MethylRAD: a simple and scalable method for genome-wide DNA methylation profiling using methylation-dependent restriction enzymes by Shi Wang, Jia Lv, Lingling Zhang, Jinzhuang Dou, Yan Sun, Xue Li, Xiaoteng Fu, Huaiqian Dou, Junxia Mao, Xiaoli Hu, Zhenmin Bao

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Coiled-coil-mediated dimerization of Atg16 is required for binding to the PROPPIN Atg21 by Miranda Bueno-Arribas, Celia Cruz-Cuevas, María-Angeles Navas, Ricardo Escalante, Olivier Vincent

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The contribution of non-essential Schizosaccharomyces pombe genes to fitness in response to altered nutrient supply and target of rapamycin activity by Shervi Lie, Peter Banks, Conor Lawless, David Lydall, Janni Petersen

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Greatwall-Endos-PP2A/B55Twins network regulates translation and stability of maternal transcripts in the Drosophila oocyte-to-embryo transition by Hélène Rangone, Laura Bond, Timothy T. Weil, David M. Glover

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Peripheral self-reactivity regulates antigen-specific CD8 T-cell responses and cell division under physiological conditions by Lee Kim Swee, Zhen Wei Tan, Anna Sanecka, Nagisa Yoshida, Harshil Patel, Gijsbert Grotenbreg, Eva-Maria Frickel, Hidde L. Ploegh

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The pivotal role of osteopontin in UV-induced skin inflammation in a mouse model by Haesoo Kim, Chang-Yup Shin, Chi-Hyun Park, Dong Hun Lee, Si-Hyung Lee, Jin Ho Chung

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Serum amyloid P component accumulates and persists in neurones following traumatic brain injury by Ping K. Yip, Zhou-Hao Liu, Shumaila Hasan, Mark B. Pepys, Christopher E. G. Uff

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Phylogenomics-guided discovery of a novel conserved cassette of short linear motifs in BubR1 essential for the spindle checkpoint by Eelco Tromer, Debora Bade, Berend Snel, Geert J. P. L. Kops

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Revisiting the origin of interleukin 1 in anamniotes and sub-functionalization of interleukin 1 in amniotes by Eva Hasel de Carvalho, Eva Bartok, Helen Stölting, Baubak Bajoghli, Maria Leptin

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Modelling T-cell immunity against hepatitis C virus with liver organoids in a microfluidic coculture system by Vaishaali Natarajan, Camille R. Simoneau, Ann L. Erickson, Nathan L. Meyers, Jody L. Baron, Stewart Cooper, Todd C. McDevitt, Melanie Ott

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Delay eyeblink conditioning performance and brain-wide c-Fos expression in male and female mice by Maria Roa Oyaga, Ines Serra, Devika Kurup, Sebastiaan K. E. Koekkoek, Aleksandra Badura

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Two-step phosphorylation of Ana2 by Plk4 is required for the sequential loading of Ana2 and Sas6 to initiate procentriole formation by Nikola S. Dzhindzhev, George Tzolovsky, Zoltan Lipinszki, Mohammed Abdelaziz, Janus Debski, Michal Dadlez, David M. Glover

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PK1 from Drosophila obscurin is an inactive pseudokinase with scaffolding properties by Thomas Zacharchenko, Till Dorendorf, Nicolas Locker, Evert Van Dijk, Anja Katzemich, Kay Diederichs, Belinda Bullard, Olga Mayans

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Pseudogenization of NK3 homeobox 2 (Nkx3.2) in monotremes provides insight into unique gastric anatomy and physiology by Jackson Dann, Zhipeng Qu, Linda Shearwin-Whyatt, Rachel van der Ploeg, Frank Grützner

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Paracrine interactions through FGFR1 and FGFR2 receptors regulate the development of preimplantation mouse chimaeric embryo by Katarzyna Krawczyk, Katarzyna Wilczak, Katarzyna Szczepańska, Marek Maleszewski, Aneta Suwińska

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Osmolarity-regulated swelling initiates egg activation in Drosophila by Anna H. York-Andersen, Benjamin W. Wood, Elise L. Wilby, Alexander S. Berry, Timothy T. Weil

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Cytokines and growth factors cross-link heparan sulfate by Elisa Migliorini, Dhruv Thakar, Jens Kühnle, Rabia Sadir, Douglas P. Dyer, Yong Li, Changye Sun, Brian F. Volkman, Tracy M. Handel, Liliane Coche-Guerente, David G. Fernig, Hugues Lortat-Jacob, Ralf P. Richter

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The evolutionary dynamics that retain long neutral genomic sequences in face of indel deletion bias: a model and its application to human introns by Gil Loewenthal, Elya Wygoda, Natan Nagar, Lior Glick, Itay Mayrose, Tal Pupko

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Optogenetically engineered calcium oscillations promote autophagy-mediated cell death via AMPK activation by Yi-Shyun Lai, Meng-Ru Hsieh, Thi My Hang Nguyen, Ying-Chi Chen, Hsueh-Chun Wang, Wen-Tai Chiu

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A simple inland culture system provides insights into ascidian post-embryonic developmental physiology by Birthe Thuesen Mathiesen, Mayu Ohta, Boris Pinto De Magalhaes, Chiara Castelletti, Vincenzo Perria, Keaton Schuster, Lionel Christiaen, Naoyuki Ohta

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