Phase 3 trial Design of the Hepatocyte Growth Factor Mimetic ANG-3777 in Renal Transplant Recipients With Delayed Graft Function by Flavio Vincenti, Jim Kim, Deborah Gouveia, Gabrielle Pelle, Tracy J. Mayne, John F. Neylan

Get full text

Clinical pilot study to evaluate the neovaginal PACIENA prosthesis® for vaginoplasty without skin grafts in women with vaginal agenesis by Pedro Acién, Francisco J. Nohales-Alfonso, Maria-Luisa Sánchez-Ferrer, Miguel Sánchez-Lozano, Victoria Navarro-Lillo, Maribel Acién

Get full text

Comprehensive Immune Monitoring of Clinical Trials to Advance Human Immunotherapy by Felix J. Hartmann, Joel Babdor, Pier Federico Gherardini, El-Ad D. Amir, Kyle Jones, Bita Sahaf, Diana M. Marquez, Peter Krutzik, Erika O’Donnell, Natalia Sigal, Holden T. Maecker, Everett Meyer, Matthew H. Spitzer, Sean C. Bendall

Get full text

Hepatocellular Carcinoma: The Role of Immunotherapy and Transplantation in the Era of Transplant Oncology by Saad Alghamdi, Waleed Al-Hamoudi

“…We deliberate on the use of ICI in the setting of the Milan criteria as well as the University of California San Francisco’s expanded criteria for liver transplantation. …”
Get full text

Inhibition of Bromodomain and Extra Terminal (BET) Domain Activity Modulates the IL-23R/IL-17 Axis and Suppresses Acute Graft-Versus-Host Disease by Katiri J. Snyder, Hannah K. Choe, Yandi Gao, Natalie E. Sell, Kara M. Braunreiter, Nina C. Zitzer, Lotus Neidemire-Colley, Sonu Kalyan, Adrienne M. Dorrance, Andrea Keller, Maria M. Mihaylova, Satishkumar Singh, Lalit Sehgal, Gideon Bollag, Yan Ma, Ben Powell, Steven M. Devine, Parvathi Ranganathan

Get full text

Descemet Endothelial Thickness Comparison Trial 1 (DETECT 1): outcome masked, placebo-controlled trial comparing two types of corneal transplant surgeries and effect of rho kinase... by Thomas M Lietman, Jennifer Rose-Nussbaumer, Bennie H Jeng, Benjamin F Arnold, Winston Chamberlain, Charles C Lin, Jennifer Y Li, William Gensheimer, Jameson Clover, Nicole Varnado, Sarah Abdelrahman

Get full text

Use of the Tissue Common Rejection Module Score in Kidney Transplant as an Objective Measure of Allograft Inflammation by Arya Zarinsefat, Jose M. Arreola Guerra, Tara Sigdel, Izabella Damm, Reuben Sarwal, Chitranon Chan-on, Gyula Szabo, Jorge L. Aguilar-Frasco, Xicohtencatl Ixtlapale-Carmona, Carlos Salinas-Ramos, Leonardo Ramirez-Martinez, Claudio Ramirez, Mario Vilatoba, Luis E. Morales Buenrostro, Josefina M. Alberu, Minnie M. Sarwal

Get full text

Efficacy and Safety of a Tofacitinib-based Immunosuppressive Regimen After Kidney Transplantation: Results From a Long-term Extension Trial by Stephan Busque, MD, MSc, FRCSC, Flavio G. Vincenti, MD, Helio Tedesco Silva, MD, Philip J. O’Connell, MD, Atsushi Yoshida, MD, John J. Friedewald, MD, Steven M. Steinberg, MD, Klemens Budde, MD, Emine N. Broeders, MD, Yon Su Kim, MD, Carolyn M. Hahn, BA, Huihua Li, MS, Gary Chan, PharmD

Get full text

Antiviral cellular therapy for enhancing T-cell reconstitution before or after hematopoietic stem cell transplantation (ACES): a two-arm, open label phase II interventional trial o... by Michael D. Keller, Patrick J. Hanley, Yueh-Yun Chi, Paibel Aguayo-Hiraldo, Christopher C. Dvorak, Michael R. Verneris, Donald B. Kohn, Sung-Yun Pai, Blachy J. Dávila Saldaña, Benjamin Hanisch, Troy C. Quigg, Roberta H. Adams, Ann Dahlberg, Shanmuganathan Chandrakasan, Hasibul Hasan, Jemily Malvar, Mariah A. Jensen-Wachspress, Christopher A. Lazarski, Gelina Sani, John M. Idso, Haili Lang, Pamela Chansky, Chase D. McCann, Jay Tanna, Allistair A. Abraham, Jennifer L. Webb, Abeer Shibli, Amy K. Keating, Prakash Satwani, Pawel Muranski, Erin Hall, Michael J. Eckrich, Evan Shereck, Holly Miller, Ewelina Mamcarz, Rajni Agarwal, Satiro N. De Oliveira, Mark T. Vander Lugt, Christen L. Ebens, Victor M. Aquino, Jeffrey J. Bednarski, Julia Chu, Suhag Parikh, Jennifer Whangbo, Michail Lionakis, Elias T. Zambidis, Elizabeth Gourdine, Catherine M. Bollard, Michael A. Pulsipher

Get full text

TRANSFORM: a novel study design to evaluate the effect of everolimus on long-term outcomes after kidney transplantation by Pascual J, Srinivas TR, Chadban S, Citterio F, Oppenheimer F, Tedesco H, Henry ML, Legendre C, Watarai Y, Sommerer C, Lee PC, Hexham JM, Dong G, Bernhardt P, Vincenti F

“…Julio Pascual,1 Titte R Srinivas,2 Steven Chadban,3 Franco Citterio,4 Federico Oppenheimer,5 Helio Tedesco,6 Mitchell L Henry,7 Christophe Legendre,8 Yoshihiko Watarai,9 Claudia Sommerer,10 Po-Chang Lee,11 J Mark Hexham,12 Gaohong Dong,12 Peter Bernhardt,13 Flavio Vincenti14 1Nephrology Department, Hospital del Mar, Barcelona, Spain; 2Division of Nephrology, Medical University of South Carolina, Mt Pleasant, SC, USA; 3Department of Transplantation, Royal Prince Alfred Hospital, Camperdown, NSW, Australia; 4Centro Trapianti d'Organo Istituto di Clinica Chirurgica, Università Cattolica del Sacro Cuore, Policlinico Universitario A Gemelli, Rome, Italy; 5Renal Transplant Unit, Hospital Clínic de Barcelona, Barcelona, Spain; 6Nephrology Division, Hospital do Rim, UNIFESP, São Paulo, Brazil; 7The Comprehensive Transplant Center, The Ohio State University, Wexner Medical Center, Columbus, OH, USA; 8Service de Transplantation Adultes, Université Paris Descartes and Hôpital Necker, Paris, France; 9Department of Transplant Surgery, Nagoya Daini Red Cross Hospital, Nagoya City, Aich, Japan; 10Medizinische Klinik, Sektion Nephrologie, Universitätsklinikum Heidelberg, Heidelberg, Germany; 11Medical College, National Cheng Kung University, Tainan City, Taiwan; 12Biometrics and Statistical Science, Novartis Pharmaceuticals, East Hanover, NJ, USA; 13Research and Development, Novartis Pharma AG, Basel, Switzerland; 14Kidney Transplant Service, University of California San Francisco, San Francisco, CA, USA Abstract: Two well defined, modifiable risk factors for kidney allograft failure are acute rejection and poor graft function at one year post-transplant. …”
Get full text

The Kidney Failure Risk Equation for Prediction of Allograft Loss in Kidney Transplant RecipientsPlain-Language Summary by Chi D. Chu, Elaine Ku, Mohammad Kazem Fallahzadeh, Charles E. McCulloch, Delphine S. Tuot

Get full text

The Option of Motion Preservation in Cervical Spondylosis: Cervical Disc Arthroplasty Update by Chih-Chang Chang, Wen-Cheng Huang, Jau-Ching Wu, Praveen V. Mummaneni

Get full text

Persistence of Virologic Response after Liver Transplant in Hepatitis C Patients Treated with Ledipasvir / Sofosbuvir Plus Ribavirin Pretransplant by Eric M. Yoshida, Paul Kwo, Kosh Agarwal, Christophe Duvoux, François Durand, Markus Peck-Radosavljevic, Leslie Lilly, Bernard Willems, Hugo Vargas, Princy Kumar, Robert S. Brown Jr., Yves Horsmans, Shampa De-Oertel, Sarah Arterburn, Hadas Dvory-Sobol, Diana M. Brainard, John G. McHutchison, Norah Terrault, Mario Rizzetto, Beat Müllhaupt

Get full text

A Review on the Management of Peripheral Neuropathic Pain Following Breast Cancer by Avila F, Torres-Guzman R, Maita K, Garcia JP, De Sario GD, Borna S, Ho OA, Forte AJ

“…Francisco Avila, Ricardo Torres-Guzman, Karla Maita, John P Garcia, Gioacchino D De Sario, Sahar Borna, Olivia A Ho, Antonio J Forte Division of Plastic Surgery, Department of Surgery, Mayo Clinic, Jacksonville, FL, USACorrespondence: Antonio J Forte, Mayo Clinic Florida, 4500 San Pablo Roads, Jacksonville, FL, 32224, USA, Tel +1 904-953-2073, Email ajvforte@yahoo.com.brAbstract: Postmastectomy pain syndrome (PMPS) is a common and debilitating form of postsurgical pain with neuropathic characteristics, presenting as burning, stabbing, or pulling sensations after mastectomy, lumpectomy, or other breast procedures. …”
Get full text