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Auxiliary role of D5 dopamine receptor as a marker in paranoid schizophrenia patients
Published 2019-04-01“…Newly progress in molecular biology and imaging techniques has enabled new insight into schizophrenia research. Recent research reveals the key roles of D3, D4 and D5 dopamine receptor in presenting types of schizophrenia, particularly the paranoid. …”
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402
Psychological Study of Schizophrenia by S. N. Spielrein in the Light of Disciplinary Crisis of Psychiatry in the Beginning of the XX Century
Published 2016-03-01“…The article considers the formation of innovative psychological method of schizophrenia research performed by S. Spielrein in her dissertation “On the psychological content of a single case of schizophrenia” (1911). …”
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403
Birth weight, family history of diabetes and diabetes onset in schizophrenia
Published 2020-04-01“…IntroductionThe prevalence of diabetes in schizophrenia is twice that in the general population, but there are few reliable predictors of which individuals will develop glucose dysregulation.ObjectiveTo test if abnormal birth weight (either too low or too high) and parental diabetes, both variables that can be ascertained in the clinic, can predict diabetes onset in patients with schizophrenia.Research design and methodsElectronic records of a cohort of 190 clozapine-treated patients (37% treated for more than 20 years) and Cox regression survival analysis (with any type of glucose dysregulation as the event) to account for differences in length of treatment before the event and age at clozapine treatment initiation.ResultsAge at clozapine initiation (Exp(B)=1.098; p<0.001), family history of diabetes (Exp(B)=2.299; p=0.049) and birth weight2 (Exp(B)=0.999; p=0.013) were significant predictors of glucose dysregulation onset, while gender was not (Exp(B)=0.1.350; p=0.517). …”
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404
Implications of Information Theory for Computational Modeling of Schizophrenia
Published 2017-10-01Get full text
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Does abnormal sleep impair memory consolidation in schizophrenia?
Published 2009-09-01“…Amelioration of cognitive deficits is a current priority of the schizophrenia research community, but most efforts to define, characterize, and quantify cognitive deficits focus on cross-sectional measures. …”
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409
Schizophrenia-like behavior is not altered by melatonin supplementation in rodents
Published 2020-08-01“…Abstract An emerging area in schizophrenia research focuses on the impact of immunomodulatory drugs such as melatonin, which have played important roles in many biological systems and functions, and appears to be promising. …”
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410
The Potential Relationship Between The Environmental Risk Factors And Social Cognition in Psychosis
Published 2022-06-01“… Introduction In schizophrenia research, little is known about the relationship of environmental exposures with social cognition deficits. …”
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411
Postictal psychosis: presymptomatic risk factors and the need for further investigation of genetics and pharmacotherapy
Published 2006-07-01“…Considering the progress in schizophrenia research in the context of the clinical features of PIP and existing studies, potential neurobiological mechanisms for PIP are herein proposed, and further genetic analyses, which may help identify those susceptible, are warranted.…”
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412
Academic difficulties among young persons with mental disorders
Published 2022-01-01“…Materials and Methods: Semi-qualitative study was conducted in the outpatient department of the Schizophrenia Research Foundation, a mental health center and nonprofit organization based in Chennai. …”
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413
Impaired top-down modulation of saccadic latencies in patients with schizophrenia but not in first-degree relatives
Published 2015-02-01“…Impaired eye movements have a long history in schizophrenia research and meet the criteria of a reliable biomarker. …”
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414
Examining Neural Connectivity in Schizophrenia Using Task-Based EEG: A Graph Theory Approach
Published 2023-10-01“…Electroencephalography (EEG) is a valuable tool for understanding the neural dynamics and functional abnormalities associated with schizophrenia. Research studies utilizing EEG have identified specific patterns of brain activity in individuals diagnosed with schizophrenia that may reflect disturbances in neural synchronization and information processing in cortical circuits. …”
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Implications for Early Diagnosis and Treatment in Schizophrenia Due to Correlation between Auditory Perceptual Deficits and Cognitive Impairment
Published 2021-09-01“…This may have important implications in schizophrenia research, as well as in early diagnosis and nonpharmacological treatment of the disorder.…”
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416
Schizophrenia: neural architecture, brain regional differences, and changes with age
Published 2013“…A focus on the microstructure in the inferior parietal lobule, a neglected region in schizophrenia research, reveals a difference in structure in schizophrenia, as well as important relationships with age that support a progressive course to the disease. …”
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Improving quality of care among patients hospitalised with schizophrenia: a nationwide initiative
Published 2015-06-01Get full text
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418
Morphometric differences in planum temporale in schizophrenia and bipolar disorder revealed by statistical analysis of Labeled Cortical Depth Maps
Published 2014-08-01“…Statistical analyses of pooled and censored LCDM distances reveal subtle differences in PT between SCZ and BPD groups from data generated by Ratnanather et al. (Schizophrenia Research, http://dx.doi.org/10.1016/j.schres.2013.08.014). …”
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Translational aspects of the novel object recognition task in rats abstinent following sub-chronic treatment with phencyclidine (PCP): effects of modafinil and relevance to cogniti...
Published 2010-11-01“…The aim of the present study was to investigate the effects of selected antipsychotic and cognition enhancing drugs, namely haloperidol, risperidone, donepezil, and modafinil in an animal model widely used in preclinical schizophrenia research. To this end, the novel object recognition (NOR) task was applied to rats abstinent following sub-chronic treatment with PCP. …”
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Schizophrenia, the gut microbiota, and new opportunities from optogenetic manipulations of the gut-brain axis
Published 2021-06-01“…Abstract Schizophrenia research arose in the twentieth century and is currently rapidly developing, focusing on many parallel research pathways and evaluating various concepts of disease etiology. …”
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