó Horváth, Domokos Máthé, Krisztián Szigeti, Etelka Tombácz, Angela Jedlovszky-Hajdu

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Cellular RNA and DNA sensing pathways are essential for the dose-dependent response of human monocytes to ionizing radiation by Natallia Mikhalkevich, Natallia Mikhalkevich, Eric Russ, Eric Russ, Eric Russ, Eric Russ, Sergey Iordanskiy, Sergey Iordanskiy

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In Vivo Imaging of Thyroid Cancer with ^99mTc-TR1401 and ^99mTc-TR1402: A Comparison Study in Dogs by Filippo Galli, Michela Varani, Chiara Lauri, Giuseppe Campagna, Lajos Balogh, Bruce D. Weintraub, Mariusz W. Szkudlinski, Armando Bartolazzi, Isabella Manni, Giulia Piaggio, Alberto Signore

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89Zr-PET imaging of DNA double-strand breaks for the early monitoring of response following α- and β-particle radioimmunotherapy in a mouse model of pancreatic ductal adenocarcinom... by Poty, S, Mandeylwala, K, O´Neill, E, Knight, JC, Cornelissen, B, Lewis, JS

“…</p> <p><strong>Conclusions:</strong> PET imaging studies with [89Zr]Zr-DFO-anti-γH2AX-TAT following α- and β-particle PRIT in a BxPC3 PDAC subcutaneous xenograft mouse model allowed the monitoring of tumor radiobiological response to treatment.</p>…”

Male-specific, replicable and functional roles of genetic variants and cerebral gray matter volumes in ADHD: a gene-wide association study across KTN1 and a region-wide functional... by Xingguang Luo, Xiandong Lin, Jaime S. Ide, Xinqun Luo, Yong Zhang, Jianying Xu, Leilei Wang, Yu Chen, Wenhong Cheng, Jianming Zheng, Zhiren Wang, Ting Yu, Reyisha Taximaimaiti, Xiaozhong Jing, Xiaoping Wang, Yuping Cao, Yunlong Tan, Chiang-Shan R. Li

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DC vaccines loaded with glioma cells killed by photodynamic therapy induce Th17 anti-tumor immunity and provide a four-gene signature for glioma prognosis by Maria Vedunova, Victoria Turubanova, Olga Vershinina, Maria Savyuk, Iuliia Efimova, Tatiana Mishchenko, Robrecht Raedt, Anne Vral, Christian Vanhove, Daria Korsakova, Claus Bachert, Frauke Coppieters, Patrizia Agostinis, Abhishek D. Garg, Mikhail Ivanchenko, Olga Krysko, Dmitri V. Krysko

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Single fraction ablative preoperative radiation treatment for early-stage breast cancer: the CRYSTAL study – a phase I/II clinical trial protocol by Maria Alessia Zerella, Mattia Zaffaroni, Giuseppe Ronci, Samantha Dicuonzo, Damaris Patricia Rojas, Anna Morra, Cristiana Fodor, Elena Rondi, Sabrina Vigorito, Francesca Botta, Marta Cremonesi, Cristina Garibaldi, Silvia Penco, Viviana Enrica Galimberti, Mattia Intra, Sara Gandini, Massimo Barberis, Giuseppe Renne, Federica Cattani, Paolo Veronesi, Roberto Orecchia, Barbara Alicja Jereczek-Fossa, Maria Cristina Leonardi

“…The study of response to RT can provide useful information about BC radiobiology, immunologic reactions, genomic expression, and radiomics features, to be tested on a larger scale. …”
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Evaluation of Global DNA Methylation and Gene Expression of <i>Izumo1</i> and <i>Izumo1r</i> in Gonads after High- and Low-Dose Radiation in Neonatal Mice by Akifumi Nakata, Keisuke Sato, Yohei Fujishima, Valerie Goh Swee Ting, Kanade Nakayama, Kentaro Ariyoshi, Chizuru Tsuruoka, Yi Shang, Daisuke Iizuka, Shizuko Kakinuma, Hideaki Yamashiro, Tomisato Miura

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Epigenetic regulation of TP53 is involved in prostate cancer radioresistance and DNA damage response signaling by Catarina Macedo-Silva, Vera Miranda-Gonçalves, Nuno Tiago Tavares, Daniela Barros-Silva, Joana Lencart, João Lobo, Ângelo Oliveira, Margareta P. Correia, Lucia Altucci, Carmen Jerónimo

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Deep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins by Sondos Samandi, Annie V Roy, Vivian Delcourt, Jean-François Lucier, Jules Gagnon, Maxime C Beaudoin, Benoît Vanderperre, Marc-André Breton, Julie Motard, Jean-François Jacques, Mylène Brunelle, Isabelle Gagnon-Arsenault, Isabelle Fournier, Aida Ouangraoua, Darel J Hunting, Alan A Cohen, Christian R Landry, Michelle S Scott, Xavier Roucou

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Catmint (Nepeta nuda L.) Phylogenetics and Metabolic Responses in Variable Growth Conditions by Detelina Petrova, Uroš Gašić, Lyubomira Yocheva, Anton Hinkov, Zhenya Yordanova, Ganka Chaneva, Desislava Mantovska, Momchil Paunov, Lyubomira Ivanova, Mariya Rogova, Kalina Shishkova, Daniel Todorov, Anita Tosheva, Veneta Kapchina-Toteva, Valya Vassileva, Atanas Atanassov, Danijela Mišić, Georgi Bonchev, Miroslava Zhiponova

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Combined Dextran-Graft-Polyacrylamide/Zinc Oxide Nanocarrier for Effective Anticancer Therapy in vitro by Chumachenko V, Virych P, Nie G, Virych P, Yeshchenko O, Khort P, Tkachenko A, Prokopiuk V, Lukianova N, Zadvornyi T, Rawiso M, Ding L, Kutsevol N

“…Kavetsky Institute for Experimental Pathology, Oncology and Radiobiology, Kyiv, Ukraine; 4Physics Department, Taras Shevchenko National University of Kyiv, Kyiv, Ukraine; 5Research Institute of Experimental and Clinical Medicine, Kharkiv National Medical University, Kharkiv, Ukraine; 6Department of Cryobiochemistry, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, Kharkiv, Ukraine; 7Institut Charles Sadron, Strasbourg, FranceCorrespondence: Guochao Nie, Guangxi Universities Key Laboratory of Complex System Optimization and Big Data Processing, Yulin Normal University, Yulin, 537000, People’s Republic of China, Tel +86-17377071871, Email bccu518@163.com Pavlo Virych, Chemistry Department, Taras Shevchenko National University of Kyiv, 60 Volodymyrska str., Kyiv, 01601, Ukraine, Tel +380-631172137, Email pavlo.virych@knu.uaIntroduction: Cancer chemotherapy faces two major challenges – high toxicity of active substances and tumor resistance to drugs. …”
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Immunogenic Cell Death, DAMPs and Prothymosin α as a Putative Anticancer Immune Response Biomarker by Anastasios I. Birmpilis, Antonios Paschalis, Apostolis Mourkakis, Panayiota Christodoulou, Ioannis V. Kostopoulos, Elina Antimissari, Georgia Terzoudi, Alexandros G. Georgakilas, Christina Armpilia, Panagiotis Papageorgis, Efstathios Kastritis, Evangelos Terpos, Meletios A. Dimopoulos, Hubert Kalbacher, Evangelia Livaniou, Maria-Ioanna Christodoulou, Ourania E. Tsitsilonis

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Combined Systemic Drug Treatment with Proton Therapy: Investigations on Patient-Derived Organoids by Max Naumann, Tabea Czempiel, Anna Jana Lößner, Kristin Pape, Elke Beyreuther, Steffen Löck, Stephan Drukewitz, Alexander Hennig, Cläre von Neubeck, Barbara Klink, Mechthild Krause, Doreen William, Daniel E. Stange, Rebecca Bütof, Antje Dietrich

“…Although we could unravel potential complications of the viability assay for PDOs in radiobiology, distinct synergistic effects of gemcitabine and 5FU with proton irradiation were observed in two PDO lines that may lead to further mechanistical studies. …”
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Supraventricular cardiac conduction system exposure in breast cancer patients treated with radiotherapy and association with heart and cardiac chambers doses by M.Y. Errahmani, M. Locquet, D. Broggio, D. Spoor, G. Jimenez, J. Camilleri, J.A. Langendijk, A.P.G. Crijns, M.O. Bernier, J. Ferrières, J. Thariat, S. Boveda, Y. Kirova, P Loap, V. Monceau, S. Jacob

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Recommendations from the COST action CA17116 (SPRINT) for the standardization of perinatal derivative preparation and in vitro testing by Aleksandar Janev, Asmita Banerjee, Asmita Banerjee, Adelheid Weidinger, Adelheid Weidinger, Jure Dimec, Brane Leskošek, Antonietta Rosa Silini, Tina Cirman, Susanne Wolbank, Susanne Wolbank, Taja Železnik Ramuta, Urška Dragin Jerman, Assunta Pandolfi, Roberta Di Pietro, Michela Pozzobon, Michela Pozzobon, Bernd Giebel, Günther Eissner, Polonca Ferk, Ingrid Lang-Olip, Francesco Alviano, Olga Soritau, Ornella Parolini, Ornella Parolini, Mateja Erdani Kreft

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