SIRT6 Ameliorates Cancer Cachexia–Associated Adipose Wasting by Suppressing TNFR2 Signalling in Mice by Kang Xu, Yida Wang, Fang Wang, Yannan Guo, Yu Ren, Vivien Low, Sungyun Cho, Qingfei Liu, Ying Qiu, Xue Li, Kang Yu, Zhongchi Li, Zhao Wang

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Age-related changes of human serum Sirtuin6 in adults by Ying Zhao, Xiangli Bai, Xiong Jia, Yajing Lu, Wenzhuo Cheng, Meng Shu, Yan Zhu, Lin Zhu, Li Wang, Yan Shu, Yi Song, Si Jin

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SIRT6 polymorphism rs117385980 is associated with longevity and healthy aging in Finnish men by Katariina Hirvonen, Hannele Laivuori, Jari Lahti, Timo Strandberg, Johan G. Eriksson, Peter Hackman

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Binding to nucleosome poises human SIRT6 for histone H3 deacetylation by Ekaterina Smirnova, Emmanuelle Bignon, Patrick Schultz, Gabor Papai, Adam Ben Shem

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Epigenetic and transcriptional control of adipocyte function by centenarian-associated SIRT6 N308K/A313S mutant by Jan Frohlich, Niccolò Liorni, Manuel Mangoni, Gabriela Lochmanová, Pavlína Pírek, Nikola Kaštánková, Pille Pata, Jan Kucera, George N. Chaldakov, Anton B. Tonchev, Illar Pata, Vera Gorbunova, Eric Leire, Zbyněk Zdráhal, Tommaso Mazza, Manlio Vinciguerra

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Sirt6 Mono‐ADP‐Ribosylates YY1 to Promote Dystrophin Expression for Neuromuscular Transmission by Wei Zhang, Lei Bai, Wentao Xu, Jun Liu, Yi Chen, Weiqiang Lin, Huasong Lu, Binwei Wang, Benyan Luo, Guoping Peng, Kejing Zhang, Chengyong Shen

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Boosting ATM activity alleviates aging and extends lifespan in a mouse model of progeria by Minxian Qian, Zuojun Liu, Linyuan Peng, Xiaolong Tang, Fanbiao Meng, Ying Ao, Mingyan Zhou, Ming Wang, Xinyue Cao, Baoming Qin, Zimei Wang, Zhongjun Zhou, Guangming Wang, Zhengliang Gao, Jun Xu, Baohua Liu

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Cyclosporine modulates neutrophil functions via the SIRT6–HIF‐1α–glycolysis axis to alleviate severe ulcerative colitis by Huiying Lu, Jian Lin, Chunjin Xu, Mingming Sun, Keqiang Zuo, Xiaoping Zhang, Mingsong Li, Hailiang Huang, Zhong Li, Wei Wu, Baisui Feng, Zhanju Liu

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SIRT6通过调节eNOS抑制心肌肥大的机制研究

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SIRT6 Is Involved in the Progression of Ovarian Carcinomas via β-Catenin-Mediated Epithelial to Mesenchymal Transition by Jun Sang Bae, Jun Sang Bae, Jun Sang Bae, Sang Jae Noh, Sang Jae Noh, Kyoung Min Kim, Kyoung Min Kim, Kyoung Min Kim, See-Hyoung Park, Usama Khamis Hussein, Usama Khamis Hussein, Ho Sung Park, Ho Sung Park, Ho Sung Park, Byung-Hyun Park, Sang Hoon Ha, Ho Lee, Myoung Ja Chung, Myoung Ja Chung, Myoung Ja Chung, Woo Sung Moon, Woo Sung Moon, Woo Sung Moon, Dong Hyu Cho, Dong Hyu Cho, Dong Hyu Cho, Kyu Yun Jang, Kyu Yun Jang, Kyu Yun Jang, Kyu Yun Jang

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SIRT6 deficiency impairs the deacetylation and ubiquitination of UHRF1 to strengthen glycolysis and lactate secretion in bladder cancer by Xiaojing Wang, Peipei Zhang, Jiaqi Yan, Jingyi Huang, Yan Shen, Hongchao He, Hongjing Dou

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SIRT6 drives epithelial-to-mesenchymal transition and metastasis in non-small cell lung cancer via snail-dependent transrepression of KLF4 by Ziming Li, Jia Huang, Shengping Shen, Zhenping Ding, Qingquan Luo, Zhiwei Chen, Shun Lu

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Ginsenosides Rc, as a novel SIRT6 activator, protects mice against high fat diet induced NAFLD by Zehong Yang, Yuanyuan Yu, Nannan Sun, Limian Zhou, Dong Zhang, HaiXin Chen, Wei Miao, Weihang Gao, Canyang Zhang, Changhui Liu, Xiaoying Yang, Xiaojie Wu, Yong Gao

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Sirt6 regulates efficiency of mouse somatic reprogramming and maintenance of pluripotency by Peng Xu, Ting-ting Wang, Xiu-zhen Liu, Nan-Yu Wang, Li-hong Sun, Zhu-qin Zhang, Hou-zao Chen, Xiang Lv, Yue Huang, De-Pei Liu

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Myeloid-Specific SIRT6 Deletion Protects Against Particulate Matter (PM2.5)-Induced Airway Inflammation by Chen S, Wu M, Xiong Z, Huang J, Lv Y, Li Y, Zeng M, Lai T

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Inhibition of SIRT6 potentiates the anti-tumor effect of doxorubicin through suppression of the DNA damage repair pathway in osteosarcoma by Zhongkai Zhang, Sang Hoon Ha, Young Jae Moon, Usama Khamis Hussein, Yiping Song, Kyoung Min Kim, See-Hyoung Park, Ho Sung Park, Byung-Hyun Park, Ae-Ri Ahn, Sang-A Lee, Su Jin Ahn, Jung Ryul Kim, Kyu Yun Jang

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Metabolic Imbalance Effect on Retinal Müller Glial Cells Reprogramming Capacity: Involvement of Histone Deacetylase SIRT6 by L Francisco Sanhueza Salas, Alfredo García-Venzor, Alfredo García-Venzor, Natalia Beltramone, Claudia Capurro, Debra Toiber, Debra Toiber, Dafne Magalí Silberman

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SIRT6 Suppresses Cancer Stem-like Capacity in Tumors with PI3K Activation Independently of Its Deacetylase Activity by Rafael M. Ioris, Mirco Galié, Giorgio Ramadori, Jason G. Anderson, Anne Charollais, Georgia Konstantinidou, Xavier Brenachot, Ebru Aras, Algera Goga, Nicholas Ceglia, Carlos Sebastián, Denis Martinvalet, Raul Mostoslavsky, Pierre Baldi, Roberto Coppari

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SIRT6 Widely Regulates Aging, Immunity, and Cancer by Yunjia Li, Jing Jin, Yi Wang, Yi Wang

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Skeletal muscle‐specific over‐expression of the nuclear sirtuin SIRT6 blocks cancer‐associated cachexia by regulating multiple targets by Sadhana A. Samant, Vinodkumar B. Pillai, Mahesh P. Gupta

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