Dynamic epi‐transcriptomic landscape mapping with disease progression in estrogen receptor‐positive breast cancer by Stephen Keelan, Mihaela Ola, Sara Charmsaz, Sinéad Cocchiglia, Daniela Ottaviani, Seán Hickey, Siobhan Purcell, Fiona Bane, Aisling Hegarty, Ben Doherty, Katherine Sheehan, Lance Hudson, Nicola Cosgrove, Benjamin Roux, Muriel Laine, Geoffrey Greene, Damir Varešlija, Arnold Konrad Hill, Leonie Young

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Corrigendum: Mucinous adenocarcinoma of the rectum: a whole genome sequencing study by Ian S. Reynolds, Ian S. Reynolds, Valentina Thomas, Valentina Thomas, Valentina Thomas, Emer O’Connell, Emer O’Connell, Michael Fichtner, Deborah A. McNamara, Deborah A. McNamara, Elaine W. Kay, Jochen H. M. Prehn, Jochen H. M. Prehn, John P. Burke, Simon J. Furney, Simon J. Furney, Simon J. Furney

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The Fabrication and in vitro Evaluation of Retinoic Acid-Loaded Electrospun Composite Biomaterials for Tracheal Tissue Regeneration by Cian O'Leary, Cian O'Leary, Cian O'Leary, Cian O'Leary, Luis Soriano, Luis Soriano, Luis Soriano, Luis Soriano, Aidan Fagan-Murphy, Aidan Fagan-Murphy, Aidan Fagan-Murphy, Aidan Fagan-Murphy, Ivana Ivankovic, Ivana Ivankovic, Ivana Ivankovic, Ivana Ivankovic, Brenton Cavanagh, Fergal J. O'Brien, Fergal J. O'Brien, Fergal J. O'Brien, Fergal J. O'Brien, Sally-Ann Cryan, Sally-Ann Cryan, Sally-Ann Cryan, Sally-Ann Cryan, Sally-Ann Cryan

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The circadian clock influences T cell responses to vaccination by regulating dendritic cell antigen processing by Mariana P. Cervantes-Silva, Richard G. Carroll, Mieszko M. Wilk, Diana Moreira, Cloe A. Payet, James R. O’Siorain, Shannon L. Cox, Lauren E. Fagan, Paula A. Klavina, Yan He, Tabea Drewinski, Alan McGinley, Sharleen M. Buel, George A. Timmons, James O. Early, Roger J. S. Preston, Jennifer M. Hurley, David K. Finlay, Ingmar Schoen, F. Javier Sánchez-García, Kingston H. G. Mills, Annie M. Curtis

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Genetic deletion of microRNA-22 blunts the inflammatory transcriptional response to status epilepticus and exacerbates epilepsy in mice by Luiz F. Almeida Silva, Cristina R. Reschke, Ngoc T. Nguyen, Elena Langa, Amaya Sanz-Rodriguez, Rogerio R. Gerbatin, Fernanda R. Temp, Mayara L. de Freitas, Ronan M. Conroy, Gary P. Brennan, Tobias Engel, David C. Henshall

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Author Correction: Anti-angiogenic drug scheduling optimisation with application to colorectal cancer by M. Sturrock, I. S. Miller, G. Kang, N. Hannis Arba’ie, A. C. O’Farrell, A. Barat, G. Marston, P. L. Coletta, A. T. Byrne, J. H. Prehn

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Preclinical evaluation of the CDK4/6 inhibitor palbociclib in combination with a PI3K or MEK inhibitor in colorectal cancer by Cha Len Lee, Mattia Cremona, Angela Farrelly, Julie A. Workman, Sean Kennedy, Razia Aslam, Aoife Carr, Stephen Madden, Brian O’Neill, Bryan T. Hennessy, Sinead Toomey

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ADAM22/LGI1 complex as a new actionable target for breast cancer brain metastasis by Sara Charmsaz, Ben Doherty, Sinéad Cocchiglia, Damir Varešlija, Attilio Marino, Nicola Cosgrove, Ricardo Marques, Nolan Priedigkeit, Siobhan Purcell, Fiona Bane, Jarlath Bolger, Christopher Byrne, Philip J. O’Halloran, Francesca Brett, Katherine Sheehan, Kieran Brennan, Ann M. Hopkins, Stephen Keelan, Petra Jagust, Stephen Madden, Chiara Martinelli, Matteo Battaglini, Steffi Oesterreich, Adrian V. Lee, Gianni Ciofani, Arnold D. K. Hill, Leonie S. Young

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Patient’s Perception of the Role of Gym Activity in Abdominal Wall Herniation in Adults: A Prospective Study by Prabir Boruah, Rabbani Mahmoud ElSayed Hassan Daoud, Dylan Viani Walsh, Natallia Kharytaniuk, Salim Fredericks, James Ryan, Asila Abdelatif, Nuha Birido, Thomas Noel Walsh

“…This study was conducted in the Royal College of Surgeons In Ireland Department of Surgery, Connolly Hospital, Blanchardstown, Dublin, where patients with abdominal wall hernias completed a questionnaire  . …”
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Concordance between PCR-based extraction-free saliva and nasopharyngeal swabs for SARS-CoV-2 testing [version 2; peer review: 2 approved] by Chiara De Santi, Benson Jacob, Patricia Kroich, Sean Doyle, Rebecca Ward, Brian Li, Owain Donnelly, Amy Dykes, Trisha Neelakant, David Neary, Ross McGuinness, Jacqueline Cafferkey, Kieran Ryan, Veronica Quadu, Killian McGrogan, Alejandro Garcia Leon, Patrick Mallon, Fidelma Fitzpatrick, Hilary Humphreys, Eoghan De Barra, Steve W. Kerrigan, Gianpiero L. Cavalleri

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Concordance between PCR-based extraction-free saliva and nasopharyngeal swabs for SARS-CoV-2 testing [version 1; peer review: 2 approved] by Chiara De Santi, Benson Jacob, Patricia Kroich, Sean Doyle, Rebecca Ward, Brian Li, Owain Donnelly, Amy Dykes, Trisha Neelakant, David Neary, Ross McGuiness, Jacqueline Cafferkey, Kieran Ryan, Veronica Quadu, Killian McGrogan, Alejandro Garcia Leon, Patrick Mallon, Fidelma Fitzpatrick, Hilary Humphreys, Eoghan De Barra, Steve Kerrigan, Gianpiero L. Cavalleri

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von Willebrand factor links primary hemostasis to innate immunity by Clive Drakeford, Sonia Aguila, Fiona Roche, Karsten Hokamp, Judicael Fazavana, Mariana P. Cervantes, Annie M. Curtis, Heike C. Hawerkamp, Sukhraj Pal Singh Dhami, Hugo Charles-Messance, Emer E. Hackett, Alain Chion, Soracha Ward, Azaz Ahmad, Ingmar Schoen, Eamon Breen, Joe Keane, Ross Murphy, Roger J. S. Preston, Jamie M. O’Sullivan, Frederick J. Sheedy, Padraic Fallon, James S. O’Donnell

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Nanotechnology in interventional cardiology: A state-of-the-art review by Talal Almas, Rakhshan Haider, Jahanzeb Malik, Asim Mehmood, Areej Alvi, Hifza Naz, Danish Iltaf Satti, Syed Muhammad Jawad Zaidi, Abdulla K. AlSubai, Sara AlNajdi, Reema Alsufyani, Rahul Krylov Ramtohul, Abdullah Almesri, Majid Alsufyani, Abdulaziz H. Al-Bunnia, Haitham Ahmed S. Alghamdi, Yasar Sattar, M. Chadi Alraies, Sameer Raina

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Enhancing arginase 2 expression using target site blockers as a strategy to modulate macrophage phenotype by Chiara De Santi, Frances K. Nally, Remsha Afzal, Conor P. Duffy, Stephen Fitzsimons, Stephanie L. Annett, Tracy Robson, Jennifer K. Dowling, Sally-Ann Cryan, Claire E. McCoy

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Adult testicular granulosa cell tumour: A rare case report by Caroline E. Kelly, Paul C. Ryan, Nicola Cullen, Mohammed Aboelmagd, John P. Keane, Padraig J. Daly

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Identification and clinical impact of potentially actionable somatic oncogenic mutations in solid tumor samples by Sinead Toomey, Aoife Carr, Mateusz Janusz Mezynski, Yasir Elamin, Shereen Rafee, Mattia Cremona, Clare Morgan, Stephen Madden, Khairun I. Abdul-Jalil, Kathy Gately, Angela Farrelly, Elaine W. Kay, Susan Kennedy, Kenneth O’Byrne, Liam Grogan, Oscar Breathnach, Patrick G. Morris, Alexander J. Eustace, Joanna Fay, Robert Cummins, Anthony O’Grady, Roshni Kalachand, Norma O’Donovan, Fergal Kelleher, Aine O’Reilly, Mark Doherty, John Crown, Bryan T. Hennessy

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Tissue engineering and regenerative medicine strategies for the repair of tympanic membrane perforations by Elizabeth Sainsbury, Ronaldo do Amaral, Alexander W. Blayney, Rory McConn Walsh, Fergal J. O'Brien, Cian O'Leary

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Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages by Jennifer K. Dowling, Remsha Afzal, Linden J. Gearing, Mariana P. Cervantes-Silva, Stephanie Annett, Gavin M. Davis, Chiara De Santi, Nadine Assmann, Katja Dettmer, Daniel J. Gough, Glenn R. Bantug, Fidinny I. Hamid, Frances K. Nally, Conor P. Duffy, Aoife L. Gorman, Alex M. Liddicoat, Ed C. Lavelle, Christoph Hess, Peter J. Oefner, David K. Finlay, Gavin P. Davey, Tracy Robson, Annie M. Curtis, Paul J. Hertzog, Bryan R. G. Williams, Claire E. McCoy

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Steroid-free combination of 5-azacytidine and venetoclax for the treatment of multiple myeloma by Lyndsey Flanagan, Aisling Coughlan, Nicola Cosgrove, Andrew Roe, Yu Wang, Stephanie Gilmore, Izabela Drozdz, Claire Comerford, Jeremy Ryan, Emma Minihane, Salma Parvin, Michael O’Dwyer, John Quinn, Philip Murphy, Simon Furney, Siobhan Glavey, Tríona Ní Chonghaile, Leukemia Research Foundation, Science Foundation Ireland, Breakthrough Cancer Research

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Targeting the PI3K and MAPK pathways to improve response to HER2-targeted therapies in HER2-positive gastric cancer by M. Janusz Mezynski, Angela M. Farrelly, Mattia Cremona, Aoife Carr, Clare Morgan, Julie Workman, Paul Armstrong, Jennifer McAuley, Stephen Madden, Joanna Fay, Katherine M. Sheehan, Elaine W. Kay, Ciara Holohan, Yasir Elamin, Shereen Rafee, Patrick G. Morris, Oscar Breathnach, Liam Grogan, Bryan T. Hennessy, Sinead Toomey

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