The post-translational modification O-GlcNAc is a sensor and regulator of metabolism by Murielle M. Morales, Matthew R. Pratt

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Microtubule plus-ends within a mitotic cell are ‘moving platforms’ with anchoring, signalling and force-coupling roles by Naoka Tamura, Viji M. Draviam

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Ex vivo mammalian prions are formed of paired double helical prion protein fibrils by Cassandra Terry, Adam Wenborn, Nathalie Gros, Jessica Sells, Susan Joiner, Laszlo L. P. Hosszu, M. Howard Tattum, Silvia Panico, Daniel K. Clare, John Collinge, Helen R. Saibil, Jonathan D. F. Wadsworth

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Differing requirements for Augmin in male meiotic and mitotic spindle formation in Drosophila by Matthew S. Savoian, David M. Glover

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Amphibians with infectious disease increase their reproductive effort: evidence for the terminal investment hypothesis by Laura A. Brannelly, Rebecca Webb, Lee F. Skerratt, Lee Berger

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Telomeric replication stress: the beginning and the end for alternative lengthening of telomeres cancers by Robert Lu, Hilda A. Pickett

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Dual role of the chromatin-binding factor PHF13 in the pre- and post-integration phases of HIV-1 replication by Stephan Hofmann, Sandra Dehn, Ramona Businger, Sebastian Bolduan, Martha Schneider, Zeger Debyser, Ruth Brack-Werner, Michael Schindler

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Metamorphic proteins: the Janus proteins of structural biology by Kulkarni Madhurima, Bodhisatwa Nandi, Ashok Sekhar

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Hidden in plain sight: what remains to be discovered in the eukaryotic proteome? by Valerie Wood, Antonia Lock, Midori A. Harris, Kim Rutherford, Jürg Bähler, Stephen G. Oliver

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Narrative Medicine Under the Guidance of Traditional Chinese Medicine Theory by Chunyong WANG

“…By adopting the theory of TCM, the author attempted to provide the patients with systematic treatment from the perspective of society-psychology-biology under the guidance of both the unity of Heaven and Man, and the unity of Xing (Body) and Shen (Mind/Spirit) through his clinical practice. …”
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Are we there yet? Initial targeting of the Male-Specific Lethal and Polycomb group chromatin complexes in Drosophila by Kyle A. McElroy, Hyuckjoon Kang, Mitzi I. Kuroda

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Installation of LYRM proteins in early eukaryotes to regulate the metabolic capacity of the emerging mitochondrion by Vít Dohnálek, Pavel Doležal

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A quantitative account of mammalian rod phototransduction with PDE6 dimeric activation: responses to bright flashes by Trevor D. Lamb, Timothy W. Kraft

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Single-cell expression predicts neuron-specific protein homeostasis networks by Sebastian Pechmann

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A closed conformation of the Caenorhabditis elegans separase–securin complex by Gudrun Bachmann, Mark W. Richards, Anja Winter, Fabienne Beuron, Edward Morris, Richard Bayliss

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Molecular anatomy of the pre-primitive-streak chick embryo by Hyung Chul Lee, Hui-Chun Lu, Mark Turmaine, Nidia M. M. Oliveira, Youwen Yang, Irene De Almeida, Claudio D. Stern

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The Pseudomonas aeruginosa ExoY phenotype of high-copy-number recombinants is not detectable in natural isolates by Antje Munder, Justin Rothschuh, Bastian Schirmer, Jens Klockgether, Volkhard Kaever, Burkhard Tümmler, Roland Seifert, Christina Kloth

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Cellular parabiosis and the latency of age-related diseases by Miroslav Radman

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Stepwise order in protein complex assembly: approaches and emerging themes by Michael T. Brown, Michael A. McMurray

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Targeting the INCENP IN-box–Aurora B interaction to inhibit CPC activity in vivo by Florence H. Gohard, Daniel J. St-Cyr, Mike Tyers, William C. Earnshaw

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