Iterative optimization yields Mcl-1–targeting stapled peptides with selective cytotoxicity to Mcl-1–dependent cancer cells by Bird, Gregory H., Ryan, Jeremy A., Godes, Marina, Pritz, Jonathan R., Letai, Anthony, Walensky, Loren D., Rezaei Araghi, Raheleh, Jenson, Justin Michael, Grant, Robert A, Keating, Amy E.

“…Discovering potent and selective Mcl-1 inhibitors that can relieve apoptotic blockades is thus a high priority for cancer research. …”
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Specialized product in the form of a biotechnological complex of bacterial metafiltrates for selective sorption of endotoxins and metabolic correction of intestinal microflora by Poznyakovsky V. M., Zakharenko M. A., Avstrievskikh A. N., Zinov'eva E. N.

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Next-generation cell line selection methodology leveraging data lakes, natural language generation and advanced data analytics by Stephen Goldrick, Haneen Alosert, Clare Lovelady, Nicholas J. Bond, Tarik Senussi, Diane Hatton, John Klein, Matthew Cheeks, Richard Turner, James Savery, Suzanne S. Farid

“…The second step calculates a new metric referenced as the cell line manufacturability index (MICL) quantifying the performance of each clone by considering the selection criteria relevant to productivity, growth and product quality. …”
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Robust Image Population Based Stain Color Normalization: How Many Reference Slides Are Enough? by Jose L. Agraz, Caleb M. Grenko, Andrew A. Chen, Angela N. Viaene, MacLean D. Nasrallah, Sarthak Pati, Tahsin Kurc, Joel Saltz, Michael D. Feldman, Hamed Akbari, Parth Sharma, Russell T. Shinohara, Spyridon Bakas

“…We seek the optimal number of slides to construct a more representative reference based on composite/aggregate of multiple H&E density histograms and stain-vectors, obtained from a randomly selected WSI population (WSI-Cohort-Subset). We utilized 1,864 IvyGAP WSIs as a WSI-cohort, and built 200 WSI-Cohort-Subsets varying in size (from 1 to 200 WSI-pairs) using randomly selected WSIs. …”
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Fiscal, Investment and Export Multipliers and the COVID-19 Pandemic Slowdowns Uncertainty Factor in the First Half of 2020 by Arkadiusz J. Derkacz

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Design of a Fluxgate Weak Current Sensor with Anti-Low Frequency Interference Ability by Xiangyu Tan, Wenyun Li, Guochao Qian, Gang Ao, Xiaowei Xu, Ran Wei, Yi Ke, Wenbin Zhang

“…The sensor adopts the principle of fluxgate detection and adds a magnetic ring on the original basis. …”
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Low-Rank Matrix Recovery from Noise via an MDL Framework-Based Atomic Norm by Anyong Qin, Lina Xian, Yongliang Yang, Taiping Zhang, Yuan Yan Tang

“…Therefore, in this study, we employ the minimum description length (MDL) principle and atomic norm for low-rank matrix recovery to overcome these limitations. …”
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Business decision-making of power generators in competitive electricity market by Lingjie Shao, Tingting Chen, Jingjing Zhu, Mengsi Li, Yiming He, Haiting Lin

“…The valuation and optimal sales strategy problems are analyzed using a risk-neutral pricing approach, dynamic programming principles, and the trinomial tree model suitable for the regime switching model. …”
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Thermodynamic Origin of Negative Thermal Expansion Based on a Phase Transition-Type Mechanism in the GdF₃-TbF₃ System by Elena A. Sulyanova, Boris P. Sobolev

“…For the GdF₃-TbF₃ model system, an “operating-temperature window Δ<b><i>T</i></b>” and a two-phase composition of NTE-II materials follows from the thermodynamics of chemical systems: the phase rule and the principle of continuity. A necessary and sufficient sign of NTE-II is a combination of polymorphism and the density anomaly. …”
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Information and Self-Organization by Hermann Haken, Juval Portugali

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Evolutionary Medicine and Future of Humanity: Will Evolution Have the Final Word? by Maciej Henneberg, Arthur Saniotis

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The Topology of Quantum Theory and Social Choice by Graciela Chichilnisky

“…They also explain entanglement, the Heisenberg uncertainty principle, order dependence of observations, the conjunction fallacy and geometric phenomena such as Pancharatnam–Berry phases. …”
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The Centre for Chemical Sensors and Chemical Information Technology (CCS) in Micro- and Nanotechnology by Ursula E. Spichiger-Keller, Prisca Schär-Zammarettia

“… A selection of the most challenging projects in micro- and nanotechnology tackled at CCS during the last few years are discussed. …”
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Modeling Magnetostrictive Transducers for Structural Health Monitoring: Ultrasonic Guided Wave Generation and Reception by Gaofeng Sha, Cliff J. Lissenden

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Opening Pandora's box: caveats with using toolbox-based approaches in mathematical modeling in biology by Vitaly V. Ganusov, Vitaly V. Ganusov

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Factor Analysis of XRF and XRPD Data on the Example of the Rocks of the Kontozero Carbonatite Complex (NW Russia). Part I: Algorithm by Ekaterina Fomina, Evgeniy Kozlov, Ayya Bazai

“…This paper aims to develop a principle for selecting the most informative samples for geological research from extensive collections of rock material. …”
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A Hypergraph Approach for Estimating Growth Mechanisms of Complex Networks by Masaaki Inoue, Thong Pham, Hidetoshi Shimodaira

“…We also treat an often-neglected selection bias in modeling the emergence of new edges with new nodes. …”
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Selection of Numerical Criterion Value for Determination of Short Circuit Type in Adaptive Micro-Processing Current Protection of Electric Power Lines by A. V. Kovalevsky

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Aggregated Distribution as an Explanation for the Paradox of Plankton and Collective Animal Behavior by Javier Falgueras-Cano, Juan Antonio Falgueras-Cano, Andrés Moya

“…Besides, the competitive exclusion principle does not usually stand in populations with aggregated distribution. …”
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A Two-Stage Hybrid Default Discriminant Model Based on Deep Forest by Gang Li, Hong-Dong Ma, Rong-Yue Liu, Meng-Di Shen, Ke-Xin Zhang

“…So, this paper constructs a two-stage hybrid default discrimination model based on multiple feature selection methods and gcForest algorithm, and at the same time, it optimizes the parameters for the lowest type II error as the first principle, and the highest AUC and accuracy as the second and third principles. …”
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