Showing 1 - 20 results of 140 for search '"Ras (protein)"', query time: 0.11s Refine Results
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    Membrane Fusion and SNAREs: Interaction with Ras Proteins by Azzurra Margiotta

    Published 2022-07-01
    Subjects: “…Ras proteins…”
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    Article
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    The ancestral type of the R-RAS protein has oncogenic potential by Antea Talajić, Kristina Dominko, Marija Lončarić, Andreja Ambriović-Ristov, Helena Ćetković

    Published 2024-02-01
    “…Abstract Background The R-RAS2 is a small GTPase highly similar to classical RAS proteins at the regulatory and signaling levels. …”
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    Article
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    Angiotensin II profile and mRNA encoding RAS proteins during bovine follicular wave by Rogério Ferreira, Bernardo Gasperin, Joabel Santos, Monique Rovani, Robson AS Santos, Karina Gutierrez, João Francisco Oliveira, Adelina M Reis, Paulo Bayard Gonçalves

    Published 2011-12-01
    “…The objective of the present study was to characterise the AngII profile and the mRNA encoding RAS proteins in a bovine follicular wave. Cows were ovariectomised when the size between the largest (F1) and the second largest follicle (F2) was not statistically different (day 2), slightly different (day 3), or markedly different (day 4). …”
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    Article
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    Intrabodies based on intracellular capture frameworks that bind the RAS protein with high affinity and impair oncogenic transformation. by Tanaka, T, Rabbitts, T

    Published 2003
    “…We have applied in vivo intracellular antibody capture (IAC) technology to isolate human intrabodies which bind to the oncogenic RAS protein. IAC facilitates the capture of antibody fragments, in this case single-chain Fvs (scFvs), which tolerate reducing environments, such as the cytoplasm of cancer cells. …”
    Journal article
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    The Role of the Guanosine Nucleotide-Binding Protein in the Corpus Luteum by Dody Houston Billhaq, Seunghyung Lee

    Published 2021-05-01
    “…Recently, we focused on the role of RAS protein in the ovarian corpus luteum. RAS protein plays a vital role in the modulation of cell survival, proliferation, and differentiation by molecular pathway signaling. …”
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    Article
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    Mechanism of the mitogenic influence of hyperinsulinemia by Draznin Boris

    Published 2011-06-01
    “…<p>Abstract</p> <p>Either endogenous or exogenous hyperinsulinemia in the setting of insulin resistance promotes phosphorylation and activation of farnesyltransferase, a ubiquitous enzyme that farnesylates Ras protein. Increased availability of farnesylated Ras at the plasma membrane enhances mitogenic responsiveness of cells to various growth factors, thus contributing to progression of cancer and atherosclerosis. …”
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    Article
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    The metabolic landscape of RAS-driven cancers from biology to therapy by Mukhopadhyay, Suman, Vander Heiden, Matthew G, McCormick, Frank

    Published 2021
    “…Our understanding of how the RAS protein family, and in particular mutant KRAS promote metabolic dysregulation in cancer cells has advanced significantly over the last decade. …”
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    Article
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    Identification of Potential Inhibitors Targeting GTPase-Kirsten RAt Sarcoma Virus (K-Ras) Driven Cancers via E-Pharmacophore-Based Virtual Screening and Drug Repurposing Approach by Udhaya Kumar. S, Rinku Polachirakkal Varghese, V. Anu Preethi, C. George Priya Doss, Hatem Zayed

    Published 2023-11-01
    “…However, finding effective drugs that can bind to the RAS protein remains challenging. This drove us to explore new compounds that could inhibit tumor growth, particularly in cancers that harbor K-Ras mutations. …”
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    Article