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1681
Iterative optimization yields Mcl-1–targeting stapled peptides with selective cytotoxicity to Mcl-1–dependent cancer cells
Published 2018“…Discovering potent and selective Mcl-1 inhibitors that can relieve apoptotic blockades is thus a high priority for cancer research. …”
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1682
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1683
Next-generation cell line selection methodology leveraging data lakes, natural language generation and advanced data analytics
Published 2023-06-01“…The second step calculates a new metric referenced as the cell line manufacturability index (MICL) quantifying the performance of each clone by considering the selection criteria relevant to productivity, growth and product quality. …”
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1684
Robust Image Population Based Stain Color Normalization: How Many Reference Slides Are Enough?
Published 2022-01-01“…We seek the optimal number of slides to construct a more representative reference based on composite/aggregate of multiple H&E density histograms and stain-vectors, obtained from a randomly selected WSI population (WSI-Cohort-Subset). We utilized 1,864 IvyGAP WSIs as a WSI-cohort, and built 200 WSI-Cohort-Subsets varying in size (from 1 to 200 WSI-pairs) using randomly selected WSIs. …”
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1685
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1686
Design of a Fluxgate Weak Current Sensor with Anti-Low Frequency Interference Ability
Published 2022-11-01“…The sensor adopts the principle of fluxgate detection and adds a magnetic ring on the original basis. …”
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1687
Low-Rank Matrix Recovery from Noise via an MDL Framework-Based Atomic Norm
Published 2020-10-01“…Therefore, in this study, we employ the minimum description length (MDL) principle and atomic norm for low-rank matrix recovery to overcome these limitations. …”
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1688
Business decision-making of power generators in competitive electricity market
Published 2024-01-01“…The valuation and optimal sales strategy problems are analyzed using a risk-neutral pricing approach, dynamic programming principles, and the trinomial tree model suitable for the regime switching model. …”
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1689
Thermodynamic Origin of Negative Thermal Expansion Based on a Phase Transition-Type Mechanism in the GdF<sub>3</sub>-TbF<sub>3</sub> System
Published 2023-10-01“…For the GdF<sub>3</sub>-TbF<sub>3</sub> model system, an “operating-temperature window Δ<b><i>T</i></b>” and a two-phase composition of NTE-II materials follows from the thermodynamics of chemical systems: the phase rule and the principle of continuity. A necessary and sufficient sign of NTE-II is a combination of polymorphism and the density anomaly. …”
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1690
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1691
Evolutionary Medicine and Future of Humanity: Will Evolution Have the Final Word?
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1692
The Topology of Quantum Theory and Social Choice
Published 2022-06-01“…They also explain entanglement, the Heisenberg uncertainty principle, order dependence of observations, the conjunction fallacy and geometric phenomena such as Pancharatnam–Berry phases. …”
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1693
The Centre for Chemical Sensors and Chemical Information Technology (CCS) in Micro- and Nanotechnology
Published 2004-10-01“… A selection of the most challenging projects in micro- and nanotechnology tackled at CCS during the last few years are discussed. …”
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1694
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1695
Opening Pandora's box: caveats with using toolbox-based approaches in mathematical modeling in biology
Published 2024-01-01Get full text
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1696
Factor Analysis of XRF and XRPD Data on the Example of the Rocks of the Kontozero Carbonatite Complex (NW Russia). Part I: Algorithm
Published 2020-09-01“…This paper aims to develop a principle for selecting the most informative samples for geological research from extensive collections of rock material. …”
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1697
A Hypergraph Approach for Estimating Growth Mechanisms of Complex Networks
Published 2022-01-01“…We also treat an often-neglected selection bias in modeling the emergence of new edges with new nodes. …”
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1698
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1699
Aggregated Distribution as an Explanation for the Paradox of Plankton and Collective Animal Behavior
Published 2022-10-01“…Besides, the competitive exclusion principle does not usually stand in populations with aggregated distribution. …”
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1700
A Two-Stage Hybrid Default Discriminant Model Based on Deep Forest
Published 2021-05-01“…So, this paper constructs a two-stage hybrid default discrimination model based on multiple feature selection methods and gcForest algorithm, and at the same time, it optimizes the parameters for the lowest type II error as the first principle, and the highest AUC and accuracy as the second and third principles. …”
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