Population-based sequencing of Mycobacterium tuberculosis reveals how current population dynamics are shaped by past epidemics by Irving Cancino-Muñoz, Mariana G López, Manuela Torres-Puente, Luis M Villamayor, Rafael Borrás, María Borrás-Máñez, Montserrat Bosque, Juan J Camarena, Caroline Colijn, Ester Colomer-Roig, Javier Colomina, Isabel Escribano, Oscar Esparcia-Rodríguez, Francisco García-García, Ana Gil-Brusola, Concepción Gimeno, Adelina Gimeno-Gascón, Bárbara Gomila-Sard, Damiana Gónzales-Granda, Nieves Gonzalo-Jiménez, María Remedios Guna-Serrano, José Luis López-Hontangas, Coral Martín-González, Rosario Moreno-Muñoz, David Navarro, María Navarro, Nieves Orta, Elvira Pérez, Josep Prat, Juan Carlos Rodríguez, Ma Montserrat Ruiz-García, Hermelinda Vanaclocha, Valencia Region Tuberculosis Working Group, Iñaki Comas

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Pseudomonas aeruginosa antibiotic susceptibility profiles, genomic epidemiology and resistance mechanisms: a nation-wide five-year time lapse analysisResearch in context by Miquel Àngel Sastre-Femenia, Almudena Fernández-Muñoz, María Antonia Gomis-Font, Biel Taltavull, Carla López-Causapé, Jorge Arca-Suárez, Luis Martínez-Martínez, Rafael Cantón, Nieves Larrosa, Jesús Oteo-Iglesias, Laura Zamorano, Antonio Oliver, Fátima Galán-Sánchez, Irene Gracia-Ahufinger, Luis Martínez-Martínez, Carmen Liébana-Martos, Carolina Roldán, Juan Manuel Sánchez-Calvo, Encarnación Clavijo, Laura Mora-Navas, Javier Aznar, José Antonio Lepe, Ángel Rodríguez-Villodres, Esther Recacha, Francisco Javier Casas-Círia, Carmen Martínez-Rubio, Marco Antonio Sempere-Alcocer, Lina Martín-Hita, Cristina Seral, Ana Isabel López-Calleja, Carmen Aspiroz, Marisa Monforte, Pedro de la Iglesia-Martínez, Gemma Jimenez-Guerra, Elena Riera-Pérez, Carmen Collado, Carmen Gallegos, Xavier Mulet, Almudena Fernández-Muñoz, Miquel Àngel Sastre-Femenía, María Antonia Gomis-Font, Laura Zamorano, Antonio Oliver, María Siller-Ruiz, Jorge Calvo, Dolores Quesada, Jun Hao Wang, Cristina Pitart, Francesc Marco, Nuria Prim, Juan Pablo Horcajada, Eduardo Padilla, Ester Del Barrio-Tofiño, Belen Viñado-Pérez, Nieves Larrosa, Fe Tubau, Silvia Capilla, Antonio Casabella, Mar Olga Pérez-Moreno, Emma Padilla, Mónica Ballestero, Alba Rivera, Ferrán Navarro, Fréderic Gómez-Bertomeu, Sergio Pardo-Granell, Ester Picó-Plana, Dolores Guerrero, Carolina Sarvisé-Buil, Alba Belles-Belles, Marta Fernández-Esgueva, María del Pilar Ortega-Lafont, Inmaculada García, Noelia Arenal-Andrés, Susana Hernando-Real, Rosario Ibáñez, Jesús Martínez, Federico Becerra, Carmen Aldea-Mansilla, Asmaa Alaoui-Sosse, José Carlos González, Julia Guzman-Puche, Miguel Ángel Blázquez-Andrada, Nora Mariela Martínez-Ramírez, Alicia Beteta, Bárbara Gomila-Sard, Salvador Giner Almaraz, Eugenio Garduño, Pedro Miguel Juiz-González, Jorge Arca-Suárez, Javier Alba, Pilar Alonso, Ana Isabel Rodríguez, María Isabel Paz-Vidal, Marta García-Campello, Pablo Camacho, María de los Ángeles Pallarés, María Luisa Pérez del Molino, Amparo Coira, Gema Barbeito, Anniris Rincón, Francisco José Vasallo-Vidal, Laura Alonso-Acero, Laura Iglesias-Llorente, Ana Bordes-Benites, Laura Florén-Zabala, José Manuel Azcona, Carla Andrea Alonso, Yolanda Sáenz, Marta Lamata-Subero, David Molina, Ana González-Torralba, Jennifer Villa, Esther Viedma, Emilia Cercenado, Teresa Alarcón, Paula Vargas, María Díez, Rafael Cantón, Patricia Ruiz, María Isabel Sánchez-Romero, Felipe Pérez-García, Genoveva Yagüe-Guirao, Amaia Concepción Oteiza, José Leiva, María Eugenia Portillo, Andrés Canut-Blasco, Matxalen Vidal, Iker Alonso, Maider Zuriarrain, José Luis Barrios-Andrés

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Antinuclear antibodies in non-systemic autoimmune rheumatic disease dermatological conditions by Mahayidin, Hasni, Bakrin, Ikmal Hisyam

“…It is not uncommon to get positive ANA results in patients with non-SARD dermatological conditions. However, the clinical significance and usefulness of ANA has not been well established. …”

Prevalence of Anti-Dense Fine Speckled 70 Antibodies in Systemic Autoimmune Rheumatic Diseases and Healthy Controls: A Cross-sectional Study by MVNL Ram Mohan, Sukanya Sudhaharan, Liza Rajasekhar, VD Teja, Sudha Talasila

“…Anti-DFS antibodies were significantly more common in healthy individuals compared to SARD patients (p-value=0.0022). Conclusion: It is important to confirm DFS IIF pattern with a specific ELISA as isolated DFS antibodies are frequently associated with non SARD conditions.…”
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Altered Balance of Pro-Inflammatory Immune Cells to T Regulatory Cells Differentiates Symptomatic From Asymptomatic Individuals With Anti-Nuclear Antibodies by Rashi Gupta, Rashi Gupta, Emma Vanlieshout, Emma Vanlieshout, Kieran Manion, Dennisse Bonilla, Michael Kim, Carolina Muñoz-Grajales, Carolina Muñoz-Grajales, Carol Nassar, Carol Nassar, Sindhu R. Johnson, Sindhu R. Johnson, Linda T. Hiraki, Zareen Ahmad, Zareen Ahmad, Zahi Touma, Zahi Touma, Arthur Bookman, Arthur Bookman, Joan E. Wither, Joan E. Wither, Joan E. Wither, Joan E. Wither

“…Systemic Autoimmune Rheumatic Diseases (SARDs) are characterized by the production of anti-nuclear antibodies (ANAs). …”
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Multidisciplinary Evaluation of Interstitial Lung Diseases: New Opportunities Linked to Rheumatologist Involvement by Enrico De Lorenzis, Silvia Laura Bosello, Francesco Varone, Giacomo Sgalla, Lucio Calandriello, Gerlando Natalello, Bruno Iovene, Giuseppe Cicchetti, Laura Gigante, Lucrezia Verardi, Elisa Gremese, Luca Richeldi, Anna Rita Larici

“…The rheumatologist is not routinely involved in MDT, even if up to 20% of ILD are related to systemic autoimmune rheumatic diseases (SARD). The study aims to assess the agreement and its variation over time between rheumatologists and pulmonologists in the screening of SARD and between rheumatologists and an MDT extended to rheumatologists (eMDT) in evaluating the progression of SARD. …”
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Imaging Innovations in the Screening, Diagnosis, and Monitoring of Systemic Autoimmune Disease-Related Interstitial Lung Disease by Clinton Jokerst, Kavitha Yaddanapudi, Sachin Chaudhary, Ana C. Zamora, Vivek Nagaraja

“… Interstitial lung disease (ILD) is a common and serious complication of systemic autoimmune rheumatic diseases (SARD). The prevalence and prognosis of ILD vary depending on the type and severity of the underlying SARD. …”
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Evaluation of Progression From Preclinical to Systemic Autoimmune Rheumatic Disease: Novel Use of the European Alliance of Associations for Rheumatology/American College of Rheumat... by Sindhu R. Johnson, Hana Alahmari, Dennisse Bonilla, Zareen Ahmad, Arthur Bookman, Linda T. Hiraki, Earl Silverman, Zahi Touma, Mohammad Movahedi, Joan E. Wither

“…Methods We conducted a cohort study of undifferentiated and asymptomatic patients with ANAs who were assessed for the development of a SARD. The primary outcome was a diagnosis of a SARD over a two‐year period. …”
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Novel insights into systemic autoimmune rheumatic diseases using shared molecular signatures and an integrative analysis by Marie Hudson, Sasha Bernatsky, Ines Colmegna, Maximilien Lora, Tomi Pastinen, Kathleen Klein Oros, Celia M. T. Greenwood

“…We undertook this study to identify DNA methylation signatures of three systemic autoimmune rheumatic diseases (SARDs), namely rheumatoid arthritis, systemic lupus erythematosus, and systemic sclerosis, compared to healthy controls. …”
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The Deubiquitinating Enzyme AMSH1 Contributes to Plant Immunity Through Regulating the Stability of BDA1 by Yiran Wang, Weijie Huang, Xin Li, Yuelin Zhang

“…The autoimmunity of <i>snc2-1D</i> was partially affected by single mutations in <i>SARD1</i> or <i>CBP60g</i> but completely suppressed by the <i>sard1 cbp60g</i> double mutant. …”
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Rationale for phosphodiesterase-4 inhibition as a treatment strategy for interstitial lung diseases associated with rheumatic diseases by Elizabeth R Volkmann, Oliver Distler, Martin Aringer, Anna-Maria Hoffmann-Vold, Masataka Kuwana, Helmut Prosch

“…SARD-ILDs result in substantial morbidity and mortality, and there is a high medical need for effective therapies that target both fibrotic and inflammatory pathways in SARD-ILD. …”
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The Clinical Significance of the Dense Fine Speckled Immunofluorescence Pattern on HEp-2 Cells for the Diagnosis of Systemic Autoimmune Diseases by Michael Mahler, Marvin J. Fritzler

“…Even more important, the DFS IIF pattern has been reported in up to 33% of ANA positive HI, but not in ANA positive SARD sera. Since the intended use of the ANA HEp-2 test is to aid in the diagnosis and classification of SARD, the detection and reporting of anti-DFS70 antibodies and their associated pattern (DFS) as a positive test significantly reduce the specificity and the positive likelihood of the ANA test. …”
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The Role of Anti-DFS70 in the Diagnosis of Systemic Autoimmune Rheumatic Diseases by Liudmila Zotova, Victoria Kotova, Zakhar Kuznetsov

“…The diagnosis of systemic autoimmune rheumatic disease (SARD) or its exclusion is carried out taking into account the results of immunological studies, primarily antinuclear antibodies (ANA) and specific autoantibodies. …”
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Recognition and Relevance of Anti-DFS70 Autoantibodies in Routine Antinuclear Autoantibodies Testing at a Community Hospital by John B. Carter, Sara Carter, Sandra Saschenbrecker, Bruce E. Goeckeritz

“…Anti-DFS70 positive patients rarely develop systemic autoimmune rheumatic disease (SARD), especially in the absence of clinical evidence or additional anti-extractable nuclear antigen (ENA) antibodies, prompting suggestions that an isolated DFS70-specific ENA may be an exclusionary finding for SARD. …”
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Should We Adopt Increased Dilutions for Indirect Immunofluorescence in Pediatric Anti-Centromere Antibody Testing? Insights from a Three-Year Retrospective Study by Mehmet Soylu, Raziye Burcu Taşkın, Gülçin Aytaç, Güzide Aksu, Seyfi Durmaz, Miray Karakoyun, Şaziye Rüçhan Sertöz

“…Background/Objectives: Systemic autoimmune rheumatic diseases (SARDs) pose diagnostic challenges, particularly in pediatric populations, due to their diverse presentations and overlapping symptoms. …”
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Interferon and interferon-induced cytokines as markers of impending clinical progression in ANA+ individuals without a systemic autoimmune rheumatic disease diagnosis by Sonya T. Kim, Carolina Muñoz-Grajales, Shannon E. Dunn, Raphael Schneider, Sindhu R. Johnson, Zahi Touma, Zareen Ahmad, Dennisse Bonilla, Eshetu G. Atenafu, Linda T. Hiraki, Arthur Bookman, Joan Wither

“…Abstract Background Elevated levels of interferons (IFNs) are a characteristic feature of systemic autoimmune rheumatic diseases (SARDs) and may be useful in predicting impending symptomatic progression in anti-nuclear antibody-positive (ANA+) individuals lacking a SARD diagnosis. …”
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New Platform Technology for Comprehensive Serological Diagnostics of Autoimmune Diseases by Annika Willitzki, Rico Hiemann, Vanessa Peters, Ulrich Sack, Peter Schierack, Stefan Rödiger, Ursula Anderer, Karsten Conrad, Dimitrios P. Bogdanos, Dirk Reinhold, Dirk Roggenbuck

“…However, different diagnostic strategies have been proposed for the work up of sera in particular from patients with systemic autoimmune rheumatic disease (SARD). In general, screening for SARD-associated antibodies by indirect immunofluorescence (IIF) is followed by confirmatory testing covering different assay techniques. …”
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An archaeological radiocarbon database for southern Africa by Loftus, E, Mitchell, P, Ramsey, C

“…The Southern African Radiocarbon Database (SARD) is a new online, open-access database of published radiocarbon dates from southern African archaeological contexts. …”

Anti-hnRNP B1 (RA33) Autoantibodies Are Associated with the Clinical Phenotype in Russian Patients with Rheumatoid Arthritis and Systemic Sclerosis by Aleksey Maslyanskiy, Natalya Lazareva, Polina Olinek, Peter Schierack, Christian Hentschel, Juliane Cuccato, Dimitrios P. Bogdanos, Sergey V. Lapin, Dirk Roggenbuck

“…Anti-hnRNP B1 autoantibodies were significantly more prevalent in patients with SARD than controls (47/397, 11.8% versus 2/174, 1.1%; P<0.001). …”
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Penerokaan talaqqi bersanad (TB) dalam Pengajian Hadis di Malaysia by Farhah Zaidar Mohamed Ramli, Latifah Abdul Majid, Mohd Arif Nazri

“…Terdapat dua kaedah pelaksanaan TB iaitu kaedah al-sard. Sampel kes bagi kaedah al-hall wa al-bahath. …”
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