Optimum gamma irradiation doses for mutagenesis in Bambara groundnut (Vigna subterranean L.) genotypes by Maliata Athon Wanga, Ruusa Napandulwe Ithete, Rose-mary Kavemuine Hukununa, Annethe Kangumba, Magdalena Ndafapawa Hangula, Eddie B.S. Hasheela, Fatma Sarsu, Hussein Shimelis

“…Data were collected on days to emergence (DTE), emergence percentage (%EM), seedling survival percentage (%SS), seedling length (SLT), and shoot weight (STW). …”
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Construction of a mitochondrial dysfunction related signature of diagnosed model to obstructive sleep apnea by Qian Liu, Qian Liu, Tao Hao, Lei Li, Daqi Huang, Ze Lin, Ze Lin, Yipeng Fang, Dong Wang, Xin Zhang, Xin Zhang, Xin Zhang

“…Immune cell infiltration analyses were conducted using CIBERSORT and single-sample GSEA (ssGSEA).Results: we established mitochondrial dysfunction related four-gene signature of diagnostic model consisted of NPR3, PDIA3, SLPI, ERAP2, and which could easily distinguish between OSA patients and controls. …”
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Identification of a novel immune-related transcriptional regulatory network in sarcopenia by Xianzhong Zhang, Guanglou Zhu, Fengmin Zhang, Dingye Yu, Xuyang Jia, Bingwei Ma, Weizhe Chen, Xinyu Cai, Lingzhou Mao, Chengle Zhuang, Zhen Yu

“…Then, differentially expressed genes (DEGs), TFs(DETFs), pathways(DEPs), and the expression of immune gene sets were identified with limma, edgeR, GO, KEGG, ORA, GSVA, and ssGSEA. Furthermore, the results above were integrated into coexpression analysis by Pearson correlation analysis (PCA). …”
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Identification of a novel m6A-related lncRNAs signature and immunotherapeutic drug sensitivity in pancreatic adenocarcinoma by Xia-Qing Li, Shi-Qi Yin, Lin Chen, Aziguli Tulamaiti, Shu-Yu Xiao, Xue-Li Zhang, Lei Shi, Xiao-Cao Miao, Yan Yang, Xin Xing

“…The relationship between signature genes and immune function was explored by single-sample GSEA (ssGSEA). The tumor immune dysfunction and exclusion (TIDE) score and tumor mutation burden (TMB) were utilized to evaluate the response to immunotherapy. …”
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Insecticidal decay effects of long-lasting insecticide nets and indoor residual spraying on Anopheles gambiae and Anopheles arabiensis in Western Kenya by Christine L. Wanjala, Guofa Zhou, Jernard Mbugi, Jemimah Simbauni, Yaw A. Afrane, Ednah Ototo, Maxwell Gesuge, Harrysone Atieli, Andrew K. Githeko, Guiyun Yan

“…Homozygote kdr mutations of L1014S ranged from 73 to 88 % in An. gambiae s.s. dominant populations whereas L1014S mutation frequencies were relatively low (7–31 %) in An. arabiensis dominant populations. …”
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Association between Chest CT Severity Scores and SARS-CoV-2 Vaccination among COVID-19 Patients: A Cross-sectional Study from Pune, India by Ashish Laxman Atre, Akhil Atre, Suhrud Panchawagh, Rahul Khamkar, Aparna Chandorkar, Sunil Patil

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Research activity in the structure of the future doctor’s psychological readiness to the profession by E. A. Zakharova, T. M. Sorokina, E. A. Yudina

“…Rosenberg I.E., Dantas J.B., Ley T.J., Rosenberg I.E., Solomon S.S., Tom S.C. et al.) Special attention is paid to the motivational component of psychological readiness for the research activities of future doctors. …”
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Implementation of Good Clinical Practice in Early COVID-19 Pandemic by Constantin Tudor Luca, Svetlana MoS¸ teoru, Laurence Sperling, Alina Gabriela Negru, Daniela Maximov, Adina Bucur, Simina CriS¸ an, Dan Gait¸ a˘

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Renal and renal sinus fat volumes as quantified by magnetic resonance imaging in subjects with prediabetes, diabetes, and normal glucose tolerance. by Mike Notohamiprodjo, Martin Goepfert, Susanne Will, Roberto Lorbeer, Fritz Schick, Wolfgang Rathmann, Petros Martirosian, Annette Peters, Katharina Müller-Peltzer, Andreas Helck, Susanne Rospleszcz, Fabian Bamberg

“…Associations attenuated after adjustment for additional confounders were only significant for prediabetes and sinus volume (ß = 4.0 95% CI [0.4, 7.6]; p<0.05). Hypertension was significantly associated with increased sinus volume (β = 3.7, 95% CI: [0.4, 7.0; p<0.05]) and absolute sinus fat volume (β = 3.0, 95% CI: [0.7, 5.3]; p<0.05). …”
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Identification and Distribution of Novel Cressdnaviruses and Circular Molecules in Four Penguin Species in South Georgia and the Antarctic Peninsula by Hila Levy, Rafaela S. Fontenele, Ciara Harding, Crystal Suazo, Simona Kraberger, Kara Schmidlin, Anni Djurhuus, Caitlin E. Black, Tom Hart, Adrian L. Smith, Arvind Varsani

“…Using a combination of high-throughput sequencing, abutting primers-based PCR recovery of circular genomic elements, cloning, and Sanger sequencing, we detected 97 novel sequences comprising 40 ssDNA viral genomes and 57 viral-like circular molecules from 45 individual penguins. …”
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Evaluation of patient expectations for surgical treatment of degenerative disease of the lumbosacral spine by Nikita S. Zaborovskii, Anton A. Denisov, Dmitrii A. Mikhaylov, Oleg A. Smekalenkov, Sergey V. Masevnin, Vladislav S. Murakhovsky, Shamil Sh. Magomedov, Mikhail Yu. Dokish, Aleksandr P. Tatarintsev, Yuriy Yu. Polyakov, Dmitrii A. Ptashnikov

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Diversas especies de Aspergillus y amplio espectro de compromiso respiratorio by Milena Villamil Osorio, María Alejandra González, Juliana Cáceres, Sonia María Restrepo Gualteros, Germán Camacho

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Defining the Dynamic Regulation of O-GlcNAc Proteome in the Mouse Cortex---the O-GlcNAcylation of Synaptic and Trafficking Proteins Related to Neurodegenerative Diseases by Van N Huynh, Sheng Wang, Xiaosen Ouyang, Willayat Y Wani, Michelle S Johnson, Balu K Chacko, Anil G Jegga, Wei-Jun Qian, John C Chatham, Victor M Darley-Usmar, Jianhua Zhang, Jianhua Zhang

“…O-linked conjugation of ß-N-acetyl-glucosamine (O-GlcNAc) to serine and threonine residues is a post-translational modification process that senses nutrient availability and cellular stress and regulates diverse biological processes that are involved in neurodegenerative diseases and provide potential targets for therapeutics development. …”
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Monthly sulfadoxine/pyrimethamine-amodiaquine or dihydroartemisinin-piperaquine as malaria chemoprevention in young Kenyan children with sickle cell anemia: A randomized controlled... by Steve M Taylor, Sarah Korwa, Angie Wu, Cynthia L Green, Betsy Freedman, Sheila Clapp, Joseph Kipkoech Kirui, Wendy P O'Meara, Festus M Njuguna

“…<h4>Methods and findings</h4>We enrolled Kenyan children aged 1 to 10 years with homozygous hemoglobin S (HbSS) in a randomized, open-label trial conducted between January 23, 2018, and December 15, 2020, in Homa Bay, Kenya. …”
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Knowledge, Awareness and Practices of the use of Digital Technology in Dentistry among Postgraduate Students and Dental Practitioners in India: A Cross-sectional Study by Ramesh Nayakar, Poonam Sardesai, Sayed Killedar, Anandkumar Patil, Mangesh Kakodker

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The Relationship Between Resilience and Sleep Quality During the Second Wave of the COVID-19 Pandemic: A Longitudinal Study by Lenzo V, Sardella A, Musetti A, Freda MF, Lemmo D, Vegni E, Borghi L, Plazzi G, Palagini L, Castelnuovo G, Cattivelli R, Mariani R, Michelini G, Manari T, Saita E, Quattropani MC, Franceschini C

“…The Medical Outcomes Study—Sleep Scale (MOS-SS) and the Resilience Scale (RS) were administered. …”
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Comparative Evaluation of Cavosurface Marginal Integrity by Assessing Microleakage Scores of Three Different Composites using a Universal Adhesive in Self Etch and Selective Etch M... by Archie Khera, Arvind Shenoy

“…Standardised Class I cavities of 4 mm depth were prepared by a single operator with a high-speed hand piece using carbide fissure # 245 (SS White Inc) bur under air-water coolant. Samples were randomly divided into two main groups in which Single Bond Universal was used: Group I: Selective Etch Mode (30), Group II: Self Etch Mode (30). …”
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Pattern of Follow-up among Patients Attending the Department of Psychiatry: A Prospective Study by Harsimran Kaur, Pir Dutt Bansal, Arvind Sharma, Akshara Mishra, Bhavneesh Saini, Rakesh Kumar, Priyanka Bansal, Kavita Moria

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Effect of Preoperative Counselling on Intraoperative and Postoperative Satisfaction among Pregnant Women Undergoing LSCS in a Tertiary Care Centre in Manipur, India: A Quasi-Experi... by Sowrirajan Lakshminarayanan, Sinam Neetu Devi, Okram Rubina, Bishwalata Rajkumari, Rakesh Nongthombam, Kabilan Nallathambi, Divyabharathi Srinivasan, Pangeijam Radium Devi

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Exploration of Different Hypoxia Patterns and Construction of a Hypoxia-Related Gene Prognostic Index in Colorectal Cancer by Shuheng Bai, Shuheng Bai, Ling Chen, Yanli Yan, Rong Li, Yun Zhou, Xuan Wang, Haojing Kang, Zhaode Feng, Guangzu Li, Shuling Zhou, Emmanuel Kwateng Drokow, Juan Ren

“…Therefore, it is essential to conduct a comprehensive understanding of the influences of hypoxia in COAD and identify a biomarker for predicting the benefit of ICI.MethodsAn unsupervised consensus clustering algorithm was used to identify distinct hypoxia-related patterns for COAD patients from TCGA and the GEO cohorts. The ssGSEA algorithm was then used to explore the different biological processes, KEGG pathways, and immune characteristics among distinct hypoxia-related clusters. …”
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