Prehospital tranexamic acid in trauma patients: a systematic review and meta-analysis of randomized controlled trials by Pawan Acharya, Aamir Amin, Sandhya Nallamotu, Chaudhry Zaid Riaz, Venkataramana Kuruba, Virushnee Senthilkumar, Harika Kune, Sandeep Singh Bhatti, Iván Moguel Sarlat, Chekuri Vamsi Krishna, Kainat Asif, Abdulqadir J. Nashwan, Huzaifa Ahmad Cheema

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Role of prostanoids, nitric oxide and endothelin pathways in pulmonary hypertension due to COPD by Abdullah A. Alqarni, Abdullah A. Alqarni, Abdulelah M. Aldhahir, Sara A. Alghamdi, Jaber S. Alqahtani, Rayan A. Siraj, Hassan Alwafi, Abdulkareem A. AlGarni, Abdulkareem A. AlGarni, Mansour S. Majrshi, Mansour S. Majrshi, Saad M. Alshehri, Linhua Pang

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Efficacy, Safety, and Tolerability of Treatments for Systemic Sclerosis-Related Interstitial Lung Disease: A Systematic Review and Network Meta-Analysis by Gian Luca Erre, Marco Sebastiani, Maria Antonietta Fenu, Angelo Zinellu, Alberto Floris, Lorenzo Cavagna, Elisabetta Renzoni, Andreina Manfredi, Giuseppe Passiu, Richard John Woodman, Arduino Aleksander Mangoni

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Assessing the health risk of living near composting facilities on lung health, fungal and bacterial disease in cystic fibrosis: a UK CF Registry study by Muhammad Saleem Khan, Philippa Douglas, Anna L. Hansell, Nicholas J. Simmonds, Frédéric B. Piel

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Occupational exposure to particulate matter and staff sickness absence on the London underground by Justie Mak, Johanna Feary, André F.S. Amaral, Emma Marczylo, Paul Cullinan, David C. Green

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Comparison of troponin and natriuretic peptides in Takotsubo syndrome and acute coronary syndrome: a meta-analysis by Bashir Alaour, Michael Marber, Keith M Channon, Giovanni Luigi De Maria, John A Henry, Adrian P Banning, Alexander Richard Lyon, Rafail A Kotronias, Liam Steven Couch, James W Garrard, Thomas Edward Kaier

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Airway Inflammation Before and After Bronchial Thermoplasty in Severe Asthma by Wijsman PC, Goorsenberg AWM, Ravi A, d'Hooghe JNS, Dierdorp BS, Dekker T, van Schaik CCLM, ten Hacken NHT, Shah PL, Weersink EJM, Bel EH, Annema JT, Lutter R, Bonta PI

“…Pieta C Wijsman,1,* Annika WM Goorsenberg,1,* Abilash Ravi,1,2,* Julia NS d’Hooghe,1 Barbara S Dierdorp,2 Tamara Dekker,2 Charlotte CLM van Schaik,1 Nick HT ten Hacken,3 Pallav L Shah,4– 6 Els JM Weersink,1 Elisabeth H Bel,1 Jouke T Annema,1 René Lutter,1,2 Peter I Bonta1 1Department of Pulmonary Medicine, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; 2Department of Experimental Immunology, Amsterdam Infection and Immunity Institute, Amsterdam UMC, University of Amsterdam, Amsterdam, the Netherlands; 3Department of Pulmonology, University Medical Center Groningen, University of Groningen, Groningen, the Netherlands; 4Department of Pulmonology, Royal Brompton Hospital, London, UK; 5National Heart & Lung Institute, Imperial College, London, UK; 6Department of Pulmonology, Chelsea & Westminster Hospital, London, UK*These authors contributed equally to this workCorrespondence: Peter I Bonta, Email p.i.bonta@amsterdamumc.nlBackground: Bronchial thermoplasty (BT) is a bronchoscopic treatment for severe asthma, of which the working mechanism and responder profile are partly unknown. …”
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Modeled small airways lung deposition of two fixed-dose triple therapy combinations assessed with in silico functional respiratory imaging by Omar Usmani, Grace Li, Jan De Backer, Hosein Sadafi, Libo Wu, Jonathan Marshall

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Cardiac and Vascular Surgery–Associated Acute Kidney Injury: The 20th International Consensus Conference of the ADQI (Acute Disease Quality Initiative) Group by Mitra K. Nadim, Lui G. Forni, Azra Bihorac, Charles Hobson, Jay L. Koyner, Andrew Shaw, George J. Arnaoutakis, Xiaoqiang Ding, Daniel T. Engelman, Hrvoje Gasparovic, Vladimir Gasparovic, Charles A. Herzog, Kianoush Kashani, Nevin Katz, Kathleen D. Liu, Ravindra L. Mehta, Marlies Ostermann, Neesh Pannu, Peter Pickkers, Susanna Price, Zaccaria Ricci, Jeffrey B. Rich, Lokeswara R. Sajja, Fred A. Weaver, Alexander Zarbock, Claudio Ronco, John A. Kellum

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Author Correction: Epidemiological drivers of transmissibility and severity of SARS-CoV-2 in England by Pablo N. Perez-Guzman, Edward Knock, Natsuko Imai, Thomas Rawson, Yasin Elmaci, Joana Alcada, Lilith K. Whittles, Divya Thekke Kanapram, Raphael Sonabend, Katy A. M. Gaythorpe, Wes Hinsley, Richard G. FitzJohn, Erik Volz, Robert Verity, Neil M. Ferguson, Anne Cori, Marc Baguelin

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Diversity and prevalence of type VI secretion system effectors in clinical Pseudomonas aeruginosa isolates by Luca A. Robinson, Alice C. Z. Collins, Ronan A. Murphy, Jane C. Davies, Jane C. Davies, Luke P. Allsopp

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International consensus conference recommendations on ultrasound education for undergraduate medical students by Richard A. Hoppmann, Jeanette Mladenovic, Lawrence Melniker, Radu Badea, Michael Blaivas, Miguel Montorfano, Alfred Abuhamad, Vicki Noble, Arif Hussain, Gregor Prosen, Tomás Villen, Gabriele Via, Ramon Nogue, Craig Goodmurphy, Marcus Bastos, G. Stephen Nace, Giovanni Volpicelli, Richard J. Wakefield, Steve Wilson, Anjali Bhagra, Jongyeol Kim, David Bahner, Chris Fox, Ruth Riley, Peter Steinmetz, Bret P. Nelson, John Pellerito, Levon N. Nazarian, L. Britt Wilson, Irene W. Y. Ma, David Amponsah, Keith R. Barron, Renee K. Dversdal, Mike Wagner, Anthony J. Dean, David Tierney, James W. Tsung, Paula Nocera, José Pazeli, Rachel Liu, Susanna Price, Luca Neri, Barbara Piccirillo, Adi Osman, Vaughan Lee, Nitha Naqvi, Tomislav Petrovic, Paul Bornemann, Maxime Valois, Jean-Francoise Lanctot, Robert Haddad, Deepak Govil, Laura A. Hurtado, Vi Am Dinh, Robert M. DePhilip, Beatrice Hoffmann, Resa E. Lewiss, Nayana A. Parange, Akira Nishisaki, Stephanie J. Doniger, Paul Dallas, Kevin Bergman, J. Oscar Barahona, Ximena Wortsman, R. Stephen Smith, Craig A. Sisson, James Palma, Mike Mallin, Liju Ahmed, Hassan Mustafa

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Direct-acting Anticoagulants in Chronic Coronary Syndromes by Emmanuel Sorbets, Philippe Gabriel Steg

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Individualized Angiotensin‐Converting Enzyme (ACE)‐Inhibitor Therapy in Stable Coronary Artery Disease Based on Clinical and Pharmacogenetic Determinants: The PERindopril GENEtic (... by Rohit M. Oemrawsingh, K. Martijn Akkerhuis, Laura C. Van Vark, W. Ken Redekop, Goran Rudez, Willem J. Remme, Michel E. Bertrand, Kim M. Fox, Roberto Ferrari, A.H. Jan Danser, Moniek de Maat, Maarten L. Simoons, Jasper J. Brugts, Eric Boersma

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Role of vitamin D supplementation in modifying outcomes after surgery: a systematic review of randomised controlled trials by Akshay Patel, Babu Naidu, Roxanna Zakeri, David Thickett, James Hodson, Martin Hewison, Ruth Benson, Eric Lim, Paul Baker, Dimitri J Pournaras, Luke Rogers, Savannah Gysling, Edward J Caruana, Rory Morrison, Bo Khor, Jason Trevis, Tobin Mangel, Jennifer Manders, Ricky Vaja

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Primary Ciliary Dyskinesia and Retinitis Pigmentosa: Novel <i>RPGR</i> Variant and Possible Modifier Gene by Noelia Baz-Redón, Laura Sánchez-Bellver, Mónica Fernández-Cancio, Sandra Rovira-Amigo, Thomas Burgoyne, Rai Ranjit, Virginia Aquino, Noemí Toro-Barrios, Rosario Carmona, Eva Polverino, Maria Cols, Antonio Moreno-Galdó, Núria Camats-Tarruella, Gemma Marfany

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Circulating miR-133a-3p defines a low-risk subphenotype in patients with heart failure and central sleep apnea: a decision tree machine learning approach by David de Gonzalo-Calvo, Pablo Martinez-Camblor, Thalia Belmonte, Ferran Barbé, Kevin Duarte, Martin R. Cowie, Christiane E. Angermann, Andrea Korte, Isabelle Riedel, Josephine Labus, Wolfgang Koenig, Faiez Zannad, Thomas Thum, Christian Bär

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Emphysema-Predominant COPD Had a Greater 5-Year Mortality and a Worse Annual Decline in Lung Function Than Airway Obstruction-Predominant COPD or Asthma at Initial Same Degree of A... by Chang-Wei Lin, Hung-Yu Huang, Fu-Tsai Chung, Chun-Yu Lo, Yu-Chen Huang, Ting-Wen Wang, Lan-Yan Yang, Yu-Bin Pan, Kian Fan Chung, Chun-Hua Wang

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Clinical recommendations for dry powder inhaler use in the management of COPD in primary care by Marika T. Leving, Sinthia Bosnic-Anticevich, Joyce van Cooten, Jaime Correia de Sousa, Biljana Cvetkovski, Richard Dekhuijzen, Lars Dijk, Marina Garcia Pardo, Asparuh Gardev, Radosław Gawlik, Iris van der Ham, Ymke Janse, Federico Lavorini, Tiago Maricoto, Jiska Meijer, Boyd Metz, David Price, Miguel Roman-Rodriguez, Kirsten Schuttel, Nilouq Stoker, Ioanna Tsiligianni, Omar Usmani, Rachel Emerson-Stadler, Janwillem W. H. Kocks

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Fully-automated global and segmental strain analysis of DENSE cardiovascular magnetic resonance using deep learning for segmentation and phase unwrapping by Sona Ghadimi, Daniel A. Auger, Xue Feng, Changyu Sun, Craig H. Meyer, Kenneth C. Bilchick, Jie Jane Cao, Andrew D. Scott, John N. Oshinski, Daniel B. Ennis, Frederick H. Epstein

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