Effect of Irradiation on Reproduction of Female <i>Spodoptera litura</i> (Fabr.) (Lepidoptera: Noctuidae) in Relation to the Inherited Sterility Technique by Madhumita Sengupta, Neha Vimal, Nilza Angmo, Rakesh Kumar Seth

“…Radiobiological investigations on the reproductive behavior of female <i>Spodoptera litura</i> (Fabr.) were conducted with the aim of determining the suitable radio-sterilizing dose for females in order to release them along with sub-sterile males for effective implementation of the Inherited Sterility technique against this pest. …”
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Brachytherapy in organ-preserving treatment of choroidal melanoma: complications and the possibility of their prediction by A. A. Bykhovsky, I. E. Panova, E. V. Samkovich

“…The review highlights the historical aspects of radiation treatment, from the first experience of using ionizing radiation in the treatment of malignant neoplasms to modern methods of brachytherapy; presents the radiobiological foundations of radiation therapy; considers the issues of radiation pathomorphosis, reflecting the nature of pathological changes in the choroidal melanoma tissue during brachytherapy; shows the dependence of the effect of exposure ionizing radiation from the phase of the cycle of cell division; and also describes the presence of changes characteristic of the response to ionizing radiation in unirradiated tissues. …”
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A multicenter high-quality data registry for advanced proton therapy approaches: the POWER registry by Daniela Alterio, Maria Giulia Vincini, Stefania Volpe, Luca Bergamaschi, Mattia Zaffaroni, Sara Gandini, Giulia Peruzzotti, Federica Cattani, Cristina Garibaldi, Barbara Alicja Jereczek-Fossa, Roberto Orecchia

“…Three levels of data collection will be implemented: Level (1) clinical research (patients outcome and toxicity, quality of life, and cost/effectiveness analysis); Level (2) radiological and radiobiological research (radiomic and dosiomic analysis, as well as biological modeling); Level (3) biological and translational research (biological biomarkers and genomic data analysis). …”
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Radiotherapy treatment delays and their influence on tumour control achieved by various fractionation schedules. by Wyatt, R, Jones, B, Dale, R

“…Within the limitations of radiobiological modelling, these data can be used to tentatively assess the interactions between delays, dose fractionation and TCP. …”

Hypoxia-induced transcriptional stress is mediated by ROS-induced R-loops by Ma, TS, Worth, KR, Maher, C, Ng, N, Beghè, C, Gromak, N, Rose, AM, Hammond, EM

“…<p>Hypoxia is a common feature of solid tumors and is associated with poor patient prognosis, therapy resistance and metastasis. Radiobiological hypoxia (&lt;0.1% O₂) is one of the few physiologically relevant stresses that activates both the replication stress/DNA damage response and the unfolded protein response. …”

A possible biomedical facility at the European Organization for Nuclear Research (CERN). by Dosanjh, M, Jones, B, Myers, S

“…In addition, a modern laboratory for biomedical characterisation of these beams would allow important radiobiological studies, such as relative biological effectiveness, in a dedicated facility with standardisation of experimental conditions and biological end points. …”

Investigation of atovaquone-induced spatial changes in tumour hypoxia assessed by hypoxia PET/CT in non-small cell lung cancer patients by Bourigault, P, Skwarski, M, Macpherson, RE, Higgins, GS, McGowan, DR

“…Notably, the most intensely hypoxic tumour voxels, and therefore the most radiobiologically resistant areas, were subject to the most pronounced decrease in hypoxia in the different subregions. …”

New insights into the cellular response to radiation using microbeams by Folkard, M, Prise, K, Schettino, G, Shao, C, Gilchrist, S, Vojnovic, B

“…Micro-irradiation techniques continue to be highly relevant to a number of radiobiological studies, due to their ability to deliver precise doses of radiation to selected individual cells (or sub-cellular targets) in vitro. …”

Evaluation of a Novel Liquid Fiducial Marker, BioXmark^®, for Small Animal Image-Guided Radiotherapy Applications by Kathryn H. Brown, Mihaela Ghita, Giuseppe Schettino, Kevin M. Prise, Karl T. Butterworth

“…However, in phantom image analysis and in vivo evaluation of radiobiological response after the injection of BioXmark^® are yet to be reported. …”
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Effect of radiation dose-rate on hematopoietic cell engraftment in adult zebrafish. by Tiffany J Glass, Susanta K Hui, Bruce R Blazar, Troy C Lund

“…Overall, the adult zebrafish model of HCT indicates that exceptionally high radiation dose-rates can impact HCT outcome, and offers a new system for radiobiological and mechanistic interrogation of this phenomenon. …”
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Modeling of DNA Damage Repair and Cell Response in Relation to p53 System Exposed to Ionizing Radiation by Ankang Hu, Wanyi Zhou, Zhen Wu, Hui Zhang, Junli Li, Rui Qiu

“…The Monte Carlo track structure simulation with a more realistic repair module and the p53 system model developed in this study can expand the functions of the NASIC code in simulating mechanical radiobiological effects.…”
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Lattice or Oxygen-Guided Radiotherapy: What If They Converge? Possible Future Directions in the Era of Immunotherapy by Gianluca Ferini, Vito Valenti, Antonella Tripoli, Salvatore Ivan Illari, Laura Molino, Silvana Parisi, Alberto Cacciola, Sara Lillo, Dario Giuffrida, Stefano Pergolizzi

“…In this paper, we review the radiobiological rationale behind a potential benefit of LT-RT and OGRT, and we summarize the results reported in the few clinical trials published so far regarding these issues. …”
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A phase I dose-escalation trial of stereotactic ablative body radiotherapy for non-spine bone and lymph node metastases (DESTROY-trial) by Carole Mercier, Piet Dirix, Paul Meijnders, Peter Vermeulen, Steven Van Laere, Hilde Debois, Philippe Huget, Dirk Verellen

“…In addition, the radiobiological qualities of SABR are promising for the use in perceived radioresistant tumours. …”
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Recent Advances in Radiotherapy Modalities for Prostate Cancer by Jure Murgić, Ana Fröbe, Melvin Lee Kiang Chua

“…Over the last decade, advances in technology, imaging capabilities, and improved radiobiological understanding have deeply transformed radiotherapy for prostate cancer, allowing dose escalation and wide adoption of hypofractionation. …”
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Image Guided Radiotherapy (IGRT) and Delta (Δ) Radiomics—An Urgent Alliance for the Front Line of the War against Head and Neck Cancers by Camil Ciprian Mireștean, Roxana Irina Iancu, Dragoș Petru Teodor Iancu

“…Positron emission tomography (PET)-CT Δ radiomics could guide the new concepts of dose escalation on radio-resistant sub-volumes based on radiobiological criteria, but also guide the “next level” of HNC adaptive radiotherapy (ART).…”
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SESN2 Knockdown Increases Betulinic Acid-Induced Radiosensitivity of Hypoxic Breast Cancer Cells by Antje Güttler, Claus Weinholdt, Elisabeth Ruff, Judith Reidt, Elisa Darnstaedt, Alicia Wildemann, Marina Petrenko, Jacqueline Keßler, Matthias Kappler, Ivo Grosse, Dirk Vordermark, Matthias Bache

“…Our results identified SESN2 as an important target to enhance the radiobiological and anti-tumor effects of BA on breast cancer cells.…”
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Response of Fibroblasts from Menkes’ and Wilson’s Copper Metabolism-Related Disorders to Ionizing Radiation: Influence of the Nucleo-Shuttling of the ATM Protein Kinase by Laura El Nachef, Joëlle Al-Choboq, Michel Bourguignon, Nicolas Foray

“…Interestingly, a Cu pre-treatment of cells may influence the activity of the MRE11 nuclease and modulate the radiobiological phenotype. Lastly, some high-passage MD cells cultured in routine may transform spontaneously becoming immortalized. …”
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Radiation Effects on the On-line Monitoring System of a Hadrontherapy Center by Abdolkazem Ansarinejad, Anna Ferrari

“…Hadrontherapy is considered a promising tool for cancer treatment, given its high radiobiological effectiveness and high accuracy of dose deposition due to the physical properties of hadrons. …”
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Proton and Heavy Particle Intracranial Radiosurgery by Eric J. Lehrer, Arpan V. Prabhu, Kunal K. Sindhu, Stanislav Lazarev, Henry Ruiz-Garcia, Jennifer L. Peterson, Chris Beltran, Keith Furutani, David Schlesinger, Jason P. Sheehan, Daniel M. Trifiletti

“…While photon-based methods have been shown to be highly effective, advancements are sought for improved dose precision, treatment duration, and radiobiologic effect, among others, particularly in the setting of repeat irradiation. …”
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MC TRIM Algorithm in Mandibula Phantom in Helium Therapy by Fatih Ekinci, Koray Acici, Tunc Asuroglu, Busra Emek Soylu

“…However, they demonstrate a sharper lateral penumbra with a lower radiobiological absence of certainties and lack the degradation of variations in dose distributions caused by excessive fragmenting of heavier-ion beams, especially at greater depths of penetration. …”
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