Imaging Mass Cytometry and Single-Cell Genomics Reveal Differential Depletion and Repletion of B-Cell Populations Following Ofatumumab Treatment in Cynomolgus Monkeys by Diethilde Theil, Paul Smith, Catherine Huck, Yoann Gilbart, Algirdas Kakarieka, David Leppert, Celine Rauld, Cindy Schmid, Reto Baumgartner, Nathalie Stuber, Francisco Cordoba, Valerie Dubost, Katy Darribat, Magali Jivkov, Wilfried Frieauff, Rainer Kneuer, Markus Stoeckli, Stefan Reinker, Keith Mansfield, José M. Carballido, Philippe Couttet, Gisbert Weckbecker

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Combination of machine learning-based bulk and single-cell genomics reveals necroptosis-related molecular subtypes and immunological features in autism spectrum disorder by Lichun Liu, Qingxian Fu, Huaili Ding, Hua Jiang, Zhidong Zhan, Yongxing Lai

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A streamlined workflow for single-cells genome-wide copy-number profiling by low-pass sequencing of LM-PCR whole-genome amplification products. by Alberto Ferrarini, Claudio Forcato, Genny Buson, Paola Tononi, Valentina Del Monaco, Mario Terracciano, Chiara Bolognesi, Francesca Fontana, Gianni Medoro, Rui Neves, Birte Möhlendick, Karim Rihawi, Andrea Ardizzoni, Semini Sumanasuriya, Penny Flohr, Maryou Lambros, Johann de Bono, Nikolas H Stoecklein, Nicolò Manaresi

“…Chromosomal instability and associated chromosomal aberrations are hallmarks of cancer and play a critical role in disease progression and development of resistance to drugs. Single-cell genome analysis has gained interest in latest years as a source of biomarkers for targeted-therapy selection and drug resistance, and several methods have been developed to amplify the genomic DNA and to produce libraries suitable for Whole Genome Sequencing (WGS). …”
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Single-Cell (Meta-)Genomics of a Dimorphic Candidatus Thiomargarita nelsonii Reveals Genomic Plasticity by Beverly E. Flood, Palmer eFliss, Daniel Seth Jones, Gregory J. Dick, Sunit eJain, Anne-Kristin eKaster, Matthias eWinkel, Marc eMußmann, Jake eBailey

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Retrospective cell lineage reconstruction in humans by using short tandem repeats by Liming Tao, Ofir Raz, Zipora Marx, Manjusha S. Ghosh, Sandra Huber, Julia Greindl-Junghans, Tamir Biezuner, Shiran Amir, Lilach Milo, Rivka Adar, Ron Levy, Amos Onn, Noa Chapal-Ilani, Veronika Berman, Asaf Ben Arie, Guy Rom, Barak Oron, Ruth Halaban, Zbigniew T. Czyz, Melanie Werner-Klein, Christoph A. Klein, Ehud Shapiro

Subjects: “…single-cell genomics…”
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Experimental Considerations for Single-Cell RNA Sequencing Approaches by Quy H. Nguyen, Nicholas Pervolarakis, Kevin Nee, Kai Kessenbrock

Subjects: “…single-cell genomics…”
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From measuring noise towards integrated single-cell biology. by Pawel ePaszek

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MichiGAN: sampling from disentangled representations of single-cell data using generative adversarial networks by Hengshi Yu, Joshua D. Welch

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Simultaneous measurement of chromatin accessibility, DNA methylation, and nucleosome phasing in single cells by Sebastian Pott

Subjects: “…single cell genomics…”
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Reconstructing mutational lineages in breast cancer by multi-patient-targeted single-cell DNA sequencing by Jake Leighton, Min Hu, Emi Sei, Funda Meric-Bernstam, Nicholas E. Navin

Subjects: “…single-cell genomics…”
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Next-Generation in vivo Modeling of Human Cancers by Gaetano Gargiulo

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DeepCpG: accurate prediction of single-cell DNA methylation states using deep learning by Christof Angermueller, Heather J. Lee, Wolf Reik, Oliver Stegle

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Clinical Perspectives of Single-Cell RNA Sequencing by Nayoung Kim, Hye Hyeon Eum, Hae-Ock Lee

Subjects: “…single-cell genomics…”
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Cellular heterogeneity in disease severity and clinical outcome: Granular understanding of immune response is key by Kriti Khare, Kriti Khare, Rajesh Pandey, Rajesh Pandey

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Genomic Variation Influences Methanothermococcus Fitness in Marine Hydrothermal Systems by Michael Hoffert, Michael Hoffert, Rika E. Anderson, Julie Reveillaud, Leslie G. Murphy, Ramunas Stepanauskas, Julie A. Huber

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Dynamics of Whole Transcriptome Analysis (WTA) and Surface markers expression (AbSeq) in Immune Cells of COVID-19 Patients and Recovered captured through Single Cell Genomics by Jyoti Soni, Jyoti Soni, Partha Chattopadhyay, Partha Chattopadhyay, Priyanka Mehta, Priyanka Mehta, Ramakant Mohite, Kishore Tardalkar, Meghnad Joshi, Rajesh Pandey, Rajesh Pandey

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A Reproducibility-Based Computational Framework Identifies an Inducible, Enhanced Antiviral State in Dendritic Cells from HIV-1 Elite Controllers by Enrique Martin-Gayo, Michael B. Cole, Kellie E. Kolb, Zhengyu Ouyang, Jacqueline Cronin, Samuel W. Kazer, Jose Ordovas-Montanes, Mathias Lichterfeld, Bruce D. Walker, Nir Yosef, Alex K. Shalek, Xu G. Yu

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Single cell transcriptomics reveals cell type specific features of developmentally regulated responses to lipopolysaccharide between birth and 5 years by James F. Read, James F. Read, Michael Serralha, Jesse D. Armitage, Jesse D. Armitage, Muhammad Munir Iqbal, Mark N. Cruickshank, Alka Saxena, Deborah H. Strickland, Deborah H. Strickland, Jason Waithman, Patrick G. Holt, Patrick G. Holt, Anthony Bosco, Anthony Bosco

Subjects: “…single cell genomics…”
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Single Cell Transcriptomics Reveal Abnormalities in Neurosensory Patterning of the Chd7 Mutant Mouse Ear by Robert Durruthy-Durruthy, Ethan D. Sperry, Ethan D. Sperry, Margot E. Bowen, Laura D. Attardi, Stefan Heller, Donna M. Martin, Donna M. Martin, Donna M. Martin

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Aneuvis: web-based exploration of numerical chromosomal variation in single cells by Daniel G. Piqué, Grasiella A. Andriani, Elaine Maggi, Samuel E. Zimmerman, John M. Greally, Cristina Montagna, Jessica C. Mar

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