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Resistance to Phytophthora infestans EC-1 clonal lineage in Solanum tuberosum by introducing the RB gene
Published 2015-04-01“…In the present work, we used Solanum bulbocastanum RB gene to confers broad spectrum resistance to P. infestans races. …”
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Functional variation in the IFNAR2 and IL10RB genes linked to persistent HBV infection.
Published 2004Conference item -
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Chile (Capsicum annuum) plants transformed with the RB gene from Solanum bulbocastanum are resistant to Phytophthora capsici.
Published 2019-01-01“…The integration of the RB gene into the genome of the primary transformants and its subsequent transfer to the F1 generation was confirmed by genomic PCR using primers specific for the RB gene. …”
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Correlation Between Transcript Abundance of the RB Gene and the Level of the RB-Mediated Late Blight Resistance in Potato
Published 2009-04-01“…Our results revealed a predictive correlation between transcript abundance of the RB gene and the level of the RB-mediated late blight resistance. …”
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A rare combination consisting of aldosterone-producing adenoma and adrenal myelolipoma in a patient with heterozygosity for retinoblastoma (RB) gene
Published 2004-03-01“…We believe that this case probably represents another variant of the multiple neoplasia syndrome and we speculate that structural alteration of the RB gene may play a role in the tumorogenesis.…”
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Analysis of the RB1 gene in patients with retinoblastoma in the Algerian population
Published 2022-04-01Subjects: Get full text
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Retinoblastoma tumor suppressor gene: An overview
Published 2012-01-01Subjects: Get full text
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Expressão do gene da leptina e seu receptor Ob-Rb no parênquima mamário de novilhas leiteiras Leptin and leptin receptor Ob-Rb gene expression in mammary parenchyma of dairy heifers
Published 2012-05-01“…<br>The objective of this study was to examine the effects of a diet with high level of energy and protein, combined with bST injections, on leptin and leptin-receptor (Ob-Rb) gene expression profile in the mammary parenchyma of dairy heifers. …”
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Detection by in situ hybridization of specific high risk HPV in archival tissue of invasive cervical carcinoma and cervical intraepithelial neoplasia using specific biotynylated HPV DNA probe in conjunction with P53 and Rb gene protein expression
Published 2002Get full text
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The status of retinoblastoma gene expression in brain tumors
Published 2022-05-01“…Given the fact that the expression of the retinoblastoma (RB) gene in malignant tumors can change the tumor behavior, we seek to investigate the alterations of RB expression in brain tumors. …”
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Loss of IL-10 signaling in macrophages limits bacterial killing driven by prostaglandin E2
Published 2020“…Induced pluripotent stem cells (iPSCs) were generated from an infantile-onset IBD patient lacking a functional IL10RB gene. Mφs differentiated from IL-10RB-/- iPSCs lacked IL-10RB mRNA expression, were unable to phosphorylate STAT3, and failed to reduce LPS induced inflammatory cytokines in the presence of exogenous IL-10. …”
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Expression of leptin and its receptor genes in the ovarian follicles of cycling and early pregnant pigs
Published 2013-01-01“…The expression of the OB-Rb gene in GC and TEC increased during pregnancy in comparison with the analyzed luteal phases of the cycle. …”
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Pressure mediated hypertrophy and mechanical stretch up-regulate expression of the long form of leptin receptor (ob-Rb) in rat cardiac myocytes
Published 2012-12-01“…</p> <p>Conclusions</p> <p>We first demonstrated that both pressure mediated hypertrophy and mechanical stretch up-regulate ob-Rb gene expression in heart and cardiac myocytes, which are thought to be important for leptin action in cardiac myocytes. …”
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Loss of heterozygosity studies at the retinoblastoma and breast cancer susceptibility (BRCA2) loci in pituitary, parathyroid, pancreatic and carcinoid tumours.
Published 1996“…OBJECTIVE: Allelic deletion of the retinoblastoma (Rb) gene on chromosome 13 has been reported in both pituitary and parathyroid tumours. …”
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Multiple QTL underlie milk phenotypes at the CSF2RB locus
Published 2019-01-01“…The extent to which two of these sites were edited also appears to be genetically co-regulated with lactation QTL, highlighting a further layer of regulatory complexity that involves the CSF2RB gene. Conclusions This locus presents a diversity of molecular and lactation QTL, likely representing multiple overlapping effects that, at a minimum, highlight the CSF2RB gene as having a causal role in these processes.…”
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An RB insensitive to CDK regulation
Published 2017-01-01“…This novel mechanism of RB regulation opens up a window for developing new cancer drug treatments for tumors harboring high CDK-Cyclin activity and a wild-type RB gene.…”
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Efficient retrovirus-mediated transfer of cell-cycle control genes to transformed cells
Published 1999-07-01“…We have chosen to study p16, p21, p53 and pRb gene transfer using the pCL-retrovirus. Described here are some general concepts and specific results of our work that indicate continued hope for the development of genetically based cancer treatments.…”
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Class II cytokine receptor gene cluster is a major locus for hepatitis B persistence.
Published 2006“…Coding changes in two of these genes, the type I IFN receptor gene, IFN-AR2, and the IL-10RB gene that encodes a receptor chain for IL-10-related cytokines including the IFN-lambdas, are associated with viral clearance (haplotype P value = 0.0003), and in vitro assays support functional roles for these variants in receptor signaling.…”
Journal article