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Effects of Triheptanoin on Mitochondrial Respiration and Glycolysis in Cultured Fibroblasts from Neutral Lipid Storage Disease Type M (NLSD-M) Patients
Published 2023-03-01“…In this study, we evaluated the in vitro effect of triheptanoin (Dojolvi<sup>®</sup>), a highly purified chemical triglyceride with seven carbon atoms, in fibroblasts obtained from five NLSD-M patients. Glycolytic and mitochondrial functions were determined by Seahorse XF Agylent Technology, and cellular viability and triglyceride content were measured through colorimetric assays. …”
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Patient preference and ease of use for different coagulation factor VIII reconstitution device scenarios: a cross-sectional survey in five European countries [Corrigendum]
Published 2015-02-01“…Cimino E, Linari S, Malerba M, Halimeh S, Biondo F, Westfeld M. Patient Prefer Adherence. 2014;8:1713–1720.On page 1716 Figure 2 is not accurate, this has now been corrected.Read the original article…”
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Variable Expressivity and Allelic Heterogeneity in Type 2 Familial Partial Lipodystrophy: The p.(Thr528Met) LMNA Variant
Published 2021-04-01“…Preadipocytes obtained from a T528M patient were treated with the classic adipose differentiation medium with pioglitazone. …”
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A large-scale dataset of patient summaries for retrieval-based clinical decision support systems
Published 2023-12-01“…PMC-Patients contains 167k patient summaries with 3.1 M patient-article relevance annotations and 293k patient-patient similarity annotations, which is the largest-scale resource for ReCDS and also one of the largest patient collections. …”
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The Effectiveness of Psychological Interventions for Rheumatoid Arthritis (RA): A Systematic Review and Meta-Analysis
Published 2023-03-01“…The objective of this review is to identify, appraise, and synthesize the effects of psychological interventions (e.g., cognitive behavioral therapy (CBT), emotional disclosure (ED), group therapy (GT), mindfulness (M), patient education (PE), and relaxation (R)) on biopsychosocial outcomes in the treatment of rheumatoid arthritis (RA). …”
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PERBANDINGAN EFEKTIFITAS UPAYA PREVENTIF SECARA INDIVIDUAL MENGGUNAKAN SIKAT GIGI MANUAL, SIKAT GIGI ELEKTRIK SERTA SIKAT GIGI MANUAL DENGAN DENTAL FLOSS DALAM PENCEGAHAN AKUMULASI...
Published 2013“…Plaque scores measured used plaque index PHP-M (Patient Hygiene Performance - Modified). The data is analyzed by One-Way ANOVA with 95% significant level. …”
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Association of seropositivity of toxoplasmosis and type 2 diabetes among adult females in Erbil city
Published 2023-12-01“…ELISA performed for only latex positive samples and the results were 64 ((32%) IgG+, (0%) IgM+) patient group (15.0% IgG+, 0.0% IgM+) healthy group with the P-value 0.0001 which is highly significant. …”
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Balloon Eustachian Tuboplasty Combined or Not with Myringotomy in Eustachian Tube Dysfunction
Published 2023-10-01“…No significant differences occurred in the audiometry, endoscopy, and Valsalva results or in most complications between groups. One BET + M patient had a persistent tympanic membrane perforation. …”
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Novel Linkage of Administrative Health and Family Court Data to Examine Mental Health Need Among Women Whose Children Enter Care
Published 2020-12-01“…Results 2843 (52%) women linked to a SLaM patient record via deterministic linkage. Matches had better recording of identifiers and were more likely to have returned to court than non-matches (36% vs 26%). …”
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Prognosis of Single Early-Stage Hepatocellular Carcinoma (HCC) with CEUS Inconclusive Imaging (LI-RADS LR-3 and LR-4) Is No Better than Typical HCC (LR-5)
Published 2022-01-01“…According to CEUS LI-RADS classification, 28 patients were in LR-3, 48 in LR-4, 83 in LR-5, and 8 in LR-M. Patient liver function and nodule characteristics were not statistically different between CEUS LI-RADS classes. …”
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Investigation of differentially expressed genes that contribute to therapeutic effects of bevacizumab in BRAF mutant melanoma
Published 2020“…Finally, as a predictive biomarker in AVAST-M patient samples, patients with melanomas containing high ROR2 expression trended towards a prolonged DFS after treatment with bevacizumab. …”
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Increased water intake to reduce headache: learning from a critical appraisal.
Published 2015“…Doi: 10.1093/fampra/cmr112Clinical scenarioPatients from primary care registered as ‘headache’, ‘tension headache’and/or ‘migraine’ for more than one year who suffer at least two episodes of moderately intense headache or more than four mildly intense episodes of headache per month with a daily fluid intake of less than 2.5 litres per day.PICO (M)Patient/Problem=Headache>1 year with 2 moderately intense or 4 mildly intense episodes per month Intervention=1.5 litres water per day+stress control and sleep hygiene Comparison/Control=stress control and sleep hygiene Outcome=Reduce or eliminate headache Methodology=Therapy RCTTable 1:Final Search TermsTRIP Data Base:hits = 517used filter ExtendedPrimary research 4 found1 paper applicable’Water intake ’[MeSHTerms] AND ’Headache’[All Fields]’Best match toPICO, (2012) RCTSelection Criterion and Overall Results102 headache patients in 16 primary care clinicswere randomized into control (n=50) and intervention groups (n=52) Inclusion cri-teria=two>episodes of moderately intense headache or five>mildly intense headaches per month and total fluid intake>2.5 litres per day, Follow-up @ 3 months. 79% inter-vention and 66% of controls completed RCT. …”
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Improving Medication Safety in Cancer Services for Ethnic Minority Consumers: Protocol for a Pilot Feasibility and Acceptability Study of a Co-Designed Consumer Engagement Interven...
Published 2023-09-01“…It is anticipated that by using the MiM, patient knowledge about prescribed medications and confidence in medication management will increase. …”
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Endogenous H3.3K27M derived peptide restricted to HLA-A∗02:01 is insufficient for immune-targeting in diffuse midline glioma
Published 2023-09-01“…However, we were unable to observe scFv binding, CAR T cell activation, or cytotoxic function against H3.3K27M+ patient-derived models. Despite using sensitive immunopeptidomics, we could not detect the H3.3K27M26–35-HLA-A∗02:01 peptide on these patient-derived models. …”
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Mitochondrial Impairments in Peripheral Blood Mononuclear Cells of Multiple Sclerosis Patients
Published 2022-11-01“…Mitochondrial function from M+ patients showed some impairments compared with M− patients. …”
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Risk of coronary heart disease in type 2 diabetes mellitus patients in Kelantan
Published 2011“…Kaplan Meier Product Limit Estimates, Simple and Multiple Cox regressions were performed to determine the statistically significant risk factors of developing CHO among T20M patients in Kelantan. Results: Overall survival probabilities of developing CHO in T20M patients in Kelantan was 79.2% (95% CI: 69.0%, 86.4%). …”
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Health-Related Quality of Life and Survival in Metastasized Non-Small Cell Lung Cancer Patients with and without a Targetable Driver Mutation
Published 2021-08-01“…Results: 81 metastatic NSCLC patients were included (M+ patients; 16 (20%)). M+ patients had a significantly better global HRQOL (mean difference 12.8, ES 0.61), physical functioning (mean difference 13.4, ES 0.63), and less appetite loss (mean difference 23.1, ES 0.73) at 15 weeks of follow-up compared to M− patients. …”
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The relations between joint action and theory of mind: a neuropsychological analysis.
Published 2011“…In Experiment 2, the ToM patients were asked to pay particular attention to their co-actor. …”
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The Diagnostic Value of Cerebro-spinal Fluid IgG Antibodies to Antigen 60 in Tuberculous Meningitis
Published 1998-12-01“…Anti-A60 IgG antibody was positive in 8 of 18 TbM patients. False-positive tests in controls were 3. …”
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