Relationships between target intraocular pressure and central corneal thickness in stabilized and non-stabilized glaucoma patients by Dmitriev S. K., Peretiagin O. A., Lazar Yu.M., Tatarina Yu.A.

“…Results: Group 1 (corneal thickness, 460-489 μm; mean corneal thickness, 479 ± 7.2 μm) patients with stabilized glaucoma had the highest mean values for IOP obtained by any of the three methods at which no glaucoma progression was observed during the most recent 6 months. …”
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Six minute walking distance in kyphoscoliosis patients with chronic respiratory failure by Karakurt Zuhal, Güven Ayşem, Moçin Özlem, Karavelioğlu Yusuf, Güngör Gökay, Altınöz Hilal, Adıgüzel Nalan, Yarkın Tülay, Baran Reha

“…</p> <p>Results</p> <p>Thirty four patients with kyphoscoliosis and chronic respiratory insufficiency admitted to our outpatient clinic were included in the study but 25 (17 M) patients underwent 6MWT (8 patients walked with oxygen supplement due to PaO₂< 60 mm Hg). …”
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Self-reported neurotoxic symptoms in hip arthroplasty patients with highly elevated blood cobalt: A case-control study by Swiatkowska, I, Henckel, J, Sabah, SA, Hart, AJ

“…<br> <strong>Conclusions </strong> Frequency of reporting a number of symptoms was markedly higher in MoM patients, but clinically significant neurotoxicity was not observed (possibly due to the short exposure to elevated cobalt). …”

Comparing Relapse Rates in Real-World Patients with Schizophrenia Who Were Adequately versus Not Adequately Treated with Paliperidone Palmitate Once-Monthly Injections Before Trans... by Turkoz I, Daskiran M, Starr HL, Najarian D, Lopena O, Obando C, Keenan A, Benson C, Gopal S

“…Ibrahim Turkoz,1 Mehmet Daskiran,1 H Lynn Starr,2 Dean Najarian,2 Oliver Lopena,2 Camilo Obando,2 Alexander Keenan,3 Carmela Benson,3 Srihari Gopal4 1Statistics & Decision Sciences, Janssen Research and Development, LLC, Titusville, NJ, USA; 2Neuroscience, Janssen Scientific Affairs, LLC, Titusville, NJ, USA; 3Real World Value & Evidence, Neuroscience, Janssen Scientific Affairs, LLC, Titusville, NJ, USA; 4Schizophrenia/Neuroscience Therapeutic Area, Janssen Research and Development, LLC, Titusville, NJ, USACorrespondence: Ibrahim Turkoz, Statistics & Decision Sciences, Janssen Research & Development, 1125 Trenton-Harbourton Road, Titusville, NJ, 08560, USA, Tel +1 609-730-7719, Fax +1 609-730-3232, Email ITukoz@its.jnj.comPurpose: This retrospective cohort study evaluated real-world data on relapses in adult patients with schizophrenia who transitioned to long-acting injectable paliperidone palmitate once-every-3-months (PP3M) following treatment with once-monthly paliperidone palmitate (PP1M).Patients and Methods: Data derived from the IBM® MarketScan® Multi-State Medicaid Database were analyzed. …”
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Impact of T790M Mutation Status on Later-Line Osimertinib Treatment in Non-Small Cell Lung Cancer Patients by Yan-Jei Tang, John Wen-Cheng Chang, Ching-Fu Chang, Chen-Yang Huang, Cheng-Ta Yang, Chih-Hsi Scott Kuo, Yueh-Fu Fang, Ping-Chih Hsu, Chiao-En Wu

“…Results: A total of 172 EGFR-mutated NSCLC patients treated with frontline EGFR-TKI therapy followed by later-line osimertinib were enrolled in the current study and divided into three groups based on the T790M status (positive, negative, or unknown T790M). Patients with NSCLC harboring acquired T790M mutation treated with osimertinib had the best objective response rate (ORR) (52.6%, 25.0%, and 32.0%, <i>p</i> = 0.044), disease control rate (DCR) (79.3%, 41.7%, and 68.0%, <i>p</i> = 0.011), and progression-free survival (PFS, median PFS, 12.6, 3.1, 10.4 months, <i>p</i> = 0.001) among the three groups (positive, negative, and unknown T790M, respectively). …”
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Validating an energy expenditure prediction equation in overweight and obese Mexican patients by Gabriela Quiroz-Olguín, Aurora E. Serralde-Zúñiga, Maria Vianey Saldaña-Morales, Alfonso Gulias-Herrero, Martha Guevara-Cruz

“…Consecutive outpatients (18-70 years old) at the Clinical Nutrition were evaluated between March 2010 and August 2012 after being diagnosed with overweight or obesity (body mass index [BMI] > 25 kg/m²). Patients with any disease that could affect the measurement of gas exchange were excluded. …”
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Circulating 3‐hydroxy butyrate predicts mortality in patients with chronic heart failure with reduced ejection fraction by Kristian Hylleberg Christensen, Roni R. Nielsen, Morten Schou, Ida Gustafsson, Anders Jorsal, Allan Flyvbjerg, Lise Tarnow, Hans Erik Bøtker, Caroline Kistorp, Mogens Johannsen, Niels Møller, Henrik Wiggers

“…We observed large variations in 3‐OHB levels between patients (median 59 μM, range: 14–694 μM). Patients with 3‐OHB levels above the median displayed a markedly increased risk of death compared with those with low levels {hazard ratio [HR]: 2.1 [95% confidence interval (CI): 1.3–3.5], P = 0.003}. …”
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