Repeated Application of Autologous Bone Marrow-Derived Lineage-Negative Stem/Progenitor Cells—Focus on Immunological Pathways in Patients with ALS by Bartłomiej Baumert, Anna Sobuś, Monika Gołąb-Janowska, Edyta Paczkowska, Karolina Łuczkowska, Dorota Rogińska, Alicja Zawiślak, Sławomir Milczarek, Bogumiła Osękowska, Wioletta Pawlukowska, Agnieszka Meller, Karolina Machowska-Sempruch, Agnieszka Wełnicka, Krzysztof Safranow, Przemysław Nowacki, Bogusław Machaliński

“…Immune modulating procedures raise hopes for slowing the disease progression. Stem cell therapies are believed to possess the ability to regulate innate and adaptive immune response and inflammation processes. …”
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Laser-triggered combination therapy by iron sulfide-doxorubicin@functionalized nanozymes for breast cancer therapy by Shipeng Ning, Yang Zheng, Kun Qiao, Guozheng Li, Qian Bai, Shouping Xu

“…Conclusion Overall, FeS-Dox@Lf NZs with the ability to synchronize chemotherapy and gas therapy raised hopes for more effective treatment of breast cancer. …”
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Antagonistic L1 Adhesion Molecule Mimetic Compounds Inhibit Glioblastoma Cell Migration In Vitro by Vini Nagaraj, Mirai Mikhail, Micol Baronio, Alessia Gatto, Ashana Nayak, Thomas Theis, Ugo Cavallaro, Melitta Schachner

“…We now show that the L1 antagonistic mimetics anagrelide, 2-hydroxy-5-fluoropyrimidine and mestranol inhibit the migration of cultured tumor cells in an L1-dependent manner, raising hopes for therapy.…”
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CellDeathPred: a deep learning framework for ferroptosis and apoptosis prediction based on cell painting by Kenji Schorpp, Alaa Bessadok, Aidin Biibosunov, Ina Rothenaigner, Stefanie Strasser, Tingying Peng, Kamyar Hadian

“…The increasing number of studies investigating cell death types in various diseases, particularly cancer and degenerative diseases, has raised hopes for their modulation in disease therapies. …”
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Tumor-infiltrating lymphocytes for treatment of solid tumors: It takes two to tango? by Mohammad Hossein Kazemi, Mohammad Hossein Kazemi, Maryam Sadri, Maryam Sadri, Alireza Najafi, Alireza Najafi, Ali Rahimi, Ali Rahimi, Zeinab Baghernejadan, Zeinab Baghernejadan, Hossein Khorramdelazad, Reza Falak, Reza Falak

“…Gaining favorable outcomes following TIL therapy of patients with metastatic melanoma, cervical cancer, ovarian cancer, and breast cancer has raised hope in patients with refractory solid tumors, too. …”
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Timed Artificial Insemination: Pregnancy Rates in Sokoto Gudali Cattle Treated with Prostaglandin F2 Alpha at a Private Dairy Farm in Nigeria. by Olufisayo Oluwadamilare Leigh, Lukman Mustapha, Agbugba Chinyere Linda, Adaeze Ezenwanyi Ibiam

“…It is concluded therefore that timed artificial insemination at 72 h in SG cattle treated with double Estrumate® injections at 11-day interval produced the best pregnancy rate. These findings raises hope on the future application of TAI in breeding the SG cattle with  prostaglandin F2 alpha as single agent of estrus synchronization.…”
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Detection of the Release of Chlorhexidine from Cured Denture Resins Discs: Subsequently Deducing the Ability of Denture Resin as a Drug Carrier by Preethy Chandran, Sabarigirinathan Chitrapulthra Pillai, Sriramaprabu Govindasamy, Sakthidevi Arumugasamy

“…Although this study was limited in nature, the results raised hope for further evaluation of dentures as a drug delivery system.…”
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Algorithm for DNA sequence assembly by quantum annealing by Katarzyna Nałęcz-Charkiewicz, Robert M. Nowak

“…In recent years, the dynamic development of next-generation sequencing (NGS) methods raises hopes for making whole-genome sequencing a fast and reliable tool used, for example, in medical diagnostics. …”
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Nuclear and membrane expression of the angiogenesis regulator delta-like ligand 4 (DLL4) in normal and malignant human tissues. by Martinez, J, Müller, M, Turley, H, Steers, G, Choteau, L, Li, J, Sainson, R, Harris, A, Pezzella, F, Gatter, K

“…This action was believed to occur only in vascular development, raising hopes that DLL4 could be a specific drug target for controlling vessel growth in tumours and other pathological conditions. …”

Toward Islamo-Christian business ethics? A case study on the prohibitions of riba and usury and the morality of interest by Bergida, JE

“…This identification elicits comparisons with Christianity’s usury ban and raises hopes of a shared Islamo-Christian contribution to secular business ethics through a reassessment of the morality of interest.…”

Functional integrity of visual coding following advanced photoreceptor degeneration by Rodgers, J, Hughes, S, Lindner, M, Allen, A, Ebrahimi, A, Storchi, R, Peirson, S, Lucas, R, Hankins, MW

“…Photoreceptor degeneration sufficient to produce severe visual loss often spares the inner retina. This raises hope for vision restoration treatments using optogenetics or electrical stimulation, which generate a replacement light input signal in surviving neurons. …”

Exploring the Bioactive Potentials of C₆₀-AgNPs Nano-Composites against Malignancies and Microbial Infections by Kunal Biswas, Awdhesh Kumar Mishra, Pradipta Ranjan Rauta, Abdullah G. Al-Sehemi, Mehboobali Pannipara, Avik Sett, Amra Bratovcic, Satya Kumar Avula, Tapan Kumar Mohanta, Muthupandian Saravanan, Yugal Kishore Mohanta

“…Such unique electronic and physico-chemical properties of the caged carbon structure raise hope for applications into the drug delivery domain. …”
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Testing the Stability of Drug Resistance on Cryopreserved, Gene-Engineered Human Induced Pluripotent Stem Cells by Dilaware Khan, Ann-Christin Nickel, Sebastian Jeising, Constanze Uhlmann, Sajjad Muhammad, Daniel Hänggi, Igor Fischer, Ulf Dietrich Kahlert

“…Taken together, our results support iPSCs as a reliable in vitro platform for in vitro pharmacology, further raising hopes that this technology supports biomarker-associated drug development. …”
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Ethical issues raised by new genomic technologies: the case study of newborn genome screening by Rachel Horton, Anneke Lucassen

“…As genome sequencing is used more widely, diagnoses are being found for people with previously unexplained rare disease, and this has raised hopes that such analysis might usefully be employed to detect and mitigate diseases as early as possible in the life course. …”
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Advances in Ophthalmic Optogenetics: Approaches and Applications by Philipp P. Prosseda, Matthew Tran, Tia Kowal, Biao Wang, Yang Sun

“…Such approaches are attractive because they are agnostic to the genetic causes of retinal degeneration, which raises hopes that all forms of retinal dystrophic and degenerative diseases could become treatable. …”
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The potential impact of vaccination on tuberculosis burden in India: A modelling analysis by Nimalan Arinaminpathy, Kirankumar Rade, Ravinder Kumar, Rajendra P Joshi, Raghuram Rao

“…While certain vaccine candidates in advanced stages of clinical trials raise hope for the future availability of new tools, in the immediate term, there is also increasing interest in Bacille Calmette–Guérin revaccination among adults and adolescents as a potential strategy. …”
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Examining the Effect of Spiritual Health on Hope and Coping Strategies among Patients with Multiple Sclerosis (Ms) by Mahboobeh Askari, Mohadeseh Norouzi, Hamed Radmehr, Hossein Mohammadi

“…Conclusion:According to the findings, Spiritual health education can raise hope and foster effective coping strategies (problem-focused) in people who suffer from MS. …”
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Combined immunotherapy with “anti-insulin resistance” therapy as a novel therapeutic strategy against neurodegenerative diseases by Yoshiki Takamatsu, Gilbert Ho, Wakako Koike, Shuei Sugama, Takato Takenouchi, Masaaki Waragai, Jianshe Wei, Kazunari Sekiyama, Makoto Hashimoto

“…Notably, a recent study of solanezumab, an amyloid β monoclonal antibody, raises hope for the further therapeutic potential of immunotherapy, not only in Alzheimer’s disease, but also for other neurodegenerative disorders, including Parkinson’s disease. …”
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Variant surface antigen-specific IgG and protection against clinical consequences of pregnancy-associated Plasmodium falciparum malaria. by Staalsoe, T, Shulman, C, Bulmer, J, Kawuondo, K, Marsh, K, Hviid, L

“…Our data indicate an important mechanism of clinical protection against malaria and raise hope for the clinical effectiveness of a potential VSA-based vaccine against pregnancy-associated malaria.…”

Migraine and Its Association with Hyperactivity of Cell Membranes in the Course of Latent Magnesium Deficiency—Preliminary Study of the Importance of the Latent Tetany Presence in... by Joanna Cegielska, Elżbieta Szmidt-Sałkowska, Wojciech Domitrz, Małgorzata Gaweł, Maria Radziwoń-Zaleska, Izabela Domitrz

“…However, there was an apparent statistical difference between the subgroup of migraine patients with aura in relation to the control group (<i>p</i> < 0.05). The result raises hope to find a trigger for migraine attacks of this clinical form, the more that this factor may turn out to be easy to supplement with dietary supplementation.…”
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