Delphi consensus recommendation for optimization of pulmonary hypertension therapy focusing on switching from a phosphodiesterase 5 inhibitor to riociguat by Franck F. Rahaghi, Vijay P. Balasubramanian, Robert C. Bourge, Charles D. Burger, Murali M. Chakinala, Michael S. Eggert, Jean M. Elwing, Jeremy Feldman, Christopher King, James R. Klinger, Stephen C. Mathai, John Wesley McConnell, Harold I. Palevsky, Ricardo Restrepo‐Jaramillo, Zeenat Safdar, Jeffrey S. Sager, Namita Sood, Roxana Sulica, R. James White, Nicholas S. Hill

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A Multi-Omics Approach Reveals New Signatures in Obese Allergic Asthmatic Children by Mª Amelia Gomez-Llorente, Ana Martínez-Cañavate, Natalia Chueca, Mª de la Cruz Rico, Raquel Romero, Augusto Anguita-Ruiz, Concepción Mª Aguilera, Mercedes Gil-Campos, Maria D Mesa, Bekzod Khakimov, Jose Antonio Morillo, Ángel Gil, José Camacho, Carolina Gomez-Llorente

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Contribution of a Single Host Genetic Locus to Mouse Adenovirus Type 1 Infection and Encephalitis by Tien-Huei Hsu, Irene W. Althaus, Oded Foreman, Katherine R. Spindler

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Pooled microbiological findings and efficacy outcomes by pathogen in adults with community-acquired bacterial pneumonia from the Lefamulin Evaluation Against Pneumonia (LEAP) 1 and... by Susanne Paukner, Lisa Goldberg, Elizabeth Alexander, Anita F. Das, Stefanie Heinrich, Pritty Patel, Gregory J. Moran, Christian Sandrock, Thomas M. File, Jr, Jorge E. Vidal, Ken B. Waites, Steven P. Gelone, Jennifer Schranz

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Application of multidimensional structural characterization to detect and describe moderate forest disturbance by Jeff W. Atkins, Ben Bond‐Lamberty, Robert T. Fahey, Lisa T. Haber, Ellen Stuart‐Haëntjens, Brady S. Hardiman, Elizabeth LaRue, Brenden E. McNeil, David A. Orwig, Atticus E. L. Stovall, Jason M. Tallant, Jonathan A. Walter, Christopher M. Gough

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Diagnostic and molecular testing patterns in patients with newly diagnosed acute myeloid leukemia in the Connect® MDS/AML Disease Registry by Daniel A. Pollyea, Tracy I. George, Mehrdad Abedi, Rafael Bejar, Christopher R. Cogle, Kathryn Foucar, Guillermo Garcia‐Manero, David L. Grinblatt, Rami S. Komrokji, Jaroslaw P. Maciejewski, Dennis A. Revicki, Gail J. Roboz, Michael R. Savona, Bart L. Scott, Mikkael A. Sekeres, Michael A. Thompson, Sandra E. Kurtin, Chrystal U. Louis, Melissa Nifenecker, E. Dawn Flick, Arlene S. Swern, Pavel Kiselev, David P. Steensma, Harry P. Erba

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CAMx–UNIPAR simulation of secondary organic aerosol mass formed from multiphase reactions of hydrocarbons under the Central Valley urban atmospheres of California by Y. Jo, M. Jang, S. Han, A. Madhu, B. Koo, Y. Jia, Z. Yu, S. Kim, J. Park

“…The CAMx–UNIPAR model predicted SOA formation at four ground urban sites (San Jose, Sacramento, Fresno, and Bakersfield) in California, United States, during wintertime 2018. …”
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Repetitive Sampling and Control Threshold Improve 16S rRNA Gene Sequencing Results From Produced Waters Associated With Hydraulically Fractured Shale by Jenna L. Shelton, Elliott P. Barnhart, Elliott P. Barnhart, Leslie Ruppert, Aaron M. Jubb, Madalyn S. Blondes, Christina A. DeVera

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Assessing the Pregnancy Protective Impact of Scheduled Nonadherence to a Novel Progestin-Only Pill: Protocol for a Prospective, Multicenter, Randomized, Crossover Study by Edelman, Alison, Hemon, Agnes, Creinin, Mitchell, Borensztein, Pascale, Scherrer, Bruno, Glasier, Anna

“…We will recruit at 2 US sites: Oregon Health & Science University, Portland, Oregon and University of California Davis Health, Sacramento, California. Reproductive-aged subjects with regular menstrual cycles (21-35 days), BMI <32 kg/m2, and proven ovulation (screening luteal phase progesterone >3 ng/mL [>10 nmol/L]) are eligible to enroll. …”
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CRISPR-based VEGF suppression using paired guide RNAs for treatment of choroidal neovascularization by Sook Hyun Chung, Tzu-Ni Sin, Brian Dang, Taylor Ngo, Therlinder Lo, Daniella Lent-Schochet, Ratheesh K. Meleppat, Robert J. Zawadzki, Glenn Yiu

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IL-17A Increases Doxorubicin Efficacy in Triple Negative Breast Cancer by Nicholas R. Hum, Nicholas R. Hum, Aimy Sebastian, Kelly A. Martin, Naiomy D. Rios-Arce, Sean F. Gilmore, David M. Gravano, Elizabeth K. Wheeler, Matthew A. Coleman, Matthew A. Coleman, Gabriela G. Loots, Gabriela G. Loots

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Patient attitudes and preferences for the management of pregnancy of unknown location by Jessica K. Wu, B.S., Emily N. Sadecki, M.D., Moira A. Kyweluk, Ph.D., M.P.H., Suneeta Senapati, M.D., M.S.C.E., Anne N. Flynn, M.D., Elizabeth Steider, M.B.E., Tracey Thomas, M.P.H., Kurt T. Barnhart, M.D., M.S.C.E.

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T cell populations in children with autism spectrum disorder and co-morbid gastrointestinal symptoms by Destanie R. Rose, Houa Yang, Milo Careaga, Kathy Angkustsiri, Judy Van de Water, Paul Ashwood

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The influence of heart failure high-fidelity simulation education based on NLN Jeffries simulation framework in the prelicensure nursing program: A quasi-experimental study by Tricia Nwokocha, Nancy Cowan Pinio, Yan Cao, Holly Wei, Satish Mahajan

“…Methods: A heart failure high-fidelity simulation (HFHFS) education pilot project was carried out at Carrington College Sacramento. Twenty-three students participated in the study. …”
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Time- and region-dependent blood-brain barrier impairment in a rat model of organophosphate-induced status epilepticus by Pedro N. Bernardino, Brad A. Hobson, Sydney L. Huddleston, Peter M. Andrew, Jeremy A. MacMahon, Naomi H. Saito, Valerie A. Porter, Donald A. Bruun, Danielle J. Harvey, Joel R. Garbow, Angie Gelli, Abhijit J. Chaudhari, Pamela J. Lein

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Community engagement education in academic health centers, colleges, and universities by Chyke A. Doubeni, David Nelson, Elizabeth Gross Cohn, Electra Paskett, Seleshi Ayalew Asfaw, Mehek Sumar, Syed M. Ahmed, Rhonda McClinton-Brown, Mark L. Wieland, Anita Kinney, Sergio Aguilar-Gaxiola, Lisa G. Rosas, Cecilia M. Patino

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Elevated LDL-C, high blood pressure, and low peak V̇O2 associate with platelet mitochondria function in children—The Arkansas Active Kids Study by Eva C. Diaz, Eva C. Diaz, Eva C. Diaz, Sean H. Adams, Judith L. Weber, Judith L. Weber, Matthew Cotter, Elisabet Børsheim, Elisabet Børsheim, Elisabet Børsheim

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Double-Masked, Vehicle-Controlled, Randomized, Phase II Study of the Ocular Hypotensive Activity and Safety of VVN539 Ophthalmic Solution by David Wirta, MD, Xiao-Yan Li, MD, Wang Shen, PhD, Caroline Lu, MS, Gary D. Novack, PhD, William Christie, MD, Paul J. Hartman, MD, Lawrence Tafoya, MD, PhD, Navin Tekwani, MD, David Wirta, MD

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Recreating the California New Year's Flood Event of 1997 in a Regionally Refined Earth System Model by Alan M. Rhoades, Colin M. Zarzycki, Héctor A. Inda‐Diaz, Mohammed Ombadi, Ulysse Pasquier, Abhishekh Srivastava, Benjamin J. Hatchett, Eli Dennis, Anne Heggli, Rachel McCrary, Seth McGinnis, Stefan Rahimi‐Esfarjani, Emily Slinskey, Paul A. Ullrich, Michael Wehner, Andrew D. Jones

“…Extreme precipitation, snowmelt, and saturated soils produced heavy runoff causing widespread inundation in the Sacramento Valley. This study recreates the 1997 flood using the Regionally Refined Mesh capabilities of the Energy Exascale Earth System Model (RRM‐E3SM) under prescribed ocean conditions. …”
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Caracteres morfológicos de cafeeiro de porte baixo no primeiro ano de formação em Jaboticabal-SP by Matheus Grossi Terceiro, Flávia Constantino Meirelles, Adailza Guilherme Cavalcante, Fábio Luiz Checchio Mingotte, Leandro Borges Lemos

“…O diâmetro de copa foi superior nas cultivares IAC Ouro Amarelo, Catucaí 2SL, Sabiá, Catuaí Amarelo IAC 62, Sacramento MG1, Pau-Brasil MG1, Tupi IAC 125 e Tupi IAC 1669-33. …”
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