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Availability in Spain of “one-pill killers” and other highly toxic drugs in infants
Published 2020-12-01Get full text
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Peroxisomal Proliferator-Activated Receptor β/δ Deficiency Induces Cognitive Alterations
Published 2022-07-01Get full text
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Disponibilidad en España de «one pill killers» y otros medicamentos altamente tóxicos en la infancia
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Probiotic effects on immunity and microbiome in HIV-1 discordant patients
Published 2022-12-01“…The human microbiome plays a crucial role in maintaining immune homeostasis and is a potential target towards immune reconstitution.SettingRECOVER (NCT03542786) was a double-blind placebo-controlled clinical trial designed to evaluate if the novel probiotic i3.1 (AB-Biotics, Sant Cugat del Vallès, Spain) was able to improve immune reconstitution in HIV-1 infected immuno-discordant patients with stable cART and CD4+ counts <500 cells/mm3. …”
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Validación clínica de 2 agrupadores de morbilidad en el ámbito de atención primaria
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National consensus on the cardiological treatment and follow-up of Kawasaki disease
Published 2018-09-01Get full text
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Relevant Aspects of Titanium Topography for Osteoblastic Adhesion and Inhibition of Bacterial Colonization
Published 2023-05-01Get full text
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Baseline hepatitis C virus resistance-associated substitutions present at frequencies lower than 15% may be clinically significant
Published 2018-11-01“…Celia Perales,1,2,* Qian Chen,1,2,* Maria Eugenia Soria,1 Josep Gregori,1–3 Damir Garcia-Cehic,1,2 Leonardo Nieto-Aponte,4 Lluis Castells,1,2 Arkaitz Imaz,5 Meritxell Llorens-Revull,1 Esteban Domingo,2,6 Maria Buti,1,2,7 Juan Ignacio Esteban,1,2,7 Francisco Rodriguez-Frias,2,4,7 Josep Quer1,2,7 1Liver Unit, Liver Disease Laboratory-Viral Hepatitis, Internal Medicine Department, Vall d’Hebron Institut of Research (VHIR)- Vall d’Hebron University Hospital(HUVH), 08035, Barcelona, Spain; 2Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Hepáticas y Digestivas (CIBERehd) del Instituto de Salud Carlos III, 28029, Madrid, Spain; 3Roche Diagnostics SL, Sant Cugat del Vallès, 08174, Barcelona, Spain; 4Liver Pathology Unit, Department of Biochemistry and Microbiology, HUVH, 08035, Barcelona, Spain; 5HIV and STD Unit, Infectious Diseases Department, Bellvitge University Hospital-Bellvitge Biomedical Research Institut (IDIBELL), Hospitalet de Llobregat, 08907, Barcelona, Spain; 6Virology and Microbiology Department, Centro de Biología Molecular “Severo Ochoa” (CSIC-UAM), Campus de Cantoblanco, 28049, Madrid, Spain; 7Medicine Department. …”
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Whole-genome characterization and resistance-associated substitutions in a new HCV genotype 1 subtype
Published 2019-04-01“…Georg von Massow,1 Damir Garcia-Cehic,1,2 Josep Gregori,1–3 Francisco Rodriguez-Frias,2,4 María Dolores Macià,5 Ana Escarda,6 Juan Ignacio Esteban,1–2,7 Josep Quer1–2,71Liver Unit, Liver Diseases – Viral Hepatitis, Vall d’Hebron Institut of Research (VHIR) – Hospital Universitari Vall d’Hebron (HUVH), Barcelona, Spain; 2Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Instituto de Salud Carlos III, Madrid, Spain; 3Roche Diagnostics S.L., Sant Cugat del Vallès, Barcelona, Spain; 4Biochemistry and Microbiology Department, VHIR-HUVH, Barcelona, Spain; 5Unidad de Microbiología Molecular, Servicio de Microbiología, Instituto de Investigación Sanitaria de les Illes Balears (IdISBa), Hospital Universitario Son Espases, Mallorca, Spain; 6Digestive Department, Hospital Universitario Son Espases, Mallorca, Spain; 7Medicine Department, Universitat Autònoma de Barcelona, Barcelona, SpainAbstract: Hepatitis C virus (HCV) is a highly variable infectious agent, classified into 8 genotypes and 86 subtypes. …”
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Cost-effectiveness of tiotropium versus glycopyrronium in moderate to very severe chronic obstructive pulmonary disease in Canada, Spain, Sweden, and the UK
Published 2016-06-01“…Oskar Eklund,1 Faraz Afzal,2 Fredrik Borgström,1 Jason Flavin,3 Andrew Ternouth,4 Maria Eugenia Ojanguren,5 Carlos Crespo,5 Mike Baldwin6 1Quantify Research AB, Stockholm, Sweden; 2Boehringer Ingelheim, Asker, Norway; 3Boehringer Ingelheim, Burlington, ON, Canada; 4Boehringer Ingelheim, Bracknell, Berkshire, UK; 5Boehringer Ingelheim, Sant Cugat del Vallès, Barcelona, Spain; 6Boehringer Ingelheim, Ingelheim, Germany Objectives: Tiotropium (TIO), Spiriva® Handihaler®, is a well-established bronchodilator, LAMA (long acting muscarinic antagonist), for the treatment of moderate to very severe chronic obstructive pulmonary disease (COPD). …”
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Artificial Intelligence to Identify Retinal Fundus Images, Quality Validation, Laterality Evaluation, Macular Degeneration, and Suspected Glaucoma
Published 2020-02-01“…Miguel Angel Zapata,1 Dídac Royo-Fibla,1 Octavi Font,1 José Ignacio Vela,2,3 Ivanna Marcantonio,2,3 Eduardo Ulises Moya-Sánchez,4,5 Abraham Sánchez-Pérez,5 Darío Garcia-Gasulla,4 Ulises Cortés,4,6 Eduard Ayguadé,4,6 Jesus Labarta4,6 1Optretina, Barcelona, Spain; 2Ophthalmology Department, Hospital de la Santa Creu I de Sant Pau, Barcelona 08041, Spain; 3Universitat Autònoma de Barcelona (UAB), Campus de la UAB, Barcelona, Spain; 4Barcelona Supercomputing Center (BSC), Barcelona, Spain; 5Universidad Autónoma de Guadalajara - Postgrado en Ciencias Computacionales, Guadalajara, Mexico; 6Universitat Politècnica de Catalunya - BarcelonaTECH, Campus Nord, Barcelona, SpainCorrespondence: Miguel Angel ZapataOptretina, C/ Las Palmas 11, 08195 Sant Cugat del Vallès, Barcelona, SpainTel +34 655809682Email mazapata@optretina.comPurpose: To assess the performance of deep learning algorithms for different tasks in retinal fundus images: (1) detection of retinal fundus images versus optical coherence tomography (OCT) or other images, (2) evaluation of good quality retinal fundus images, (3) distinction between right eye (OD) and left eye (OS) retinal fundus images,(4) detection of age-related macular degeneration (AMD) and (5) detection of referable glaucomatous optic neuropathy (GON).Patients and Methods: Five algorithms were designed. …”
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Deep-sequencing study of HCV G4a resistance-associated substitutions in Egyptian patients failing DAA treatment
Published 2019-09-01“…Fatma Amer,1 Monkez M Yousif,2 Noha M Hammad,1 Damir Garcia-Cehic,3,4 Josep Gregori,3–5 Ariadna Rando-Segura,6 Leonardo Nieto-Aponte,6 Juan Ignacio Esteban,3,4 Francisco Rodriguez-Frias,4,6 Josep Quer3,4 1Department of Medical Microbiology and Immunology, Faculty of Medicine, Medical College, Zagazig University, Zagazig, Egypt; 2Internal Medicine Department , Faculty of Medicine, Medical College, Zagazig University, Zagazig, Egypt; 3Liver Unit, Liver Disease Laboratory-Viral Hepatitis, Internal Medicine Department, Vall d’Hebron Institut Recerca (VHIR)-Hospital Universitari Vall d’Hebron (HUVH), Barcelona 08035, Spain; 4Centro de Investigación Biomédica en Red (CIBER) de Enfermedades Hepáticas y Digestivas (CIBERehd) del Instituto de Salud Carlos III, Madrid 28029, Spain; 5Business Development Department, Roche Diagnostics SL, Sant Cugat del Vallès, Barcelona 08174, Spain; 6Liver Pathology Unit, Department of Biochemistry and Microbiology, HUVH, Barcelona 08035, SpainCorrespondence: Josep QuerLiver Unit, Liver Disease Laboratory-Viral Hepatitis, Internal Medicine Department, Vall d’Hebron Institut Recerca (VHIR-HUVH), Barcelona 08035, SpainTel +34 93 489 4034Email josep.quer@vhir.orgFatma AmerMedical Microbiology and Immunology Department, Zagazig Faculty of Medicine, 9A, Road 275, New Maadi, Cairo, Zagazig, EgyptTel +20 122 313 4810Email egyamer@yahoo.comPurpose: To study resistance-associated substitutions using next-generation sequencing in Egyptian hepatitis C virus-infected patients failing direct-acting antiviral treatment.Methods: The current study describes three cases of treatment failure in patients referred to Zagazig Viral Hepatitis Treatment Center (ZVHTC), Sharkia Governorate, Egypt. …”
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A Co-Design Process to Elaborate Educational Materials to Promote Appropriate Use of Antibiotics for Acute Lower Respiratory Tract Infections in Primary Healthcare in Catalonia (Sp...
Published 2021-03-01“…Laura Medina-Perucha,1 Pablo Gálvez-Hernández,2,3 Ana García-Sangenís,1,4 Ana Moragas,5 Josep María Cots,6 Anna Lanau-Roig,6 Alícia Borrás,2,7 Isabel Amo,2 Nieves Barragán,8 Ramon Monfá,1,4 Carl Llor,1,9 Anna Berenguera1,4,10 1Fundació Institut Universitari per a la recerca a l’Atenció Primària de Salut Jordi Gol i Gurina (IDIAPJGol), Barcelona, Spain; 2Institut Universitari de Pacients (Patients’ University Institut), Universitat Internacional de Catalunya, Barcelona, Spain; 3University of Toronto, IHPME-BFON Collaborative PhD Specialization Program in Health Services and Policy Research, Ontario, Canada; 4Universitat Autònoma de Barcelona, Bellaterra (Cerdanyola del Vallès), Spain; 5Universitat Rovira i Virgili, Jaume I Health Centre, Institut Català de la Salut, Tarragona, Spain; 6La Marina Health Centre, Institut Català de la Salut, Associació d’Infermeria Familiar i Comunitària de Catalunya, Barcelona, Spain; 7Escola Universitària d’Infermeria, Escoles Universitàries Gimbernat, Universitat Autònoma de Barcelona, Sant Cugat del Vallès, Spain; 8Societat Catalana de Medicina Familiar i Comunitària (Camfic), Grupo Programa Comunicación y Salud semFYC. …”
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