Showing 1 - 20 results of 338 for search '"Single cell genomics"', query time: 4.91s Refine Results
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    Current Challenges in Bioinformatics of Single Cell Genomics by Luwen eNing, Geng eLiu, Guibo eLi, Yong eHou, Yin eTong, Jiankui eHe

    Published 2014-01-01
    “…Single cell genomics is a rapidly growing field with many new techniques emerging in the past few years. …”
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    The impact of single-cell genomics on the field of mycobacterial infection by Inês Geraldes, Inês Geraldes, Mónica Fernandes, Mónica Fernandes, Alexandra G. Fraga, Alexandra G. Fraga, Nuno S. Osório, Nuno S. Osório

    Published 2022-09-01
    “…In addition, we aim at providing insights into current research gaps and potential future developments related to the use of single-cell genomics to study mycobacterial infection.…”
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    New array approaches to explore single cells genomes by Evelyne eVanneste, Lilach eBittman, Niels eVan der Aa, Thierry eVoet, Joris Robert Vermeesch

    Published 2012-03-01
    “…Whereas array techniques have been well established for the analysis of unamplified DNA derived from many cells, it has been more challenging to enable the accurate analysis of single cell genomes. In this review, we provide an overview of single cell DNA amplification techniques, the different array approaches and discuss their potential applications to study human embryos.…”
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    Revealing the vectors of cellular identity with single-cell genomics by Wagner, Allon, Regev, Aviv, Yosef, Nir

    Published 2018
    “…Single-cell genomics has now made it possible to create a comprehensive atlas of human cells. …”
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    Scaling single-cell genomics from phenomenology to mechanism by Tanay, Amos, Regev, Aviv

    Published 2018
    “…Initial single-cell genomic studies provided a remarkably rich phenomenology of heterogeneous cellular states, but transforming observational studies into models of dynamics and causal mechanisms in tissues poses fresh challenges and requires stronger integration of theoretical, computational and experimental frameworks.…”
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    The future is now: single-cell genomics of bacteria and archaea by Blainey, Paul C.

    Published 2014
    “…Interest in the expanding catalog of uncultivated microorganisms, increasing recognition of heterogeneity among seemingly similar cells, and technological advances in whole-genome amplification and single-cell manipulation are driving considerable progress in single-cell genomics. Here, the spectrum of applications for single-cell genomics, key advances in the development of the field, and emerging methodology for single-cell genome sequencing are reviewed by example with attention to the diversity of approaches and their unique characteristics. …”
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    Single-cell genomics for dissection of complex malaria infections. by Nair, S, Nkhoma, S, Serre, D, Zimmerman, P, Gorena, K, Daniel, B, Nosten, F, Anderson, T, Cheeseman, I

    Published 2014
    “…We demonstrate that our single-cell genomics approach can be used to generate parasite genome sequences directly from patient blood in order to unravel the complexity of P. vivax and P. falciparum infections. …”
    Journal article
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    Application of single-cell genomics in cancer: promise and challenges. by Wills, Q, Mead, A

    Published 2015
    “…Recent advances in single-cell genomics are opening up unprecedented opportunities to transform cancer genomics. …”
    Journal article
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    Charting the Complexity of the Marine Microbiome through Single-Cell Genomics by Pachiadaki, Maria G., Brown, Julia M., Brown, Joseph, Bezuidt, Oliver, Berube, Paul M., Biller, Steven, Poulton, Nicole J., Burkart, Michael D., La Clair, James J., Chisholm, Sallie (Penny), Stepanauskas, Ramunas

    Published 2020
    “…Randomized, scaled-up single-cell genomics of marine microorganisms reveals a high degree of uniqueness between individual cells, implying limited clonality within populations, and establishes that a large fraction of global genetic diversity can be recovered from a single sample, suggesting effective global dispersal of prokaryoplankton.…”
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